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A representative of the dominant human colonic Firmicutes, Roseburia faecis M72/1, forms a novel bacteriocin-like substance.

Abstract：

:During screening of human gut isolates in search of novel antimicrobials, the butyrate-producing strain Roseburia faecis M72/1 was found to produce an inhibitory substance active against Bacillus subtilis. Partial purification of the antimicrobial was achieved and activity found to be heat labile. Our findings suggest that R. faecis M72/1 produces a proteinaceous inhibitor whose production may be triggered by trypsin in the gastrointestinal tract.

journal_name

Anaerobe

journal_title

Anaerobe

authors

Hatziioanou D,Mayer MJ,Duncan SH,Flint HJ,Narbad A

doi

10.1016/j.anaerobe.2013.07.006

subject

Has Abstract

pub_date

2013-10-01 00:00:00

pages

5-8

eissn

1075-9964

issn

1095-8274

pii

S1075-9964(13)00127-3

journal_volume

23

pub_type

杂志文章

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