Abnormal morphological patterns of the left ventricular myocardium in the critical stenosis of the aortic valve and the intact ventricular septum.

abstract：:This study investigated the production of stromal cell-derived factor-1 (SDF-1) and the expression of CXCR4 in human bone marrow endothelial cells (BMECs). Human BMEC cell line BMEC-1 cells expressed SDF-1 mRNA, and conditioned medium induced chemoattraction of CD34+ cells. Migration was not inhibited by pretreating t...

journal_title：Journal of Korean medical science

authors： Yun HJ,Jo DY

更新日期：2003-10-01 00:00:00

abstract：:Methylenetetrahydrofolate reductase (MTHFR), a critical enzyme in folate metabolism, plays an important role in DNA methylation. It has been suggested that abnormal DNA methylation contributes to the pathogenesis of schizophrenia and congenital anomalies. The previous findings regarding the genetic relationship betwee...

journal_title：Journal of Korean medical science

authors： Kim SG,Song JY,Joo EJ,Jeong SH,Kim SH,Lee KY,Lee NY,Ahn YM,Kim YS,Roh MS

更新日期：2011-10-01 00:00:00

abstract：:It has been suggested that there is an association between environmental, low-level arsenic exposure and the risk of diabetes mellitus (DM), but little research has been conducted. Here, the glucose tolerance status and urinary creatinine adjusted total arsenic concentrations were analyzed in 3,602 subjects ≥ 20 yr of...

journal_title：Journal of Korean medical science

authors： Rhee SY,Hwang YC,Woo JT,Chin SO,Chon S,Kim YS

更新日期：2013-06-01 00:00:00

abstract：:Miyoshi myopathy (MM) is an autosomal recessive distal muscular dystrophy caused by mutations in the dysferlin gene (DYSF) on chromosome 2p13. Although MM patients and their mutations in the DYSF gene have been found from all over the world, there is only one report of genetically confirmed case of MM in Korea. Recent...

journal_title：Journal of Korean medical science

authors： Cho HJ,Sung DH,Kim EJ,Yoon CH,Ki CS,Kim JW

更新日期：2006-08-01 00:00:00

abstract：:Neuroblastomas originating from different sites might have different clinical and biological characteristics. In the present study, the clinical (age, sex and stage) and biological (N-myc amplification, Shimada pathology and levels of lactate dehydrogenase, ferritin and neuron-specific enolase) characteristics of pati...

journal_title：Journal of Korean medical science

authors： Sung KW,Yoo KH,Koo HH,Kim JY,Cho EJ,Seo YL,Kim J,Lee SK

更新日期：2009-06-01 00:00:00

abstract：:Protein C is the central component of a major anti-thrombotic regulatory system and individuals with hereditary protein C deficiency (PCD) tend to have an increased risk of thromboembolism. During the last several years, mutations causing PCD have been identified in Western countries and in Japanese. In the present st...

journal_title：Journal of Korean medical science

authors： Song KS,Park YS,Choi CR,Kim HK,Park Q,Kim HS

更新日期：1998-04-01 00:00:00

abstract：:The pneumonia severity index (PSI) and CURB-65 are widely used tools for the prediction of community-acquired pneumonia (CAP). This study was conducted to evaluate validation of severity scoring system including the PSI and CURB-65 scores of Korean CAP patients. In the prospective CAP cohort (participated in by 14 hos...

journal_title：Journal of Korean medical science

authors： Kim HI,Kim SW,Chang HH,Cha SI,Lee JH,Ki HK,Cheong HS,Yoo KH,Ryu SY,Kwon KT,Lee BK,Choo EJ,Kim DJ,Kang CI,Chung DR,Peck KR,Song JH,Suh GY,Shim TS,Kim YK,Kim HY,Moon CS,Lee HK,Park SY,Oh JY,Jung SI,Park

更新日期：2013-09-01 00:00:00

abstract：:We investigated the association between socioeconomic status and hypertension in Korea, a country that has experienced a dynamic socioeconomic transition. We analyzed participants of a prospective cohort study-the Korean Genome and Epidemiology Study-enrolled between 2001 and 2003. We recruited 7,089 subjects who unde...

journal_title：Journal of Korean medical science

authors： Park CS,Ha KH,Kim HC,Park S,Ihm SH,Lee HY

更新日期：2016-12-01 00:00:00

abstract：:X-linked hyper-IgM syndrome (XHIM) is a rare primary immunodeficiency disorder, caused by mutations of the gene encoding CD40 ligand (CD40L; CD154). We report the clinical manifestations and mutational analysis of the CD40L gene observed in a male patient from a XHIM family. Having hypogammaglobulinemia and elevated I...

journal_title：Journal of Korean medical science

authors： Jo EK,Kim HS,Lee MY,Iseki M,Lee JH,Song CH,Park JK,Hwang TJ,Kook H

更新日期：2002-02-01 00:00:00

abstract：:We determined the relationship between the progression of immunoglobulin A nephropathy (IgAN) and the A1818T polymorphism in intron 2 of Angiotensin II type 2 receptor (AT2R) gene, which might play protective roles in the pathogenesis of IgAN. Patients with biopsy-proven IgAN were recruited from the registry of the Pr...

journal_title：Journal of Korean medical science

authors： Yoon HJ,Chin HJ,Na KY,Chae DW,Kim S,Jeon US,Chung WK,Lee HH,Yang J,Kim S,Kwon YJ,Kim HC,Park SB,Kim HY,Lee TW,Progressive REnal disease and Medical Informatics and gEnomics Research (PREMIER) members.

