Abstract：
OBJECTIVE:Meningioma is the second most common primary central nervous system neoplasm. In contrast, chordoid meningioma is rare; due to the paucity of cases, little is known about its clinical features or treatment outcomes. The objectives of this study were to describe the clinical characteristics and outcomes for patients with chordoid meningioma. METHODS:In total, 16 patients, with newly diagnosed chordoid meningioma who underwent surgical excision between 1999 and 2012 were included. We retrospectively evaluated the medical records, radiological findings, and pathological findings. The median follow-up period was 56.5 (range, 3-170) months. The MIB-1 labeling index ranged from 1 to 26.60% (median, 5.04). RESULTS:Simpson grade I, II, and III resections were performed in four, nine, and three patients, respectively. The overall recurrence rate was 37.5%. Overall progression-free survival (PFS) after resection was 94.7 months (95% CI=62.9-126.6). Of the 4 patients with Simpson grade I resection, recurrence occurred in one patient. Among the Simpson grade II and III resection groups, eight patients underwent adjuvant radiation therapy and they showed significantly longer PFS (121 months, 95% CI=82.1-159.9) than the patients who underwent surgery alone (40.5 months, 95% CI=9.6-71.3) by the log-rank test (p<0.05). CONCLUSION:Chordoid meningiomas are difficult to manage and have a high rate of recurrence. Complete resection of the tumor is a key determinant of better outcomes. Adjuvant radiation therapy is recommended, eparticulary when Simpson grade I resection was not achieved.
journal_name
J Korean Neurosurg Socjournal_title
Journal of Korean Neurosurgical Societyauthors
Jee TK,Jo KI,Seol HJ,Kong DS,Lee JI,Shin HJdoi
10.3340/jkns.2014.56.3.194subject
Has Abstractpub_date
2014-09-01 00:00:00pages
194-9issue
3eissn
2005-3711issn
1598-7876journal_volume
56pub_type
杂志文章abstract：:Diffuse intrinsic pontine glioma (DIPG) is a deadly paediatric brain cancer. Transient response to radiation, ineffective chemotherapeutic agents and aggressive biology result in rapid progression of symptoms and a dismal prognosis. Increased availability of tumour tissue has enabled the identification of histone gene...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章,评审
doi：10.3340/jkns.2018.0008
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abstract：:We report a case of infantile fibrosarcoma in an 8-month-old boy manifested as a right-sided lower leg mass. Repeated local recurrence and distant metastasis were noted during the following three-year period. Whole body fluoro-deoxyglucose positron emission tomography scan revealed an asymptomatic metastasis involving...
journal_title：Journal of Korean Neurosurgical Society
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doi：10.3340/jkns.2013.54.6.528
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2018.0150
更新日期：2018-11-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2010.47.6.442
更新日期：2010-06-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2014.56.1.16
更新日期：2014-07-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2020.0040
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journal_title：Journal of Korean Neurosurgical Society
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doi：10.3340/jkns.2013.54.2.136
更新日期：2013-08-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2014.55.5.248
更新日期：2014-05-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
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doi：10.3340/jkns.2015.58.2.137
更新日期：2015-08-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
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doi：10.3340/jkns.2012.52.5.480
更新日期：2012-11-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2010.47.3.185
更新日期：2010-03-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2019.0108
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journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2010.48.4.375
更新日期：2010-10-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2018.0045
更新日期：2018-09-01 00:00:00
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pub_type： 杂志文章
doi：10.3340/jkns.2016.1010.003
更新日期：2017-11-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2007.42.4.300
更新日期：2007-10-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2009.46.3.265
更新日期：2009-09-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
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pub_type：
doi：10.3340/jkns.2010.47.5.385
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doi：10.3340/jkns.2013.54.4.344
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2015.58.3.254
更新日期：2015-09-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2009.45.2.99
更新日期：2009-02-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type：
doi：10.3340/jkns.2013.53.3.183
更新日期：2013-03-01 00:00:00
abstract：OBJECTIVE:Both endovascular coil embolization and microsurgical clipping are now firmly established as treatment options for the management of cerebral aneurysms. Moreover, they are sometimes used as complementary approaches each other. This study retrospectively analyzed our experience with endovascular and microsurgi...
journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2008.43.1.21
更新日期：2008-01-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2016.59.3.276
更新日期：2016-05-01 00:00:00
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2012.51.3.182
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journal_title：Journal of Korean Neurosurgical Society
pub_type： 杂志文章
doi：10.3340/jkns.2010.48.1.37
更新日期：2010-07-01 00:00:00
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pub_type：
doi：10.3340/jkns.2010.48.2.173
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