当前位置： SCI文献检索 > ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY期刊下所有文献 > Estradiol reduces cumulative mercury and associated disturbances in the hypothalamus-pituitary axis of ovariectomized rats.

Estradiol reduces cumulative mercury and associated disturbances in the hypothalamus-pituitary axis of ovariectomized rats.

Abstract：

:The aim of this research was to verify the incidence of endocrine dysfunction associated with mercury intoxication in the hypothalamus-pituitary reproductive system of normally cycling or castrated female rats and the possible protective action of estrogen replacement therapy. We found no differences in the frequency of estrus cycle stages (diestrus I, diestrus II, proestrus, and estrus) in normally cycling female rats during 54 days of daily oral administration of 0.004, 0.02, and 1 mg/kg MeHgCl. Conversely, the higher dose (1 mg/kg) induced a significant decrease in content of luteinizing hormone releasing hormone (LHRH) into the medial hypothalamus when administered daily during 3 days in ovariectomized rats. This effect was associated with increased levels of mercury found in the anterior pituitary gland and medial hypothalamus, rather than the anterior and posterior hypothalamus, striatum or cerebellum. A decrease in plasma levels of luteinizing hormone (LH) was also detected after administration of 7.5 mg/kg MeHgCl. These disturbances in LHRH and LH secretion induced by mercury were abolished or superimposed (respectively) by estrogenic replacement therapy (0.025 mg/kg 17beta estradiol cypionate, intramuscular). These effects were associated with a significant reduction in mercury content of the anterior pituitary gland and medial hypothalamus, suggesting a protective estrogenic effect.

journal_name

Ecotoxicol Environ Saf

journal_title

Ecotoxicology and environmental safety

authors

Oliveira FR,Ferreira JR,dos Santos CM,Macêdo LE,de Oliveira RB,Rodrigues JA,do Nascimento JL,Faro LR,Diniz DL

doi

10.1016/j.ecoenv.2004.12.024

keywords:

subject

Has Abstract

pub_date

2006-03-01 00:00:00

pages

488-93

issue

3

eissn

0147-6513

issn

1090-2414

pii

S0147-6513(04)00257-X

journal_volume

63

pub_type

杂志文章

相关文献

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY文献大全
  • Specific detection of membrane-toxic substances with a conductivity assay.

    abstract：:A conductivity assay that represents a new biotest able to detect the effects of membrane-toxic compounds, e.g., detergents, organic solvents, and radical formers, on various organisms was previously described and developed. The conductivity assay measures ion leakage from cells, tissues, or whole plant and animal org...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1006/eesa.1999.1854

    authors： Eich J,Dürholt H,Steger-Hartmann T,Wagner E

    更新日期：2000-03-01 00:00:00

  • Effect of chiral differences of metolachlor and its (S)-isomer on their toxicity to earthworms.

    abstract：:The effects of (Rac)-metolachlor and (S)-metolachlor on the avoidance behavior, bodyweight change and in vivo enzyme activity of earthworms (Eisenia foetida) were determined and compared in this study. The effects of (Rac)-metolachlor on the enzyme activities of E. foetida and bodyweight were more significant than tho...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2010.07.035

    authors： Xu D,Wen Y,Wang K

    更新日期：2010-11-01 00:00:00

  • Dissipation and residue of dimethomorph in pepper and soil under field conditions.

    abstract：:The dissipation and residual levels of dimethomorph in pepper and soil under field conditions were determined by gas chromatography with an electron capture detector (GC-ECD). The dissipation rates of dimethomorph were described using first-order kinetics and its half-life ranged from 1.7 to 3.8 days in pepper and 11....

