当前位置： SCI文献检索 > PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA期刊下所有文献 > Imaging prior information in the brain.

Imaging prior information in the brain.

Abstract：

:In making sense of the visual world, the brain's processing is driven by two factors: the physical information provided by the eyes ("bottom-up" data) and the expectancies driven by past experience ("top-down" influences). We use degraded stimuli to tease apart the effects of bottom-up and top-down processes because they are easier to recognize with prior knowledge of undegraded images. Using machine learning algorithms, we quantify the amount of information that brain regions contain about stimuli as the subject learns the coherent images. Our results show that several distinct regions, including high-level visual areas and the retinotopic cortex, contain more information about degraded stimuli with prior knowledge. Critically, these regions are separate from those that exhibit classical priming, indicating that top-down influences are more than feature-based attention. Together, our results show how the neural processing of complex imagery is rapidly influenced by fleeting experiences.

journal_name

Proc Natl Acad Sci U S A

journal_title

Proceedings of the National Academy of Sciences of the United States of America

authors

Gorlin S,Meng M,Sharma J,Sugihara H,Sur M,Sinha P

doi

10.1073/pnas.1111224109

subject

Has Abstract

pub_date

2012-05-15 00:00:00

pages

7935-40

issue

20

eissn

0027-8424

issn

1091-6490

pii

1111224109

journal_volume

109

pub_type

杂志文章

相关文献

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA文献大全
  • Synergistic action of glucocorticoid and estradiol responsive elements.

    abstract：:Modulation of gene expression by steroid hormones is mediated by receptor proteins that associate with regulatory elements of responsive genes upon binding the hormone ligand. The finding that two glucocorticoid responsive elements act cooperatively to stimulate transcription of the tyrosine aminotransferase gene prom...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.85.20.7526

    authors： Ankenbauer W,Strähle U,Schütz G

    更新日期：1988-10-01 00:00:00

  • Loss of CDX1 expression in colorectal carcinoma: promoter methylation, mutation, and loss of heterozygosity analyses of 37 cell lines.

    abstract：:Expression of the homeobox protein CDX1 is lost or reduced in a significant proportion of colorectal carcinomas (CRCs) but the underlying mechanism for this is unclear. We have demonstrated absence of CDX1 mRNA expression in 7 of 37 CRC cell lines and shown that all 7 cell lines have a methylated CDX1 promoter. Twenty...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.0307190101

    authors： Wong NA,Britton MP,Choi GS,Stanton TK,Bicknell DC,Wilding JL,Bodmer WF

    更新日期：2004-01-13 00:00:00

  • The A+T-rich genome of Herpesvirus saimiri contains a highly conserved gene for thymidylate synthase.

    abstract：:Herpesvirus saimiri (HVS) is the prototype member of a distinctive subset of lymphotropic herpesviruses (the gamma 2 subgroup) with A+T-rich coding sequences. In this paper, we show that cells productively infected with HVS contain high concentrations of a virus-specified thymidylate synthase (5,10-methylenetetrahydro...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.83.11.3604

    authors： Honess RW,Bodemer W,Cameron KR,Niller HH,Fleckenstein B,Randall RE

    更新日期：1986-06-01 00:00:00

  • MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells.

    abstract：:Canonical Wnt signaling plays an important role in development and disease, regulating transcription of target genes and stabilizing many proteins phosphorylated by glycogen synthase kinase 3 (GSK3). We observed that the MiT family of transcription factors, which includes the melanoma oncogene MITF (micropthalmia-asso...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1424576112

    authors： Ploper D,Taelman VF,Robert L,Perez BS,Titz B,Chen HW,Graeber TG,von Euw E,Ribas A,De Robertis EM

    更新日期：2015-02-03 00:00:00

  • Activity-based probes for proteomic profiling of histone deacetylase complexes.

    abstract：:Histone deacetylases (HDACs) are key regulators of gene expression that require assembly into larger protein complexes for activity. Efforts to understand how associated proteins modulate the function of HDACs would benefit from new technologies that evaluate HDAC activity in native biological systems. Here, we descri...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.0608659104

    authors： Salisbury CM,Cravatt BF

    更新日期：2007-01-23 00:00:00

  • Synthesis and secretion of proteins resembling platelet-derived growth factor by human glioblastoma and fibrosarcoma cells in culture.

