当前位置： SCI文献检索 > JOURNAL OF ETHNOPHARMACOLOGY期刊下所有文献 > Berberine improves neurogenic contractile response of bladder detrusor muscle in streptozotocin-induced diabetic rats.

Berberine improves neurogenic contractile response of bladder detrusor muscle in streptozotocin-induced diabetic rats.

Abstract：

ETHNOPHARMACOLOGICAL RELEVANCE:Coptidis Rhizoma has been used to treat diabetes mellitus for more than 1400 years in China. Berberine, one of the main alkaloids of Coptidis Rhizoma, is a principal antidiabetic component of Coptidis Rhizoma. To investigate the effects of berberine on impaired neurogenic contractility of detrusor muscle from urinary bladder of rats with early stage diabetes. MATERIALS AND METHODS:The detrusor muscle strips were isolated from urinary bladders of streptozotocin-induced diabetic rats, 5% sucrose-induced diuretic rats or normal rats, and were placed in organ bath. The contractions induced by electrical field stimulation (EFS), carbachol, KCl, adenosine triphosphate, and the effects of berberine on those contractions were measured. RESULTS:The EFS- or KCl-induced contraction of detrusor muscle was significantly decreased in diabetic rats as compared with diuretic or normal rats. Atropine and suramin inhibited EFS-induced contraction. In diabetic rats, the atropine sensitive components were decreased in EFS-induced contraction of detrusor muscle, and the adenosine triphosphate-induced contraction was significantly increased. The carbachol-induced contrations were not different among groups. Berberine significantly potentiated EFS-induced contractions of detrusor muscle both from normal and diabetic rats, but the potentiated effect of BBR was more sensitive to atropine in diabetic rats. Berberine also potentiated adenosine triphosphate-induced contraction of detrusor muscle, but did not change carbachol- or KCl-induced contraction. CONCLUSION:The neurogenic contraction of urinary bladder detrusor muscle is decreased while purinergic contraction of bladder detrusor muscle is increased in rats with early stage diabetes. Berberine increases the neurogenic contractile response to EFS possibly via both presynaptic increasing neurotransmitters release and postsynaptic potentiation of purinergic transmitter-regulated response in rat urinary bladder detrusor; and in diabetic rats, berberine increases neurogenic contractile response mainly via the presynaptic increasing acetylcholine release.

journal_name

J Ethnopharmacol

journal_title

Journal of ethnopharmacology

authors

Ren LM,Zhuo YJ,Hao ZS,He HM,Lu HG,Zhao D

doi

10.1016/j.jep.2013.10.039

subject

Has Abstract

pub_date

2013-12-12 00:00:00

pages

1128-36

issue

3

eissn

0378-8741

issn

1872-7573

pii

S0378-8741(13)00746-0

journal_volume

150

pub_type

杂志文章

相关文献

JOURNAL OF ETHNOPHARMACOLOGY文献大全
  • Antiosteoporotic effect of Hemidesmus indicus Linn. on ovariectomised rats.

    abstract：PHARMACOLOGICAL RELEVANCE:Root of Hemidesmus indicus (L). R. Br., an herbal drug of India is traditionally used to prevent or treat female hormonal disturbance related disorders and assuaging symptoms of menopausal conditions. AIM OF THE STUDY:Lack of scientific data for potential use in bone loss, the present study w...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2017.01.031

    authors： Desai S,Babaria P,Nakarani M,Shah K,Paranjape A

    更新日期：2017-03-06 00:00:00

  • 5α-reductase inhibition and hair growth promotion of some Thai plants traditionally used for hair treatment.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Many Thai traditional herbs have been used for hundreds of years for hair treatment and nourishment, including hair loss. However, scientific evidence about their mechanisms of action has not yet been elucidated. AIMS OF THE STUDY:The purpose of this research is to define the possible me...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2011.12.010

    authors： Kumar N,Rungseevijitprapa W,Narkkhong NA,Suttajit M,Chaiyasut C

    更新日期：2012-02-15 00:00:00

  • Antidepressant-like effects of Xiaochaihutang in perimenopausal mice.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Xiaochaihutang (XCHT) is a traditional Chinese medicine prescription for thousand years in China. Our previous researches show that XCHT has antidepressant-like effects in several depression models, but effect and mechanism of XCHT in perimenopausal depression are still vague. AIM OF THE...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2019.112318

