Brain natriuretic peptide can be a useful biochemical marker for myocarditis in patients with Kawasaki disease.

Abstract:

UNLABELLED:So as to determine the value of brain natriuretic peptide in the plasma as a biochemical marker for myocarditis of Kawasaki disease, we studied 69 patients. The blood samples, electrocardiograms and cross-sectional echocardiograms were obtained before the commencement of treatment and in the convalescent phase. RESULTS:The mean concentration of brain natriuretic peptide in the plasma was 73.2 +/- 107.7 (mean +/- SD) pg/ml in the acute phase, and 7.9 +/- 7.5 pg/ml in the convalescent phase. We checked the electrocardiograms to find abnormal Q waves, elevation or depression of the ST segments, change in the pattern of the QRS complexes, and flattening or inversion of the T wave, all believed to be markers of myocarditis in Kawasaki disease. Those in whom the concentrations were greater than 50 pg/ml in the acute phase showed abnormal electrocardiograms more frequently than did those in whom the values were less than 50 pg/ml (21/29 vs 3/40, p < 0.0001 odds ratio 32.4). Amplitudes of the T wave in standard limb leads were measured both in the acute and convalescent phases, and the differences calculated. We regarded the sum total of these differences as representing "flattening T wave", and we named this variable as the total suppressed T wave voltage. We examined the correlation between the variable and the levels of brain natriuretic peptide in the plasma during the acute phase, demonstrating a significant correlation (r = 0.500, p < 0.0001). We conclude, therefore, that the concentration of brain natriuretic peptide measured in the plasma can be a useful biochemical marker for the myocarditis of Kawasaki disease. When the titer is over 50 pg/ml, the patient probably has an abnormal electrocardiogram and is most likely to have myocarditis.

journal_name

Cardiol Young

journal_title

Cardiology in the young

authors

Kawamura T,Wago M

doi

10.1017/s1047951102000318

keywords:

subject

Has Abstract

pub_date

2002-03-01 00:00:00

pages

153-8

issue

2

eissn

1047-9511

issn

1467-1107

journal_volume

12

pub_type

杂志文章
  • Severe airway obstruction from a bronchial cast after cardiac transplantation.

    abstract::Plastic bronchitis is a rare and difficult to treat disease process in patients with congenital heart disease. Cardiac transplantation has been used increasingly to reverse this process, especially in single ventricle physiology. This case report demonstrates a foreseeable complication after cardiac transplantation in...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951113001066

    authors: Parent JJ,Darragh RK

    更新日期:2014-08-01 00:00:00

  • Respiratory syncytial virus and complete heart block in a child.

    abstract::The common respiratory syncytial virus has been associated with cardiac involvement, usually tachyarrhythmias and occasionally myocarditis. A child is described who probably developed a complete heart block following respiratory syncytial bronchiolitis. Such an association needs to be considered if the heart is struct...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951109990102

    authors: Menahem S

    更新日期:2010-02-01 00:00:00

  • New outpatient referrals to a tertiary paediatric cardiac centre: evidence of increasing workload and evolving patterns of referral.

    abstract:OBJECTIVES:To assess the volume and range of diagnosis in new patients referred to paediatric cardiac outpatient clinics. METHODS:Data was collected prospectively, using a proforma completed at all outpatient clinics over a period of three months. RESULTS:There were 526 new referrals, representing an increase of almo...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951105000090

    authors: Murugan SJ,Thomson J,Parsons JM,Dickinson DF,Blackburn ME,Gibbs JL

    更新日期:2005-02-01 00:00:00

  • The distance from the Amplatzer septal occluder to the mitral valve in patients undergoing interventional closure of defects in the oval fossa increases with growth of the patient.

    abstract::The Amplatzer septal occluder is an alternative to operative closure of atrial septal defects within the oval fossa. An issue when deploying the device is its distance from the mitral valve. The purpose of this study is to determine how this distance changes with growth of the patient. We identified, through a review ...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951104005050

    authors: English RF,Ettedgui JA

    更新日期:2004-10-01 00:00:00

  • Treatment of familial hypercholesterolaemia in children and adolescents in the last three decades.

    abstract:BACKGROUND:This study evaluated the effectiveness of long-term intensive lipid-lowering therapy in children and adolescents with familial hypercholesterolaemia. METHODS:The charts of 89 children and adolescents with heterozygous familial hypercholesterolaemia among ∼1000 patients treated from 1974 to 2008 were reviewe...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951113000528

    authors: Elis A,Zhou R,Stein EA

    更新日期:2014-06-01 00:00:00

  • The relationship between P-wave dispersion and diastolic functions in diabetic children.