更新日期：2009-01-01 00:00:00

abstract：:Clear-cell chondrosarcoma, a recently specified entity, is a low-grade malignant tumor and has characteristic clinical, roentgenographic and pathologic findings which separate it from conventional chondrosarcoma and other benign tumors. Therefore, correct diagnosis is important from the viewpoint of both prognosis and...

journal_title：Journal of Korean medical science

authors： Lee SD,Ahn GH,Chi JG,Ham EK

更新日期：1989-09-01 00:00:00

abstract：:Japanese hop (Hop J) pollen has been considered as one of the major causative pollen allergens in the autumn season. We developed a new Hop J immunotherapy extract in collaboration with Allergopharma (Reinbeck, Germany) and investigated immunologic mechanisms during 3 yr immunotherapy. Twenty patients (13 asthma with ...

journal_title：Journal of Korean medical science

authors： Ye YM,Lee SK,Kim SH,Nahm DH,Suh CH,Park HS

更新日期：2006-10-01 00:00:00

abstract：:The purpose of study was to determine the incidence of hip fracture in 2001, to compare this with that of 1991, and to identify possible causes of change. Patients aged 50 yr or more living in Gwangju City and Chonnam Province, Korea, and who sustained a fracture of the hip during 2001 were investigated. Only patients...

journal_title：Journal of Korean medical science

authors： Rowe SM,Song EK,Kim JS,Lee JY,Park YB,Bae BH,Hur CI

更新日期：2005-08-01 00:00:00

abstract：:This study was conducted to evaluate the influence of alcohol consumption on the risk of ocular trauma. We retrospectively reviewed the medical records of 1,024 patients who visited emergency department and received ophthalmologic examination from January 1 to December 31, 2009. The patients were divided into 2 groups...

journal_title：Journal of Korean medical science

authors： Han SB,Yang HK,Woo SJ,Hyon JY,Hwang JM

更新日期：2011-05-01 00:00:00

abstract：:The aim of this study was to compare the impacts of terazosin and tamsulosin, on prostate activity, i.e., serum prostate-specific antigen, total prostate volume (TPV), and transition zone volume (TZV). A total of 90 patients who presented with lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplas...

journal_title：Journal of Korean medical science

authors： Paick JS,Cho MC,Song SH,Kim SW,Ku JH

更新日期：2008-06-01 00:00:00

abstract：:Gestational diabetes mellitus (GDM) is a strong predictor of postpartum prediabetes and transition to overt type 2 diabetes (T2DM). Although many reports indicate that low magnesium is correlated with deteriorated glucose tolerance, the association between postpartum serum magnesium level and the risk for T2DM in wome...

journal_title：Journal of Korean medical science

authors： Yang SJ,Hwang SY,Baik SH,Lee KW,Nam MS,Park YS,Woo JT,Kim YS,Park S,Park SY,Yim CH,Yoon HK,Kim SH

更新日期：2014-01-01 00:00:00

abstract：:Tumor-to-tumor metastasis is rare. We report a case of metastatic renal cell carcinoma in meningioma. A 67-year-old woman presented a two-week history of motor dysphagia and decreased short-term memory. She had undergone a left radical nephrectomy for a renal cell carcinoma 7 years ago, and had not received any adjuva...

journal_title：Journal of Korean medical science

authors： Han HS,Kim EY,Han JY,Kim YB,Hwang TS,Chu YC

更新日期：2000-10-01 00:00:00

abstract：:We aimed to investigate the clinical value of persistent but downgraded vesicoureteral reflux (VUR) after dextranomer/hyaluronic acid (Dx/HA) injection in children. The medical records of 128 children (195 ureters) who underwent Dx/HA injections for VUR were reviewed. The incidences of pre- and post-operative febrile ...

journal_title：Journal of Korean medical science

authors： Baek M,Kang MY,Lee HE,Park K,Choi H

更新日期：2013-07-01 00:00:00

abstract：:Perinatal stroke in neonates can lead to disability in later life. However, its etiology and prognosis are poorly understood. The aim of this study was to describe clinical presentations and neurodevelopmental outcomes of our case series of perinatal stroke in Korea. Thirteen term and preterm neonates who were diagnos...

journal_title：Journal of Korean medical science

authors： Lee HJ,Lim BC,Hwang H,Hong JS,Kim EK,Kim HS,Kim BI,Choi JH,Choi CW

更新日期：2010-06-01 00:00:00

abstract：:Clinical research registration is required in many countries to improve transparency of clinical research and to ensure subject safety. Developed in February 2010, the Clinical Research Information Service (CRIS) is an online registration system for clinical studies in Korea and one of the primary registries of the Wo...