    authors： Zhang K,Wang Z,Pan X,Yang J,Wu C

    更新日期：2020-02-10 00:00:00

  • The water expelling effect evaluation of 3-O-(2'E,4'Z-decadienoyl)-20-O-acetylingenol and ingenol on H22 mouse hepatoma ascites model and their content differences analysis in Euphorbia kansui before and after stir-fried with vinegar by UPLC.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Malignant ascites (MA) effusion is mainly caused by hepatocellular, ovarian, and breast cancer etc. It has been reported that Euphorbia kansui (EK), the root of Euphorbia kansui S.L.Liou ex S.B.Ho, possessing a therapeutic effect on MA. However, the clinical applications of EK are serious...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.113507

    authors： Zhang Q,Ju YH,Zhang Y,Wang K,Zhang M,Chen PD,Yao WF,Tang YP,Wu JH,Zhang L

    更新日期：2021-03-01 00:00:00

  • Comparative antimicrobial study of the resinous exudates of some Chilean Haplopappus (Asteraceae).

    abstract：:The antimicrobiol properties and preliminary chemical information of the resinous exudates from twigs and leaves of nine Haplopappus species from Chile: H. diplopappus; H. anthylloides; H. schumannii; H. cuneifolius; H. velutinus; H. uncinatus; H. multifolius, H. illinitus and H. foliosus are presented. The results sh...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/0378-8741(94)01196-7

    authors： Urzúa A,Torres R,Muñoz M,Palacios Y

    更新日期：1995-01-01 00:00:00

  • β-carboline alkaloids attenuate bleomycin induced pulmonary fibrosis in mice through inhibiting NF-kb/p65 phosphorylation and epithelial-mesenchymal transition.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The plant Arenaria kansuensis is used in traditional medicine to treat lung inflammation for a long time. However, the anti-pulmonary fibrosis effect and its corresponding bioactive constituents of this plant have not been studied extensively. AIM OF THE STUDY:The purpose of this study w...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2019.112096

    authors： Cui Y,Jiang L,Yu R,Shao Y,Mei L,Tao Y

    更新日期：2019-10-28 00:00:00

  • Comprehensive evaluation on anti-inflammatory and anti-angiogenic activities in vitro of fourteen flavonoids from Daphne Genkwa based on the combination of efficacy coefficient method and principal component analysis.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Genkwa flos, as a traditional herb, is the dried flower buds of Daphne genkwa Sieb.et Zucc. It is used in traditional medicine for the treatment of cough, sore throats, edema. AIM OF THE STUDY:The study aimed to explore a new mathematical method for multivariate evaluation, investigate t...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.113683

    authors： Zhou DC,Zheng G,Jia LY,He X,Zhang CF,Wang CZ,Yuan CS

    更新日期：2021-03-25 00:00:00

  • Antidepressant-like effect of the extracted of Kai Xin San, a traditional Chinese herbal prescription, is explained by modulation of the central monoaminergic neurotransmitter system in mouse.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Kai Xin San (KXS) is a traditional Chinese herbal prescription for the treatment of depression-like disorders, anxiety, and impairment in learning and memory, however, there is very little scientific data concerning the efficacy of this. AIM OF THE STUDY:The present study aimed to invest...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2011.11.027

    authors： Zhou XJ,Liu M,Yan JJ,Cao Y,Liu P

    更新日期：2012-01-31 00:00:00

  • Genotoxicity of Brosimum gaudichaudii measured by the Salmonella/microsome assay and chromosomal aberrations in CHO cells.

    abstract：:The root bark of Brosimum gaudichaudii Trécul (Moraceae) is popularly used for treatment of vitiligo. In the present study the mutagenic activity of the aqueous and methanolic extract as well as of the n-butanolic fraction of this medicinal plant were evaluated using Salmonella typhimurium assays, TA100, TA98, TA102 a...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(02)00089-2

    authors： Varanda EA,Pozetti GL,Lourenço MV,Vilegas W,Raddi MS

    更新日期：2002-07-01 00:00:00

  • Neuropharmacological screening of Diospyros mespiliformis in mice.

