Synovial cysts of the lumbar spine--pathological considerations and surgical strategy.

Abstract:

:Symptomatic lumbar synovial cysts (LSCs) are a rare cause of degenerative narrowing of the spinal canal, with thecal sac or nerve root compression. True synovial cysts have a thick wall lined by synovial cells, containing granulation tissue, numerous histiocytes, and giant cells. In contrast, pseudo-cysts lack specialized epithelium, have a collagenous capsule filled with myxoid material, and may be classified into ganglion cysts, originating from periarticular fibrous tissues, and ligamentous cysts, arising from the ligamentum flavum or even from the posterior longitudinal ligament. Here we present the surgical series of the Chair of Neurosurgery at the University of Cagliari (Italy) including a total of 17 LSCs. Surgical technique consisted of facet sparing excision of LSC, achieved by simple hemilaminectomy/laminectomy, and diagnosis was always confirmed by histological specimen examination, which detected the typical synovial epithelium, the intracystic presence of hemosiderin, histiocytes, and calcifications. Further immunohistochemical investigation revealed positive staining for cytokeratin: CK5, CK6, and AE1/AE3. Clinically, our cohort experienced rapid and complete resolution of symptoms, without perioperative complications, or recurrence of cysts or vertebral instability at a median follow up of 28 months, when the MacNab score was generally excellent. A review of the literature, retrieving articles published from 1973, collected a total of 101 articles concerning all the cases of LSC scientifically described to date. Both clinical and histological findings described in our study support the theory of degenerative microtraumatic pathogenesis of synovial cysts.

authors

Ganau M,Ennas F,Bellisano G,Ganau L,Ambu R,Faa G,Maleci A

doi

10.2176/nmc.53.95

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

95-102

issue

2

eissn

0470-8105

issn

1349-8029

pii

DN/JST.JSTAGE/nmc/53.95

journal_volume

53

pub_type

杂志文章
  • Transduction efficiency of adenoviral vectors into human glioma cells increased by association with cationic liposomes.

    abstract::Replication-deficient adenoviral vectors are promising agents for human gene therapy of the greater transduction efficiency than other vectors. However, there are distinct disadvantages, including high immunogenicity, which limits the administration to human organs, particularly the brain. Injection of adenoviral vect...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.40.256

    authors: Ryuke Y,Mizuno M,Natsume A,Yoshida J

    更新日期:2000-05-01 00:00:00

  • Survival probability, delayed mortality, and relationship between short-term outcome and long-term survival after aneurysmal subarachnoid hemorrhage.

    abstract::The long-term survival probability, causes of delayed mortality, and relationship between short-term outcome and long-term survival after aneurysmal subarachnoid hemorrhage were retrospectively studied in 106 patients followed up for longer than 5 years. The Kaplan-Meier cumulative survival probabilities at 1 month, 6...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.37.18

    authors: Mori T,Mori K,Kurisaka M,Morimoto M

    更新日期:1997-01-01 00:00:00

  • Unusual location of anterior communicating artery aneurysm located on the planum sphenoidale due to long A1 segments.

    abstract::A 51-year-old woman presented with a rare variation in the location of the anterior communicating artery (AComA) complex associated with aneurysm manifesting as sudden onset of headache. Computed tomography (CT) revealed widespread subarachnoid hemorrhage with intracerebral hematoma and intraventricular hemorrhage. Th...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.48.254

    authors: Kawashima M,Endo M,Kitahara T,Soma K,Fujii K

    更新日期:2008-06-01 00:00:00

  • Remote cerebellar hemorrhage (zebra sign) in vascular neurosurgery: pathophysiological insights.

    abstract::Hemorrhage in regions remote from the site of initial intracranial operations is rare, but may be fatal. Postoperative cerebellar hemorrhage as a complication of supratentorial surgery, with a radiological appearance known as zebra sign, is an increasingly recognized clinical entity and is associated mainly with vascu...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.49.229

    authors: Figueiredo EG,de Amorim RL,Teixeira MJ

    更新日期:2009-06-01 00:00:00

  • Preoperative evaluation of the petrosal vein with contrast-enhanced PRESTO imaging in petroclival meningiomas to establish surgical strategy.

    abstract::The present detailed radiological study investigated the relationship between petroclival meningiomas and petrosal veins with contrast-enhanced (CE) principles of echo-shifting with a train of observations (PRESTO) imaging to assess the potential contribution of the findings to the surgical strategy. Fourteen patients...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.53.490

    authors: Morisako H,Goto T,Chokyu I,Ishibashi K,Ohata K

    更新日期:2013-01-01 00:00:00

  • Superficial siderosis of the central nervous system caused by hemorrhagic intraventricular craniopharyngioma: case report and literature review.

