Mechanisms of gut barrier failure in the pathogenesis of necrotizing enterocolitis: Toll-like receptors throw the switch.

abstract：:For most children, cancer has become a curable disease. With this increased survival, the late effects of the diagnosis of cancer and its therapy have assumed increased importance for these children. Multiple late effects of essentially all organ systems have been described in selected groups of survivors. These may b...

journal_title：Seminars in pediatric surgery

authors： Neglia JP

更新日期：1993-02-01 00:00:00

abstract：:Management strategies for infants with very low birth weight (VLBW) who have abdominal wall defects essentially are the same as for those in larger infants. The authors favor primary closure in infants with gastroschisis, and have achieved this goal in 91% of infants since 1985. Treatment of infants with omphalocele i...

journal_title：Seminars in pediatric surgery

authors： Reynolds M

更新日期：2000-05-01 00:00:00

abstract：:The neurologically or immunologically impaired child suspected of having an acute abdomen presents a formidable challenge. However, a thorough understanding of the underlying pathophysiology of the disease on the normal host response to an intraabdominal disease permits early recognition and initiation of treatment. C...

journal_title：Seminars in pediatric surgery

authors： Bensard DD,Haase GM

更新日期：1997-05-01 00:00:00

abstract：:Gastrointestinal bleeding in infants and children can be quite alarming and anxiety-provoking for parents and caregivers alike. In most cases the cause is benign, and the course self-limited. However, in the patient with significant bleeding, an aggressive diagnostic approach is warranted. The differential diagnosis c...

journal_title：Seminars in pediatric surgery

authors： Brown RL,Azizkhan RG

更新日期：1999-11-01 00:00:00

abstract：:The care provided in the postanesthesia recovery unit has become much more sophisticated in recent years. We address what type of care should be provided and what equipment is required to provide such care in the present day pediatric postanesthesia care unit. In this regard a wide variety of potential postanesthetic ...

journal_title：Seminars in pediatric surgery

authors： Bryant LD,Dierdorf SF

更新日期：1992-02-01 00:00:00

abstract：:In the United States nearly 2 million people are burned every year; about 100,000 burns are moderate to severe and require hospitalization and about 5,000 deaths occur because of burns. The overall improvement in mortality and outcome of patients with severe burn trauma over the last decades can be attributed to the f...

journal_title：Seminars in pediatric surgery

authors： Herndon DN,Spies M

更新日期：2001-02-01 00:00:00

abstract：:Nephron-sparing surgery (NSS) is the treatment of choice for children with bilateral Wilms' tumor (WT), or with WT on a single kidney, or with WT and a disease of the contralateral kidney, or with benign kidney tumor. NSS is a reasonable alternative to nephrectomy in children at risk of metachronous WT, including chil...

journal_title：Seminars in pediatric surgery

authors： Cozzi DA,Zani A

更新日期：2006-02-01 00:00:00

abstract：:Myelomeningocele (MMC) is a common birth defect that is associated with significant lifelong morbidity. Little progress has been made in the postnatal surgical management of the child with spina bifida. Postnatal surgery is aimed at covering the exposed spinal cord, preventing infection, and treating hydrocephalus wit...

journal_title：Seminars in pediatric surgery

authors： Adzick NS,Walsh DS

更新日期：2003-08-01 00:00:00

abstract：:When a female is born and has only a single perineal orifice on the newborn clinical examination, a diagnosis of cloaca type of anorectal malformation is made. Along with associated malformations which may initiate the ordering of radiologic imaging, there are a finite number of radiologic tests that are performed to ...

journal_title：Seminars in pediatric surgery

authors： Kraus SJ

更新日期：2016-04-01 00:00:00

abstract：:Obesity affects 50% of adults and 18% of children in the USA. It has wide-ranging comorbidities with clinical, psychosocial, and economic ramifications. Obesity refers to a condition of excess body fat. The basis for weight gain is a fundamental imbalance between caloric intake and output, but individual variation bas...

