Initial use of endothelial progenitor cells capturing stents in paediatric congenital heart disease.

Abstract:

INTRODUCTION:Stenosis, mediated by neointimal hyperplasia and thrombosis, is a major limiting factor in successful stent implantation. The introduction of a stent, coated in its endoluminal surface by antihuman CD34 antibodies with endothelial progenitor cell-capturing properties, opens the possibility of promoting a rapid and normal functioning coverage by endothelium and thus avoids both an excessive cell proliferation within stent and the need for long-term dual antiplatelet therapy. These stents, developed for adult coronary artery disease, have not yet been implanted in children or in those with congenital heart disease. OBJECTIVE AND METHODS:In this paper, we describe the implantation of Genous® stents in three children with cyanotic congenital heart disease and obstructed systemic-to-pulmonary shunts. We describe the use of this stent and address its potential feasibility in paediatric congenital heart disease. RESULTS:To maintain the patency of two modified Blalock-Taussig shunts and one ductus arteriosus, four Genous® stents were implanted in three infants with cyanotic heart disease. All procedures were immediately successful, with resolution of stenosis and improvement in transcutaneous oxygen saturation from 66% ± 3.6% to 92% ± 2.6%. In the follow-up, one stent had no occlusion; however, the remaining two had partial occlusion after 5 and 5.5 months, which were successfully managed with balloon dilatation preceding elective definitive surgical correction. CONCLUSION:In our preliminary experience, we demonstrated that Genous® stent implantation was feasible in infants with complex congenital heart disease. Additional studies with larger samples and longer follow-up are required to confirm the potential benefits of this technology in this clinical setting.

journal_name

Cardiol Young

journal_title

Cardiology in the young

authors

Cabanelas N,Martins JD,Pinto F

doi

10.1017/S1047951113001376

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

900-4

issue

5

eissn

1047-9511

issn

1467-1107

pii

S1047951113001376

journal_volume

24

pub_type

杂志文章
  • Immediate and early results of closure of moderate to large patent arterial ducts using the new Amplatzer device.

    abstract:OBJECTIVES:Our aim was to assess the immediate and short term results of closure of moderate and large patent arterial ducts using the self-expanding and repositionable Amplatzer device. METHOD:We attempted closure in 25 patients (10 Females and 15 males) using the Amplatzer occluder. Their median age was 48 months wi...

    journal_title:Cardiology in the young

    pub_type: 临床试验,杂志文章

    doi:10.1017/s1047951100009124

    authors: Marwah A,Radhakrishnan S,Shrivastava S

    更新日期:2000-05-01 00:00:00

  • Dexmedetomidine utilisation and outcomes of children with trisomy 21 undergoing congenital heart disease surgery.

    abstract:INTRODUCTION:The diagnosis of trisomy 21 in children has been associated with failed extubation after CHD surgery. Dexmedetomidine may be a useful agent to improve postoperative outcomes in these patients, such as ventilator time, ICU length of stay, or hospital length of stay. MATERIALS AND METHODS:The Pediatric Heal...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951114001462

    authors: Moffett BS,Mossad EB,Tobias JD,Cabrera AG

    更新日期:2015-06-01 00:00:00

  • Single right coronary artery with right ventricular fistula and congenital absence of left coronary artery: an extremely rare combination.

    abstract::We report an extremely rare case of a 14-month-old girl who was diagnosed with a single right coronary artery with coronary artery fistula communicating with the right ventricle and congenital absence of left coronary artery. Angiography showed a dilated and tortuous single right coronary artery draining into the righ...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951119002105

    authors: Yoldaş T,Beyazal M,Örün UA

    更新日期:2019-11-01 00:00:00

  • The impact of the severity of disease and social disadvantage on quality of life in families with congenital cardiac disease.

    abstract:OBJECTIVE:Increasing rates of survival have raised the question of medical and psychosocial factors contributing to quality of life of patients with congenital cardiac disease. We investigated the impact of the severity of disease, and social disadvantage, on the quality of life of patients and their primary caregivers...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951105002118

    authors: Goldbeck L,Melches J

    更新日期:2006-02-01 00:00:00

  • Respiratory syncytial virus and complete heart block in a child.

    abstract::The common respiratory syncytial virus has been associated with cardiac involvement, usually tachyarrhythmias and occasionally myocarditis. A child is described who probably developed a complete heart block following respiratory syncytial bronchiolitis. Such an association needs to be considered if the heart is struct...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951109990102

    authors: Menahem S

    更新日期:2010-02-01 00:00:00

  • A model for a nurse-led programme of bedside placement of peripherally inserted central catheters in neonates and infants with congenital cardiac disease.