    abstract::Superficial siderosis is a rare condition caused by hemosiderin deposits in the central nervous system (CNS) due to prolonged or recurrent low-grade bleeding into the cerebrospinal fluid (CSF). CNS tumor could be one of the sources of bleeding, both pre- and postoperatively. We report an extremely rare case of superfi...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章,评审

    doi:10.2176/nmc.cr.2012-0362

    authors: Tosaka M,Sato K,Amanuma M,Higuchi T,Arai M,Aishima K,Shimizu T,Horiguchi K,Sugawara K,Yoshimoto Y

    更新日期:2015-01-01 00:00:00

  • [The usefulness of lumbar epidural pressure as an index of intracranial pressure].

    abstract::The reliability of lumbar intraspinal epidural pressure (ISEDP) as an index of intracranial pressure was investigated in seven patients with high intracranial pressure following neurosurgery. ISEDP and intracranial epidural pressure (ICEDP) were measured simultaneously, the latter by the conventional method. ISEDP was...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.29.484

    authors: Fujioka S,Kaku M,Hamada J,Yokota A,Ushio Y

    更新日期:1989-06-01 00:00:00

  • Traumatic carotid-cavernous fistula identified by three-dimensional digital subtraction angiography--technical note.

    abstract::Conventional digital subtraction angiography (DSA) identified a right carotid-cavernous fistula (CCF). Three-dimensional DSA (3D-DSA) was used to evaluate the CCF before treatment. The 3D-DSA images showed the anatomical relationship of the parent artery and the veins, which was difficult to understand on conventional...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.43.369

    authors: Ishida F,Kojima T,Kawaguchi K,Hoshino T,Murao K,Taki W

    更新日期:2003-07-01 00:00:00

  • Multiple isolated sinus dural arteriovenous fistulas associated with antithrombin III deficiency--case report--.

    abstract::A 55-year-old man presented with a rare case of multiple isolated sinus dural arteriovenous fistulas (AVFs) associated with antithrombin (AT) III deficiency manifesting as sudden onset of headache and gait disturbance. Increased arterial shunting flow had caused intraventricular hemorrhage after incomplete repeated tr...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.48.455

    authors: Saito A,Takahashi N,Furuno Y,Kamiyama H,Nishimura S,Midorikawa H,Nishijima M

    更新日期:2008-10-01 00:00:00

  • Burr-hole Irrigation with Closed-system Drainage for the Treatment of Chronic Subdural Hematoma: A Meta-analysis.

    abstract::There is controversy among neurosurgeons regarding whether irrigation or drainage is necessary for achieving a lower revision rate for the treatment of chronic subdural hematoma (CSDH) using burr-hole craniostomy (BHC). Therefore, we performed a meta-analysis of all available published reports. Multiple electronic hea...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章,meta分析,评审

    doi:10.2176/nmc.ra.2015-0013

    authors: Xu C,Chen S,Yuan L,Jing Y

    更新日期:2016-01-01 00:00:00

  • Adverse effects of intravenous acetazolamide administration for evaluation of cerebrovascular reactivity using brain perfusion single-photon emission computed tomography in patients with major cerebral artery steno-occlusive diseases.

    abstract::Adverse effects of intravenous acetazolamide administration for evaluation of cerebrovascular reactivity using brain perfusion single-photon emission computed tomography (SPECT) were prospectively investigated in 100 patients with major cerebral artery, atherosclerotic, and steno-occlusive diseases. All patients under...

    journal_title:Neurologia medico-chirurgica

    pub_type: 临床试验,杂志文章

    doi:10.2176/nmc.51.479

    authors: Saito H,Ogasawara K,Suzuki T,Kuroda H,Kobayashi M,Yoshida K,Kubo Y,Ogawa A

    更新日期:2011-01-01 00:00:00

  • Symptomatic hemorrhage associated with recurrent pilocytic astrocytoma with granulation tissue--case report.

    abstract::A 51-year-old woman had been followed up for 10 years for recurrence of pilocytic astrocytoma 5 years after the initial treatment consisting of subtotal resection, chemotherapy, and radiation therapy. The patient presented with sudden onset of headache and vomiting. Computed tomography and T(2)*-weighted magnetic reso...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.47.222

    authors: Shingu T,Akiyama Y,Daisu M,Maruyama N,Matsumoto Y,Miyazaki T,Nagai H,Yamamoto Y,Yamasaki T,Yoshida M,Maruyama R,Moritake K

    更新日期:2007-05-01 00:00:00

  • Time course of expression of three nitric oxide synthase isoforms after transient middle cerebral artery occlusion in rats.

    abstract::The involvement of nitric oxide synthase (NOS) in ischemia was evaluated by detecting the expression of neuronal NOS (nNOS), endothelial NOS (eNOS), and inducible NOS (iNOS) by the immunohistochemical method in the rat model of middle cerebral artery (MCA) occlusion. Transient MCA occlusion (2 hours) was induced in 32...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.41.63

    authors: Niwa M,Inao S,Takayasu M,Kawai T,Kajita Y,Nihashi T,Kabeya R,Sugimoto T,Yoshida J

