Successful treatment of infantile fibrosarcoma spinal metastasis by chemotherapy and stereotactic hypofractionated radiotherapy.

Abstract:

:We report a case of infantile fibrosarcoma in an 8-month-old boy manifested as a right-sided lower leg mass. Repeated local recurrence and distant metastasis were noted during the following three-year period. Whole body fluoro-deoxyglucose positron emission tomography scan revealed an asymptomatic metastasis involving the fourth lumbar vertebrae. The patient received chemotherapy (VAC regimen) with Cyberknife® stereotactic hypofractionated radiotherapy (26 Gy; 4 fractions). This treatment reduced tumor size by 23% without acute radiation toxicity even after 33 months. This case suggests that combining chemotherapy and this form of radiotherapy may be safe and effective against childhood spinal metastasis.

journal_name

J Korean Neurosurg Soc

authors

Lo CH,Cheng SN,Lin KT,Jen YM

doi

10.3340/jkns.2013.54.6.528

subject

Has Abstract

pub_date

2013-12-01 00:00:00

pages

528-31

issue

6

eissn

2005-3711

issn

1598-7876

journal_volume

54

pub_type

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    doi:10.3340/jkns.2015.58.5.476

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    journal_title:Journal of Korean Neurosurgical Society

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    doi:10.3340/jkns.2009.45.2.99

    authors: Park JH,Nam TK,Hwang SN,Park SW

    更新日期:2009-02-01 00:00:00

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    doi:10.3340/jkns.2013.53.4.235

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    doi:10.3340/jkns.2009.46.2.161

    authors: Kim DJ,Choi YS,Song YJ,Kim KU

    更新日期:2009-08-01 00:00:00

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    pub_type:

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    authors: Kim E,Nam SI

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    pub_type:

    doi:10.3340/jkns.2011.49.6.377

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