Virus Isolation from the First Patient with SARS-CoV-2 in Korea.

Abstract:

:Novel coronavirus (SARS-CoV-2) is found to cause a large outbreak started from Wuhan since December 2019 in China and SARS-CoV-2 infections have been reported with epidemiological linkage to China in 25 countries until now. We isolated SARS-CoV-2 from the oropharyngeal sample obtained from the patient with the first laboratory-confirmed SARS-CoV-2 infection in Korea. Cytopathic effects of SARS-CoV-2 in the Vero cell cultures were confluent 3 days after the first blind passage of the sample. Coronavirus was confirmed with spherical particle having a fringe reminiscent of crown on transmission electron microscopy. Phylogenetic analyses of whole genome sequences showed that it clustered with other SARS-CoV-2 reported from Wuhan.

journal_name

J Korean Med Sci

authors

Park WB,Kwon NJ,Choi SJ,Kang CK,Choe PG,Kim JY,Yun J,Lee GW,Seong MW,Kim NJ,Seo JS,Oh MD

doi

10.3346/jkms.2020.35.e84

subject

Has Abstract

pub_date

2020-02-24 00:00:00

pages

e84

issue

7

eissn

1011-8934

issn

1598-6357

pii

35.e84

journal_volume

35

pub_type

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