    abstract:BACKGROUND:Neonates and infants with congenital and acquired cardiac disease often require placement of central venous lines for extended intravenous therapy. It may be advantageous to avoid the larger venous vessels of the head and neck and lower extremities in order to preserve these for future interventions and ther...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951110000090

    authors: King DS,da Cruz E,Kaufman J

    更新日期:2010-06-01 00:00:00

  • Factors affecting vascular access complications in children undergoing congenital cardiac catheterization.

    abstract:BACKGROUND:Complications at the vascular access sites are among the most common adverse events in congenital cardiac catheterization. The use of small-gauge catheters may reduce these events; however, other factors can contribute to the development of vascular complications. OBJECTIVES:To determine factors associated ...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951111000989

    authors: Roushdy AM,Abdelmonem N,El Fiky AA

    更新日期:2012-04-01 00:00:00

  • Anomalous origin of a single coronary artery from the pulmonary artery associated with patent ductus arteriosus.

    abstract::We report an unusual case of a 12-month-old boy diagnosed with anomalous origin of a single coronary artery from the pulmonary artery associated with patent ductus arteriosus. The patient survival was attributed to left-to-right shunt (patent ductus arteriosus) allowing for appropriate myocardial perfusion. Successful...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951120001328

    authors: Hugues N,Dommerc C,Pretre R

    更新日期:2020-07-01 00:00:00

  • Electrocardiogram before starting stimulant medications: to order or not?

    abstract::D is an 8-year-old boy brought to his paediatrician for evaluation. His mother is concerned as his teacher has been frequently complaining that he is very restless and often disturbs the rest of the class by getting up on some pretext or the other. He is unable to concentrate on his work and gets distracted very easil...

    journal_title:Cardiology in the young

    pub_type: 信件

    doi:10.1017/S1047951115001274

    authors: Aggarwal V,Aggarwal A,Khan D

    更新日期:2016-01-01 00:00:00

  • Role of toxicological determinations of amphetamines and cannabinoids in hair of adolescent patients in cardiologic diagnostic management.

    abstract:BACKGROUND:Parental suspicions that the child may possibly take narcotics may be substantiated by hair analysis, which may not only identify the narcotic abuse profile, but also define the minimum period of narcotic usage. OBJECTIVE:A toxicological hair analysis aiming at detecting the presence of amphetamines and can...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951111000667

    authors: Kłys M,Szydłowski L,Rojek S

    更新日期:2012-02-01 00:00:00

  • Brain natriuretic peptide can be a useful biochemical marker for myocarditis in patients with Kawasaki disease.

    abstract:UNLABELLED:So as to determine the value of brain natriuretic peptide in the plasma as a biochemical marker for myocarditis of Kawasaki disease, we studied 69 patients. The blood samples, electrocardiograms and cross-sectional echocardiograms were obtained before the commencement of treatment and in the convalescent pha...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/s1047951102000318

    authors: Kawamura T,Wago M

    更新日期:2002-03-01 00:00:00

  • Accuracy of cardiac auscultation in detection of neonatal congenital heart disease by general paediatricians.

    abstract:BACKGROUND:Challenges remain in the judgement of pathological murmurs in newborns at maternity hospitals, and there are still many simple major CHD patients in developing countries who are not diagnosed in a timely fashion. This study aimed to evaluate the accuracy of cardiac auscultation on neonatal CHD by general pae...

    journal_title:Cardiology in the young

    pub_type: 杂志文章,多中心研究

    doi:10.1017/S1047951119000799

    authors: Zhao QM,Niu C,Liu F,Wu L,Ma XJ,Huang GY

    更新日期:2019-05-01 00:00:00

  • The role of vasopressin in treating systemic inflammatory syndrome complicated by right ventricular failure.

    abstract::Severe right ventricular failure complicated a postoperative systemic inflammatory response in a 33-year-old woman after surgical repair of congenital cardiac malformations. Volume loading, and high doses of catecholamines, failed to produce improvement, but treatment with vasopressin improved all haemodynamic paramet...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951105000193

    authors: Vida VL,Mack R,Castañeda AR

    更新日期:2005-02-01 00:00:00

  • The registry of anomalous aortic origin of the coronary artery of the Congenital Heart Surgeons' Society.

    abstract::The anomalous aortic origin of a coronary artery from the wrong sinus of Valsalva with interarterial, intramural, and/or intraconal course is a rare congenital anomaly that is associated with a high risk of sudden death in children. The Congenital Heart Surgeons' Society established the Registry of Anomalous Aortic Or...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951110001095

    authors: Brothers JA,Gaynor JW,Jacobs JP,Caldarone C,Jegatheeswaran A,Jacobs ML,Anomalous Coronary Artery Working Group.

