Abstract:
UNLABELLED:So as to determine the value of brain natriuretic peptide in the plasma as a biochemical marker for myocarditis of Kawasaki disease, we studied 69 patients. The blood samples, electrocardiograms and cross-sectional echocardiograms were obtained before the commencement of treatment and in the convalescent phase. RESULTS:The mean concentration of brain natriuretic peptide in the plasma was 73.2 +/- 107.7 (mean +/- SD) pg/ml in the acute phase, and 7.9 +/- 7.5 pg/ml in the convalescent phase. We checked the electrocardiograms to find abnormal Q waves, elevation or depression of the ST segments, change in the pattern of the QRS complexes, and flattening or inversion of the T wave, all believed to be markers of myocarditis in Kawasaki disease. Those in whom the concentrations were greater than 50 pg/ml in the acute phase showed abnormal electrocardiograms more frequently than did those in whom the values were less than 50 pg/ml (21/29 vs 3/40, p < 0.0001 odds ratio 32.4). Amplitudes of the T wave in standard limb leads were measured both in the acute and convalescent phases, and the differences calculated. We regarded the sum total of these differences as representing "flattening T wave", and we named this variable as the total suppressed T wave voltage. We examined the correlation between the variable and the levels of brain natriuretic peptide in the plasma during the acute phase, demonstrating a significant correlation (r = 0.500, p < 0.0001). We conclude, therefore, that the concentration of brain natriuretic peptide measured in the plasma can be a useful biochemical marker for the myocarditis of Kawasaki disease. When the titer is over 50 pg/ml, the patient probably has an abnormal electrocardiogram and is most likely to have myocarditis.
journal_name
Cardiol Youngjournal_title
Cardiology in the youngauthors
Kawamura T,Wago Mdoi
10.1017/s1047951102000318keywords:
subject
Has Abstractpub_date
2002-03-01 00:00:00pages
153-8issue
2eissn
1047-9511issn
1467-1107journal_volume
12pub_type
杂志文章abstract:BACKGROUND:Kawasaki disease, which is characterised by systemic vasculitides accompanied by acute fever, is regularly treated by intravenous immunoglobulin to avoid lesion formation in the coronary artery; however, the mechanism of intravenous immunoglobulin therapy is unclear. Hence, we aimed to analyse the global exp...
journal_title:Cardiology in the young
pub_type: 杂志文章
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更新日期:2017-11-01 00:00:00
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journal_title:Cardiology in the young
pub_type: 杂志文章,评审
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更新日期:2008-12-01 00:00:00
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更新日期:2017-09-01 00:00:00
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journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951115000256
更新日期:2016-01-01 00:00:00
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更新日期:2012-10-01 00:00:00
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更新日期:2009-09-01 00:00:00
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pub_type: 杂志文章
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journal_title:Cardiology in the young
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更新日期:2002-12-01 00:00:00
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更新日期:2001-05-01 00:00:00
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pub_type: 杂志文章
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更新日期:2015-06-01 00:00:00
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journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951108001881
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVE:To examine the current subjective state of health, and the longitudinal course of psychological well-being, in adult patients with congenital cardiac malformations. METHODS:Our study concerns the second follow-up of a cohort of patients with congenital cardiac malformations. We examined 362 consecutive patie...
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pub_type: 杂志文章
doi:10.1017/S1047951105000351
更新日期:2005-04-01 00:00:00
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更新日期:2005-02-01 00:00:00
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更新日期:2014-08-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1017/S1047951118002020
更新日期:2019-02-01 00:00:00
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journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951110000089
更新日期:2010-06-01 00:00:00
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journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951112001527
更新日期:2012-12-01 00:00:00
abstract::Body mass index, race/ethnicity, and payer status are associated with operative mortality in congenital heart disease (CHD). Interactions between these predictors and impacts on longer term outcomes are less well understood. We studied the effect of body mass index, race/ethnicity, and payer on 1-year outcomes followi...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951120003911
更新日期:2020-11-19 00:00:00
abstract::Endocarditis of congenital coronary fistulas in the cardiac chambers is rare, especially in the paediatric age group. We describe the case of a 9-year-old boy with a fistula from the dilated right coronary artery to the junction of the superior caval vein to the right atrium, complicated by endocarditis. Treatment con...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951117001846
更新日期:2018-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1017/S1047951111000023
更新日期:2011-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1017/S1047951118000860
更新日期:2018-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2005-02-01 00:00:00
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journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s1047951100008441
更新日期:1999-03-01 00:00:00
abstract:INTRODUCTION:Migraine is a common neurovascular disease characterised with recurrent attacks by pain-free periods. It has been suggested that both sympathetic and parasympathetic dysfunctions play a role in its pathophysiology. AIM:The aim of our study was to investigate the ECG changes during attack-free period in ch...
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pub_type: 杂志文章
doi:10.1017/S1047951119000088
更新日期:2019-04-01 00:00:00
abstract::Introduction Neurodevelopmental abnormalities are common in children with CHD and are the highest-priority concerns for parents and professionals following cardiac surgery in childhood. There is no additional routine monitoring of development for children with CHD in the United Kingdom; hence, neurodevelopmental conce...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951117002918
更新日期:2018-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1017/S1047951115001213
更新日期:2016-02-01 00:00:00
abstract::Approximately 32,000 infants are born with CHDs each year in the United States of America. Of every 1000 live births, 2.3 require surgical or transcatheter intervention in the first year of life. There are few more stressful times for parents than when their neonate receives a diagnosis of complex CHD requiring surger...
journal_title:Cardiology in the young
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1017/S1047951118000604
更新日期:2018-07-01 00:00:00
abstract::Cardiac involvement is a rare complication of infection by the influenza B virus. It usually presents with ventricular dysfunction, arrhythmias, or both. We report a 13-year-old boy with clinical, electrocardiographic, and laboratory findings of myocardial ischaemia during an otherwise silent acute infection with infl...
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doi:10.1017/S1047951105000454
更新日期:2005-04-01 00:00:00
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更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Few data are available on the neuropsychological, behavioural, or structural brain imaging outcomes in adolescents who underwent corrective surgery in infancy for tetralogy of Fallot. METHODS:In this single-centre cross-sectional study, we enrolled 91 adolescents (13-16 years old) with tetralogy of Fallot a...
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doi:10.1017/S1047951114000031
更新日期:2015-02-01 00:00:00