Effect of gamma-hexachlorocyclohexane (lindane) on carp (Cyprinus carpio). I. Effect of chronic intoxication on humoral immunity in relation to tissue pollutant levels.

Abstract:

:Lindane, the gamma-isomer of hexachlorocyclohexane, one of the most widely used insecticides, was incorporated into carp food for 109 days. The effects of 10, 100, or 1000 ppm of lindane in food on hematocrits and on antibody production against Yersinia ruckeri bacterin in sera and mucus were followed for 79 days. No effect of lindane on these parameters and on spleen weight was observed. Lymphoid organs, spleen and kidney, were as highly contaminated at the beginning of the inoculation (Day 30) as at the end of the experiment. The tissue levels of lindane in liver, spleen, kidney, or whole body, determinated after 30 and 109 days of contamination, indicated that the tissue distribution was dependent on organ lipid contents.

journal_name

Ecotoxicol Environ Saf

authors

Cossarini-Dunier M,Monod G,Demael A,Lepot D

doi

10.1016/0147-6513(87)90032-7

subject

Has Abstract

pub_date

1987-06-01 00:00:00

pages

339-45

issue

3

eissn

0147-6513

issn

1090-2414

pii

0147-6513(87)90032-7

journal_volume

13

pub_type

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