Abstract:
OBJECTIVE:The purpose of this study was to evaluate the different patterns of bone loss between the lumbar spine and the femur after ovariectomy in rats. METHODS:Twenty-four female Sprague-Dawley rats underwent a sham operation (the sham group) or bilateral ovariectomy (the ovariectomized group). Four and eight weeks after operation, six rats from each of the two groups were euthanized. Serum biochemical markers of bone turnover including osteocalcin and alkaline phosphatase (ALP), which are sensitive biochemical markers of bone formation, and the telopeptide fragment of type I collagen C-terminus (CTX), which is a sensitive biochemical marker of bone resorption, were analyzed. Bone histomorphometric parameters of the 4th lumbar vertebrae and femur were determined by micro-computed tomography. RESULTS:Ovariectomized rats were found to have higher osteocalcin, ALP and CTX levels than sham controls. Additionally, 8 weeks after ovariectomy in the OVX group, serum levels of osteocalcin, ALP and CTX were significantly higher than those of 4 weeks after ovariectomy. Bone loss after ovariectomy was more extensive in the 4th lumbar spine compared to the femur. Bone loss in the 4th lumbar spine was mainly caused by trabecular thinning, but in the femur, it was mainly caused by trabecular elimination. CONCLUSION:The present study demonstrates different patterns of bone loss between the 4th lumbar spine and the femur in ovariectomized rats. Therefore, when considering animal models of osteoporosis, it is important that bone sites should be taken into account.
journal_name
J Korean Neurosurg Socjournal_title
Journal of Korean Neurosurgical Societyauthors
Shin YH,Cho DC,Yu SH,Kim KT,Cho HJ,Sung JKdoi
10.3340/jkns.2012.52.1.1subject
Has Abstractpub_date
2012-07-01 00:00:00pages
1-6issue
1eissn
2005-3711issn
1598-7876journal_volume
52pub_type
杂志文章abstract:OBJECTIVE:The aim of this study is to investigate good prognostic factors for an acute occlusion of a major cerebral artery using mechanical thrombectomy. METHODS:Between January 2013 to December 2014, 37 consecutive patients with acute occlusion of a major cerebral artery treated by mechanical thrombectomy with stent...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2015.58.3.192
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:This study characterized the neurons in the lumbosacral cord that express phospho ERK (pERK) after distension or irritation of the bladder, and their relation to the vanilloid receptor 1 (VR1) positive primary afferents. METHODS:Mechanical distension and chemical irritation of the bladder were induced by int...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2007.42.6.462
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVE:The indications and optimal surgical treatments for intracranial cysts are controversial. In the present study, we describe long-term clinical and neuroimaging results of surgically treated intracranial cysts in children. The goal of this study is to contribute to the discussion of the debate. METHODS:This s...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2012.52.4.325
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the relationship between postoperative increase in intervertebral disc space height (IVH) and posterior axial neck in cases of degenerative cervical disease treated with anterior cervical discectomy and fusion (ACDF). METHODS:A total of 155 patients who underwent ACDF with more than 1 year follow...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2014.55.6.343
更新日期:2014-06-01 00:00:00
abstract::Among the spinal disorders, the treatment approach for spinal deformities has been discussed least among department of neurosurgery. But nowadays, more and more neurosurgeons are interested in spinal deformities as well as complex spinal disorders and are doing not a few surgeries for these kinds of disease. Neverthel...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2018.0150
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVE:The clinical and pathological characteristics of 10 cases of cerebral amyloid angiopathy (CAA)-related cerebral lobar hemorrhage (CLH) that was diagnosed at autopsy were investigated to facilitate the diagnosis of this condition. METHODS:The clinical characteristics of 10 cases of CAA-related CLH were retros...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2015.58.1.30
更新日期:2015-07-01 00:00:00
abstract:Objective:To explore the correlation between the polymorphism of histone deacetylase 9 gene (rs1060499865, rs723296, rs957960) and ischemic stroke (IS) in Chinese Han population in Dali region. Methods:This study included 155 IS patients and 128 healthy physical examinees. TaqMan-polymerase chain reaction technology a...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2020.0040
更新日期:2020-11-24 00:00:00
