Abstract:
RATIONALE AND OBJECTIVES:To investigate the relationship between apparent diffusion coefficient (ADC) values and the Ki-67 staining index (Ki-67 SI), a tumor proliferation marker, in prostate cancer (PCa). MATERIALS AND METHODS:Forty-three patients with PCa and thirty-six patients with benign prostatic hyperplasia (BPH) underwent diffusion-weighted (DW) imaging on 3T magnetic resonance (MR) with pelvic phased-array coil. The ADC values of PCa were calculated from two DW images (b = 0, 800 s/mm(2)). Immunohistochemical staining for Ki-67 was used to determine the Ki-67 SI of PCa and BPH. The Pearson correlation test was used to examine the relationship between ADC values and the Ki-67 SI. The ADC values of PCa with different level of Ki-67 SI were compared using an independent-sample t-test. RESULTS:The mean (±standard deviation [SD]) Ki-67 SI of PCa (7.23 ± 5.29%) was higher than that of BPH (2.11 ± 1.90%) (P < .001). The mean (±SD) ADC value (10(-3) mm(2)/s) of PCa (0.850 ± 0.155) was lower than that of BPH (1.173 ± 0.245) (P < .001). The ADC values of PCa were negatively correlated with the Ki-67 SI (r = -0.459, P = .002). The mean ADC values of PCa with Ki-67 >3.5% and ≤3.5% were (0.803 ± 0.094) and (0.936 ± 0.208), respectively. The former was significantly lower than the latter (P = .031). The ADC values of PCa with Ki-67 >7.1% and ≤7.1% were (0.779 ± 0.081) and (0.906 ± 0.178), respectively. The difference was significant (P = .004). CONCLUSION:The ADC values of PCa could reflect the tumor proliferative activity and the differentiated degree of PCa.
journal_name
Acad Radioljournal_title
Academic radiologyauthors
Zhang J,Jing H,Han X,Huang Z,Cao Z,Liu Qdoi
10.1016/j.acra.2013.09.007subject
Has Abstractpub_date
2013-12-01 00:00:00pages
1535-41issue
12eissn
1076-6332issn
1878-4046pii
S1076-6332(13)00415-7journal_volume
20pub_type
杂志文章abstract:RATIONALE AND OBJECTIVES:The aim of this study was to determine the optimal arterial phase delay for computed tomography imaging of hepatocellular carcinoma (HCC) before and after transarterial chemoembolization (TACE) using a low iodine dose protocol. MATERIALS AND METHODS:A total of 39 patients with known HCC were i...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2015.08.021
更新日期:2015-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The objective of this study was to develop and validate a predictive magnetic resonance imaging (MRI) activity score for ileocolonic Crohn disease activity based on both subjective and semiautomatic MRI features. MATERIALS AND METHODS:An MRI activity score (the "virtual gastrointestinal tract ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2017.12.024
更新日期:2018-08-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors performed this study to (a) measure changes in T2 relaxation rates, signal-to-noise ratio (SNR), and contrast with sequential depletion of proteoglycan in cartilage; (b) determine whether there is a relationship between the T2 relaxation rate and proteoglycan in cartilage; and (c) c...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)80666-9
更新日期:2002-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Digitizing images for use in case presentations based on hardcopy films, slides, photographs, negatives, books, and videos can present a challenging task. Scanners and digital cameras have become standard tools of the trade. Unfortunately, use of these devices to digitize multiple images in man...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)00010-2
更新日期:2003-08-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:A method is presented to track guide wires during endovascular interventions under X-ray fluoroscopy. Accurate guide wire tracking can be used to improve guide wire visualization in the low quality fluoroscopic images, and to estimate the position of the guide wire in world coordinates for navi...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)00539-7
更新日期:2003-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Lymphangiomatosis is a rare disease characterized by the widespread presence of lymphangiomas in any part of the body. In previous studies, lymphatic vessel abnormalities in lymphangiomatosis have only rarely been mentioned. The objective of this paper is to discuss the imaging features of lymp...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2019.03.024
更新日期:2020-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The purpose of our study is to perform an internal validation of a new reference standard for vasospasm diagnosis in aneurysmal subarachnoid hemorrhage (A-SAH) patients. MATERIALS AND METHODS:A retrospective study was performed on A-SAH patients between January 2002 and May 2009. All patients ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2010.04.025
更新日期:2010-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of the study is to develop a permutation test to compare receiver operating characteristic (ROC) curves of two diagnostic modalities in a multireader paired design. MATERIALS AND METHODS:A statistical test for comparing two diagnostic modalities is developed based on all possible excha...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2005.12.012