journal_title：Journal of Korean medical science

authors： Choi EK,Kim MJ,Lim NK,Park HY

更新日期：2016-01-01 00:00:00

abstract：:Microarray analysis was used to investigate the lack of identified mammalian target of rapamycin (mTOR) pathway downstream genes to overcome cross-talk at non-muscle invasive high-grade (HG)-urothelial carcinoma (UC) of the bladder, gene expression patterns, gene ontology, and gene clustering by triple (p70S6K, S6K, a...

journal_title：Journal of Korean medical science

authors： Jin S,Chang IH,Kim JW,Whang YM,Kim HJ,Hong SA,Lee TJ

更新日期：2017-08-01 00:00:00

abstract：:This study was to clarify whether Behcet's disease (BD) could be classified into the spondyloarthropathy (SpA) complex. It was undertaken on 58 patients with BD (BD group), 56 patients with SpA (SpA group), and 3 patients who concurrently satisfied the criteria for BD and SpA (BDSpA group). The clinical parameters and...

journal_title：Journal of Korean medical science

authors： Chang HK,Lee DH,Jung SM,Choi SJ,Kim JU,Choi YJ,Baek SK,Cheon KS,Cho EH,Won KS

更新日期：2002-08-01 00:00:00

abstract：:Accessory ovary is a rare gynecologic condition, and tumors arising in accessory ovaries are extremely rare. Accessory ovary may result from separation of migrating ovaries during embryogenesis and injuries such as inflammation and operation on normal ovary. Congenital malformations, most frequently malformations of t...

journal_title：Journal of Korean medical science

authors： Lim MC,Park SJ,Kim SW,Lee BY,Lim JW,Lee JH,Huh CY

更新日期：2004-06-01 00:00:00

abstract：:Coexpression of Kit ligand and c-kit has been reported in some gynecologic tumors. To determine whether imatinib mesylate is useful in ovarian epithelial tumors, we performed immunohistochemical and mutational analysis. The cases consisted of 33 cases, which included 13 serous cystadenocarcinomas, 1 borderline serous ...

journal_title：Journal of Korean medical science

authors： Kim DJ,Lee MH,Park TI,Bae HI

更新日期：2006-02-01 00:00:00

abstract：:Although the prevalence of interracial marriages in Korea is increasing, little is known regarding the pregnancy outcomes of interracial couples. The aim of this study was to investigate the differences in pregnancy outcomes between Korean and interracial Korean-foreign couples. Data for infants born in 2011 and 2012 ...

journal_title：Journal of Korean medical science

authors： Yang SY,Jung US,Hong HR,Hwang SY,Oh MJ,Kim HJ,Cho GJ

更新日期：2017-10-01 00:00:00

abstract：:NAD(P)H oxidase plays an important role in hypertension and its complication in aldosterone-salt rat. We questioned whether NAD(P)H oxidase subunit expression and activity are modulated by aldosterone and whether this is associated with target-organ damage. Rats were infused with aldosterone (0.75 microg/hr/day) for 6...

journal_title：Journal of Korean medical science

authors： Park YM,Lim BH,Touyz RM,Park JB

更新日期：2008-12-01 00:00:00

abstract：:Human metapneumovirus (HMPV) shares clinical and epidemiological characteristics with well-known respiratory syncytial virus (RSV). The aim of this study was to investigate the clinical and epidemiological differences between HMPV- and RSV-induced wheezing illnesses. A total of 1,008 nasopharyngeal aspirate specimens ...

journal_title：Journal of Korean medical science

authors： Kim CK,Choi J,Callaway Z,Kim HB,Chung JY,Koh YY,Shin BM

更新日期：2010-03-01 00:00:00

abstract：:Previous exposure to antimicrobials is a major risk factor for Clostridioides difficile infection (CDI). Antibiotic prescription and C. difficile toxin assay records of patients admitted to a tertiary hospital in Korea from 2009 to 2013 were collected to investigate the association between antibiotic consumption and C...

journal_title：Journal of Korean medical science

authors： Kim B,Kim J,Pai H

更新日期：2020-12-07 00:00:00

abstract：:A 25-yr-old woman presented with a right pleural effusion. Destruction of 9th through 12th ribs, adjacent vertebral bodies, and transverse processes was noted on plain radiograph and a large low-attenuated, irregular shaped mass lesion with peripheral rim enhancement, destroying vertebral body and transverse process, ...

journal_title：Journal of Korean medical science

authors： Lee WS,Kim SH,Kim I,Kim HK,Lee KS,Lee SY,Heo DS,Jang BS,Bang YJ,Kim NK

更新日期：2002-12-01 00:00:00

abstract：:Most of malignant tumors arising in ovarian and extraovarian endometriosis are carcinomas. Mixed mullerian tumor and endometrial stromal sarcoma arising in intestinal endometriosis are rarely described, but its clinicopathologic features have not been well characterized. Here we report a case of endometrial stromal sa...

journal_title：Journal of Korean medical science

authors： Cho HY,Kim MK,Cho SJ,Bae JW,Kim I

更新日期：2002-06-01 00:00:00