    abstract:OBJECTIVE:The aim of this study was to investigate the relations between the P-wave dispersion and diastolic functions in type 1 diabetic children. PATIENTS:A total of 33 diabetic patients without any cardiovascular disease, with a mean age of 12.3 plus or minus 4.2 years, and 29 healthy controls, with a mean age of 1...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S104795110999031X

    authors: Köken R,Demir T,Sen TA,Kundak AA,Oztekin O,Alpay F

    更新日期:2010-04-01 00:00:00

  • Extreme exercise dislike of a toddler due to a patent foramen ovale.

    abstract::A 5-year-old girl presented with chronic fatigue and extreme exercise intolerance. After countless doctor visits, investigations, and hospital admissions, striking desaturation during exercise test pointed to a cardiovascular problem. Desaturation as a result of right-to-left shunting through a patent foramen ovale du...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951118002044

    authors: Grootaers C,Roggen M,Gewillig M

    更新日期:2019-02-01 00:00:00

  • Clinical features in adults with coronary arterial lesions caused by presumed Kawasaki disease.

    abstract::There exists a population of adults with undiagnosed coronary arterial lesions due to Kawasaki disease occurring before 1967. We report the clinical features in 6 adult males with coronary arterial lesions caused by presumed Kawasaki disease, whose dates of birth ranged from 1945 to 1963. The age of the diagnosed coro...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951107000169

    authors: Tsuda E,Matsuo M,Naito H,Noguchi T,Nonogi H,Echigo S

    更新日期:2007-02-01 00:00:00

  • Diagnosis, clinical features, management, and post-natal follow-up of fetal tachycardias.

    abstract:OBJECTIVE:To evaluate the diagnosis, clinical features, management and post-natal follow-up in consecutive fetuses identified with tachycardia. METHODS:We reviewed consecutive fetuses with tachycardia identified in a single tertiary institution between January, 2001, and December, 2008. We considered several options f...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951109990497

    authors: Lulić Jurjević R,Podnar T,Vesel S

    更新日期:2009-09-01 00:00:00

  • Interatrial communication through the mouth of the coronary sinus.

    abstract:OBJECTIVES:We describe the structure of, and suggest an etiology for, the interatrial communication which can occur through the mouth of the coronary sinus. Based on the study of human embryos, we propose that the defect is best explained by dissolution of the wall of the coronary sinus adjacent to the left atrium, per...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/s104795110001297x

    authors: Knauth A,McCarthy KP,Webb S,Ho SY,Allwork SP,Cook AC,Anderson RH

    更新日期:2002-07-01 00:00:00

  • Echocardiographic screening for rheumatic heart disease in Turkish schoolchildren.

    abstract:BACKGROUND:The aim of this study is to investigate the prevalence of subclinical rheumatic heart disease in schoolchildren aged 5-18 by using portable echocardiography in Ankara, Turkey. METHODS:The portable echocardiography screening was performed by a paediatric cardiologist for all of the cases. The mean age of 255...

    journal_title:Cardiology in the young

    pub_type: 杂志文章,多中心研究

    doi:10.1017/S1047951119002075

    authors: Atalay S,Tutar E,Uçar T,Topçu S,Köse SK,Doğan MT

    更新日期:2019-10-01 00:00:00

  • Isolated retroaortic innominate vein and right aortic arch: a case report and review of literature.

    abstract::Retroaortic course of left innominate vein is a rare venous anomaly which is usually associated with CHD. Isolated retroaortic innominate vein is exceedingly rare with only a handful of reported cases. We report an otherwise healthy newborn with isolated retroaortic innominate vein and right aortic arch, a combination...

    journal_title:Cardiology in the young

    pub_type: 杂志文章,评审

    doi:10.1017/S1047951119001380

    authors: Kohli U

    更新日期:2019-08-01 00:00:00

  • Normal limits for heart rate as established using 24-hour ambulatory electrocardiography in children and adolescents.

    abstract:BACKGROUND:To the best of our knowledge, normal limits of heart rate with respect to gender, and as established using 24-hour ambulatory Holter electrocardiography, have yet to be published for the entire age range of children and adolescents. OBJECTIVES:To establish the normal limits for heart rate in newborns, infan...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951108002539

    authors: Salameh A,Gebauer RA,Grollmuss O,Vít P,Reich O,Janousek J

    更新日期:2008-10-01 00:00:00

  • More lessons learned from the Pediatric Heart Transplant Study.

    abstract::Paediatric heart transplantation has evolved over the last 3 decades. The research group, Pediatric Heart Transplant Study, has been in step with that evolution over the nearly 20 years of its existence by utilising its registry to contribute a wealth of clinical research to the field. The highlights of its studies wi...

