Abstract:
GOAL AND OBJECTIVES:Parkinsonian patients can be classified in two main subgroups: tremor dominant and akinetic-rigid. The aim of this study was to evaluate whether intensive rehabilitation treatment has the same efficacy in the two subtypes. MATERIAL AND METHODS:Patients were classified according to tremor: 65 patients with absence of tremor in "on" and "off" state were assigned to Group_1 and 65 patients with tremor were assigned to Group_2. All patients underwent a 4-week intensive multidisciplinary rehabilitation treatment. The primary outcome measures were: the Unified Parkinson's Disease Rating Scale (UPDRS) II, III, UPDRS akinetic-rigid score and UPDRS tremor score. The secondary outcome measures were: the Berg Balance Scale, 6-minute walking test, self-assessment Parkinson's Disease Disability Scale, Abnormal Involuntary Movement Scale, Freezing of Gait Questionnaire. RESULTS:Patients in Group_1 tended to be more affected than patients in Group_2 by dyskinesias (45% vs 29% p = 0.069) and freezing (46% vs 29%, p = 0.046). Levodopa-equivalent dosages were higher in Group_1 (802 vs 670 mg/day, p = 0.008). Considering the effect of rehabilitation, an homogeneous improvement was observed in all variables in both groups of patients (p < 0.0001). CONCLUSION:Intensive rehabilitation treatment is effective in improving motor performance in both groups. The anatomical and biochemical differences existing between the two subgroups appear to not determine different clinical outcomes.
journal_name
NeuroRehabilitationjournal_title
NeuroRehabilitationauthors
Frazzitta G,Abbruzzese G,Bertotti G,Boveri N,Pezzoli G,Maestri Rdoi
10.3233/NRE-130959subject
Has Abstractpub_date
2013-01-01 00:00:00pages
299-303issue
2eissn
1053-8135issn
1878-6448pii
V643T661414G45V7journal_volume
33pub_type
杂志文章abstract:BACKGROUND:Endocrinopathy, including hypogonadism, is common following traumatic brain injury (TBI). Prior evidence suggests hypogonadism is associated with poorer function. OBJECTIVE:Determine the feasibility, safety, and efficacy of testosterone (T) therapy in hypogonadal men following TBI in acute rehabilitation. ...
journal_title:NeuroRehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.3233/NRE-192992
更新日期:2020-01-01 00:00:00
abstract::We conducted a small pilot study that examined the effect of a 4-week period of unloaded leg cycling on spasticity in individuals with multiple sclerosis (MS). The sample included 22 individuals with MS who were assigned using a quasi-experimental method into either exercise (n = 12) or control (n = 10) conditions. Th...
journal_title:NeuroRehabilitation
pub_type: 临床试验,杂志文章
doi:10.3233/NRE-2009-0486
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Significant results have been shown when an upper limb robot-assisted rehabilitation is delivered to stroke patients. OBJECTIVE:To evaluate the effects of upper limb robot-assisted rehabilitation on motor recovery in stroke patients who underwent a treatment based on a haptic device. METHODS:Thirty-nine st...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-172166
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:The aim of his study was to evaluate the reliability and validity of the Expanded Timed Get-up-and-Go (ETGUG) test in patients with bilateral vestibular loss (BVL). METHODS:21 BVL patients (58 ± 14 years) were recruited and measured twice by two raters. After a one hour break ETGUG was repeated by the first...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-141083
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of motor swallowing exercises on swallowing dynamic, quality of life and swallowing complaints in Parkinson's disease (PD). DESIGN:A before-after trial. SETTING:University Medical Center. PARTICIPANTS:Parkinson's disease patients with dysphagia complaints. INTERVENTIONS:Motor swa...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-130918
更新日期:2013-01-01 00:00:00
abstract::The ability of the adult central nervous system to recover from injury is highly limited. Limiting factors in the repair process appear to be a combination of an inhibiting environment and the restricted intrinsic capacity of the neuron to reactivate its regenerative machinery. Studies using experimental treatments de...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-1998-10204
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Neurorehabilitation technologies such as robot therapy (RT) and transcranial Direct Current Stimulation (tDCS) can promote upper limb (UL) motor recovery after stroke. OBJECTIVE:To explore the effect of anodal tDCS with uni-lateral and three-dimensional RT for the impaired UL in people with sub-acute and ch...
