My life with adeno-associated virus: a long time spent studying a short genome.

abstract：:Palindromati, the massive host-edited synthetic palindromic contamination found in GenBank, is illustrated and exemplified. Millions of contaminated sequences with portions or tandems of such portions derived from the ZAP adaptor or related linkers are shown (1) by the 12-bp sequence reported elsewhere, exon Xb, 5' CC...

journal_title：DNA and cell biology

authors： Castro-Chavez F

更新日期：2012-02-01 00:00:00

abstract：:We have determined the expression pattern of all 11 human replication-dependent histone H3 genes in three fetal human tissues (bladder, liver, and lung) and in eight human cell lines by RNase protection assay. In the fetal human tissues, all 11 genes were expressed to a varied extent. However, the relative contributio...

journal_title：DNA and cell biology

authors： Koessler H,Doenecke D,Albig W

更新日期：2003-04-01 00:00:00

abstract：:Deer antlers are amazing natural appendages that grow faster than any other known mammalian bone. Antler growth occurs at the tip and is initially cartilage, which is later replaced by bone tissue. However, little is known regarding the precise role of cooperation between cell lineages and functional genes in regulati...

journal_title：DNA and cell biology

authors： Yao B,Zhang M,Liu M,Wang Q,Liu M,Zhao Y

更新日期：2018-01-01 00:00:00

abstract：:We have cloned and sequenced the cDNA corresponding to the rat preproepidermal growth factor (ppEGF) mRNA. The cDNA contained 4,801 nucleotides, similar to that reported for the mouse (4,749 nucleotides) and the human mRNAs (4,871 nucleotides). The predicted protein sequence would contain 1,133 amino acids, smaller th...

journal_title：DNA and cell biology

authors： Saggi SJ,Safirstein R,Price PM

更新日期：1992-07-01 00:00:00

abstract：:Increasing evidence suggested that long noncoding RNAs (lncRNAs) variants may be involved in the progression of various cancers. However, the association of the lncRNAs polymorphisms with the risk for esophagogastric junction adenocarcinoma (EGJA) is still unknown. In this case-control study, we selected two cancer-re...

journal_title：DNA and cell biology

authors： Cao R,Chen Y,Wang J,Chen M,Chen S,Tang W

更新日期：2020-05-01 00:00:00

abstract：:NANOG is a critical homeodomain transcription factor responsible for maintaining embryonic stem cell (ESC) self-renewal and pluripotency. In the present study, we isolated, sequenced, and characterized the NANOG gene in buffalo ESC-like cells. Here, we demonstrated that NANOG mRNA is expressed as multiple isoforms and...

journal_title：DNA and cell biology

authors： Singh N,Sharma R,George A,Singla SK,Palta P,Manik R,Chauhan MS,Singh D

更新日期：2012-05-01 00:00:00

abstract：:Hepatocyte nuclear factor-1alpha (HNF-1alpha) is a homeodomain-containing transcription factor regulating the expression of liver and pancreas-specific genes. Mutations in the HNF-1alpha-encoding gene TCF1 cause maturity-onset diabetes of the young, type 3 (MODY3). These mutations may affect nuclear import or reduce t...

journal_title：DNA and cell biology

authors： Bjørkhaug L,Bratland A,Njølstad PR,Molven A

更新日期：2005-11-01 00:00:00

abstract：:DNA methylation plays an essential role in carcinogenesis. Promoter hypermethylation can result in transcriptional silencing of specific genes, such as tumor suppressors. Thus far, few reports have investigated the effect of curcumin, an active component of the perennial herb Curcuma longa, on DNA methylation. In the ...

journal_title：DNA and cell biology

authors： Wu B,Yao X,Nie X,Xu R

更新日期：2013-06-01 00:00:00

abstract：:Age-related macular degeneration (AMD) is a disease with multifactorial etiology characterized by irreversible loss of central visual acuity. The discovery of susceptive single-nucleotide polymorphisms (SNPs) has progressed our understanding of AMD. Complement factor H (CFH) gene Y402H polymorphism and high-temperatur...

journal_title：DNA and cell biology

authors： Soysal Y,Inan UÜ,Küsbeci T,Imirzalioğlu N

更新日期：2012-03-01 00:00:00

abstract：:Polyhomeotic is a member of the Polycomb group of genes. The products of this group are chromatin-associated proteins that act together as multimeric complexes. These proteins are required for the maintenance of target gene repression in a permanent and heritable manner during development. In order to better understan...