    更新日期:2010-12-01 00:00:00

  • Should we standardise the pre-operative management of babies with complete transposition?

    abstract:BACKGROUND:Complete transposition is the most common form of neonatal cyanotic heart disease. The management of this condition has changed markedly in the last decade and there appears to be a significant variation between centres in terms of pre-operative management. OBJECTIVES/METHODS:We surveyed all paediatric card...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/s104795110000812x

    authors: Hornung TS,O'Sullivan JJ

    更新日期:2000-09-01 00:00:00

  • The perspective of ventricular noncompaction as seen by a nonagenarian.

    abstract::The persistence of so-called spongy myocardium was first reported in humans in the 1960s. Subsequently, a few reports described the condition, utilizing inconsistent facts and terminology. In 1990 the first report appeared using the term "noncompaction", and detailed its clinical implications. Following this report, m...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951108001972

    authors: Lurie PR

    更新日期:2008-06-01 00:00:00

  • Sudden improvement in ventricular repolarization abnormality after a short detraining period in an athlete.

    abstract::We describe the case of a 17-year-old male soccer player with T-wave inversion in precordial leads in resting electrocardiography, which also disclosed sinus bradycardia, early repolarization, and increased QRS voltage. These findings strongly suggested cardiomyopathy. The patient's T-wave inversion disappeared during...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951117001287

    authors: Motoki N,Akazawa Y,Hachiya A,Inaba Y

    更新日期:2017-11-01 00:00:00

  • The impact, and surgical implications, of isolated anomalous connection of one pulmonary vein.

    abstract::Partially anomalous pulmonary venous connection of a solitary pulmonary vein in the setting of an intact atrial septum is often subclinical, and the indications for surgical repair are controversial. Here we describe a patient who developed a significant shunt over a period of 10-years. Flow through the anomalously co...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S104795110700159X

    authors: Koh M,Uemura H,Kagisaki K

    更新日期:2007-10-01 00:00:00

  • Timing of removal of pacing wires following paediatric cardiac surgery.

    abstract:BACKGROUND:Temporary percutaneous epicardial pacing wires are routinely placed in children following cardiac surgery. There is uncertainty in clinical practice about the optimum timing for their removal, and practice varies widely both within and between different institutions. AIM:The aim of our study was to describe...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951107001035

    authors: Jowett V,Hayes N,Sridharan S,Rees P,Macrae D

    更新日期:2007-10-01 00:00:00

  • Perioperative feeding management of neonates with CHD: analysis of the Pediatric Cardiac Critical Care Consortium (PC4) registry.

    abstract:UNLABELLED:Introduction The optimal perioperative feeding strategies for neonates with CHD are unknown. In the present study, we describe the current feeding practices across a multi-institutional cohort. METHODS:Inclusion criteria for this study were as follows: all neonates undergoing cardiac surgery admitted to the...

    journal_title:Cardiology in the young

    pub_type: 杂志文章,多中心研究

    doi:10.1017/S1047951115002474

    authors: Alten JA,Rhodes LA,Tabbutt S,Cooper DS,Graham EM,Ghanayem N,Marino BS,Figueroa MI,Chanani NK,Jacobs JP,Donohue JE,Yu S,Gaies M

    更新日期:2015-12-01 00:00:00

  • Anomalous origin of the main stem of the left coronary artery from the non-facing sinus of valsalva associated with sudden death in a young athlete.

    abstract::A young female athlete is described with anomalous origin of the main stem of the left coronary artery from the non-facing sinus of Valsalva who sustained myocardial infarction and died suddenly after physical exertion. Autopsy findings illustrated the mechanistic importance of acute angle take-off of the left main co...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/s1047951100006624

    authors: Hamamichi Y,Okada E,Ichida F

    更新日期:2000-03-01 00:00:00

  • The distance from the Amplatzer septal occluder to the mitral valve in patients undergoing interventional closure of defects in the oval fossa increases with growth of the patient.

