Abstract:
AIM:Skeletal muscle loss is a common feature of aging, and is associated with unfavorable outcomes. Although several indexes of skeletal muscle mass measurement have been developed, the most optimal index for sarcopenia diagnosis among Asian populations has remained unclear. The present study aimed to evaluate the relationship between skeletal muscle mass and physical performance among community-dwelling people in Taiwan. METHODS:Data of the I-Lan Longitudinal Aging Study (ILAS) were retrieved for study. Comparisons between demographic profiles, physical performance and skeletal muscle mass (measured by dual-energy X-ray absorptiometry) were carried out. Skeletal muscle mass expressed by lean body mass divided by squared height (LBM/ht(2) ), appendicular muscle mass divided by squared height (ASM/ht(2) ) and percent skeletal muscle index (SMI%) were compared between measurements of physical performance. RESULTS:Overall, the data of 532 participants (mean age 64.6 ± 9.5 years, male 53.0%) were retrieved for analysis. Age was associated with poorer physical performance, and decreased ASM/ht(2) and LBM/ht(2) , but not SMI%. Skeletal muscle mass (SMI%) was less significantly related to slow walking speed than ASM/ht(2) in men. In women, all three muscle indexes showed no significant association between slow walking speed. In contrast, low handgrip strength was strongly associated with decreased skeletal muscle mass (measured by ASM/ht(2) and LBM/ht(2) , but not SMI%) in both men and women. CONCLUSIONS:Skeletal muscle mass was significantly associated with handgrip strength along with aging, but the association of skeletal muscle mass and walking speed was less significant. In sarcopenia diagnosis among Asian populations, ASM/ht(2) should be the most suitable index for skeletal muscle mass measurements, and physical performance should be measured universally beyond measurements of skeletal muscle mass.
journal_name
Geriatr Gerontol Intjournal_title
Geriatrics & gerontology internationalauthors
Liu LK,Lee WJ,Liu CL,Chen LY,Lin MH,Peng LN,Chen LKdoi
10.1111/ggi.12040subject
Has Abstractpub_date
2013-10-01 00:00:00pages
964-71issue
4eissn
1444-1586issn
1447-0594journal_volume
13pub_type
杂志文章abstract:AIM:This study analyzed the trend of gender gaps in life expectancy (GGLE) in Japan between 1947 and 2010, and explored the correlations of GGLE with gender mortality ratio and social development indices. METHODS:Using GGLE and social indices data collected from the official websites, we carried out trends analysis of...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12001
更新日期:2013-07-01 00:00:00
abstract:AIM:To examine the effects of a multifactorial intervention on frailty and functional health among community-dwelling older adults, a 6-month randomized, controlled, cross-over trial was carried out within the Hatoyama Cohort Study. METHODS:A total of 77 pre-frail or frail older adults (mean age 74.6 years) were rando...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章,随机对照试验
doi:10.1111/ggi.13016
更新日期:2017-11-01 00:00:00
abstract:AIM:To investigate the prevalence and risk factors of delirium in an extended care unit, the persistence of delirium and 3-month outcome. METHOD:Patients aged >65 years were recruited. Basic demographic data, medical comorbidity using the Charlson Comorbidity Index, pre-existing cognitive impairment using the informan...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12521
更新日期:2016-05-01 00:00:00
abstract:AIM:The Community Commitment Scale was developed in Japan to measure communities' ability to prevent older adults' social isolation, including socializing and belonging in the community. We translated the scale into Korean (the Community Commitment Scale-Korean version [CCS-K]), and determined its internal consistency,...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13249
更新日期:2018-05-01 00:00:00
abstract:AIM:To examine the association between depressive symptoms and all-cause mortality in a population-based prospective study. METHODS:Data from the 2008 baseline and 2011 follow-up assessments of the Living Profiles of Older People Survey involving 14 976 Korean adults aged ≥60 years (59% women) were used. Depressive sy...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13270
更新日期:2018-06-01 00:00:00
