Abstract:
IMPORTANCE:One in 88 children in the United States is diagnosed as having autism spectrum disorder. Significant interest centers on understanding the environmental factors that may contribute to autism risk. OBJECTIVE:To examine whether induced (stimulating uterine contractions prior to the onset of spontaneous labor) and/or augmented (increasing the strength, duration, or frequency of uterine contractions with spontaneous onset of labor) births are associated with increased odds of autism. DESIGN, SETTING, AND PARTICIPANTS:We performed an epidemiological analysis using multivariable logistic regression modeling involving the North Carolina Detailed Birth Record and Education Research databases. The study featured 625,042 live births linked with school records, including more than 5500 children with a documented exceptionality designation for autism. EXPOSURES:Induced or augmented births. MAIN OUTCOMES AND MEASURES:Autism as assessed by exceptionality designations in child educational records. RESULTS:Compared with children born to mothers who received neither labor induction nor augmentation, children born to mothers who were induced and augmented, induced only, or augmented only experienced increased odds of autism after controlling for potential confounders related to socioeconomic status, maternal health, pregnancy-related events and conditions, and birth year. The observed associations between labor induction/augmentation were particularly pronounced in male children. CONCLUSIONS AND RELEVANCE:Our work suggests that induction/augmentation during childbirth is associated with increased odds of autism diagnosis in childhood. While these results are interesting, further investigation is needed to differentiate among potential explanations of the association including underlying pregnancy conditions requiring the eventual need to induce/augment, the events of labor and delivery associated with induction/augmentation, and the specific treatments and dosing used to induce/augment labor (e.g., exogenous oxytocin and prostaglandins).
journal_name
JAMA Pediatrjournal_title
JAMA pediatricsauthors
Gregory SG,Anthopolos R,Osgood CE,Grotegut CA,Miranda MLdoi
10.1001/jamapediatrics.2013.2904subject
Has Abstractpub_date
2013-10-01 00:00:00pages
959-66issue
10eissn
2168-6203issn
2168-6211pii
1725449journal_volume
167pub_type
杂志文章相关文献
JAMA Pediatrics文献大全abstract::IMPORTANCE Excessive infant crying is common, distressing, but without proven effective prevention or management options. Probiotics may be a promising solution. OBJECTIVE To examine whether probiotics are effective in the prevention/management of crying ("colic") in infants 3 months or younger. DATA SOURCES A systema...
journal_title:JAMA pediatrics
pub_type: 杂志文章,meta分析,评审
doi:10.1001/jamapediatrics.2013.2572
更新日期:2013-12-01 00:00:00
abstract:Importance:Maternally derived antibodies are a key element of neonatal immunity. Understanding the dynamics of maternal antibody responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy and subsequent transplacental antibody transfer can inform neonatal management as well as ...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2021.0038
更新日期:2021-01-29 00:00:00
abstract:Importance:Firearm injuries are the second leading cause of death among US children and adolescents. Because of the lack of resources allocated to firearm injury prevention during the past 25 years, research has lagged behind other areas of injury prevention. Identifying timely and important research questions regardin...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2019.1494
更新日期:2019-06-10 00:00:00
abstract:Importance:Studies of cranial ultrasonography and early childhood outcomes among cohorts of extremely preterm neonates have linked periventricular-intraventricular hemorrhage and cystic periventricular leukomalacia with adverse neurodevelopmental outcomes. However, the association between nonhemorrhagic ventriculomegal...
journal_title:JAMA pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1001/jamapediatrics.2017.3545
更新日期:2018-01-01 00:00:00
abstract:Importance:Rap artists are among the most recognizable celebrities in the US, serving as role models to an increasingly diverse audience of listeners. Through their lyrics, these artists have the potential to shape mental health discourse and reduce stigma. Objective:To investigate the prevalence and nature of mental ...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2020.5155
更新日期:2020-12-07 00:00:00
abstract:Importance:A total of 25.7 million children in the United States are classified as overweight or obese. Obesity is associated with deficits in executive function, which may contribute to poor dietary decision-making. Less is known about the associations between being overweight or obese and brain development. Objectiv...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2019.4708
更新日期:2020-02-01 00:00:00
abstract:IMPORTANCE:Histamine-2 receptor antagonists (H2RAs) are frequently used in the treatment of gastroesophageal reflux disease (GERD) in children; however, their efficacy and safety is questionable. OBJECTIVE:To systematically review the literature to assess the efficacy and safety of H2RAs in pediatric GERD. EVIDENCE R...
