Abstract:
:Uncrimping of collagen fibers in the arterial wall is an integral process in regulating the macro-level mechanical response of arteries. Uncrimping of collagen fibers leads to a gradual, but significant strain-stiffening response of the artery at physiological pressures and prevents overdistention at elevated pressures. In this study, we imaged adventitial collagen fibers from fresh primate arteries using two-photon excitation microscopy while subjecting the arteries to physiological inflation pressures and axial stretches. The imaging focal plane was fixed at a constant radial location in the adventitial wall by adjusting the focal distance as the arteries inflated, allowing for the continuously monitoring of the uncrimping process of a single region of collagen fibers. Digital image correlation was then applied to the sequential images to assess and correlate the local displacements to manual traces of selected reference fibers and their engagements. We found that the collagen fibers of interest became fully engaged at a luminal pressure of 20mmHg, this was then followed by rotation of these fibers as the bulk artery continued to dilate. This technique helps to further the understanding of the uncrimping process of collagen fibers under physiological loads, which can aid in the development of more accurate microstructural constitutive models.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Wang R,Brewster LP,Gleason RL Jrdoi
10.1016/j.jbiomech.2013.08.001subject
Has Abstractpub_date
2013-10-18 00:00:00pages
2726-9issue
15eissn
0021-9290issn
1873-2380pii
S0021-9290(13)00381-3journal_volume
46pub_type
杂志文章abstract::Tendon curvature plays a key role in mechanical gain (amplifying the joint excursion relative to fiber length change) during joint motion, but the mechanism remains unresolved. A three-dimensional finite element (FE) model was used to investigate the influence of intramuscular fiber orientation upon the curvature patt...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2016.09.014
更新日期:2016-10-03 00:00:00
abstract::It is well accepted that the steady-state isometric force following active stretching of a muscle is greater than the steady-state isometric force obtained in a purely isometric contraction at the same length. This property of skeletal muscle has been called residual force enhancement (FE). Despite decades of research...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2008.06.007
更新日期:2008-08-28 00:00:00
abstract::This paper is concerned with a mathematical model analysis of the patellofemoral joint in the human knee, taking into account the articular surface geometry and mechanical properties of the ligament. It was made by the application of a computer-aided design theory (previously studied) and it was possible to express th...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(91)90331-g
更新日期:1991-01-01 00:00:00
abstract::An arterial graft with a corrugated cylindrical cross-section has been proposed as a partial solution to the problem of elastic stiffness mismatch between conventional grafts and arterial tissue (Trescony et al., 1994, US Patent 5,282, 847 (granted February 1 1994)). A two-dimensional ring theory model and a finite el...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(98)00084-0
更新日期:1998-08-01 00:00:00
abstract::Theoretical concerns about the use of cemented or press-fit stems in revision total knee arthroplasty (TKA) include stress shielding with adverse effects on prosthesis fixation. Revision TKA components are commonly stemmed to protect the limited autogenous bone stock remaining. Revision procedures with the use of stem...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2007.10.006
更新日期:2008-01-01 00:00:00
abstract::The differences between the assessments performed with and without the point cluster technique (PCT) for knee joint motions during the high-risk movements associated with non-contact anterior cruciate ligament (ACL) injuries have not been reported. This study aims to examine the differences between PCT and non-PCT ass...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2011.05.001
更新日期:2011-07-07 00:00:00
abstract::A technique for registering vibration and deformation patterns has been adapted for the measurement of whole-body vibration in humans. Double-exposure holographic interferometry produces three dimensional pictures of the body, allowing exact measurement of the subject's movement between the two pulses. In this study a...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(84)90036-8
更新日期:1984-01-01 00:00:00
abstract::The purpose of this study was to investigate the effects of temperature, velocity and load on the gliding resistance (GR) of flexor digitorum profundus (FDP) tendons in a human cadaver model. A total of 40 FDP tendons from the index through small digits of ten human cadavers were tested to assess the effect of tempera...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2011.01.011
更新日期:2011-04-29 00:00:00
abstract::Achieving stability is a prerequisite for allowing bone to grow into the porous surface of non-cemented acetabular cups. The purpose of this study is to estimate the effects of interfacial characteristics on relative cyclical micromotion between cup and bone during gait in the immediate postoperative phase. The techni...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(00)00112-3
更新日期:2001-01-01 00:00:00
abstract::Current motion capture techniques all have shortcomings when applied to the 3D quantitative evaluation of thumb base motion. Dynamic CT might overcome these shortcomings but, so far, robustness of this technique in more than one specimen has not yet been demonstrated. The aim of the current study is to further evaluat...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2016.05.008
更新日期:2016-06-14 00:00:00
abstract::Linking human mechanical work to physiological work for the purpose of developing a model of physical fatigue is a complex problem that cannot be solved easily by conventional biomechanical analysis. The purpose of the study was to determine if two nonlinear analysis methods can address the fundamental issue of utiliz...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2009.06.011
更新日期:2009-09-18 00:00:00
abstract::Exposure following pelvic organ prolapse repair has been observationally associated with wrinkling of the implanted mesh. The purpose of this study was to quantify the impact of variable boundary conditions on the out-of-plane deformations of mesh subjected to tensile loading. Using photogrammetry and surface curvatur...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2015.02.061
更新日期:2015-06-25 00:00:00
abstract::Rigid body attitude and single-joint kinematics are typically expressed using three Cardan angles which represent rotations in anatomical planes. It was recently shown in the Biomechanics literature that Cardan angles inaccurately estimate true mean attitude due to an important mathematical inadequacy: attitude under-...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2020.109976
更新日期:2020-10-09 00:00:00