journal_title：Seminars in pediatric surgery

authors： Browne AF,Inge T

更新日期：2009-08-01 00:00:00

abstract：:The unfavorable prognosis of congenital hyperinsulinism (CHI) can be avoided if the patients are treated with high-dose glucose infusions and timely surgical intervention. Circumscribed foci used to be identified by selective percutaneous pancreatic vein catheterization and determination of the insulin level. Fluorine...

journal_title：Seminars in pediatric surgery

authors： Mohnike W,Barthlen W,Mohnike K,Blankenstein O

更新日期：2011-02-01 00:00:00

abstract：:Gastrointestinal motility disorders can develop in neurologically impaired children and those with congenital malformations of the gut. It is characterized by moderate to severe abdominal pain, vomiting, and failure to thrive. Antral dysmotility after fundoplication and increased sympathetic over activity are 2 factor...

journal_title：Seminars in pediatric surgery

authors： Carachi R,Currie JM,Steven M

更新日期：2009-11-01 00:00:00

abstract：:Identification of CDH infant populations at high risk for mortality postnatally may help to develop targeted care strategies, guide discussions surrounding palliation and contribute to standardizing reporting and benchmarking, so that care strategies at different centers can be compared. Clinical prediction rules are ...

journal_title：Seminars in pediatric surgery

authors： Daodu O,Brindle ME

更新日期：2017-06-01 00:00:00

abstract：:The field of intestinal transplantation has experienced dramatic growth since the first reported cases 3 decades ago. Improvements in operative technique, donor assessment and immunosuppressive protocols have afforded children who suffer from life-threatening complications of intestinal failure a chance at long-term s...

journal_title：Seminars in pediatric surgery

authors： Soltys KA,Bond G,Sindhi R,Rassmussen SK,Ganoza A,Khanna A,Mazariegos G

更新日期：2017-08-01 00:00:00

abstract：:Pediatric germ cell tumors represent a diverse group of tumors that present from in utero through adolescence at many nongonadal locations, from the neck to the sacrococcygeal region. Surgical resection remains the central element of management, and accurate surgical staging is essential to properly ascertain the corr...

journal_title：Seminars in pediatric surgery

authors： Rescorla FJ

更新日期：2012-02-01 00:00:00

abstract：:Blunt cerebrovascular injury in children is an uncommon occurrence that if missed and left untreated can result in devastating long-term neurologic consequences. Diagnosis can be readily obtained by a computed tomographic angiogram of the head and neck. If confirmed, treatment with antithrombotic therapy dramatically ...

journal_title：Seminars in pediatric surgery

authors： Fenton SJ,Bollo RJ

更新日期：2017-02-01 00:00:00

abstract：:Improvements in parenteral nutrition and supportive therapy have led to a growing population of patients who survive for prolonged periods with short bowel syndrome. Definitive treatment for these patients requires innovative therapy based on a sound knowledge of small intestinal physiology and adaptation. Current und...

journal_title：Seminars in pediatric surgery

authors： Collins JB,Georgeson KE,Vicente Y,Kelly DR,Figueroa R

更新日期：1995-02-01 00:00:00

abstract：:Traditionally, pediatric surgical education consisted of exposure to patients, textbooks, lectures, team-based education, congresses, and workshops. Over the last decades, however, new information technology (IT) and the internet revolutionized the sharing of information and communication. IT has become relevant in pa...

journal_title：Seminars in pediatric surgery

authors： Ure B,Zoeller C,Lacher M

更新日期：2015-06-01 00:00:00

abstract：:Pediatric interventional radiology offers new treatment options not possible a few years ago. Interventional radiologists treat not only certain causes of hemorrhage but also symptomatic arteriovenous malformations, renovascular hypertension, and portal hypertension. Interventionalists help maintain liver and renal tr...

journal_title：Seminars in pediatric surgery

authors： Iglesia KA,Fellows KE

更新日期：1994-05-01 00:00:00

abstract：:This article discusses how to investigate various surgical causes of vomiting. Particular emphasis is placed on plain radiographic, ultrasound, and contrast study findings. The article touches upon nineteen different diseases, and encompasses diseases found in neonates to adolescents. ...