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2011.02.009

    authors： Liang H,Li L,Li W,Wu Y,Zhou Z,Liu F

    更新日期：2011-07-01 00:00:00

  • Kinetics of the uptake of 14C-labeled chlorinated benzenes from soil by plants.

    abstract：:[14C]Benzene, [14C]1,2,4-trichlorobenzene, [14C]pentachlorobenzene, and [14C]hexachlorobenzene were applied to soils in outdoor lysimeters to a 10-cm depth (2 mg/kg dry soil); barley and cress plants were grown for one vegetation period and analyzed after varying time intervals. The bioaccumulation factors (concentrat...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/0147-6513(89)90034-1

    authors： Topp E,Scheunert I,Korte F

    更新日期：1989-04-01 00:00:00

  • Biodegradation of atrazine by the novel Citricoccus sp. strain TT3.

    abstract：:A previously undescribed atrazine-degrading bacterial strain TT3 capable of growing with atrazine as its sole nitrogen source was isolated from soil at the wastewater outfall of a pesticide factory in China. Phenotypic characterization and 16S rRNA gene sequencing indicated that the isolate belonged to the genus Citri...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2017.08.046

    authors： Yang X,Wei H,Zhu C,Geng B

    更新日期：2018-01-01 00:00:00

  • Assessing off-target cytotoxicity of the field lampricide 3-trifluoromethyl-4-nitrophenol using novel lake sturgeon cell lines.

    abstract：:Lampricides are currently being applied to streams and rivers to control the population of sea lamprey, an invasive species, in the Great Lakes. The most commonly used lampricide agent used in the field is 3-trifluoromethyl-4-nitrophenol (TFM), which targets larval sea lamprey in lamprey-infested rivers and streams. T...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2018.07.017

    authors： Vo NTK,Moore LC,Spiteri KW,Hanner R,Wilkie MP,DeWitte-Orr SJ

    更新日期：2018-10-30 00:00:00

  • DNA double-strand breaks in relation to persistent organic pollutants in a fasting seabird.

    abstract：:Lipophilic persistent organic pollutants (POPs) are released from fat reserves during fasting, causing increased blood concentrations. Thus, POPs represent a potential anthropogenic stressor during fasting periods. We analysed the blood of female common eiders (Somateria mollissima) by using agarose gel electrophoresi...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2014.04.020

    authors： Fenstad AA,Jenssen BM,Moe B,Hanssen SA,Bingham C,Herzke D,Bustnes JO,Krøkje A

    更新日期：2014-08-01 00:00:00

  • Effects of erythromycin, trimethoprim and clindamycin on attached microbial communities from an effluent dominated prairie stream.

    abstract：UNLABELLED:In this study, differing metrics were utilized to measure effects of erythromycin (ER), trimethoprim (TR) and clindamycin (CL) on the structure and function of attached Wascana Creek, SK microbial communities. All three test antibiotics, especially ER, affected community structure and function of biofilms gr...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2016.05.026

    authors： Waiser MJ,Swerhone GD,Roy J,Tumber V,Lawrence JR

    更新日期：2016-10-01 00:00:00

  • Arbuscular mycorrhiza augments cadmium tolerance in soybean by altering accumulation and partitioning of nutrient elements, and related gene expression.

    abstract：:Arbuscular mycorrhizal (AM) fungi can protect plants against cadmium (Cd) stress, and are the most prominent symbiotic fungi for contribution to phytoremediation. However, the tolerance mechanism for AM symbiosis on Cd toxicity still remains unclear, especially the related molecular mechanisms. In this study, differen...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2018.12.093

    authors： Cui G,Ai S,Chen K,Wang X

    更新日期：2019-04-30 00:00:00

  • Evaluation of a rodent peroxisome proliferator in two species of freshwater fish: rainbow trout (Onchorynchus mykiss) and Japanese medaka (Oryzias latipes)

    abstract：:Rainbow trout (Onchorynchus mykiss) and Japanese medaka (Oryzias latipes) were exposed to the hypolipidemic drug gemfibrozil, a known rodent peroxisome proliferator. Trout were injected (i.p.) daily for 2 weeks at doses of 0, 46, 87, or 152 mg/kg/day. Medaka were exposed to the nominal concentrations of 0, 1.25, 2.5, ...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/0147-6513(94)90026-4

    authors： Scarano LJ,Calabrese EJ,Kostecki PT,Baldwin LA,Leonard DA

    更新日期：1994-10-01 00:00:00

  • A systems-level approach for investigating organophosphorus pesticide toxicity.