更新日期:2006-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of this study was to prospectively examine the impact of a tablet-based curriculum on the radiology resident educational experience. MATERIALS AND METHODS:A comprehensive tablet-based curriculum was developed by creating subspecialty modules with appropriate content level for each requ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2018.05.018
更新日期:2018-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Pathogenic mutations in some genes elevate women's breast cancer risk, necessitating risk-reduction strategies. Unfortunately, women are underscreened for cancer risk, and when identified as potentially high risk, women seldom pursue genetic counseling or testing. To improve cancer risk managem...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.12.005
更新日期:2020-12-15 00:00:00
abstract:RATIONALE AND OBJECTIVES:Prospective studies of radiologists' interpretations of selected radiographs reported 20-40 years ago indicated error rates of 30% and higher. The authors retrospectively evaluated the interpretations of groups of radiologists and determined a range of rates of disagreement in interpretation. Q...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(98)80277-8
更新日期:1998-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To investigate residents' knowledge of adverse effects of ionizing radiation, frequency of their education on radiation safety, and their use of radioprotective equipment. MATERIALS AND METHODS:Residents from 15/16 residency programs at Emory University were asked to complete a resident radiat...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2014.01.016
更新日期:2014-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The purpose of this study was to evaluate residents' use of a radiology curriculum CD-ROM designed to provide ready access to the department's curricula, study materials, and Internet resources. MATERIALS AND METHODS:A survey questionnaire eliciting feedback about the usability and value of th...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)80085-5
更新日期:2003-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Great expertise is necessary to mentally compile a series of individual two-dimensional image sections into a three-dimensional (3D) composite view that can aid in differential diagnosis. The purpose of this study was to test 3D volume-rendering techniques for differentiating congenital cystic ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)80108-3
更新日期:2003-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To investigate the feasibility of oxygen-challenge blood oxygen level-dependent (BOLD) magnetic resonance imaging (MRI) at 3T for evaluating the early change of blood oxygenation before and after transcatheter arterial embolization (TACE) in patients with hepatocellular carcinoma (HCC). MATERI...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.06.021
更新日期:2020-07-31 00:00:00
abstract:PURPOSE:This investigation is part of a prospective National Institutes of Health-funded study evaluating three different methods for estimating the optimal length for placement of a new nasogastric (NG) tube. Abdomen radiographs were required to determine the location of the tube tip. Our objective was to analyze diff...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2012.02.007
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:To evaluate diagnostic accuracy and clinical outcomes of patients with porcelain gallbladder (GB) diagnosed on CT. MATERIALS AND METHODS:In this IRB-approved, HIPAA-compliant study, consecutive patients with porcelain gallbladder reported on CT between December 1, 2000 and August 31, 2017 in a tertiary academi...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.07.006
更新日期:2020-08-04 00:00:00
abstract:RATIONALE AND OBJECTIVES:HER-2/neu is a valuable prognostic and therapeutic marker in primary breast carcinoma. The objective of this study was to determine the mammographic and patient characteristics (age) that correlate with HER-2/neu overexpression in primary breast carcinoma. MATERIALS AND METHODS:HER-2/neu chara...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2006.06.015
更新日期:2006-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The purpose of this study was to investigate the potential effects of patient size and radiation dose on the accuracy of iodine quantification using dual-source dual-energy computed tomography (CT). MATERIALS AND METHODS:Three phantoms representing different patient sizes were constructed, con...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2019.12.027
更新日期:2021-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The goal of this prospective, interinstitutional study was to compare the long-term instructional effectiveness of a pediatric multimedia textbook (MMTB) to that of a standard lecture and a printed textbook. MATERIALS AND METHODS:A randomized cohort of 89 3rd-year medical students from two ins...