    abstract：:Immunoprecipitation of proteins extracted from metabolically labeled human glioblastoma and fibrosarcoma cells with antiserum to platelet-derived growth factor (PDGF) showed that these cells express and secrete proteins that are recognized specifically by the antiserum. The molecular masses of immunoprecipitated prote...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.82.8.2404

    authors： Pantazis P,Pelicci PG,Dalla-Favera R,Antoniades HN

    更新日期：1985-04-01 00:00:00

  • Integration of responses within and across Arabidopsis natural accessions uncovers loci controlling root systems architecture.

    abstract：:Phenotypic plasticity is presumed to be involved in adaptive change toward species diversification. We thus examined how candidate genes underlying natural variation across populations might also mediate plasticity within an individual. Our implementation of an integrative "plasticity space" approach revealed that the...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1305883110

    authors： Rosas U,Cibrian-Jaramillo A,Ristova D,Banta JA,Gifford ML,Fan AH,Zhou RW,Kim GJ,Krouk G,Birnbaum KD,Purugganan MD,Coruzzi GM

    更新日期：2013-09-10 00:00:00

  • Mapping multisensory parietal face and body areas in humans.

    abstract：:Detection and avoidance of impending obstacles is crucial to preventing head and body injuries in daily life. To safely avoid obstacles, locations of objects approaching the body surface are usually detected via the visual system and then used by the motor system to guide defensive movements. Mediating between visual ...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1207946109

    authors： Huang RS,Chen CF,Tran AT,Holstein KL,Sereno MI

    更新日期：2012-10-30 00:00:00

  • Distinct frontal systems for response inhibition, attentional capture, and error processing.

    abstract：:Stopping an action in response to an unexpected event requires both that the event is attended to, and that the action is inhibited. Previous neuroimaging investigations of stopping have failed to adequately separate these cognitive elements. Here we used a version of the widely used Stop Signal Task that controls for...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1000175107

    authors： Sharp DJ,Bonnelle V,De Boissezon X,Beckmann CF,James SG,Patel MC,Mehta MA

    更新日期：2010-03-30 00:00:00

  • Human apolipoprotein E expression in Escherichia coli: structural and functional identity of the bacterially produced protein with plasma apolipoprotein E.

    abstract：:Human apolipoprotein E (apoE) was produced in Escherichia coli by transforming cells with an expression vector containing a reconstructed apoE cDNA, a lambda PL promoter regulated by the thermolabile cI repressor, and a ribosomal binding site derived from the lambda cII or the E. coli beta-lactamase gene. Transformed ...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.82.24.8696

    authors： Vogel T,Weisgraber KH,Zeevi MI,Ben-Artzi H,Levanon AZ,Rall SC Jr,Innerarity TL,Hui DY,Taylor JM,Kanner D

    更新日期：1985-12-01 00:00:00

  • Evidence for circularization of the avian oncornavirus RNA genome during proviral DNA synthesis from studies of reverse transcription in vitro.

    abstract：:The RNA-directed DNA polymerase (deoxynucleosidetriphosphate:DNA deoxynucleotidyltransferase EC 2.7.7.7) of avian oncornavirus requires a tryptophan tRNA (tRNATrp) primer molecule located close to the 5' end of the viral RNA genome for the initiation of DNA synthesis in vitro. In this communication we demonstrate that...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.73.4.1329

    authors： Collett MS,Faras AJ

    更新日期：1976-04-01 00:00:00

  • Two mammalian heat shock proteins, HSP90 and HSP100, are actin-binding proteins.

    abstract：:Two high molecular weight heat shock proteins, HSP90 (Mr, 90,000) and HSP100 (Mr, 100,000), were separately purified from extracts of cultured cells of a mouse lymphoma cell line, L5178Y. Both of the HSPs exist in homodimeric form under physiological conditions. Their physicochemical properties are quite similar to ea...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.83.21.8054

    authors： Koyasu S,Nishida E,Kadowaki T,Matsuzaki F,Iida K,Harada F,Kasuga M,Sakai H,Yahara I

    更新日期：1986-11-01 00:00:00

  • Dominant-negative action of the jimpy mutation in mice complemented with an autosomal transgene for myelin proteolipid protein.

    abstract：:Mutations in genes encoding membrane proteins have been associated with cell death of unknown cause from invertebrate development to human degenerative diseases. A point mutation in the gene for myelin proteolipid protein (PLP) underlies oligodendrocyte death and dysmyelination in jimpy mice, an accurate model for Pel...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.92.10.4447

    authors： Schneider AM,Griffiths IR,Readhead C,Nave KA

    更新日期：1995-05-09 00:00:00

  • Differential effects of ethanol antagonism and neuroprotection in peptide fragment NAPVSIPQ prevention of ethanol-induced developmental toxicity.