    abstract：:The full understanding of the single and joint toxicity of a variety of organophosphorus (OP) pesticides is still unavailable, because of the extreme complex mechanism of action. This study established a systems-level approach based on systems toxicology to investigate OP pesticide toxicity by incorporating ADME/T pro...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2017.10.066

    authors： Zhu J,Wang J,Ding Y,Liu B,Xiao W

    更新日期：2018-03-01 00:00:00

  • Comparative investigation of behavioral, neurotoxicological, and immunotoxicological indices in detection of subacute combined exposure with methyl parathion and propoxur in rats.

    abstract：:The effects of 6 weeks of oral exposure to propoxur (PR; at doses of 0.851 and 8.51 mg/kg body wt.), methylparathion (MP; at doses of 0.218 and 0.872 mg/kg body wt.), and their combinations were investigated in male Wistar rats. Measurement endpoints of the investigation were certain general toxicological parameters (...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/S0147-6513(03)00101-5

    authors： Institoris L,Papp A,Siroki O,Banerjee BD

    更新日期：2004-03-01 00:00:00

  • Joint effects of dietary cadmium and polychlorinated biphenyls on metallothionein induction, lipid peroxidation and histopathology in the kidneys and liver of bank voles.

    abstract：:Free-living bank voles have been shown to be more sensitive to cadmium (Cd) toxicity than the rodents exposed to Cd under laboratory conditions. The present study was designed to find out whether polychlorinated biphenyls (PCBs), common environmental co-contaminants, increase susceptibility to Cd toxicity through inhi...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2007.03.014

    authors： Włostowski T,Krasowska A,Bonda E

    更新日期：2008-03-01 00:00:00

  • Brassinosteroids induce plant tolerance against phenanthrene by enhancing degradation and detoxification in Solanum lycopersicum L.

    abstract：:Polycyclic aromatic hydrocarbons (PAHs) are toxic to both plants and animals. The enhancement of plant tolerance and detoxification capacity is important for the plant-based remediation of PAHs. Therefore, we investigated the effects of 24-epibrassinolide (EBR) on the metabolism of a three-ringed PAH (phenanthrene-PHE...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2012.02.004

    authors： Ahammed GJ,Gao CJ,Ogweno JO,Zhou YH,Xia XJ,Mao WH,Shi K,Yu JQ

    更新日期：2012-06-01 00:00:00

  • A novel computational solution to the health risk assessment of air pollution via joint toxicity prediction: A case study on selected PAH binary mixtures in particulate matters.

    abstract：:Regional haze episode has already caused overwhelming public concern. Unraveling the health effects of the representative composition mixtures of atmospheric fine particulate matters (PM2.5) becomes a top priority. In this study, a novel computational solution integrating chemical-induced genomic residual effect predi...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2018.12.010

    authors： Liu X,Zhang H,Pan W,Xue Q,Fu J,Liu G,Zheng M,Zhang A

    更新日期：2019-04-15 00:00:00

  • Biosorption of Cd(II) from aqueous solution using xanthated nano banana cellulose: equilibrium and kinetic studies.

    abstract：:Present study explored the biosorption capacity of xanthated nano banana cellulose (XNBC) for Cd(II) from aqueous solution. The biosorbent containing sulfur-bearing groups have a high affinity for heavy metals. Sulfur can be considered as a soft ligand group having strong affinity for cadmium. In the present study, th...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2013.09.003

    authors： Pillai SS,Deepa B,Abraham E,Girija N,Geetha P,Jacob L,Koshy M

    更新日期：2013-12-01 00:00:00

  • Directly repurposing waste optical discs with prefabricated nanogrooves as a platform for investigation of cell-substrate interactions and guiding neuronal growth.