journal_title：DNA and cell biology

authors： Netter S,Faucheux M,Théodore L

更新日期：2001-08-01 00:00:00

abstract：:The sugars will eventually be exported transporters (SWEET) gene family is a glycoprotein gene family that can regulate the transport of sugar in plants and plays an important role in plant growth and development, as well as in response to environmental stress. In this study, Kentucky bluegrass (cv. Baron) seedlings w...

journal_title：DNA and cell biology

authors： Zhang R,Niu K,Ma H

更新日期：2020-09-01 00:00:00

abstract：:Genes involved in the production of nitric oxide (NO) have been suggested as genetic factors for migraine. It has been studied whether polymorphisms in the genes encoding for different types of NO synthase (NOS) could be involved in the liability to migraine; however, most studies yield negative results. The pentanucl...

journal_title：DNA and cell biology

authors： Jia S,Ni J,Chen S,Jiang Y,Dong W,Gao Y

更新日期：2011-02-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) is known for its ability to infect immune cells, including T-cells and macrophages. The 96-amino acid Vpr, a virion-associated protein, is essential for viral replication in monocytes/macrophages and increases viral replication in primary and established T-cell lines. The Vp...

journal_title：DNA and cell biology

authors： Muthumani K,Montaner LJ,Ayyavoo V,Weiner DB

更新日期：2000-03-01 00:00:00

abstract：:Host cell-derived danger-associated molecular patterns (DAMPs), such as the hemoglobin (Hb) can interact with the innate immune system either directly or through binding to pathogen-associated molecular patterns (PAMPs). Hemolysis occurs under various pathological conditions, leading to hemoglobinemia. In the extracel...

journal_title：DNA and cell biology

authors： Lee SK,Ding JL

更新日期：2013-02-01 00:00:00

abstract：:In a systematic approach to identify interferon-gamma (IFN-gamma)-regulated host effector molecules, we found several members of the 65 kDa guanylate-binding proteins (GBPs) highly upregulated. During extensive characterization of these guanosine triphosphatases (GTPases), we identified discrepancies between the clone...

journal_title：DNA and cell biology

authors： Konermann C,Kresse A,Beuter-Gunia C,Würthner J,Degrandi D,Pfeffer K,Beer S

更新日期：2007-12-01 00:00:00

abstract：:The prototypic member of the transforming growth factor beta family is TGFbeta1, which is known to be important in extracellular matrix production, cell proliferation, and cell differentiation. Specifically in the pituitary lactotroph, TGFbeta1 inhibits prolactin (PRL) peptide secretion, PRL mRNA levels, and PRL gene ...

journal_title：DNA and cell biology

authors： Farrow KN,Gutierrez-Hartmann A

更新日期：1999-11-01 00:00:00

abstract：:We cloned and sequenced a 1378 bp BamHI satellite DNA fraction from the water buffalo Bubalus bubalis and have studied its expression in different tissues. The GC-rich sequences of the resultant contig pDS5 crosshybridize only with bovid DNA and are not conserved evolutionarily. Typing of buffalo genomic DNA using pDS...

journal_title：DNA and cell biology

authors： Chattopadhyay M,Gangadharan S,Kapur V,Azfer MA,Prakash B,Ali S

更新日期：2001-09-01 00:00:00

abstract：:Quantitative determination of T-cell receptor (TCR) V beta expression is necessary to define the changes in TCR-V beta subfamily expression that occur during T-cell maturation and selection and to detect alterations of the TCR-V beta repertoire that may be associated with human diseases. Here we describe and validate ...

journal_title：DNA and cell biology

authors： Duchmann R,Strober W,James SP

更新日期：1993-04-01 00:00:00

abstract：:Dilated cardiomyopathy (DCM) is a common type of cardiomyopathy. The pathogenesis of DCM remains unclear and involves varied genes. AXIN1 is a crucial gene in regulating various functions in cells, it encodes protein Axin1, which regulates the assembly and disassembly of β-catenin destruction complex. In addition, Wnt...

journal_title：DNA and cell biology

authors： Li K,Zhong Y,Peng Y,Zhou B,Wang Y,Li Q,Zhang Y,Song H,Rao L

更新日期：2019-05-01 00:00:00

abstract：:It is well known that the positively charged polyamines have a DNA-stabilizing function and that polyamine depletion alters chromatin function. We have previously shown that polyamine depletion causes an S phase prolongation, and others have shown that there is an accumulation of Okazaki-like fragments in polyamine-de...

journal_title：DNA and cell biology

authors： Johansson VM,Oredsson SM,Alm K

更新日期：2008-09-01 00:00:00

abstract：:Duchenne muscular dystrophy is the most common and severe form of progressive muscular dystrophy. Previous results showed an increased survival in double knockout mice (dko) when treated with adipose-derived CD146+ cells. In this study, we analyzed the effect of CD146+ cells compared to mesenchymal stem/stromal cells ...