    更新日期:2001-02-01 00:00:00

  • Hyperperfusion syndrome following carotid endarterectomy: evaluation using diffusion-weighted magnetic resonance imaging--case report.

    abstract::A 65-year-old female developed hyperperfusion syndrome following carotid endarterectomy for severe stenosis of the left internal carotid artery. Transcranial Doppler monitoring showed a sharp increase in flow velocity in the middle cerebral artery (MCA). Diffusion-weighted magnetic resonance (MR) imaging demonstrated ...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.38.557

    authors: Shinno K,Ueda S,Uno M,Nishitani K,Nagahiro S,Harada M

    更新日期:1998-09-01 00:00:00

  • Bromocriptine-induced morphological changes in cultured growth hormone-producing pituitary adenoma cells.

    abstract::Tumor tissues obtained from two patients with growth hormone-producing pituitary adenomas were cultured and treated with bromocriptine, then examined for morphological changes. Untreated tumor cells (controls) were morphologically well preserved and in terms of growth hormone secretion. Tumor cells exposed to bromocri...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.29.6

    authors: Inoue A,Saito S,Kitamura H,Nakai O

    更新日期:1989-01-01 00:00:00

  • Radiation-induced bilateral cystic frontal lobe necroses demonstrating a fluid-blood level--case report.

    abstract::A 41-year-old male developed radiation-induced bilateral cystic frontal lobe necroses after irradiation for an olfactory neuroblastoma. Computed tomography (CT) and magnetic resonance (MR) imaging revealed the lesions, one containing a fluid-blood level on CT scans and niveau formation on MR images. It was proved to b...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.32.104

    authors: Mineura K,Sasajima T,Kowada M,Ogawa T

    更新日期:1992-02-01 00:00:00

  • Diagnosis of Intracranial Artery Dissection.

    abstract::Cerebral arterial dissection is defined as a hematoma in the wall of a cervical or an intracranial artery. Cerebral arterial dissection causes arterial stenosis, occlusion, and aneurysm, resulting in acute infarction and hemorrhage. Image analysis by such methods as conventional angiography, computed tomography, magne...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章,评审

    doi:10.2176/nmc.ra.2015-0294

    authors: Kanoto M,Hosoya T

    更新日期:2016-09-15 00:00:00

  • Expression of transforming growth factor-beta complex in arteriovenous malformations.

    abstract::The factors responsible for the development of cerebral arteriovenous malformations (AVMs) are not well known. Patients with hereditary hemorrhagic telangiectasia (HHT) have cutaneous vascular dysplasia and a high propensity to develop systemic and cerebral AVMs. Transforming growth factor-beta (TGF-beta) complex has ...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.38.suppl_161

    authors: Malik G,Abdulrauf S,Yang XY,Gutierrez JA,Rempel SA

    更新日期:1998-01-01 00:00:00

  • Delayed parenchymal hemorrhage following successful embolization of brainstem arteriovenous malformation. Case report.

    abstract::A 64-year-old man presented with subarachnoid hemorrhage from a small brainstem arteriovenous malformation (AVM). Cerebral angiography showed a small AVM in the lateral midbrain, which was fed by a basilar perforating artery, and drained into the right transverse pontine vein and superior petrous vein. Endovascular em...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.50.661

    authors: Morihiro Y,Harada K,Kato S,Ishihara H,Shirao S,Nakayama H,Akimura T,Suzuki M

    更新日期:2010-01-01 00:00:00

  • Characterization of immobilized anti-CD3 antibody-activated T lymphocytes for use in adoptive immunotherapy of patients with brain tumors.

    abstract::Large numbers of T lymphocytes were successfully cultured for use in adoptive immunotherapy using immobilized anti-CD3 antibody. This method allows more than 1.5 x 10(10) T lymphocytes to be cultured within 2 weeks from only 20 ml of blood. Proliferated T lymphocytes were less cytotoxic than lymphokine-activated kille...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.32.255

    authors: Yamazaki T,Sekine T

    更新日期:1992-05-01 00:00:00

  • Pituitary abscess showing high uptake of thallium-201 on single photon emission computed tomography--case report.

    abstract::A 32-year-old female presented with a rare case of pituitary abscess manifesting as homonymous hemianopsia. Serum prolactin level was slightly high (40.8 ng/ml). Magnetic resonance (MR) imaging showed the content of the lesion as homogeneously isointense on the T1-weighted images and hyperintense on the T2-weighted im...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.43.100

    authors: Shimamura N,Ogane K,Takahashi T,Tabata H,Ohkuma H,Suzuki S

    更新日期:2003-02-01 00:00:00

  • Giant aneurysm of the azygos anterior cerebral artery--case report.