    abstract：:Due to rapid change in information technology, many consumer electronics become electronic waste which is the fastest-growing pollution problems worldwide. In fact, many discarded electronics with prefabricated micro/nanostructures may provide a good basis to fulfill special needs of other fields, such as tissue engin...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2018.05.067

    authors： Lu JY,Zhu QY,Zhang XX,Zhang FR,Huang WT,Ding XZ,Xia LQ,Luo HQ,Li NB

    更新日期：2018-09-30 00:00:00

  • Effects of contaminated sediment from Cork Harbour, Ireland on the cytochrome P450 system of turbot.

    abstract：:Hatchery-reared juvenile turbot (Scophthalmus maximus L.) were exposed for 3 weeks, under laboratory conditions, to inter-tidal sediments collected from polluted sites in Cork Harbour (Whitegate and Agahda) and a reference site at Ballymacoda Co., Cork, Ireland. The potential of the sediment exposure to induce cytochr...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2008.09.026

    authors： Kilemade M,Hartl MG,O'Halloran J,O'Brien NM,Sheehan D,Mothersill C,van Pelt FN

    更新日期：2009-03-01 00:00:00

  • Characteristic of adsorption, desorption, and co-transport of vanadium on humic acid colloid.

    abstract：:Understanding the interactions between humic acid colloid (HAC) and vanadium (V) in soils is of great importance in forecasting the behaviors and fates of V in the soil and groundwater systems. This study investigated the characteristics and factors that affect V adsorption-desorption by the HAC; meanwhile, we also ex...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2019.110087

    authors： Chen L,Zhu YY,Luo HQ,Yang JY

    更新日期：2020-03-01 00:00:00

  • Terrestrial microcosms in a feasibility study on the remediation of diesel-contaminated soils.

    abstract：:Phytoremediation and bioremediation are site-specific processes, and feasibility studies should be performed as an initial step in scaling-up these processes. Soil microcosms can be a useful tool for investigating the efficiency of remediation alternatives under realistic conditions. In the present study, the degradat...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2011.08.009

    authors： Fernández MD,Pro J,Alonso C,Aragonese P,Tarazona JV

    更新日期：2011-11-01 00:00:00

  • Acute effects of cadmium and copper on survival, oxygen consumption, ammonia-N excretion, and metal accumulation in juvenile Exopalaemon carinicauda.

    abstract：:Ridgetail white prawn (Exopalaemon carinicauda), a commercially important species in China, is a potential candidate for evaluating impairments caused by environmental pollutants in coastal and estuarine areas. The main purpose of the present study was to investigate the acute effects of cadmium (Cd) and copper (Cu) o...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2014.01.008

    authors： Zhang C,Li F,Xiang J

    更新日期：2014-06-01 00:00:00

  • Bioaccumulation of mercury in various fish species from Orlík and Kamýk water reservoirs in the Czech Republic.

    abstract：:The study evaluated contamination of fish by mercury in two important Czech water reservoirs, Orlík and Kamýk, which receive water from the whole watershed of Otava and Vltava rivers. Contamination of these reservoirs reflects the situation in southern and western Bohemia. Six environmentally representative sites were...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1006/eesa.1999.1783

    authors： Svobodová Z,Dusek L,Hejtmánek M,Vykusová B,Smíd R

    更新日期：1999-07-01 00:00:00

  • Comparative ecotoxicity of polystyrene nanoparticles in natural seawater and reconstituted seawater using the rotifer Brachionus plicatilis.

    abstract：:The impact of nanoplastics using model polystyrene nanoparticles (PS NPs), anionic (PS-COOH) and cationic (PS-NH2), has been investigated on the marine rotifer Brachionus plicatilis, a major component of marine zooplanktonic species. The role of different surface charges in affecting PS NP behaviour and toxicity has b...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2017.07.068

    authors： Manfra L,Rotini A,Bergami E,Grassi G,Faleri C,Corsi I

    更新日期：2017-11-01 00:00:00

  • Toxicity of nonylphenol and nonylphenol ethoxylate on Caenorhabditis elegans.