journal_title：DNA and cell biology

authors： Gomes JP,Coatti GC,Valadares MC,Assoni AF,Pelatti MV,Secco M,Zatz M

更新日期：2018-09-01 00:00:00

abstract：:Aberrant neutrophil (PMN) infiltration of the intestinal mucosa is a hallmark of inflammatory bowel diseases, including Crohn's disease and ulcerative colitis. While the genotoxic function of PMNs and its implications in carcinogenesis have been primarily associated with oxidative stress, recent work by Butin-Israeli ...

journal_title：DNA and cell biology

authors： Bui TM,Sumagin R

更新日期：2019-08-01 00:00:00

abstract：:Extracellular vesicles classified as exosomes, microvesicles, or apoptotic bodies based on size are shed from most cells under normal as well as pathological conditions. They are released into the surrounding milieu, including plasma, urine, saliva, and tissues. Exosomes are highly enriched in microRNAs (miRs), which ...

journal_title：DNA and cell biology

authors： Pulliam L,Gupta A

更新日期：2015-07-01 00:00:00

abstract：:The ras oncogene exists in a variety of human cancers, including carcinomas of bladder, breast, colon, kidney, liver, lung, ovary, pancreas, and stomach. The ras genes acquire transforming activity either by enhanced expression or by a single point mutation. A single base-pair mutation at specific sites within ras gen...

journal_title：DNA and cell biology

authors： Chien CH,Chow SN

更新日期：1993-09-01 00:00:00

abstract：:Uterine corpus endometrial carcinoma (UCEC) is one of the leading causes of death from gynecological cancer due to the high recurrence rate. A recent study indicated that molecular biomarkers can enhance the recurrence prediction power if they were integrated with clinical information. In this study, we attempted to i...

journal_title：DNA and cell biology

authors： Wang P,Zeng Z,Shen X,Tian X,Ye Q

更新日期：2020-04-01 00:00:00

abstract：:This study aimed to investigate the expression and clinical significance of chemokine-like factor-like MARVEL transmembrane domain-containing family member 2 (CMTM2) in hepatocellular carcinoma (HCC) tissues. Bioinformatics analysis showed that CMTM2 was downregulated in HCC tissues and correlated with vascular invasi...

journal_title：DNA and cell biology

authors： Guo X,Zhang S,Tan S,Bei C,Zhang H,Zhu X,Qiu X

更新日期：2020-04-01 00:00:00

abstract：:At supramolecular resolution, DNA synthesis begins at preferred replication origins in the chromosomes of metazoan cells. To characterize one of these origins in detail, the initiation of replication was examined in the HeLa c-myc origin. Polymerase chain reaction (PCR) amplification of size-fractionated nascent chrom...

journal_title：DNA and cell biology

authors： Trivedi A,Waltz SE,Kamath S,Leffak M

更新日期：1998-10-01 00:00:00

abstract：:The human immunodeficiency virus type I (HIV-1) accessory protein Vpr has been associated with the induction of programmed cell death (apoptosis) and cell-cycle arrest. Studies have shown the apoptotic effect of Vpr on primary and established cell lines and on diverse tissues including the central nervous system (CNS)...

journal_title：DNA and cell biology

authors： Cheng X,Mukhtar M,Acheampong EA,Srinivasan A,Rafi M,Pomerantz RJ,Parveen Z

更新日期：2007-02-01 00:00:00

abstract：:Six identical cDNA clones corresponding to an RNA of 1685 nucleotides that is enriched in mouse sperm compared with testis were isolated from a mouse testis cDNA library. The sequence of these clones corresponds to the 16S mitochondrial RNA plus an inverted repeat of 120 bp covalently joined to the 5' end of the RNA. ...

journal_title：DNA and cell biology

authors： Villegas J,Zárraga AM,Muller I,Montecinos L,Werner E,Brito M,Meneses AM,Burzio LO

更新日期：2000-09-01 00:00:00

abstract：:The polB gene encodes DNA polymerase II in Escherichia coli. The nucleotide sequence shows an open reading frame of 2,304 nucleotides coding for a protein of 88 kD. The protein initiation signal is preceded by a lexA box lying 2 nucleotides from the termination signal of araD, and begins with GUG 75 nucleotides after ...

journal_title：DNA and cell biology

authors： Chen H,Sun Y,Stark T,Beattie W,Moses RE

更新日期：1990-11-01 00:00:00