Application of random match probability calculations to mixed STR profiles.

Abstract:

:Mixed DNA profiles are being encountered more frequently as laboratories analyze increasing amounts of touch evidence. If it is determined that an individual could be a possible contributor to the mixture, it is necessary to perform a statistical analysis to allow an assignment of weight to the evidence. Currently, the combined probability of inclusion (CPI) and the likelihood ratio (LR) are the most commonly used methods to perform the statistical analysis. A third method, random match probability (RMP), is available. This article compares the advantages and disadvantages of the CPI and LR methods to the RMP method. We demonstrate that although the LR method is still considered the most powerful of the binary methods, the RMP and LR methods make similar use of the observed data such as peak height, assumed number of contributors, and known contributors where the CPI calculation tends to waste information and be less informative.

journal_name

J Forensic Sci

authors

Bille T,Bright JA,Buckleton J

doi

10.1111/1556-4029.12067

subject

Has Abstract

pub_date

2013-03-01 00:00:00

pages

474-85

issue

2

eissn

0022-1198

issn

1556-4029

journal_volume

58

pub_type

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