journal_title:NeuroRehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.3233/NRE-151251
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:Bone loss is a common and often debilitating condition that accompanies spinal cord injury. Because bone loss after spinal cord injury is multifactorial, it can be difficult to assess and treat. This process becomes even more complex as secondary conditions associated with aging are introduced. PURPOSE:Th...
journal_title:NeuroRehabilitation
pub_type: 杂志文章,评审
doi:10.3233/NRE-2011-0702
更新日期:2011-01-01 00:00:00
abstract::Delayed post-hypoxic leukoencephalopathy (DPHL) is a demyelinating syndrome characterized by acute onset of neuropsychiatric symptoms days to weeks following apparent recovery from coma after a period of prolonged cerebral hypo-oxygenation. It is diagnosed, after excluding other potential causes of delirium, with a cl...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Persons with moderate to severe TBI are at increased risk for unintentional injury or harm in the home and community; however, there is currently no standard measure of safety risk they face now and in the future. OBJECTIVE:To develop comprehensive and content valid scales and item pools for assessing safet...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-161369
更新日期:2016-06-30 00:00:00
abstract:OBJECTIVE:The aim of this randomized controlled trial was to test the hypothesis that a three-week whole body vibration (WBV) training in addition to a standard rehabilitation program improves walking ability in patients with Multiple Sclerosis (MS). PATIENTS AND METHOD:Sixty patients with definite MS were randomly al...
journal_title:NeuroRehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.3233/NRE-130888
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:The Functional Assessment for Control of Trunk (FACT) was developed to evaluate trunk function after stroke. However, only a few studies used FACT to show functional outcome. OBJECTIVE:This study aimed to validate the FACT predictive ability for functional outcome following stroke and create an English vers...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-201533
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVES:Constraint-induced movement therapy (CIMT) has been demonstrated to be effective in improving hemiparetic upper extremity function in stroke patients, but few studies have been performed to assess orthosis modification. We investigated the effect of the newly designed small orthosis named modified opposition...
journal_title:NeuroRehabilitation
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Many patients who have suffered from a stroke show decreased walking ability, characterized by asymmetric gait. For such patients, the recovery of symmetry in walking is important. OBJECTIVES:The purpose of this study is to investigate the effect of visual feedback with rhythmic auditory cue on treadmill ga...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-162139
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:The minimal number of studies have documented the impact of Vestibular rehabilitation (VR) on the recovery rate of patients with Chronic Unilateral Vestibular Hypofunction (CUVH) and Bilateral Vestibular Hypofunction (BVH). OBJECTIVES:The goal of the study was to show and compare the impact of vestibular re...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-182524
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Considering the extensive neural network of the oculomotor subsystems, traumatic brain injury (TBI) could affect oculomotor control and related reading dysfunction. OBJECTIVE:To evaluate comprehensively the effect of oculomotor-based vision rehabilitation (OBVR) in individuals with mTBI. METHODS:Twelve sub...
journal_title:NeuroRehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.3233/NRE-131025
更新日期:2014-01-01 00:00:00
abstract::Removal of an indwelling catheter and the initiation of intermittent catheterization (IC) has become a standard urological goal over the past decades. While realistic for men it is more difficult for women, mainly due to their anatomical differences and lack of development of a satisfactory external collection device....
