Abstract:
OBJECTIVE:To present prenatal diagnosis of mosaic trisomy 2. MATERIALS AND METHODS:A 29-year-old woman underwent amniocentesis at 17 weeks of gestation because of abnormal maternal serum screening, and the cytogenetic result was 47,XY,+2[8]/46,XY[22]. She underwent repeated amniocentesis at 19 weeks of gestation. Interphase fluorescence in situ hybridization (FISH), array comparative genomic hybridization (aCGH), and quantitative fluorescent polymerase chain reaction (QF-PCR) were performed on uncultured amniocytes. Ultrasound at 22 weeks of gestation revealed severe oligohydramnios, intrauterine growth restriction, and ventricular septal defect. The pregnancy was terminated at 22 weeks of gestation. Cytogenetic analysis was performed on parental blood, cultured amniocytes, cord blood, skin, liver, lung, umbilical cord, amnion, and placenta. aCGH analysis was performed on cord blood, skin, and liver. RESULTS:In the samples of uncultured amniocytes, interphase FISH detected 11.1% (13/117) mosaicism for trisomy 2, aCGH analysis showed the result of arr [hg19] 2p25.3q37.3 (0-242,936,883)×2.46, and QF-PCR excluded uniparental disomy 2. QF-PCR on placenta revealed trisomy 2 derived from maternal meiosis I non-disjunction. Cytogenetic analysis revealed the following results: cultured amniocytes: 46,XY[21 colonies]; cord blood: 46,XY[40 cells]; skin: 46,XY[40 cells]; lung: 46,XY[40 cells]; liver: 47,XY,+2[4 cells]/46,XY[36 cells]; umbilical cord: 47,XY,+2[4 cells]/46,XY[36 cells]; amniotic membrane: 47,XY,+2[20 cells]/46,XY[20 cells]; and placenta: 47,XY,+2[40 cells]. The fetus postnatally manifested facial dysmorphism and preaxial polydactyly of the hand. CONCLUSION:Interphase FISH and aCGH analyses on uncultured amniocytes are useful for rapid confirmation of low-level mosaic trisomy 2 at amniocentesis.
journal_name
Taiwan J Obstet Gynecoljournal_title
Taiwanese journal of obstetrics & gynecologyauthors
Chen CP,Chen YY,Chern SR,Wu PS,Su JW,Chen YT,Lee CC,Chen LF,Wang Wdoi
10.1016/j.tjog.2013.06.004subject
Has Abstractpub_date
2013-09-01 00:00:00pages
395-400issue
3eissn
1028-4559issn
1875-6263pii
S1028-4559(13)00124-1journal_volume
52pub_type
杂志文章abstract:OBJECTIVE:To identify characteristics and pregnancy outcomes among pregnant illicit drug users living in an urban area, and to describe trends in drug use over an 8-year period. MATERIALS AND METHODS:Data on pregnant women living in the Bangkok Metropolitan Region who delivered at our institution during 2008-2015 were...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2017.12.014
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVES:We evaluated the role of three-dimensional power Doppler ultrasound (3D PD-US) to detect endometrial lesions in women with postmenopausal endometrial bleeding. MATERIALS AND METHODS:In this prospective observational study, from January 2009 to November 2012, we recruited 225 postmenopausal women with postme...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2013.10.043
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVE:We present prenatal diagnosis of hydrancephaly and enlarged cerebellum and cisterna magna in a fetus with thanatophoric dysplasia type II (TD2) and a review of prenatal diagnosis of brain anomalies associated with TD. CASE REPORT:A 33-year-old woman was referred for genetic counseling at 25 weeks of gestatio...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.tjog.2017.12.020
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVE:To compare the clinical features of tuboovarian abscess (TOA) in pre- and postmenopausal women. MATERIALS AND METHODS:Between January 1992 and December 2000, all patients with surgically documented TOA at National Taiwan University Hospital were enrolled into this retrospective study. Salient information wit...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/S1028-4559(09)60231-X
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to propose a method using saline lubrication and two glass slides to reduce the proportion of inadequate Pap smears. MATERIALS AND METHODS:This was a retrospective study of patients at a medical center in eastern Taiwan that performs 5000-6000 Pap smears annually. The extracted data ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2020.09.018
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:This study aims to validate the BACs-on-Beads (BoB) technology as a robust and high throughput method for pre-implantation genetic screening (PGS) for aneuploidy. MATERIAL AND METHODS:The performances with respect to the sensitivity, specificity, success rate and detection rate of this technique from new BoB...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2017.01.011
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:National health insurance coverage for the laparoscopic staging surgery for patients with stage IA endometrial cancer started from April 2014 in Japan. We conducted this retrospective study to evaluate the surgical outcomes of the laparoscopic surgery for patients with low-risk endometrial cancer compared wit...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2018.11.019