    abstract::The Amplatzer septal occluder is an alternative to operative closure of atrial septal defects within the oval fossa. An issue when deploying the device is its distance from the mitral valve. The purpose of this study is to determine how this distance changes with growth of the patient. We identified, through a review ...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951104005050

    authors: English RF,Ettedgui JA

    更新日期:2004-10-01 00:00:00

  • Extreme exercise dislike of a toddler due to a patent foramen ovale.

    abstract::A 5-year-old girl presented with chronic fatigue and extreme exercise intolerance. After countless doctor visits, investigations, and hospital admissions, striking desaturation during exercise test pointed to a cardiovascular problem. Desaturation as a result of right-to-left shunting through a patent foramen ovale du...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951118002044

    authors: Grootaers C,Roggen M,Gewillig M

    更新日期:2019-02-01 00:00:00

  • Twiddler's syndrome with occult lead insulation damage in a child with epicardial pacemaker leads.

    abstract::We present a rare case of incidentally diagnosed Twiddler's syndrome in a child 7 years after implantation of a dual-chamber pacemaker system with epicardial leads. During revision, an insulation defect of the ventricular lead was evident, despite unremarkable prior pacemaker lead testing. The lead was repaired and a ...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951120001031

    authors: Kramer P,Berger F,Peters B

    更新日期:2020-06-01 00:00:00

  • Atrial fibrillation in a child with COVID-19 infection.

    abstract::The SARS-CoV-2 (COVID-19) pandemic has challenged our initial predictions of its ramifications, both short and long term. Cardiovascular manifestations of COVID-19 in children remain a topic of investigation as literature is lacking. We describe new onset atrial fibrillation in a child with a history of COVID-19 infec...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951120003893

    authors: Santi AD,Aquino P,Dorfman M

    更新日期:2020-10-19 00:00:00

  • Real-time three-dimensional trans-oesophageal echocardiography-guided balloon dilation of pulmonary venous pathway obstruction in a patient with dextro-transposition of the great arteries after atrial switch surgery: a case report.

    abstract::A percutaneous transcatheter balloon dilation of a pulmonary venous pathway obstruction was successfully performed in a 40-year-old patient after a Mustard procedure. During the procedure, real-time three-dimensional trans-oesophageal echocardiography demonstrated the morphology of the obstruction. Our case highlights...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951119001045

    authors: Nitta M,Sugano T,Iwata K

    更新日期:2019-07-01 00:00:00

  • Thymidylate synthase gene variation is associated with the risk for conotruncal heart defects in Chinese population.

    abstract::Conotruncal heart defects are considered to be one of the most common types of birth defect worldwide. Genetic disturbances in folate metabolism such as Thymidylate synthase may increase risk for conotruncal heart defects. We evaluated two common Thymidylate synthase polymorphisms, including the 28 bp tandem repeat in...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951118002184

    authors: Wang X,Wei H,Wu Y,Tian Y,Luo L

    更新日期:2018-12-21 00:00:00

  • Berry syndrome: the importance of genetic evaluation before surgical intervention.

    abstract::Berry syndrome is a rare CHD. Approximately 29 cases have been described in the literature. Surgical correction has been successfully performed as well. We report the case of a newborn diagnosed with Berry syndrome who was subsequently diagnosed with trisomy 13. Cytogenetic analysis should be performed before surgical...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951115000256

    authors: Remon JI,Briston DA,Stern KW

    更新日期:2016-01-01 00:00:00

  • The efficacy of echocardiographic criterions for the diagnosis of carditis in acute rheumatic fever.

    abstract:BACKGROUND:There is a great need for echocardiographic criterions for accurate diagnosis of carditis in acute rheumatic fever. AIM:To test the efficacy of proposed echocardiographic criterions for the diagnosis of carditis. MATERIALS AND METHODS:We studied 333 patients suspected of having acute rheumatic fever, under...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951108003107

    authors: Vijayalakshmi IB,Vishnuprabhu RO,Chitra N,Rajasri R,Anuradha TV

    更新日期:2008-12-01 00:00:00

  • Congenital pseudoaneurysm of the mitral-aortic intervalvular fibrosa: a case report.

    abstract::The mitral-aortic intervalvular fibrosa is an area of fibrous continuity between the mitral and aortic valves. We present the first case of a congenital pseudoaneurysm in this region, detected prenatally as an isolated cardiac defect, which was followed-up conservatively postnatally. The diagnosis was confirmed by ech...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951117000890

    authors: Harrington JK,Glickstein J,Shah A

    更新日期:2017-05-29 00:00:00