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-1994-4407
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVE:to determine the potential impacts of Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF) on the incidence of TBI-related hospitalization in the active duty US Army. METHODS:All active duty Army personnel hospitalized with a TBI diagnosis during fiscal years 2000 through 2006 were identified i...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-2010-0556
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Boxing training including traditional stretching, muscular strength training, and duration training would be considered to be effective for improved functional stretching, dynamic balance, walking speed, and quality of life. OBJECTIVE:We aimed to investigate upper limb function, balance, gait, and quality o...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-161392
更新日期:2017-01-01 00:00:00
abstract::Devastating intracerebral hemorrhagic stroke is rarely encountered in children, but it has a high mortality rate. The case of a 15-year-old boy who survived a major stroke at 40 days old is described. He showed no significant motor or intelligence impairment in adolescence until he was hospitalized for transient left ...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-2012-0785
更新日期:2012-01-01 00:00:00
abstract:GOALS AND OBJECTIVES:The main goal of this study is to evaluate the effect of treadmill exercise on the angiogenesis markers in the striatum (ST) of chronic/progressive parkinsonian mice. MATERIALS AND METHODS:Forty 57BL/6 albino mice were randomly divided into four groups. Sedentary control (SC, n=10), exercise contr...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-2010-0574
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:One of the most interesting emerging medical devices is the medical avatar - a digital representation of the patient that can be used toward myriad ends, the full potential of which remains to be explored. Medical avatars have been instantiated as telemedical tools used to establish a representation of the p...
journal_title:NeuroRehabilitation
pub_type: 杂志文章,评审
doi:10.3233/NRE-203063
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:To determine the effectiveness of a community re-integration exercise initiative on function, mood, participation, and exercise adherence for persons with moderate to severe neurological conditions (stroke, multiple sclerosis, etc.). METHODS:We recruited 29 adults (able to walk at least 3 m with assistance) di...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-141090
更新日期:2014-01-01 00:00:00
abstract::Brain injury can directly and indirectly affect important aspects related to sexuality and sexual function. In this critical review of the literature, traumatic brain injury (TBI) and sexuality are examined. A general review of the concept of sexuality and the neurological correlates of sexual function are proposed as...
journal_title:NeuroRehabilitation
pub_type: 杂志文章,评审
doi:10.3233/NRE-130824
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:This case study was conducted to determine Comprehensive Hand Repetitive Intensive Strengthening Training (CHRIST)-induced morphological changes in the commonly affected extensor carpi radialis (ECR) and triceps brachii (TRI) muscle and associated muscle strength and motor performance in a child with hemipareti...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-2009-0460
更新日期:2009-01-01 00:00:00
abstract::Clients who have experienced a brain injury often are damaged by a third party who is perceived responsible for the consequences of their actions. In the United States, a common method of seeking financial compensation for the injury is to file a personal injury law suit. This article will outline the RAPEL method for...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-1996-7204
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVES:To identify factors that are independently related to interrupted stroke rehabilitation due to acute care transfer or death. METHODS:Medical records of stroke inpatients admitted from 2012 to 2017 were reviewed. Stroke inpatients with interrupted stroke rehabilitation due to acute care transfer or death wer...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-203187
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:To explore the impact of rehabilitation robot training (RRT) on upper limb motor function and daily activity ability in patients with stroke. METHODS:Forty patients meeting the inclusion criteria were randomly divided into the treatment group (TRE) and the control group (CON). Group TRE was trained with an u...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-203130
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:To generate normative data for the Verbal Fluency Tests across 11 countries in Latin America, with country-specific adjustments for gender, age, and education, where appropriate. METHOD:The sample consisted of 3,977 healthy adults who were recruited from Argentina, Bolivia, Chile, Cuba, El Salvador, Guatemal...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-151279
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:The Timed up and go test (TUG), the Five times sit-to-stand test (FTSTS) and the Bed Mobility test (BMT) are widely used in clinical practice for Parkinson Disease (PD). However, no reported studies have evaluated the responsiveness to group physical therapy intervention (GPTI). OBJECTIVE:To verify if TUG, ...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-172379
更新日期:2018-01-01 00:00:00