    abstract：:NAPVSIPQ (NAP), an active fragment of the glial-derived activity-dependent neuroprotective protein, is protective at femtomolar concentrations against a wide array of neural insults and prevents ethanol-induced fetal wastage and growth retardation in mice. NAP also antagonizes ethanol inhibition of L1-mediated cell ad...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1331636100

    authors： Wilkemeyer MF,Chen SY,Menkari CE,Brenneman DE,Sulik KK,Charness ME

    更新日期：2003-07-08 00:00:00

  • African origin of human-specific polymorphic Alu insertions.

    abstract：:Alu elements are a family of interspersed repeats that have mobilized throughout primate genomes by retroposition from a few "master" genes. Among the 500,000 Alu elements in the human genome are members of the human-specific subfamily that are not fixed in the human species; that is, not all chromosomes carry an Alu ...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.91.25.12288

    authors： Batzer MA,Stoneking M,Alegria-Hartman M,Bazan H,Kass DH,Shaikh TH,Novick GE,Ioannou PA,Scheer WD,Herrera RJ

    更新日期：1994-12-06 00:00:00

  • Blocking S-adenosylmethionine synthesis in yeast allows selenomethionine incorporation and multiwavelength anomalous dispersion phasing.

    abstract：:Saccharomyces cerevisiae is an ideal host from which to obtain high levels of posttranslationally modified eukaryotic proteins for x-ray crystallography. However, extensive replacement of methionine by selenomethionine for anomalous dispersion phasing has proven intractable in yeast. We report a general method to inco...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.0610337104

    authors： Malkowski MG,Quartley E,Friedman AE,Babulski J,Kon Y,Wolfley J,Said M,Luft JR,Phizicky EM,DeTitta GT,Grayhack EJ

    更新日期：2007-04-17 00:00:00

  • Facilitating and nonfacilitating synapses on pyramidal cells: a correlation between physiology and morphology.

    abstract：:Pyramidal cells in piriform cortex receive excitatory inputs from two different sources that are segregated onto adjacent segments of their apical dendrites. The present studies show that excitatory postsynaptic potentials (EPSPs) evoked by primary olfactory tract afferents that terminate on distal apical segments dis...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.83.4.1115

    authors： Bower JM,Haberly LB

    更新日期：1986-02-01 00:00:00

  • Apolipoprotein E and Alzheimer disease.

    abstract：:Inheritance of specific apolipoprotein E (apoE) alleles determines, in large part, the risk and mean age of onset of late-onset familial and sporadic Alzheimer disease. The mechanism by which the apoE isoforms differentially contribute to disease expression is, however, unknown. Isoform-specific differences have been ...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章,评审

    doi：10.1073/pnas.92.11.4725

    authors： Strittmatter WJ,Roses AD

    更新日期：1995-05-23 00:00:00

  • Negative charge at the casein kinase II phosphorylation site is important for transformation but not for Rb protein binding by the E7 protein of human papillomavirus type 16.

    abstract：:The human papillomavirus E7 protein is phosphorylated at the two serines in positions 31/32, which are part of a consensus sequence for casein kinase II (CKII). In this study, we have investigated the effect of CKII phosphorylation site mutations, all of which lead to unphosphorylated E7 proteins. The replacement of t...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.88.12.5187

    authors： Firzlaff JM,Lüscher B,Eisenman RN

    更新日期：1991-06-15 00:00:00

  • The long cytoplasmic tail of gp41 is required in a cell type-dependent manner for HIV-1 envelope glycoprotein incorporation into virions.

    abstract：:Lentiviruses, including HIV-1, have transmembrane envelope (Env) glycoproteins with cytoplasmic tails that are quite long compared with those of other retroviruses. However, mainly because of the lack of biochemical studies performed in cell types that are targets for HIV-1 infection, no clear consensus exists regardi...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.97.1.343

    authors： Murakami T,Freed EO

    更新日期：2000-01-04 00:00:00

  • Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptor.

    abstract：:NKp46 is a cell surface receptor expressed on natural killer (NK) cells, on a minute subset of T cells, and on a population of innate lymphoid cells that produce IL-22 and express the transcription factor retinoid-related orphan receptor (ROR)-γt, referred to as NK cell receptor (NKR)(+)ROR-γt(+) cells. Here we descri...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1112064108

    authors： Narni-Mancinelli E,Chaix J,Fenis A,Kerdiles YM,Yessaad N,Reynders A,Gregoire C,Luche H,Ugolini S,Tomasello E,Walzer T,Vivier E