    abstract：:Among the most used chemicals in the world are nonionic surfactants. One of these environmental pollutants is nonylphenol ethoxylate (NP-9), also known as Tergitol, and its degradation product, nonylphenol (NP). The objective of this work was to determine the toxicity of NP and NP-9 in Caenorhabditis elegans. Wild-typ...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2019.109709

    authors： De la Parra-Guerra A,Olivero-Verbel J

    更新日期：2020-01-15 00:00:00

  • Kinetics studies on the removal of Methyl ethyl ketone using cornstack based biofilter.

    abstract：:The performance of cornstack based biofilter inoculated with a mixed culture was evaluated for gas phase MEK removal under various operating conditions. Experiments were carried out at different flow rates (0.03-0.12m3h-1) and various initial concentrations (0.2-1.2g-3). A maximum elimination capacity (EC) of 35g-3h-1...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2015.09.016

    authors： Ashokkumar S,Nair AS,Saravanan V,Rajasimman M,Rajamohan N

    更新日期：2016-12-01 00:00:00

  • Acute toxic effects of zinc and mercury on survival, standard metabolism, and metal accumulation in juvenile ridgetail white prawn, Exopalaemon carinicauda.

    abstract：:Ridgetail white prawn (Exopalaemon carinicauda) is widely distributed in Chinese coastal zones, especially in the Yellow Sea and Bohai Sea. It is not only considered as an important economic species in China, but also taken as a potential indicator species for the environmental pollution in the estuaries. At present, ...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2017.07.075

    authors： Zhang C,Yu K,Li F,Xiang J

    更新日期：2017-11-01 00:00:00

  • Cell density dependence of Microcystis aeruginosa responses to copper algaecide concentrations: Implications for microcystin-LR release.

    abstract：:Along with mechanistic models, predictions of exposure-response relationships for copper are often derived from laboratory toxicity experiments with standardized experimental exposures and conditions. For predictions of copper toxicity to algae, cell density is a critical factor often overlooked. For pulse exposures o...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2017.08.010

    authors： Kinley CM,Iwinski KJ,Hendrikse M,Geer TD,Rodgers JH Jr

    更新日期：2017-11-01 00:00:00

  • Nonylphenol biodegradation in river sediment and associated shifts in community structures of bacteria and ammonia-oxidizing microorganisms.

    abstract：:Nonylphenol (NP) is one of commonly detected contaminants in the environment. Biological degradation is mainly responsible for remediation of NP-contaminated site. Knowledge about the structure of NP-degrading microbial community is still very limited. Microcosms were constructed to investigate the structure of microb...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2014.04.019

    authors： Wang Z,Yang Y,Sun W,Xie S,Liu Y

    更新日期：2014-08-01 00:00:00

  • Winter third- to fourth-instar larvae of Chironomus plumosus as bioassay tools for assessment of acute toxicity of metals and their binary combinations.

    abstract：:The ecotoxicological effect expressed as mortality of four metal ions (Cd, Cu, Zn, Al) and their associations on winter third- to fourth-instar larvae of Chironomus plumosus was determined. The effect of individual metals was introduced as acute toxicological effect and expressed as LC(50) and LC95 values with 95% int...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1006/eesa.2000.1980

    authors： Fargasová A

    更新日期：2001-01-01 00:00:00

  • Impact of 17alpha-ethinylestradiol on the plankton in freshwater microcosms--II: responses of phytoplankton and the interrelation within the ecosystem.

    abstract：:Effects of 17alpha-ethinylestradiol (EE) on phytoplankton were investigated in a lentic freshwater microcosm study. Treatment with EE caused a shift in the species composition as shown by a principle response curve. Whereas densities of Cyanophyceae, Dinophyceae, and Chrysophyceae increased, those of Conjugatophyceae ...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2007.01.014

    authors： Hense BA,Jaser W,Welzl G,Pfister G,Wöhler-Moorhoff GF,Schramm KW

    更新日期：2008-03-01 00:00:00