Characterization of the Bat proteins in the oxidative stress response of Leptospira biflexa.

abstract：BACKGROUND:Several conventional methods, including fungal culture and periodic acid-Schiff (PAS) reagent staining, have been used to diagnose oral candidiasis. The aim of this study was to evaluate the efficacy of a novel method, fungal fluorescent staining, in relation to conventional protocols in the diagnosis of ora...

journal_title：BMC microbiology

authors： Yao Y,Shi L,Zhang C,Sun H,Wu L

更新日期：2019-05-14 00:00:00

abstract：BACKGROUND:Pseudomonas syringae is pathogenic to a large number of plant species. For host colonization and disease progression, strains of this bacterium utilize an array of type III-secreted effectors and other virulence factors, including small secreted molecules such as syringolin A, a peptide derivative that inhib...

journal_title：BMC microbiology

authors： Dudnik A,Dudler R

更新日期：2014-12-04 00:00:00

abstract：BACKGROUND:It has recently been reported that intermittent fasting shapes the gut microbiota to benefit health, but this effect may be influenced to the exact fasting protocols. The purpose of this study was to assess the effects of different daily fasting hours on shaping the gut microbiota in mice. Healthy C57BL/6 J ...

journal_title：BMC microbiology

authors： Li L,Su Y,Li F,Wang Y,Ma Z,Li Z,Su J

更新日期：2020-03-24 00:00:00

abstract：BACKGROUND:Many plants have been used in traditional medicine for their antibacterial, antifungal, antiprotozoal, antiviral, antidiarrhoeal, analgesic, antimalarial, antioxidant, anti-inflammatory and anticancer activities. In order to find novel antimicrobial and antiviral agents, the aim of the present study was the ...

journal_title：BMC microbiology

authors： Di Petrillo A,Fais A,Pintus F,Santos-Buelga C,González-Paramás AM,Piras V,Orrù G,Mameli A,Tramontano E,Frau A

更新日期：2017-07-14 00:00:00

abstract：BACKGROUND:Legionella testing conducted at environmental laboratories plays an essential role in assessing the risk of disease transmission associated with water systems. However, drawbacks of culture-based methodology used for Legionella enumeration can have great impact on the results and interpretation which togethe...

journal_title：BMC microbiology

authors： Díaz-Flores Á,Montero JC,Castro FJ,Alejandres EM,Bayón C,Solís I,Fernández-Lafuente R,Rodríguez G

更新日期：2015-04-29 00:00:00

abstract：BACKGROUND:Macrolides and lincosamides are two leading types of antibiotics commonly used in therapies. The study examines the differences in resistance to these antibiotics and their molecular bases in S. epidermidis as well as in rarely isolated species of coagulase-negative staphylococci such as S. hominis, S. haemo...

journal_title：BMC microbiology

authors： Szemraj M,Czekaj T,Kalisz J,Szewczyk EM

更新日期：2019-06-10 00:00:00

abstract：BACKGROUND:Recent scientific developments have shed more light on the importance of the host-microbe interaction, particularly in the gut. However, the mechanistic study of the host-microbe interplay is complicated by the intrinsic limitations in reaching the different areas of the gastrointestinal tract (GIT) in vivo....

journal_title：BMC microbiology

authors： Marzorati M,Vanhoecke B,De Ryck T,Sadaghian Sadabad M,Pinheiro I,Possemiers S,Van den Abbeele P,Derycke L,Bracke M,Pieters J,Hennebel T,Harmsen HJ,Verstraete W,Van de Wiele T

更新日期：2014-05-22 00:00:00

abstract：BACKGROUND:Epitope tagging is a powerful strategy to study the function of proteins. Although tools for C-terminal protein tagging in the ciliated protozoan Tetrahymena thermophila have been developed, N-terminal protein tagging in this organism is still technically demanding. RESULTS:In this study, we have establishe...

journal_title：BMC microbiology

authors： Busch CJ,Vogt A,Mochizuki K

更新日期：2010-07-13 00:00:00

abstract：BACKGROUND:Affecting the core functional microbiome, peculiar high level taxonomic unbalances of the human intestinal microbiota have been recently associated with specific diseases, such as obesity, inflammatory bowel diseases, and intestinal inflammation. RESULTS:In order to specifically monitor microbiota unbalance...

journal_title：BMC microbiology

authors： Candela M,Consolandi C,Severgnini M,Biagi E,Castiglioni B,Vitali B,De Bellis G,Brigidi P

更新日期：2010-04-19 00:00:00

abstract：BACKGROUND:Pectobacterium carotovorum subsp. carotovorum is a phytopathogenic enterobacterium responsible for soft rot, a disease characterized by extensive maceration of the affected plant tissue. This species also produces two or more antibacterial substances called bacteriocins, which enhance its competitiveness aga...