journal_title:JAMA pediatrics
pub_type: 杂志文章,评审
doi:10.1001/jamapediatrics.2014.1273
更新日期:2014-10-01 00:00:00
abstract::OBJECTIVES To determine the effect of modifiable dietary intake variables (current vitamin D supplementation and daily cow's milk intake) on 25-hydroxyvitamin D level in early childhood and to evaluate the relationship between these modifiable dietary factors and other largely nonmodifiable determinants of vitamin D s...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/2013.jamapediatrics.226
更新日期:2013-03-01 00:00:00
abstract:IMPORTANCE:Although cancer remains the most common cause of disease-related death in adolescents and young adults (AYAs) in high-income countries, their overall survival rates continue to increase and now exceed 80% at 5 years in several high-income countries. This has been accomplished through progressive improvements...
journal_title:JAMA pediatrics
pub_type: 杂志文章,评审
doi:10.1001/jamapediatrics.2015.4689
更新日期:2016-05-01 00:00:00
abstract:Importance:Preterm and postterm births are associated with adverse neuropsychiatric outcomes. However, it remains unclear whether variation of gestational age within the 37- to 42-week range of term deliveries is associated with neurodevelopment. Objective:To investigate the association of gestational age at birth (GA...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2020.2991
更新日期:2020-09-21 00:00:00
abstract:Importance:Rapid and accurate diagnosis of late-onset infection in newborn infants could inform treatment decisions and avoid unnecessary administration of antibiotics. Objective:To compare the accuracy of serum C-reactive protein (CRP) with that of microbiological blood culture for diagnosing late-onset infection in ...
journal_title:JAMA pediatrics
pub_type: 杂志文章,meta分析
doi:10.1001/jamapediatrics.2019.5669
更新日期:2020-03-01 00:00:00
abstract:IMPORTANCE:Neonatal hypothermia has been associated with higher mortality and morbidity; therefore, thermal control following delivery is an essential part of neonatal care. Identifying the ideal body temperature in preterm neonates in the first few hours of life may be helpful to reduce the risk for adverse outcomes. ...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2015.0277
更新日期:2015-04-01 00:00:00
abstract:Importance:Caffeine citrate therapy for apnea of prematurity reduces the rates of bronchopulmonary dysplasia, severe retinopathy, and neurodevelopmental disability at 18 months and may improve motor function at 5 years. Objective:To evaluate whether neonatal caffeine therapy is associated with improved functional outc...
journal_title:JAMA pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1001/jamapediatrics.2017.0238
更新日期:2017-06-01 00:00:00
abstract:IMPORTANCE:Behavioral change interventions have demonstrated short-term efficacy in reducing sexually transmitted infection (STI)/human immunodeficiency virus (HIV) risk behaviors; however, few have demonstrated long-term efficacy. OBJECTIVE:To evaluate the efficacy of a telephone counseling prevention maintenance int...
journal_title:JAMA pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1001/jamapediatrics.2014.1436
更新日期:2014-10-01 00:00:00
abstract:IMPORTANCE:Efforts to transform primary care through the medical home model may have limited effectiveness if they do not incorporate families' preferences for different primary care services. OBJECTIVE:To assess parents' relative preferences for different categories of enhanced access services in primary care. DESIG...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2014.3534
更新日期:2015-04-01 00:00:00
abstract:IMPORTANCE:Given the importance of developing healthy eating patterns during early childhood, policies to improve the elementary school food and beverage environments are critical. OBJECTIVE:To examine the association between district and state policy and/or law requirements regarding competitive food and beverages an...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2013.32
更新日期:2013-08-01 00:00:00
abstract:IMPORTANCE:Smaller cerebral volumes at hospital discharge in very preterm (VPT) infants are associated with poor neurobehavioral outcomes. Brain growth from the newborn period to middle childhood has not been explored because longitudinal data have been lacking. OBJECTIVES:To examine the pattern of growth of cerebral ...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2016.0781
更新日期:2016-08-01 00:00:00
abstract:IMPORTANCE:Outcomes associated with use of high-frequency oscillatory ventilation (HFOV) in children with acute respiratory failure have not been established. OBJECTIVE:To compare the outcomes of HFOV with those of conventional mechanical ventilation (CMV) in children with acute respiratory failure. DESIGN, SETTING, ...
journal_title:JAMA pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1001/jamapediatrics.2013.4463
更新日期:2014-03-01 00:00:00
abstract:IMPORTANCE:Short-term impacts of breakfast consumption on diet quality and cognitive functioning have been reported, but more evidence is needed to draw causal inferences about long-term impacts of school breakfast on indicators of school engagement and academic achievement. OBJECTIVE:To estimate the impact of a Break...
