Pediatric intestinal transplantation.

Abstract:

:The field of intestinal transplantation has experienced dramatic growth since the first reported cases 3 decades ago. Improvements in operative technique, donor assessment and immunosuppressive protocols have afforded children who suffer from life-threatening complications of intestinal failure a chance at long-term survival. As experience has grown, newer diseases, with more systemic manifestations have arisen as potential indications for transplant. After discussing the historical developments of intestinal transplant as a backdrop, this review focuses on the specific pre-operative indications for transplant as well as the great success that intestinal rehabilitation has witnessed over the past decade. A detailed discussion of evolution of immunosuppressive strategies is followed a general review of the common infectious complications experienced by children after intestinal transplant as well as the current long- and short-term results, including a section on new research on the quality of life in this challenging population of patients.

journal_name

Semin Pediatr Surg

authors

Soltys KA,Bond G,Sindhi R,Rassmussen SK,Ganoza A,Khanna A,Mazariegos G

doi

10.1053/j.sempedsurg.2017.07.007

subject

Has Abstract

pub_date

2017-08-01 00:00:00

pages

241-249

issue

4

eissn

1055-8586

issn

1532-9453

pii

S1055-8586(17)30075-6

journal_volume

26

pub_type

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