    journal_title:Cardiology in the young

    pub_type: 杂志文章,评审

    doi:10.1017/S1047951115000931

    authors: Law YM

    更新日期:2015-08-01 00:00:00

  • Early conversion of classic Fontan conversion may decrease term morbidity: single centre outcomes.

    abstract:BACKGROUND:The initial classic Fontan utilising a direct right atrial appendage to pulmonary artery anastomosis led to numerous complications. Adults with such complications may benefit from conversion to a total cavo-pulmonary connection, the current standard palliation for children with univentricular hearts. METHOD...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S104795111900146X

    authors: Blitzer D,Habib AS,Brown JW,Kean AC,Lin JI,Turrentine MW,Rodefeld MD,Herrmann JL,Kay WA

    更新日期:2019-08-01 00:00:00

  • Plasma adiponectin levels and relations with cytokines in children with acute rheumatic fever.

    abstract:AIM:We aimed to investigate the role of adiponectin in acute rheumatic fever by evaluating correlations with cytokines and acute-phase reactants. METHODS:Patients were divided into three groups by clinical findings. Group 1 included 8 patients with only chorea, Group 2 included 13 patients with arthritis and carditis,...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951114001012

    authors: Ozgen H,Ucar B,Yildirim A,Colak O,Bal C,Kilic Z

    更新日期:2015-06-01 00:00:00

  • Neonatal physiology of the functionally univentricular heart.

    abstract::The neonate with functionally univentricular physiology presents unique challenges to the cardiac team. An integrated approach that applies working knowledge of cardiac anatomy, cardiopulmonary physiology, and basic principles of intensive care is essential to guide management of each individual patient. This requires...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/s1047951104006304

    authors: Nelson DP,Schwartz SM,Chang AC

    更新日期:2004-02-01 00:00:00

  • What is the diagnostic value of the paediatric exercise tolerance test? Results from a UK centre.

    abstract::Purpose The aim of this study was to determine whether the exercise tolerance test can provide diagnostic and prognostic information regarding children and young adults and help predict outcome. METHODS:A total of 87 patients, aged 7-29 years (median 13, mean 13.4) were selected retrospectively. They underwent exerci...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951117000233

    authors: Sajnach-Menke MA,Walpole SC

    更新日期:2017-09-01 00:00:00

  • Intra-operative arrhythmia predicts post-operative arrhythmia and the need for temporary pacing wires.

    abstract:OBJECTIVE:Protocols for the placement of temporary pacing wires vary among institutions. Our current protocol is to selectively place temporary pacing wires in those patients who develop haemodynamically significant intra-operative arrhythmia. We wished to identify how effective our current protocol is at identifying w...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951114000043

    authors: Piggott K,Nehgme R,Decampli W,Pourmoghadam K,Fakioglu H,Blanco C

    更新日期:2015-03-01 00:00:00

  • Successful surgical repair of Uhl's anomaly.

    abstract::We report a case of Uhl's anomaly in a 5-month-old cyanotic infant who presented with thromboembolic stroke and acute hemiparesis. The patient underwent successfully an initial surgical repair, which included exclusion of the right ventricle by patch closure of the tricuspid valve, atrial septectomy and construction o...

    journal_title:Cardiology in the young

    pub_type: 杂志文章,评审

    doi:10.1017/s1047951102000410

    authors: Azhari N,Assaqqat M,Bulbul Z

    更新日期:2002-03-01 00:00:00

  • Effects of milk flow on the physiological and behavioural responses to feeding in an infant with hypoplastic left heart syndrome.

    abstract::Infants with hypoplastic left heart syndrome often experience difficulty with oral feeding, which contributes to growth failure, morbidity, and mortality. In response to feeding difficulty, clinicians often change the bottle nipple, and thus milk flow rate. Slow-flow nipples have been found to reduce the stress of fee...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951116000251

    authors: Pados BF,Thoyre SM,Estrem HH,Park J,Knafl GJ,Nix B

    更新日期:2017-01-01 00:00:00

  • Acute treatment of critical vascular stenoses with a bioabsorbable magnesium scaffold in infants with CHDs.

    abstract:BACKGROUND:Post-operative severe vascular stenosis and proliferating endothelial tissue lead to severe circulatory disorders and impair organ perfusion. Bioabsorbable magnesium scaffolds may help to overcome these obstructions without leaving obstructing stent material. We analyse their role in the treatment of vascula...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951120000384

    authors: Zartner PA,Schranz D,Mini N,Schneider MB,Schneider K

    更新日期:2020-04-01 00:00:00

  • A family with a new elastin gene mutation: broad clinical spectrum, including sudden cardiac death.