abstract:OBJECTIVE:To investigate the feasibility of C1 lateral mass screw and C2 pedicle screw with polyaxial screw and rod system supplemented with miniplate for interlaminar fusion to treat various atlantoaxial instabilities. METHODS:After posterior atlantoaxial fixation with lateral mass screw in the atlas and pedicle scre...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2012.52.2.120
更新日期:2012-08-01 00:00:00
abstract::Owing to the focal wall defect covered with thin fibrous tissues, an aneurysm arising from the dorsal wall of the internal carotid artery (ICA) is difficult to manage either surgically or endovascularly and is often associated with high morbidity and mortality. Unfortunately, the definitive treatment modality of such ...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2014.56.6.496
更新日期:2014-12-01 00:00:00
abstract::We report a case of infantile fibrosarcoma in an 8-month-old boy manifested as a right-sided lower leg mass. Repeated local recurrence and distant metastasis were noted during the following three-year period. Whole body fluoro-deoxyglucose positron emission tomography scan revealed an asymptomatic metastasis involving...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2013.54.6.528
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:The aim of the study is to determine the efficacy of indocyanine green (ICG) videoangiography for confirmation of vascular anastomosis patency in both extracranial-intracranial and intracranial-intracranial bypasses. METHODS:Intraoperative ICG videoangiography was used as a surgical adjunct for 56 bypasses i...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2011.50.1.23
更新日期:2011-07-01 00:00:00
abstract::Fusiform aneurysms on the basilar artery (BA) trunk are rare. The microsurgical management of these aneurysms is difficult because of their deep location, dense collection of vital cranial nerves, and perforating arteries to the brain stem. Endovascular treatment is relatively easier and safer compared with microsurgi...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2013.53.4.235
更新日期:2013-04-01 00:00:00
abstract::Spinal epidural hematoma is a rare complication associated with pain control procedures such as facet block, acupuncture, epidural injection, etc. Although it is an uncommon cause of acute myelopathy, and it may require surgical evacuation. We report four patients with epidural hematoma developed after pain control pr...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2010.48.3.281
更新日期:2010-09-01 00:00:00
abstract::The intra-arterial administration of nimodipine (IAN) is commonly used for cerebral vasospasm refractory to medical treatments. We report two cases of vasogenic edema after IAN. Our patients with aneurismal subarachnoid hemorrhage presented with vasospasm, which was treated by IAN. Consequently, vasogenic edema develo...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2011.49.2.112
更新日期:2011-02-01 00:00:00
abstract::We report two rare cases of spinal intraosseous schwannoma (SIS) with sustained myelopathy symptoms and provide an updated review regarding SIS in the literature. A 71-year-old man experienced right lumbocrural pain and gait disturbance accompanied with paresthesia and right leg weakness. Imaging examinations revealed...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2015.57.6.478
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVE:Metaplastic meningioma is an extremely rare subtype of World Health Organization (WHO) grade I meningioma. It has distinctive histological subtypes according to its own mesenchymal components. Owing to its scarcity, clinical or radiological features of a metaplastic meningioma are poorly described. METHODS:B...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2020.0151
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:The aneurysm remnants rate was evaluated via three-dimensional digital subtraction angiography (3D-DSA) in the postoperative evaluation of clipped aneurysms. METHODS:Data on surgically clipped aneurysms of anterior circulation obtained via postoperative 3D-DSA from February 2007 to March 2009 were gathered. ...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2010.47.3.185
更新日期:2010-03-01 00:00:00
abstract::Congenital anomalies in arches of the atlas are rare, and are usually discovered incidentally. However, a very rare subgroup of patients with unique radiographic features is predisposed to transient quadriparesis after minor cervical or head trauma. A 46-year-old male presented with a 2-month history of tremor and hyp...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2011.49.3.178
更新日期:2011-03-01 00:00:00
abstract::Isolated cortical vein thrombosis (ICVT) is a rare disease, accounting for less than 1% of strokes. A 46-year-old woman presented with progressive left side weakness. Magnetic resonance (MR) imaging with T2(*)-gradient echo (T2(*)-GE) sequence showed long cord sign at the right frontal cortex. The patient was treated ...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2015.58.5.476
