Priority of lymph node dissection for Siewert type II/III adenocarcinoma of the esophagogastric junction.

Abstract:

OBJECTIVE:The purpose of this study was to clarify the priority of nodal dissection in Siewert types II and III adenocarcinoma of the esophagogastric junction (AEG). METHODS:The priority of nodal dissection was evaluated based on the therapeutic value index calculated by multiplying of the frequency of metastasis to each station and the 5-year survival rate of patients with metastasis to that station. RESULTS:A total of 176 patients (95 type II and 81 type III) were examined. Among the lymph nodes that had a metastatic incidence exceeding 10 %, the stations showing the first to fourth highest index were the paracardial and lesser curvature nodes (Nos. 1, 2, and 3) and the node at the root of the left gastric artery (No. 7) in the total cohort, as well as in each type. The next station was the lower thoracic paraesophageal lymph node (No. 110), followed by the nodes along the proximal splenic artery (No. 11p) in type II, whereas it was the nodes along the proximal splenic artery (No. 11p) followed by the para-aortic nodes (No. 16a2), the nodes at the celiac artery (No. 9), and the nodes around the splenic hilum (No. 10) in type III. CONCLUSIONS:These results suggest that the highest priority nodal stations to be dissected were the paracardial and lesser curvature nodes (Nos. 1, 2, and 3) and the nodes at the root of the left gastric artery (No. 7), regardless of the Siewert subtype, but the subsequent priority was different depending on the subtype.

journal_name

Ann Surg Oncol

authors

Hasegawa S,Yoshikawa T,Rino Y,Oshima T,Aoyama T,Hayashi T,Sato T,Yukawa N,Kameda Y,Sasaki T,Ono H,Tsuchida K,Cho H,Kunisaki C,Masuda M,Tsuburaya A

doi

10.1245/s10434-013-3036-0

subject

Has Abstract

pub_date

2013-12-01 00:00:00

pages

4252-9

issue

13

eissn

1068-9265

issn

1534-4681

journal_volume

20

pub_type

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