    abstract：:The neuropharmacological activities of the aqueous extract of Diospyros mespiliformis stem bark were screened in mice. The extracts effect on pentobarbital-induced sleeping time, pentylenetetrazole induced seizure, spontaneous motor activity (SMA), exploratory behaviour, and rota-rod performance (motor coordination) w...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(02)00249-0

    authors： Adzu B,Amos S,Muazzam I,Inyang US,Gamaniel KS

    更新日期：2002-11-01 00:00:00

  • Evaluation of potential herb-drug interactions between oseltamivir and commonly used anti-influenza Chinese medicinal herbs.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:According to Traditional Chinese Medicine theory, influenza is categorized as a warm disease or Wen Bing. The Wen Bing formulas, such as Yin-Qiao-San and Sang-Ju-Yin, are still first-line herbal therapies in combating variant influenza virus. To continue our study on the pharmacokinetic a...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2019.112097

    authors： Zhang Y,Lyu C,Fong SYK,Wang Q,Li C,Ho NJ,Chan KS,Yan X,Zuo Z

    更新日期：2019-10-28 00:00:00

  • A Review of the Phytochemical, Pharmacological, Pharmacokinetic, and Toxicological Evaluation of Quercus Infectoria Galls.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Quercus Infectoria galls (QIG) have a long history of use in traditional Chinese medicine and traditional Uyghur medicine for the treatment of diarrhea, hemorrhage, skin disease, and many other human ailments. Medicinal applications of QIG have become increasingly popular in Greece, Asia ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2020.113592

    authors： Elham A,Arken M,Kalimanjan G,Arkin A,Iminjan M

    更新日期：2020-11-17 00:00:00

  • Antidiarrhoeal activity of Waltheria americana, Commelina coelestis and Alternanthera repens.

    abstract：:The antidiarrhoeal activity of the hexane, chloroform, methanol and aqueous extracts of Waltheria americana, Commelina coelestis and Alternathera repens, was tested on mice with diarrhoea induced by castor oil and MgSO4. The methanol extract of C. coelestis and A. repens and aqueous extract of A. repens, presented ant...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(98)00014-2

    authors： Zavala MA,Pérez S,Pérez C,Vargas R,Pérez RM

    更新日期：1998-05-01 00:00:00

  • Antiinflammatory activity of a Ghanaian antiarthritic herbal preparation: II.

    abstract：:A boiling water extract from a mixture of Alstonia boonei and Rauvolfia vomitoria root barks and Elaeis guineensis nuts without pericarp was tested for its antiinflammatory activity by measuring over a period of 17 days the changes in rat ankle diameter caused by subplantar injection of complete Freund's adjuvant. The...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/0378-8741(91)90171-9

    authors： Kweifio-Okai G

    更新日期：1991-05-01 00:00:00

  • A novel approach using metabolomics coupled with hematological and biochemical parameters to explain the enriching-blood effect and mechanism of unprocessed Angelica sinensis and its 4 kinds of processed products.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Angelica sinensis (AS), root of Angelica sinensis (Oliv.) Diels, an important kind of Chinese traditional herbal medicine, has been used for women to enrich the blood for thousands of years. It is mainly distributed in Gansu province of China. According to Traditional Chinese medicine usa...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2017.09.028

    authors： Ji P,Wei Y,Hua Y,Zhang X,Yao W,Ma Q,Yuan Z,Wen Y,Yang C

    更新日期：2018-01-30 00:00:00

  • Standardized flavonoid-rich fraction of Artemisia princeps Pampanini cv. Sajabal induces apoptosis via mitochondrial pathway in human cervical cancer HeLa cells.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Artemisia princeps Pampanini is widely used in Eastern traditional medicine for the treatment of circulatory disorders, such as, dysmenorrhea, hematuria, hemorrhoids, and inflammation, and is also used to treat chronic conditions, such as, cancers, ulcers, and digestive disorders. AIM OF...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2012.03.011

    authors： Ju HK,Lee HW,Chung KS,Choi JH,Cho JG,Baek NI,Chung HG,Lee KT

    更新日期：2012-05-07 00:00:00

  • Antithrombocytopenic activity of carpaine and alkaloidal extract of Carica papaya Linn. leaves in busulfan induced thrombocytopenic Wistar rats.