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:Acardiac twin occurs in 1:35,000 pregnancies. Several techniques have been described to treat this condition. Some techniques have been suggested as golden standard; however, new are still being tried. CASE REPORT:This is a case of a 32-year-old patient who had successful ablation of the acardiac twin with H...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2014.04.033
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVES:To study the operative outcomes of single-port laparoscopic hysterectomy in uteri greater than 500 g, using either laparoscopic assisted vaginal hysterectomy (LAVH) or laparoscopic supracervical hysterectomy (LSH). MATERIALS AND METHODS:78 patients were included in a single institute by a single surgeon fro...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2020.05.006
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:This study aimed to investigate the risk of birth weights over 4000 g (macrosomia) in association with following the 2009 American Institute of Medicine (AIOM) recommendations. MATERIALS AND METHODS:Seventy-six nondiabetic women who delivered a singleton, term macrosomic fetus and 82 women who delivered a si...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2013.05.001
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:To test whether the interleukin-4 (IL-4) gene polymorphisms could be used as markers of susceptibility for preeclampsia in Taiwan. MATERIALS AND METHODS:This study included 78 women with preeclampsia and 125 normal controls. A polymerase chain reaction was used to analyze the variable number of tandem repeat...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2014.04.017
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVE:To assess the long-term outcomes of laparoscopic staging surgery (LSS) in treating patients with endometrial carcinoma. MATERIALS AND METHODS:Patients with endometrial cancer who underwent LSS between June 1995 and June 2014 were prospectively registered. Perioperative data, complications, disease recurrence...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2016.04.035
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:Human-embryonic-stem-cell (hESC) lines derived from chromosomally or genetically abnormal embryos obtained following preimplantation genetic diagnosis are valuable in investigating genetic disorders. MATERIALS AND METHODS:In this study, a new hESC line, Center of Clinical Reproductive Medicine 8 (CCRM8) was ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2015.08.003
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:Many women quit smoking during pregnancy resume in postpartum period and difficult to prevent. No studies had focused on their psychosocial response in Taiwan. We analyzed data from a trial of Taiwan Smoker's Helpline (TSH) to determine factors associated with smoking relapse after delivery. MATERIALS AND ME...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.tjog.2019.07.015
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:Obstetricians have longer work hours and work hour restriction of employed physicians will be implemented thereafter. This study was to survey the impact of work hour restriction and determine the weekly work hours of obstetricians. MATERIALS AND METHODS:Since December 1, 2017, to January 31, 2018, a questio...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2018.10.005
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVE:Melilotus officinalis (L.) Pall. is commonly used for treating bronchitis, painful menstruation, hemorrhoids, kidney stones, ulcers of the eyes, earache, and hardening and swelling of uterus. The European Medicines Agency reported the use of M. officinalis orally against stomach ache, gastric ulcer, and disor...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2020.01.008
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:Comparing the safety and effectiveness of the pulsed bipolar (PK) system and conventional electrosurgery in laparoscopic myomectomy (LM). MATERIALS AND METHODS:Retrospective chart review of 194 women with symptomatic uterine fibroids undertaken LM was performed. Cases of LMs with PK cutting forceps were comp...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2009.05.002
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the concurrent interaction of laparoscopic and robotic-assisted surgery in the initial learning period of endometrial cancer staging. MATERIALS AND METHODS:A retrospective cohort study was performed for the first 44 consecutive patients with endometrial cancer underwent laparoscopic (LSS) or robo...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2017.10.014