    abstract::A 77-year-old female presented with a giant aneurysm of the azygos anterior cerebral artery (ACA) manifesting as acute onset of akinetic mutism caused by enlargement of the aneurysm resulting from rapid thrombus formation within the aneurysmal sac. Thrombus removal to obtain decompression of the aneurysmal bulk and te...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.40.472

    authors: Kanemoto Y,Tanaka Y,Nonaka M,Hironaka Y

    更新日期:2000-09-01 00:00:00

  • Morphological effects of tumor necrosis factor-alpha on the blood vessels in rat experimental brain tumors.

    abstract::The morphological changes in the vascular endothelium caused by the administration of tumor necrosis factor-alpha (TNF-alpha) were studied in an experimental model of rat brain tumors. Wistar rats bearing implanted C6 glioma received human natural-type TNF-alpha (1.7 x 10(5) U/m2) through the carotid artery and were s...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.36.423

    authors: Isaka T,Yoshimine T,Maruno M,Hayakawa T

    更新日期:1996-07-01 00:00:00

  • Epidermoid tumor within Meckel's cave--case report.

    abstract::A rare case of an epidermoid tumor lying within Meckel's cave is reported. A 27-year-old housewife presented with complaints of right facial hypesthesia for two and a half years. On examination she had partial loss of touch sensation in the right trigeminal nerve distribution. Magnetic resonance imaging revealed a tum...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.40.74

    authors: Nadkarni T,Dindorkar K,Muzumdar D,Goel A

    更新日期:2000-01-01 00:00:00

  • [Spinal epidural cavernous hemangioma. Case report].

    abstract::Spinal epidural cavernous hemangiomas are very rare; only 18 cases have been reported in the literature. The authors describe the case of a 38-year-old male whose first symptom was numbness of the foot, which, after 2 years, spread to the abdomen. On admission, he had no weakness but exhibited hyper-reflex of the lowe...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章,评审

    doi:10.2176/nmc.29.538

    authors: Kurose K,Kishi H,Sadatoh T

    更新日期:1989-06-01 00:00:00

  • High titer retroviral gene transduction to neural progenitor cells for establishment of donor cells for neural transplantation to parkinsonian model rats.

    abstract::Neural progenitor cells (NPCs) are expected to be useful donor sources for cell transplantation therapy in Parkinson's disease. However, control of the differentiational lineage, especially into dopaminergic neurons, is still difficult. Thus, genetic modification of NPCs to produce l-dopa is potentially useful. The pr...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.44.344

    authors: Kodama Y,Hida H,Jung CG,Baba H,Isono M,Kobayashi H,Nishino H

    更新日期:2004-07-01 00:00:00

  • Spontaneous resolution of delayed onset large subclavian artery pseudoaneurysm.

    abstract::A 70-year-old woman with a history of end-stage renal disease secondary to anti-neutrophil cytoplasmic autoantibody-associated vasculitis had been receiving hemodialysis for 5 years. The patient underwent attempted right internal jugular vein cannulation for temporary hemodialysis catheter placement. Pulsating mass de...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.49.517

    authors: Ohta T,Maekawa H,Kasuno K,Tsukamoto T,Muso E,Ishikawa M

    更新日期:2009-11-01 00:00:00

  • Dynamic magnetic resonance appearance of the vertebral dissecting aneurysm--case report.

    abstract::A dissecting aneurysm of the vertebral artery occurred in a 38-year-old male presenting with ischemic attacks. Vertebral angiography revealed irregular narrowing and dilatation of the right vertebral artery, and retention of the contrast medium. Routine T1-weighted magnetic resonance (MR) imaging demonstrated signal v...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.32.698

    authors: Hamada J,Sato K,Nagahiro S,Ushio Y

    更新日期:1992-08-01 00:00:00

  • Analysis of retained ventricular shunt catheters.

    abstract::To identify the causes of ventricular shunt catheter retention, 42 shunt removals in 28 patients in our neurosurgical clinic from 1982 to 1991 were analyzed. The mean patient age was 13.8 years (2 mos-78 yrs), and mean shunt duration was 20.1 months (0.5-94 mos). There were nine retained ventricular catheters, includi...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.32.824

    authors: Koga H,Mukawa J,Nakata M,Sakuta O,Higa Y

    更新日期:1992-10-01 00:00:00

  • Acute subdural hematoma in patients who underwent aneurysm clipping--four case reports.

    abstract::Four patients presented with intracranial hemorrhage mainly consisting of acute subdural hematoma (ASDH), who had all undergone aneurysm clipping 2-20 years earlier. Whether the clips had slipped or new trauma had caused the bleeding was difficult to determine, since the initial computed tomography showed that the sub...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.41.393

    authors: Imaizumi S,Owada K,Onuma T,Kameyama M

    更新日期:2001-08-01 00:00:00