    abstract：ETHNOPHARMACOLOGICAL RELAVANCE:The decoction of Carica papaya Linn. leaves is used in folklore medicine in certain parts of Malaysia and Indonesia for the treatment of different types of thrombocytopenia associated with diseases and drugs. There are several scientific studies carried out on humans and animal models to ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2016.01.035

    authors： Zunjar V,Dash RP,Jivrajani M,Trivedi B,Nivsarkar M

    更新日期：2016-04-02 00:00:00

  • Isolation of seselin from Clausena anisata (Rutaceae) leaves and its effects on the feeding and development of Lucilia cuprina larvae may explain its use in ethnoveterinary medicine.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The leaves of Clausena anisata are used traditionally to expel maggots from wounds of animals in Zimbabwe. We have previously proved in the laboratory that the plant certainly affects the behaviour and growth of blowfly larvae. The objective of this study was to isolate and identify the a...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2013.09.037

    authors： Mukandiwa L,Ahmed A,Eloff JN,Naidoo V

    更新日期：2013-12-12 00:00:00

  • Investigation of anti-asthmatic potential of Kanakasava in ovalbumin-induced bronchial asthma and airway inflammation in rats.

    abstract：ETHNO-PHARMACOLOGICAL RELEVANCE:Kanakasava is an Indian traditional Ayurvedic formulation containing Datura (Datura metel), Vasaca (Adhatoda vasica), Dhataki (Woodfordia fruticosa) and Grape (Vitis vinifera) extracts as major constituents and used to treat pulmonary diseases including coughing, breathing difficulty and...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2016.07.082

    authors： Arora P,Ansari SH,Anjum V,Mathur R,Ahmad S

    更新日期：2017-02-02 00:00:00

  • The fruit essential oil of Pimpinella anisum exerts anticonvulsant effects in mice.

    abstract：:This study investigates anticonvulsant effects of an essential oil of the fruits of Pimpinella anisum (Umbelliferae), a folkloric remedy in the Iranian traditional medicine, against seizures induced by pentylenetetrazole (PTZ) or maximal electroshock (MES) in male mice. The essential oil suppressed tonic convulsions i...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(98)00161-5

    authors： Pourgholami MH,Majzoob S,Javadi M,Kamalinejad M,Fanaee GH,Sayyah M

    更新日期：1999-08-01 00:00:00

  • Pharmacological potential and conservation prospect of the genus Eucomis (Hyacinthaceae) endemic to southern Africa.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The genus Eucomis (Hyacinthaceae) consists of 10 species that are extensively used in African traditional medicine. This review is an appraisal of current information on the distribution and morphology, traditional uses, pharmacology, toxicology and approaches devised to enhance the conse...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2013.11.002

    authors： Masondo NA,Finnie JF,Van Staden J

    更新日期：2014-01-01 00:00:00

  • Inhibition of lipopolysaccharide and interferon-gamma-induced expression of inducible nitric oxide synthase and tumor necrosis factor-alpha by Lithospermi radix in mouse peritoneal macrophages.

    abstract：:Lithospermi radix (LR, root of Lithospermum erythrorhizon Siebold. et Zuccarinii) has been used to treat various conditions, such as septic shock, eczema and burns. In this study, the effect of LR on lipopolysaccharide (LPS) and recombinant interferon-gamma (rIFN-gamma)-induced production of nitric oxide (NO) and tumo...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2005.06.028

    authors： Chung HS,Kang M,Cho C,Park S,Kim H,Yoon YS,Kang J,Shin MK,Hong MC,Bae H

    更新日期：2005-12-01 00:00:00

  • A cross-cultural analysis of Jammu, Kashmir and Ladakh (India) medicinal plant use.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Jammu & Kashmir (J&K) is a predominantly Himalayan state in the north-western part of India. It has three geographically distinct divisions viz., Jammu, Kashmir and Ladakh, which are immensely rich in their biological and cultural diversity. Medicinal plants are an important element of in...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2014.06.029