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:Sea buckthorn (Hippophae rhamnoides L.) and St. John's wort (Hypericum perforatum L.) are used as an emmenagog and for the treatment of other gynecological disorders including uterus inflammation and endometriosis. The aim of the present study is to investigate the potential of a mixture of sea buckthorn and ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2015.01.006
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:Endometriosis-associated epithelial ovarian cancer (EOC) is a specific category of EOC, containing either endometrioid or clear cell carcinoma subtype. The characteristic of endometriosis-associated EOC includes an early stage at the diagnosis, presence of single histology type, and better prognosis. The sync...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type:
doi:10.1016/j.tjog.2020.03.024
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:Primary adenoid cystic carcinoma (ACC) of Bartholin's gland is a rare gynecologic malignancy. We report two cases from primary treatment to recurrence and the adjuvant treatment. CASE REPORT:A woman aged 37 years presented with a mass on the right posterior labia minor and underwent right radical hemi-vulvec...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.tjog.2012.10.005
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to describe the natural history and outcomes of fetal congenital cystic adenomatoid malformation (CCAM) of the lung in three antenatally diagnosed cases. CASE REPORT:Three women whose fetuses had CCAM of the lung between 2004 and 2006 chose to continue their pregnancies. We followed...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/S1028-4559(09)60304-1
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:To assess the effect of metalloestrogen cadmium (Cd) on the proliferation of endometrial stromal cells (ESC) isolated from the eutopic endometrium of women with endometriosis MATERIALS AND METHODS:ESC were isolated from eutopic endometrial samples from 10 women with endometriosis and 10 women without endomet...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2013.10.015
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate factors associated with thrombosis that may contribute to recurrent pregnancy loss (habitual abortion), specifically differences in serum levels of platelet-activating factor and thrombin-activatable fibrinolysis inhibitor (carboxypeptidase B2) between women with a his...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2015.06.013
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:To determine the psychological response of cervical human papillomavirus (HPV) infected women. MATERIALS AND METHODS:Twenty oncogenic or high-risk HPV infected cases were collected by purposive sampling, and a 2-hour in-depth interview was carried out with 20 women at a tertiary referring medical center. The...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2011.01.035
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:To analyze the interaction between ACP1 and PTPN22 concerning their effects on the growth of the tumor. In previous paper we have shown (i) that ACP1*B/*B genotype of ACP1 is negatively associated with the growth of leiomyomas and (ii) that there is a negative association of *C/*C genotype of PTPN22 with tumo...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2018.06.017
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to define the pregnancy and oncologic outcomes after fertility-sparing treatment of atypical hyperplasia (AH)/endometrial intraepithelial neoplasia (EIN) and early-stage endometrioid endometrial cancer (EEC). MATERIALS AND METHODS:The retrospective cohort study included patients...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2020.03.014
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the clinical significance of the combination of cancer antigen-125 (CA-125), human epididymis protein 4 (HE4), and progesterone for the identification of ovarian masses in patients with suspected early stage ovarian cancer (OC). MATERIALS AND METHODS:This was a case-control, single-center study o...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2015.10.006
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:Pregnancy-associated death is defined by the American College of Obstetricians and Gynecologists as "a death of a woman while pregnant or within 1 year of termination of pregnancy, irrespective of the cause of death." We sought to determine pregnancy-associated mortality ratio (PAMR) in Taiwan and to compare ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2016.04.007
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:Burkitt's lymphoma (BL) occurs mostly in children; bilateral ovarian involvement mimicking a gynecologic malignancy in adults is extremely rare. Here, we report a patient with BL mimicking a gynecologic tumor. CASE REPORT:A 50-year-old Taiwanese woman presented with the complaint of persistent lower abdomina...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/S1028-4559(09)60217-5
更新日期:2006-06-01 00:00:00