Eosinophilic fasciitis preceding relapse of peripheral T-cell lymphoma.

Abstract:

:Although eosinophilic fasciitis (EF) may precede hematologic malignancy or Hodgkin's disease, association with peripheral T-cell lymphoma (PTCL) is extremely rare. Only four cases of EF preceding or concomitant PTCL have been reported in the world literature. We experienced the first Korean case of EF complicated by the later relapse of peripheral T-cell lymphoma. A 63-year-old Korean male has been followed at our outpatient clinic periodically after treatment for stage IV PTCL. He had been in complete remission for seven and a half years when he developed edema of both lower extremities followed by sclerodermatous skin change in both hands with peripheral eosinophilia. Biopsy from the left hand showed fibrous thickening of the fascia with lymphoplasmacytic and eosinophilic infiltrate, consistent with EF. Twenty-five months later, a newly developed lymph node from the left neck showed recurrence of PTCL. EF may occur as a paraneoplastic syndrome associated with the relapse of PTCL. Therefore, in a patient with EF, the possibility of coexisting and/or future occurrence of hematologic neoplasm should be considered.

journal_name

J Korean Med Sci

authors

Kim H,Kim MO,Ahn MJ,Lee YY,Jung TJ,Choi IY,Kim IS,Park CK

doi

10.3346/jkms.2000.15.3.346

keywords:

subject

Has Abstract

pub_date

2000-06-01 00:00:00

pages

346-50

issue

3

eissn

1011-8934

issn

1598-6357

journal_volume

15

pub_type

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