    authors： Gairola S,Sharma J,Bedi YS

    更新日期：2014-09-11 00:00:00

  • The Chinese herbal formulae (Yitangkang) exerts an antidiabetic effect through the regulation of substance metabolism and energy metabolism in type 2 diabetic rats.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Type 2 diabetes mellitus (T2DM) regarded as a "hot" disease in traditional Chinese medicine (TCM). Accordingly, TCM uses a cold drug or formula such as the Chinese herbal formulae "Yitangkang" (YTK) as a treatment. YTK exhibited a good clinical antidiabetic effect in several experiments. ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2019.111942

    authors： Han X,Yang Y,Metwaly AM,Xue Y,Shi Y,Dou D

    更新日期：2019-07-15 00:00:00

  • Extracts and fractions of Thymus capitatus exhibit antimicrobial activities.

    abstract：:Preliminary phytochemical screening of the plant Thymus capitatus exhibited the presence of saponins, resins, flavonoids, essential and fixed oils. Aqueous and ethanolic extracts (10-200 mg/ml) as well as saponin, resin and essential oil of the plant (10-5000 micrograms/ml inhibited the growth of several bacteria and ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/0378-8741(94)90094-9

    authors： Kandil O,Radwan NM,Hassan AB,Amer AM,el-Banna HA,Amer WM

    更新日期：1994-08-01 00:00:00

  • Chinese materia medica used in medicinal diets.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Medicinal diets have a history of more than 2000 years. Locally referred to as yaoshan (Chinese: ), a medicinal diet is understood in China as a dietary product that combines herbs and food with the purpose of preventing and treating diseases or improving health under the guidance of trad...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2017.05.021

    authors： Tan F,Chen Y,Tan X,Ma Y,Peng Y

    更新日期：2017-07-12 00:00:00

  • In vitro antibacterial activities of three plants used in traditional medicine in Sierra Leone.

    abstract：:The antibacterial activities of the methanol and hot and cold aqueous extracts of the leaves of Aspilia africana, Ficus exasperata and Mareya micrantha were bioassayed against three Gram-negative and three Gram-positive bacterial species: Aerobacter aerogenes, Agrobacterium tumefaciens, Bacillus subtilis, Clostridium ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/0378-8741(90)90083-6

    authors： Macfoy CA,Cline EI

    更新日期：1990-03-01 00:00:00

  • Antimicrobial properties of Honduran medicinal plants.

    abstract：:Ninety-two plants used in the traditional pharmacopoeia of the Pech and neighboring Mestizo peoples of central Honduras are reported. The results of in vitro antimicrobial screens showed that 19 of the extracts from medicinal plants revealed signs of antifungal activity while 22 demonstrated a measurable inhibitory ef...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(98)00100-7

    authors： Lentz DL,Clark AM,Hufford CD,Meurer-Grimes B,Passreiter CM,Cordero J,Ibrahimi O,Okunade AL

    更新日期：1998-12-01 00:00:00

  • Evaluation of the toxicity potential of acute and sub-acute exposure to the aqueous root extract of Aristolochia ringens Vahl. (Aristolochiaceae).

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Aristolochia ringens Vahl. (Aristolochiaceae) is used traditionally in Nigeria for managing a number of ailments including gastrointestinal disturbances, rheumatoid arthritis, pile, insomnia, oedema, and snake bite venom. Some studies in our laboratory have demonstrated a scientific justi...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2019.112150

    authors： Aigbe FR,Sofidiya OM,James AB,Sowemimo AA,Akindere OK,Aliu MO,Dosunmu AA,Chijioke MC,Adeyemi OO

    更新日期：2019-11-15 00:00:00

  • Modulation of quorum sensing-controlled virulence factors by Nymphaea tetragona (water lily) extract.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Nymphaea tetragona is a widely distributed ornamental species with ethnomedicinal uses in the treatment of diarrhea, dysentery, eruptive fevers, and infections. The anti-infectious activities of this herb have already been assessed to clarify its traditional use as a medicine. AIM OF STU...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2015.08.049

    authors： Hossain MA,Lee SJ,Park JY,Reza MA,Kim TH,Lee KJ,Suh JW,Park SC

    更新日期：2015-11-04 00:00:00