abstract::Twelve seated male subjects were exposed to 15 vibration conditions to investigate the nature and mechanisms of the non-linearity in biomechanical response. Subjects were exposed to three groups of stimuli: Group A comprised three repeats of random vertical vibration at 0.5, 1.0 and 1.5 ms(-2) r.m.s. with subjects sit...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2005.09.024
更新日期:2006-01-01 00:00:00
abstract::Coronary artery disease results in blockages or narrowing of the artery lumen. Drug eluting stents (DES) were developed to replace bare metal stents in an effort to combat re-blocking of the diseased artery following treatment. The numerical models developed within this study focus on representing the changing trends ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2013.09.017
更新日期:2014-01-03 00:00:00
abstract::While measuring knee motion in all six degrees of freedom is important for understanding and treating orthopaedic knee pathologies, traditional motion capture techniques lack the required accuracy. A variety of model-based biplane fluoroscopy techniques have been developed with sub-millimeter accuracy. However, no stu...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2012.08.045
更新日期:2012-11-15 00:00:00
abstract::We previously developed a load-adaptive bone modelling and remodelling simulation model that can predict changes in the bone micro-architecture as a result of changes in mechanical loading or cell activity. In combination with a novel algorithm to estimate loading conditions, this offers the possibility for patient-sp...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2012.06.031
更新日期:2012-09-21 00:00:00
abstract::Which of the elementary components (hydroxyapatite (HA) crystals, collagen, non-collagenous organic matter, water) do significantly contribute to the ultrastructural elastic stiffness magnitude and anisotropy of mineralized tissues; and how, i.e. through which shapes and assemblages (which micromechanical morphology)?...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(02)00080-5
更新日期:2002-09-01 00:00:00
abstract::The nonlinear stress-strain characteristics of the human menisci were determined by uniaxial elongation tests performed on circumferential and radial specimens prepared from different regions, layers, and locations. The properties of the collagen fibers and the matrix were calculated using the test results along with ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(94)00081-e
更新日期:1995-04-01 00:00:00
abstract::Locomotion of the horse is simulated using a mathematical model based on rigid body dynamics. A general method to generate the equations of motion for a two-dimensional rigid body model with an arbitrary number of hinge joints is presented and a numerical solution method, restricted to tree-structured models, is descr...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(89)90182-6
更新日期:1989-01-01 00:00:00
abstract::In high knee flexion, contact between the posterior thigh and calf is expected to decrease forces on tibiofemoral contact surfaces, therefore, thigh-calf contact needs to be thoroughly characterized to model its effect. This study measured knee angles and intersegmental contact parameters in fifty-eight young healthy ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2017.11.022
更新日期:2018-01-23 00:00:00
abstract::Fixation failure of glenoid components is the main cause of unsuccessful total shoulder arthroplasties. The characteristics of these failures are still not well understood, hence, attempts at improving the implant fixation are somewhat blind and the failure rate remains high. This lack of understanding is largely due ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2009.10.019
更新日期:2010-03-03 00:00:00
abstract::In highly aligned connective tissues, such as tendon, collagen fibrils are linked together by proteoglycans (PGs). Recent mechanical and theoretical studies on tendon micromechanics have implied that PGs mediate mechanical interactions between adjacent collagen fibrils. We used transmission electron microscopy to obse...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2005.12.011
更新日期:2007-01-01 00:00:00
abstract::Morphometrical and postural features of the cervical spine are supposed to significantly influence its biomechanical behaviour. However, the effects of these geometrical parameters are quite difficult to evaluate. An original numerical method is proposed in order to automatically generate parametric and subject-specif...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2009.04.007
更新日期:2009-07-22 00:00:00
abstract::A new technique to study the mechanical properties of collagen lattices or dermal equivalents is described. With the help of the load-extension curve obtained with a uniaxial traction apparatus, a stiffness modulus varying from 0.06 to 1 MPa is calculated from the studied parameters (duration of culture, collagen and ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(92)90250-5
更新日期:1992-01-01 00:00:00
abstract::The paper defines the term coordination interval (CI), suggesting that it should replace the term electromechanical delay (EMD), if this parameter is determined in vivo for a muscle functioning in a biomechanical system with considerable mobility, but not in a kinematic pair with one degree of rotational freedom (DOF)...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(94)90211-9
更新日期:1994-02-01 00:00:00
abstract::This study is aimed at the analysis of articular contact in a three-dimensional mathematical model of the human knee-joint. In particular the effect of articular contact on the passive motion characteristics is assessed in relation to experimentally obtained joint kinematics. Two basically different mathematical conta...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(91)90019-j
更新日期:1991-01-01 00:00:00
abstract::A finite element model was used to investigate the counter-intuitive experimental observation that some regions of the aponeuroses of a loaded and contracting muscle may shorten rather than undergo an expected lengthening. The model confirms the experimental findings and suggests that pennation angle plays a significa...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2010.01.005
更新日期:2010-05-07 00:00:00
abstract::The micromechanical environment of bone is crucial to understanding both bone fracture and mechanobiological responses of osteocytes, yet few techniques exist that are capable of measuring strains on the micrometer scale. A method for measuring micrometer level strains has been developed based on digital image correla...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2013.06.003
更新日期:2013-08-09 00:00:00
abstract::In this paper, a novel multi-slice ultrasound (US) image calibration of an intelligent skin-marker used for soft tissue artefact compensation is proposed to align and orient image slices in an exact H-shaped pattern. Multi-slice calibration is complex, however, in the proposed method, a phantom based visual alignment ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2016.12.030
更新日期:2017-09-06 00:00:00