journal_title：BMC microbiology

authors： Chan YC,Wu HP,Chuang DY

更新日期：2009-08-27 00:00:00

abstract：BACKGROUND:Lactic acid bacteria (LAB) are major inhabitants and part of the normal microflora of the gastrointestinal tract (GIT) of humans and animals. Despite substantial evidence supporting the beneficial properties of LAB, only a few studies have addressed the migration and colonization of probiotic bacteria in the...

journal_title：BMC microbiology

authors： Van Zyl WF,Deane SM,Dicks LMT

更新日期：2018-10-30 00:00:00

abstract：BACKGROUND:The Gifsy-I phage integrates into the Salmonella Typhimurium chromosome via an integrase mediated, site-specific recombination mechanism. Excision of the Gifsy-I phage requires three proteins, the Gifsy-I integrase (Int), the Gifsy-I excisionase (Xis) protein, and host encoded Integration Host Factor (IHF). ...

journal_title：BMC microbiology

authors： Flanigan A,Gardner J

更新日期：2008-11-17 00:00:00

abstract：BACKGROUND:Human granulocytic anaplasmosis (HGA) is a tick-borne disease caused by the etiologic agent Anaplasma phagocytophilum. HGA was designated a nationally notifiable disease in the United States in 1998. Currently there are no vaccines available against HGA. Conserved membrane proteins that are subdominant in An...

journal_title：BMC microbiology

authors： Crosby FL,Lundgren AM,Hoffman C,Pascual DW,Barbet AF

更新日期：2018-12-18 00:00:00

abstract：BACKGROUND:Bacterial lipoproteins often play important roles in pathogenesis and can stimulate protective immune responses. Such lipoproteins are viable vaccine candidates. Haemophilus ducreyi, which causes the sexually transmitted disease chancroid, expresses a number of lipoproteins during human infection. One such l...

journal_title：BMC microbiology

authors： Janowicz DM,Zwickl BW,Fortney KR,Katz BP,Bauer ME

更新日期：2014-06-24 00:00:00

abstract：BACKGROUND:Recent studies suggest that the reported protective effects of statins (HMG-CoA reductase inhibitors) against community-acquired pneumonia (CAP) and sepsis in humans may be due to confounders and a healthy user-effect. To directly test whether statins are protective against Streptococcus pneumoniae, the lead...

journal_title：BMC microbiology

authors： Boyd AR,Hinojosa CA,Rodriguez PJ,Orihuela CJ

更新日期：2012-05-15 00:00:00

abstract：BACKGROUND:The increase in resistance to antibiotics among disease-causing bacteria necessitates the development of alternative antimicrobial approaches such as the use of light-activated antimicrobial agents (LAAAs). Light of an appropriate wavelength activates the LAAA to produce cytotoxic species which can then caus...

journal_title：BMC microbiology

authors： Omar GS,Wilson M,Nair SP

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Bacterial and cellular genotyping is becoming increasingly important in the diagnosis of infectious diseases. However, difficulties in obtaining sufficient amount of bacterial and cellular DNA extracted from the same human biopsy specimens is often a limiting factor. In this study, total DNA (host and bacter...

journal_title：BMC microbiology

authors： Ryberg A,Borch K,Sun YQ,Monstein HJ

更新日期：2008-10-08 00:00:00

abstract：BACKGROUND:The naked mole-rat (NMR, Heterocephalus glaber) is being bred as a novel laboratory animal due to its unique biological characteristics, including longevity, cancer resistance, hypoxia tolerance, and pain insensitivity. It is expected that differences exist between the microbiota of wild NMRs and that of NMR...

journal_title：BMC microbiology

authors： Cong W,Xing J,Feng Y,Wang J,Fu R,Yue B,He Z,Lin L,Yang W,Cheng J,Sun W,Cui S

更新日期：2018-08-22 00:00:00

abstract：BACKGROUND:Glycopeptidolipids (GPLs) are among the major free glycolipid components of the outer membrane of several saprophytic and clinically-relevant Mycobacterium species. The architecture of GPLs is based on a constant tripeptide-amino alcohol core of nonribosomal peptide synthetase origin that is N-acylated with ...

journal_title：BMC microbiology

authors： Tatham E,Sundaram Chavadi S,Mohandas P,Edupuganti UR,Angala SK,Chatterjee D,Quadri LE

更新日期：2012-06-22 00:00:00

abstract：BACKGROUND:Iron is an essential nutrient but can be toxic at high intracellular concentrations and organisms have evolved tightly regulated mechanisms for iron uptake and homeostasis. Information on iron management mechanisms is available for organisms living at circumneutral pH. However, very little is known about how...

journal_title：BMC microbiology

authors： Osorio H,Martínez V,Nieto PA,Holmes DS,Quatrini R

更新日期：2008-11-24 00:00:00

abstract：BACKGROUND:Fluconazole (FLC), a triazole antifungal drug, is widely used for the maintenance therapy of cryptococcal meningoencephalitis, the most common opportunistic infection in AIDS patients. In this study, we examined changes in the gene expression profile of the C. neoformans reference strain H99 (serotype A) fol...