journal_title:JAMA pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1001/jamapediatrics.2014.2042
更新日期:2015-01-01 00:00:00
abstract:Importance:Home aeroallergen exposure is associated with increased asthma morbidity in children, yet little is known about the contribution of school aeroallergen exposures to such morbidity. Objective:To evaluate the effect of school-specific aeroallergen exposures on asthma morbidity among students, adjusting for ho...
journal_title:JAMA pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1001/jamapediatrics.2016.2543
更新日期:2017-01-01 00:00:00
abstract::After pediatric injury, transient traumatic stress reactions are common, and about 1 in 6 children and their parents develop persistent posttraumatic stress (PTS) symptoms that are linked to poorer physical and functional recovery. Meta-analytic studies identify risk factors for persistent PTS, including preinjury psy...
journal_title:JAMA pediatrics
pub_type: 杂志文章,评审
doi:10.1001/jamapediatrics.2013.2741
更新日期:2013-12-01 00:00:00
abstract:Importance:Suicide is the second-leading cause of death among adolescents. Sexual minority individuals are at a higher risk of suicide and attempted suicide, but a precise and systematic evaluation of this risk among sexual minority youths has not been documented to our knowledge. Objective:To examine the risk of atte...
journal_title:JAMA pediatrics
pub_type: 杂志文章,meta分析
doi:10.1001/jamapediatrics.2018.2731
更新日期:2018-12-01 00:00:00
abstract:Importance:Nearly 6 million children are reported as allegedly experiencing abuse or neglect in the US annually. Child protection agencies are increasingly turning to automated predictive risk models (PRMs) that mine information found in routinely collected administrative data and estimate a likelihood that an individu...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2020.2770
更新日期:2020-08-03 00:00:00
abstract:IMPORTANCE:Most patients with asthma take fewer than half of prescribed doses of controller medication. Interventions to improve adherence have typically been costly, impractical, and at best only minimally successful. OBJECTIVE:To test a speech recognition (SR) intervention to improve adherence to pediatric asthma co...
journal_title:JAMA pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1001/jamapediatrics.2014.3280
更新日期:2015-04-01 00:00:00
abstract:Importance:Prenatal and neonatal cystic kidney diseases are a group of rare disorders manifesting as single, multiple unilateral, or bilateral cysts or with increased echogenicity of the renal cortex without macroscopic cysts. They may be accompanied by grossly enlarged kidneys, renal oligohydramnios, pulmonary hypopla...
journal_title:JAMA pediatrics
pub_type: 共识发展会议,杂志文章
doi:10.1001/jamapediatrics.2017.3938
更新日期:2018-01-01 00:00:00
abstract:IMPORTANCE:Exchange transfusion is recommended for newborns with total serum bilirubin (TSB) levels thought to place them at risk for cerebral palsy (CP). However, the excess risk for CP among these infants is unknown. OBJECTIVE:To quantify the risks for CP and CP consistent with kernicterus that are associated with h...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2014.3036
更新日期:2015-03-01 00:00:00
abstract:Importance:Sleep is vital to children's biopsychosocial development. Inadequate sleep quantity and quality is a public health concern with an array of detrimental health outcomes. Portable mobile and media devices have become a ubiquitous part of children's lives and may affect their sleep duration and quality. Object...
journal_title:JAMA pediatrics
pub_type: 杂志文章,meta分析,评审
doi:10.1001/jamapediatrics.2016.2341
更新日期:2016-12-01 00:00:00
abstract:Importance:Corporal punishment is a leading risk factor for physical abuse. Strong anecdotal evidence from physicians and other professionals working in child protection suggest that punishment-initiated physical abuse for school-aged children increases after release of report cards. However, no empirical examination o...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2018.4346
更新日期:2019-02-01 00:00:00
abstract:IMPORTANCE:As of 2015, almost half of US states allow medical marijuana, and 4 states allow recreational marijuana. To our knowledge, the effect of recreational marijuana on the pediatric population has not been evaluated. OBJECTIVE:To compare the incidence of pediatric marijuana exposures evaluated at a children's ho...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2016.0971
更新日期:2016-09-06 00:00:00
abstract:Importance:Enamel defects of developmental origin affect up to 38% of schoolchildren and is recognized as a global public health challenge. The impaired enamel formation results in pain owing to hypersensitivity, posteruptive breakdowns, rapid caries progression, and extractions in some cases. The etiology is unknown; ...
journal_title:JAMA pediatrics
pub_type: 杂志文章
doi:10.1001/jamapediatrics.2019.2545
更新日期:2019-08-05 00:00:00