Relationship between chronic kidney disease and risk of coronary heart disease in Korean men.

Abstract:

:There have been many epidemiological researches of chronic kidney disease (CKD), accompanied by an increase in the incidence of coronary heart disease (CHD). However, as far as we know, little research has been done to examine the extent of the relationship between CKD and CHD as estimated by Framingham risk score (FRS) in Korean men. CKD was defined as either proteinuria or an eGFR of < 60 mL/min per 1.73 m(2). The FRS has been used to predict the 10-yr risk of coronary events and usually divided into three levels of risk < 10% (low), 10%-19% (intermediate) and ≥ 20% (high). We defined FRS ≥ 10% as more-than-a-moderate CHD risk group and FRS ≥ 20% as a high CHD risk group, respectively. After adjusting for covariates, multivariable-adjusted logistic regression analyses showed a strong statistical significant relationship between CKD and high risk of CHD (adjusted OR, 1.95 [95% CI, 1.32-2.87]). Dipstick urinalysis and eGFR can be readily measured in most clinical settings. The measurement of kidney function may represent a relatively inexpensive and efficient way to identify individuals at higher risk for CHD.

journal_name

J Korean Med Sci

authors

Ryoo JH,Kim SG,Suh BS,Kim DI,Park SK

doi

10.3346/jkms.2011.26.6.753

subject

Has Abstract

pub_date

2011-06-01 00:00:00

pages

753-8

issue

6

eissn

1011-8934

issn

1598-6357

journal_volume

26

pub_type

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