    abstract::Supravalvular aortic stenosis is associated with the Williams-Beuren syndrome, but it also occurs in a non-syndromatic congenital form. An elastin gene mutation of chromosome 7q11.23 is responsible in both cases. The vascular features are identical. These patients have a higher risk of sudden death, particularly when ...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951110001563

    authors: Jakob A,Unger S,Arnold R,Grohmann J,Kraus C,Schlensak C,Stiller B

    更新日期:2011-02-01 00:00:00

  • Percutaneous transcatheter occlusion of the patent arterial duct using the pfm DuctOcclud Coil via a trans-aortic and trans-pulmonary approach.

    abstract::Occlusion using coils is now the treatment of choice for closure of the patent arterial duct. The DuctOcclud (pfm AG, Cologne, Germany) device is a relatively new retrievable coil for such trans-catheter closure. This study expands on previously reported experience with this device, summarizes the advantages of the de...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/s1047951102000793

    authors: Friedberg M,Khoury A,Schwartz Y,Braver Y,Lorber A

    更新日期:2002-10-01 00:00:00

  • Respiratory infection in congenital cardiac disease. Hospitalizations in young children in Spain during 2004 and 2005: the CIVIC Epidemiologic Study.

    abstract:OBJECTIVES:To evaluate the rate of hospitalization for acute respiratory tract infection in children less than 24 months with haemodynamically significant congenital cardiac disease, and to describe associated risk factors, preventive measures, aetiology, and clinical course. MATERIALS AND METHODS:We followed 760 subj...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S104795110700042X

    authors: Medrano C,Garcia-Guereta L,Grueso J,Insa B,Ballesteros F,Casaldaliga J,Cuenca V,Escudero F,de la Calzada LG,Luis M,Luque M,Mendoza A,Prada F,del Mar Rodríguez M,Suarez P,Quero C,Guilera M,CIVIC Study Group from the Span

    更新日期:2007-08-01 00:00:00

  • Abnormal origins of the coronary arteries from the aortic root.

    abstract::Anomalous origin of a coronary artery from the aorta is a potentially serious anomaly that occurs in about 0.1-0.2% of the population. This percentage is small; however, it translates into about 4000 annual births with these anomalies. The clinical presentation of these anomalies is rare, and hence most are and will r...

    journal_title:Cardiology in the young

    pub_type: 杂志文章,评审

    doi:10.1017/S1047951114000250

    authors: Hoffman JI

    更新日期:2014-10-01 00:00:00

  • Edwards valve-in-valve implantation in tricuspid position.

    abstract::We present two cases of percutaneous Sapien XT valve-in-valve implantation in the tricuspid position: a 20-year-old man with severe congenital pulmonary stenosis and percutaneous valvuloplasty, who required surgical implantation of two protheses, pulmonary and tricuspid, and a 12-year-old boy with CHD and a degenerate...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951117000786

    authors: Álvarez-Fuente M,Haas NA,Del Cerro MJ

    更新日期:2017-10-01 00:00:00

  • The prenatal diagnosis of, and short-term outcome for, patients with congenitally corrected transposition.

    abstract::Congenitally corrected transposition is a rare congenital anomaly, with only a few cases diagnosed and reported prenatally even in the largest fetal series. To determine the morphologic features and outcome for the lesion as recognized during fetal life, we reviewed the fetal and postnatal echocardiograms and medical ...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S104795110400304X

    authors: Chiappa E,Micheletti A,Sciarrone A,Botta G,Abbruzzese P

    更新日期:2004-06-01 00:00:00

  • Pregnancy and early post-natal outcomes of fetuses with functionally univentricular heart in a low-and-middle-income country.

    abstract:BACKGROUND:Care of children with functionally univentricular hearts is resource-intensive. OBJECTIVES:To analyse pregnancy and early post-natal outcomes of fetuses with functionally univentricular hearts in the setting of a low-middle-income country. METHODS:A retrospective study was conducted during the period of Ja...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951120002929

    authors: Vaidyanathan B,Vijayaraghavan A,Thomas S,Sudhakar A

    更新日期:2020-12-01 00:00:00

  • Time course of appearance of markers of arrhythmia in patients with tetralogy of Fallot before and after surgery.

    abstract::Sudden death and ventricular tachycardia are known to occur late after correction of tetralogy of Fallot. Abnormal dispersion of the QT interval, ventricular late potentials, and prolongation of the QRS complex, alone or in combination, are useful markers of the risk for such complications. Our present prospective stu...

    journal_title:Cardiology in the young

    pub_type: 杂志文章

    doi:10.1017/S1047951104004020

    authors: Balkhi RA,Beghetti M,Friedli B

    更新日期:2004-08-01 00:00:00