journal_title：Seminars in pediatric surgery

authors： Maclennan AC

更新日期：2003-11-01 00:00:00

abstract：:Neonatal surgery is recognized as an independent discipline in general surgery, requiring the expertise of pediatric surgeons to optimize outcomes in infants with surgical conditions. Survival following neonatal surgery has improved dramatically in the past 60 years. Improvements in pediatric surgical outcomes are in ...

journal_title：Seminars in pediatric surgery

authors： Escobar MA Jr,Caty MG

更新日期：2016-12-01 00:00:00

abstract：:Gene transfer to the tracheobronchial tree has been an active area of investigation since the discovery of the genetic defect in the cystic fibrosis transmembrane conductance regulator over two decades ago. Cystic fibrosis (CF) is the most common lethal monogeneic disorder for which there is no cure short of lung tran...

journal_title：Seminars in pediatric surgery

authors： Keswani SG,Crombleholme TM

更新日期：2004-02-01 00:00:00

abstract：:Central venous catheters (CVC) are commonplace in the management of critically ill patients and serve a variety of purposes. Venous access is important for the administration of fluid and medications as well as blood procurement needed for lab analyses. However, not every critically ill patient requires a CVC. This ar...

journal_title：Seminars in pediatric surgery

authors： Jamshidi R

更新日期：2019-02-01 00:00:00

abstract：:Palliative care is now a core component of pediatric care for children and families who are confronting serious illness with a low likelihood of survival. Pediatric surgeons, in partnership with pediatric palliative care teams, can play a pivotal role in assuring that these patients receive the highest possible qualit...

journal_title：Seminars in pediatric surgery

authors： Feudtner C,Blinman TA

更新日期：2013-08-01 00:00:00

abstract：:Management of pediatric intestinal failure has evolved in recent decades, with improved survival since the advent of specialized multidisciplinary intestinal failure centers. Though sepsis and intestinal failure associated liver disease still contribute to mortality, we now have growing data on the long-term outcomes ...

journal_title：Seminars in pediatric surgery

authors： Fullerton BS,Hong CR,Jaksic T

更新日期：2017-10-01 00:00:00

abstract：:Open spina bifida or myelomeningocele (MMC) is a common birth defect that is associated with significant lifelong morbidity. Little progress has been made in the postnatal surgical management of the child with spina bifida. Postnatal surgery is aimed at covering the exposed spinal cord, preventing infection, and treat...

journal_title：Seminars in pediatric surgery

authors： Adzick NS

更新日期：2013-02-01 00:00:00

abstract：:Slipping rib syndrome (SRS) is an under-diagnosed cause of intermittent, yet often debilitating lower rib and abdominal pain. SRS is caused by a hypermobility of the anterior false ribs that allows the 8th-10th ribs to slip or click as the cartilaginous rib tip abuts or slips under the rib above. Pain occurs from impi...

journal_title：Seminars in pediatric surgery

authors： McMahon LE

更新日期：2018-06-01 00:00:00

abstract：:The outcome for children with congenital enteropathies or massive surgical resections has improved significantly over the past two decades. Advances in understanding of the pathophysiology of intractable diarrhea and of the mutations causing many of the congenital enteropathies have enabled initiation of preventive me...

journal_title：Seminars in pediatric surgery

authors： Kocoshis SA

更新日期：2010-02-01 00:00:00

abstract：:An examination of and recommendations regarding the approval process for medical devices are presented. The typical pathways and hurdles laid out by the Federal Food and Drug Administration (FDA) are discussed, and options for marketing and use of medical devices are addressed. The first step in the regulatory process...

journal_title：Seminars in pediatric surgery

authors： Connor JA

更新日期：2006-11-01 00:00:00

abstract：:Hypertrophic pyloric stenosis (HPS) is a common condition affecting infants that presents with progressive projectile nonbilious vomiting. The pyloric portion of the stomach becomes abnormally thickened and manifests as gastric outlet obstruction. The cause is unknown. Pyloromyotomy remains the standard of treatment a...

journal_title：Seminars in pediatric surgery

authors： Aspelund G,Langer JC

更新日期：2007-02-01 00:00:00