abstract:AIMS:We aimed to investigate whether older age leads to limitations in the starting dose of imatinib in daily treatment of chronic myeloid leukemia, and to determine the compliance of elderly patients with tyrosine kinase inhibitors (TKI) therapy. METHODS:Data including the clinical characteristics, therapeutic outcom...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章,多中心研究
doi:10.1111/ggi.12341
更新日期:2015-06-01 00:00:00
abstract:AIM:We propose a simple method to measure knee extensor muscle strength using a single-legged vertical squat. The purpose of the present study was to assess the validity of this method in comparison with standard methods of measurement. METHODS:A total of 30 healthy adults (mean age 22 years) and 28 healthy older indi...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13299
更新日期:2018-07-01 00:00:00
abstract:AIM:The present study investigated the status of potentially harmful drug-drug interactions (PHDI) in older adults, to obtain insight into factors that influence the risk of PHDI. METHODS:The present study included Korean people aged ≥65 years who were prescribed one or more drugs included in the list of PHDI under th...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13495
更新日期:2018-09-01 00:00:00
abstract:AIM:To determine if hospital treatment in residential care facilities, led by a geriatric team, might be a viable alternative to inpatient admission for selected patients. METHODS:Case series with a new intervention were compared with historical controls receiving the conventional treatment. Treatment in residential c...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/j.1447-0594.2012.00910.x
更新日期:2013-04-01 00:00:00
abstract:AIM:This cross-sectional study examined whether sleep duration and excessive daytime sleepiness (EDS) were associated with social frailty in community-dwelling older people. METHODS:A total of 4427 community-dwelling older people (51.4% women, mean age 71.9 years) who met the entry criteria were included in this study...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13734
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVES:The aim of the present study was to analyze geriatric oral health predicaments in India. Specifically, to assess the oral health status and treatment needs among the geriatric population attending health camps in New Delhi, Northern India. METHODS:The sample size for the cross-sectional study comprised of 2...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12434
更新日期:2016-01-01 00:00:00
abstract:AIM:To investigate the correlation between handgrip strength and performance of knee flexor and extensor muscles determined using an isokinetic dynamometer in community-dwelling elderly women. METHODS:This was a cross-sectional study. Sample selection for the study was made by convenience, and 221 (71.07 ± 4.93 years)...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章,多中心研究
doi:10.1111/ggi.12077
更新日期:2014-01-01 00:00:00
abstract:AIM:The aim of this study was to develop the Korean Anticholinergic Burden Scale through assessment of previously developed tools, a literature review and a modified Delphi process. METHODS:We carried out a systematic review to identify previously published anticholinergic burden tools. A composite medication list was...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13680
更新日期:2019-07-01 00:00:00
abstract:AIM:Home medical care for older adults with chronic conditions is becoming an increasing important issue in Japan. We need to support long-term medical care at home and avoid unplanned hospitalizations, which can adversely affect activities of daily living and quality of life. In this study, we investigated whether swa...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13753
更新日期:2019-10-01 00:00:00
abstract:AIM:To clarify the factors associated with loss of independence multidimensionally over a 3-year period among community-dwelling older adults. METHODS:The survey was exclusively carried out by the local government for people aged >65 years who were independent at baseline living in H-City, a mid-sized urban city in Ja...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13209
更新日期:2018-03-01 00:00:00
abstract:AIM:We investigated whether mental stress-induced blood pressure elevation was related to cognitive function in the elderly, and further examined the effects of the dual-type calcium channel blocker, cilnidipine, on stress induced hypertension in subjects with mild cognitive impairment. METHODS:In study I, 39 consecut...