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVE:Mechanical thrombectomy (MT) for acute intracranial internal carotid artery (ICA) occlusion is often complicated by difficult revascularization and non-involved territory embolization possibly related with larger clot-burden. This study aims to evaluate the efficacy of proximal aspiration thrombectomy (PAT) u...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2016.59.4.379
更新日期:2016-07-01 00:00:00
abstract::The authors present a case of isolated dural arteriovenous fistula (DAVF) in the transverse sinus, which developed six years after microvascular decompression caused by hemifacial spasm via suboccipital craniectomy. The lesion was successfully treated by transarterial embolization using Onyx. We reviewed the related r...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2012.52.5.480
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:The objectives of this study was to determine the incidence and outcomes of procedural rupture (PR) during coil embolization of unruptured intracranial aneurysm (UIA) and to explore potential risk factors. METHODS:This retrospective study evaluated 1038 patients treated with coil embolization between January...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2016.59.1.6
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:Meningioma is the second most common primary central nervous system neoplasm. In contrast, chordoid meningioma is rare; due to the paucity of cases, little is known about its clinical features or treatment outcomes. The objectives of this study were to describe the clinical characteristics and outcomes for pa...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2014.56.3.194
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:The objectives of the present study were to characterize the natural course of initially non-operated traumatic acute subdural hematoma (ASDH) and to identify the risk factors of hematoma progression. METHODS:Retrospective analysis was performed using sequential computed tomography (CT) images maintained in ...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2013.54.3.211
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:The diagnosis of insufficiency fractures of the sacrum in an elder population increases annually. Fractures show very different morphology. We aimed to classify sacral insufficiency fractures according to the position of cortical break and possible need for intervention. METHODS:Between January 1, 2008 and D...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2017.0188
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:According to the recent development of minimally invasive spinal surgery, direct lumbar interbody fusion (DLIF) was introduced as an effective option to treat lumbar degenerative diseases. However, comprehensive results of DLIF have not been reported in Korea yet. The object of this study is to summarize radi...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2014.55.5.248
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVE:Posture-induced radial neuropathy, known as Saturday night palsy, occurs because of compression of the radial nerve. The clinical symptoms of radial neuropathy are similar to stroke or a herniated cervical disk, which makes it difficult to diagnose and sometimes leads to inappropriate evaluations. The purpose...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2014.55.3.148
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVE:The potassium disturbance associated with thiopental continuous infusion in neurosurgical patients is well known. However, the effect of propofol continuous infusion on serum potassium levels has not been investigated extensively. METHODS:We reviewed the medical records of 60 consecutive patients who receive...
journal_title:Journal of Korean Neurosurgical Society
pub_type: 杂志文章
doi:10.3340/jkns.2015.57.3.197
更新日期:2015-03-01 00:00:00
abstract::Sacral insufficiency fractures are usually known to develop in elderly patients with osteoporosis without definite trauma history. It is difficult to diagnose the sacral insufficiency fracture at an early stage because lower lumbar diseases, concurrently or not, may also be presented with similar symptoms and signs. W...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2008.44.3.166
更新日期:2008-09-01 00:00:00
abstract::Lymphomatosis cerebri is considered a diffuse form of primary central nervous system lymphoma and very rare. It is not well recognized and may be misdiagnosed with infiltrating tumors, degenerative disorders, ischemic diseases, and infectious diseases developed in the brain. Awareness of the possibility of this rare d...
journal_title:Journal of Korean Neurosurgical Society
pub_type:
doi:10.3340/jkns.2013.54.5.420
更新日期:2013-11-01 00:00:00