journal_title:Academic radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s1076-6332(97)80074-8
更新日期:1997-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of this study was to develop a pulmonary nodule viewing system to visualize and retrieve data from the Lung Image Database Consortium. MATERIALS AND METHODS:The pulmonary nodule viewing system, developed using Microsoft C++ and the .NET 2.0 Framework, is composed of a clinical informat...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2011.04.006
更新日期:2011-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The purpose of this study was to test the effectiveness of resident-prepared, independent learning cases in teaching residents chest radiology. MATERIALS AND METHODS:Three 2nd-year residents (one each from the University of Wisconsin, the Oregon Health Sciences University, and the University o...
journal_title:Academic radiology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s1076-6332(99)80059-2
更新日期:1999-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors performed this study to compare magnetic resonance (MR) venography and conventional venography in the diagnosis of deep venous thrombosis (DVT) in the calf after sonography. MATERIALS AND METHODS:Sonography was performed in 595 patients who were suspected of having lower-extremity ...
journal_title:Academic radiology
pub_type: 临床试验,杂志文章
doi:10.1016/s1076-6332(03)80764-x
更新日期:2001-09-01 00:00:00
abstract::The National Cancer Institute organized a workshop entitled "Image Archive Management" that was presented on August 28 and 29, 2000, at the Natcher Conference Center on the National Institutes of Health (NIH) campus. The purpose of this workshop was to solicit expert input for the planned development of an archival sy...
journal_title:Academic radiology
pub_type:
doi:10.1016/S1076-6332(03)80699-2
更新日期:2001-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The capability of wavelet transforms to separate signals into frequency bands is the basis for its use in image compression and storage, data management and transmission, and, recently, extraction of latent images of tissue components from noisy medical images. Analysis of temporal variations o...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2007.06.018
更新日期:2007-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To retrospectively analyze the significance of 3.0-T contrast-enhanced (CE) magnetic resonance angiography (MRA) with calf compression in the lower limbs of diabetic patients with peripheral vascular disease. MATERIALS AND METHODS:Sixty-one type 2 diabetes patients underwent both MRA and digit...
journal_title:Academic radiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.acra.2011.01.013
更新日期:2011-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study aimed to determine whether mammographic features assessed by radiologists and using computer algorithms are prognostic of occult invasive disease for patients showing ductal carcinoma in situ (DCIS) only in core biopsy. MATERIALS AND METHODS:In this retrospective study, we analyzed ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2017.03.013
更新日期:2017-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Obscure gastrointestinal bleeding (OGIB) is the bleeding from the gastrointestinal tract without definite source that persists and recurs after a negative endoscopic evaluation. The study aimed to systematically evaluate the diagnostic accuracy of computed tomography enterography on OGIB detect...
journal_title:Academic radiology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.acra.2017.09.001
更新日期:2018-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Extraprostatic extension of disease (EPE) has a major role in risk stratification of prostate cancer patients. Currently, pretreatment local staging is performed with MRI, while the gold standard is represented by histopathological analysis after radical prostatectomy. Texture analysis (TA) is ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2018.12.025
更新日期:2019-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Designed to provide broad-based training in all aspects of imaging, the diagnostic radiology residency program must provide educational experiences that not only provide technical training, but also meet accreditation standards. With the breadth of material to cover during training, carefully o...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.12.022
更新日期:2021-01-21 00:00:00