journal_title:Geriatrics & gerontology international
pub_type: 临床试验,杂志文章
doi:10.1111/j.1447-0594.2008.00482.x
更新日期:2008-12-01 00:00:00
abstract:AIM:Heredity plays an important role in the pathogenesis of Alzheimer's disease (AD) especially for single-nucleotide polymorphism (SNPs) of susceptible genes, which is one of the significant factors in the pathogenesis of AD. The SNPs of BIN1 rs744373, BIN1 rs7561528 and GAB2 rs2373115 are associated with AD in Asian ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.14109
更新日期:2020-12-16 00:00:00
abstract:AIM:To evaluate the prevalence of potentially inappropriate prescribing (PIP), as defined by the internationally validated Screening Tool of Older Person's Prescriptions (STOPP) criteria, in 12 months before and after initiation of medicines for dementia. METHODS:A retrospective cohort study was carried out involving ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13686
更新日期:2019-07-01 00:00:00
abstract:AIM:To evaluate the association between the amount and frequency of alcohol consumption and incident dementia in older Japanese adults using large sample size data over a long follow-up period. METHODS:This was a retrospective cohort study carried out in Japan. A total of 53 311 older adults were followed from 2008 to...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13694
更新日期:2019-08-01 00:00:00
abstract:AIM:The present study examined the association between vision, fear of falling and fear-related activity restriction, and assessed the effect of vision on the relationship between fear of falling and mobility, using data from a nationally representative sample of community-dwelling adults aged ≥ 50 years. METHODS:Part...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12174
更新日期:2014-10-01 00:00:00
abstract::Bilateral patellae fractures represent a rare entity, accounting for approximately 2.9% of all lesions interesting in this anatomical district. In most cases found in the published work, they are described as stress fractures or as complications of chronic diseases such as osteoporosis, renal failure and secondary hyp...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/j.1447-0594.2008.00447.x
更新日期:2008-03-01 00:00:00
abstract:AIM:Low alanine aminotransferase (ALT) level is associated with frailty in the older adult population. We investigated the usefulness of ALT in predicting low muscle strength among older patients with diabetes. METHODS:We included 550 men aged ≥50 years and 525 postmenopausal women. All participants had diabetes, and ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13868
更新日期:2020-04-01 00:00:00
abstract:AIM:The enteric nervous system degenerates gradually with age, and α-synuclein (α-syn) is a suitable marker of enteric nervous system degeneration, which is intimately related with endoplasmic reticulum stress and unfolded protein response (UPRER ). Saponins from Panax japonicus (SPJ) have obvious protective effects on...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13882
更新日期:2021-01-01 00:00:00
abstract:AIM:Older adults often present with several comorbidities, including sarcopenia. However, the prevalence of sarcopenia and its associations with other comorbidities in hospitalized older adults are unknown. The present study aimed to determine the prevalence of sarcopenia, and its associations with other comorbidities ...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12825
更新日期:2017-07-01 00:00:00
abstract:AIM:The purpose of the present study was to investigate the injury types and medical utilization profiles of veterans in emergency department visits by using big data from the National Health Insurance program in Taiwan. METHOD:We used the outpatient prescriptions and treatment records between 1997 and 2010 of veteran...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12620
更新日期:2016-12-01 00:00:00
abstract:AIM:The relationship between support at home and rehospitalization has not been extensively studied until now. In particular, little is known about the impact of being assisted by migrant care workers (MCW) and rehospitalization. We aimed at investigating such a relationship in a population of older patients discharged...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12254
更新日期:2015-02-01 00:00:00
abstract:AIM:To establish the validity of the Norwegian General Motor Function (NGMF) assessment scale. METHOD:To establish construct and criteria validity, Spearman's rank correlation coefficients were calculated for the NGMF, and age, sex, medical conditions, history of falls and to four functional tests. Content validity wa...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12491
更新日期:2016-04-01 00:00:00
abstract:AIM:To compare the effect of multicomponent and resistance training and detraining on cognition and depressive symptoms in oldest-old community-dwelling people. METHODS:A total of 69 sedentary older adults aged older than 80 years were assessed and randomized into three groups (control, multicomponent and resistance t...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章,随机对照试验
doi:10.1111/ggi.12411
更新日期:2015-09-01 00:00:00
abstract:AIM:There is a high prevalence of combined peripheral and coronary artery disease, with increasing morbidity and decline in cardiac function. The aim of the present study was to find an association between ankle brachial index, a non-invasive measure of peripheral artery disease, and ejection fraction in elderly patien...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.12232
更新日期:2015-04-01 00:00:00
abstract:AIM:Hemoglobin is reported to be positively associated with hypertension. However, the underlying mechanism of this association is unknown. Recently, bone marrow-derived CD34-positive cells have been reported to play an important role in endothelial repair in conjunction with platelets. As the association between hyper...
journal_title:Geriatrics & gerontology international
pub_type: 杂志文章
doi:10.1111/ggi.13068
更新日期:2017-12-01 00:00:00