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Dual targeting and retrograde translocation: regulators of plant nuclear gene expression can be sequestered by plastids.

Abstract：

:Changes in the developmental or metabolic state of plastids can trigger profound changes in the transcript profiles of nuclear genes. Many nuclear transcription factors were shown to be controlled by signals generated in the organelles. In addition to the many different compounds for which an involvement in retrograde signaling is discussed, accumulating evidence suggests a role for proteins in plastid-to-nucleus communication. These proteins might be sequestered in the plastids before they act as transcriptional regulators in the nucleus. Indeed, several proteins exhibiting a dual localization in the plastids and the nucleus are promising candidates for such a direct signal transduction involving regulatory protein storage in the plastids. Among such proteins, the nuclear transcription factor WHIRLY1 stands out as being the only protein for which an export from plastids and translocation to the nucleus has been experimentally demonstrated. Other proteins, however, strongly support the notion that this pathway might be more common than currently believed.

journal_name

Int J Mol Sci

journal_title

International journal of molecular sciences

authors

Krause K,Oetke S,Krupinska K

doi

10.3390/ijms130911085

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

11085-101

issue

9

issn

1422-0067

pii

ijms-13-11085

journal_volume

13

pub_type

杂志文章,评审

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