journal_title：BMC microbiology

authors： Florio AR,Ferrari S,De Carolis E,Torelli R,Fadda G,Sanguinetti M,Sanglard D,Posteraro B

更新日期：2011-05-11 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV), because of its error-prone viral polymerase, has a high mutation rate leading to widespread substitutions, deletions, and insertions in the HBV genome. Deletions may significantly change viral biological features complicating the progression of liver diseases. However, the clinical c...

journal_title：BMC microbiology

authors： Zhang D,Dong P,Zhang K,Deng L,Bach C,Chen W,Li F,Protzer U,Ding H,Zeng C

更新日期：2012-12-28 00:00:00

abstract：BACKGROUND:Probiotics are increasingly applied to prevent and treat a range of infectious, immune related and gastrointestinal diseases. Despite this, the mechanisms behind the putative effects of probiotics are poorly understood. One of the suggested modes of probiotic action is modulation of the endogenous gut microb...

journal_title：BMC microbiology

authors： Laursen MF,Laursen RP,Larnkjær A,Michaelsen KF,Bahl MI,Licht TR

更新日期：2017-08-17 00:00:00

abstract：BACKGROUND:Streptococcus agalactiae (GBS) is a common pathogen to infect newborn, woman, the elderly, and immuno-compromised human and fish. 37 fish isolates and 554 human isolates of the GBS in 2007-2012 were investigated in serotypes, antibiotic susceptibility, genetic difference and pathogenicity to tilapia. RESULT...

journal_title：BMC microbiology

authors： Chu C,Huang PY,Chen HM,Wang YH,Tsai IA,Lu CC,Chen CC

更新日期：2016-08-02 00:00:00

abstract：BACKGROUND:The development of vaccines and evaluation of novel treatment strategies for invasive group A streptococcal (iGAS) disease requires suitable models of human infection that can be monitored longitudinally and are preferably non-invasive. Bio-photonic imaging provides an opportunity to reduce use of animals in...

journal_title：BMC microbiology

authors： Lamb LE,Zhi X,Alam F,Pyzio M,Scudamore CL,Wiles S,Sriskandan S

更新日期：2018-06-19 00:00:00

abstract：BACKGROUND:Zinc is an essential element for all living cells. Recent studies have shown that the ZnuABC zinc uptake system significantly contributes to the ability of several pathogens to multiply in the infected host and cause disease, suggesting that zinc is scarcely available within different tissues of the host. To...

journal_title：BMC microbiology

authors： Gabbianelli R,Scotti R,Ammendola S,Petrarca P,Nicolini L,Battistoni A

更新日期：2011-02-21 00:00:00

abstract：BACKGROUND:Tsetse flies (Diptera: Glossinidae) are solely responsible for the transmission of African trypanosomes, causative agents of sleeping sickness in humans and nagana in livestock. Due to the lack of efficient vaccines and the emergence of drug resistance, vector control approaches such as the sterile insect te...

journal_title：BMC microbiology

authors： Augustinos AA,Meki IK,Demirbas-Uzel G,Ouédraogo GMS,Saridaki A,Tsiamis G,Parker AG,Abd-Alla AMM,Bourtzis K

更新日期：2018-11-23 00:00:00

abstract：BACKGROUND:Wogonin, a natural flavonoid-like chemical compound, exhibits anti-inflammatory, antitumor, antiviral, neuroprotective, and anxiolytic effects by modulating a variety of cellular signaling pathways including PI3K-Akt, p53, nuclear factor κB (NF-κB), mitogen-activated protein kinase (MAPK) pathways. In this s...

journal_title：BMC microbiology

authors： Chu Y,Lv X,Zhang L,Fu X,Song S,Su A,Chen D,Xu L,Wang Y,Wu Z,Yun Z

更新日期：2020-07-28 00:00:00

abstract：BACKGROUND:Photorhabdus are Gram-negative nematode-symbiotic and insect-pathogenic bacteria. The species Photorhabdus asymbiotica is able to infect humans as well as insects. We investigated the secreted proteome of a clinical isolate of P. asymbiotica at different temperatures in order to identify proteins relevant to...

journal_title：BMC microbiology

authors： Jones RT,Sanchez-Contreras M,Vlisidou I,Amos MR,Yang G,Muñoz-Berbel X,Upadhyay A,Potter UJ,Joyce SA,Ciche TA,Jenkins AT,Bagby S,Ffrench-Constant RH,Waterfield NR

更新日期：2010-05-12 00:00:00

abstract：BACKGROUND:A disrupted cell cycle progression of hepatocytes was reported in chronic hepatitis C virus (HCV) infection, which can contribute significantly in the associated pathogenesis. The present study aimed to further elaborate these disruptions by evaluating the expression of key cell cycle and apoptotic proteins ...

journal_title：BMC microbiology

authors： Sarfraz S,Hamid S,Siddiqui A,Hussain S,Pervez S,Alexander G

更新日期：2008-08-05 00:00:00