    更新日期：2011-11-08 00:00:00

  • Antiinflammatory cAMP signaling and cell migration genes co-opted by the anthrax bacillus.

    abstract：:Bacillus anthracis, the etiologic agent of anthrax, avoids immune surveillance and commandeers host macrophages as a vehicle for lymphatic spreading. Here, we show that B. anthracis edema toxin (ET), via its adenylyl cyclase activity, dramatically increases the motility of infected macrophages and the expression of va...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.0800105105

    authors： Kim C,Wilcox-Adelman S,Sano Y,Tang WJ,Collier RJ,Park JM

    更新日期：2008-04-22 00:00:00

  • Characterization of a murine type II sodium-phosphate cotransporter expressed in mammalian small intestine.

    abstract：:An isoform of the mammalian renal type II Na/Pi-cotransporter is described. Homology of this isoform to described mammalian and nonmammalian type II cotransporters is between 57 and 75%. Based on major diversities at the C terminus, the new isoform is designed as type IIb Na/Pi-cotransporter. Na/Pi-cotransport mediate...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.95.24.14564

    authors： Hilfiker H,Hattenhauer O,Traebert M,Forster I,Murer H,Biber J

    更新日期：1998-11-24 00:00:00

  • The role of chromosomal instability in tumor initiation.

    abstract：:Chromosomal instability (CIN) is a defining characteristic of most human cancers. Mutation of CIN genes increases the probability that whole chromosomes or large fractions of chromosomes are gained or lost during cell division. The consequence of CIN is an imbalance in the number of chromosomes per cell (aneuploidy) a...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.202617399

    authors： Nowak MA,Komarova NL,Sengupta A,Jallepalli PV,Shih IeM,Vogelstein B,Lengauer C

    更新日期：2002-12-10 00:00:00

  • Role of cell surface immunoglobulin in B-lymphocyte activation.

    abstract：:The role of cell surface immunoglobulin in helper T-cell-dependent B-cell activation was analyzed using a B-cell lymphoma, CH12, with known antigen specificity and activation properties similar to those of a resting B cell. Two sources of helper T cells were used, both selected such that they interact with H-2-encoded...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.81.8.2466

    authors： LoCascio NJ,Haughton G,Arnold LW,Corley RB

    更新日期：1984-04-01 00:00:00

  • Neuroimaging analyses of human working memory.

    abstract：:We review a program of research that uses neuroimaging techniques to determine the functional and neural architecture of human working memory. A first set of studies indicates that verbal working memory includes a storage component, which is implemented neurally by areas in the left-hemisphere posterior parietal corte...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章,评审

    doi：10.1073/pnas.95.20.12061

    authors： Smith EE,Jonides J

    更新日期：1998-09-29 00:00:00

  • Global ensemble projections reveal trophic amplification of ocean biomass declines with climate change.

    abstract：:While the physical dimensions of climate change are now routinely assessed through multimodel intercomparisons, projected impacts on the global ocean ecosystem generally rely on individual models with a specific set of assumptions. To address these single-model limitations, we present standardized ensemble projections...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1900194116

    authors： Lotze HK,Tittensor DP,Bryndum-Buchholz A,Eddy TD,Cheung WWL,Galbraith ED,Barange M,Barrier N,Bianchi D,Blanchard JL,Bopp L,Büchner M,Bulman CM,Carozza DA,Christensen V,Coll M,Dunne JP,Fulton EA,Jennings S,Jones MC,

    更新日期：2019-06-25 00:00:00

  • Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas.

    abstract：:CYP1B1-null mice, created by targeted gene disruption in embryonic stem cells, were born at the expected frequency from heterozygous matings with no observable phenotype, thus establishing that CYP1B1 is not required for mouse development. CYP1B1 was not detectable in cultured embryonic fibroblast (EF) or in different...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.96.5.1977

    authors： Buters JT,Sakai S,Richter T,Pineau T,Alexander DL,Savas U,Doehmer J,Ward JM,Jefcoate CR,Gonzalez FJ

    更新日期：1999-03-02 00:00:00

  • Myelin sheath structure and regeneration in peripheral nerve injury repair.

    abstract：:Observing the structure and regeneration of the myelin sheath in peripheral nerves following injury and during repair would help in understanding the pathogenesis and treatment of neurological diseases caused by an abnormal myelin sheath. In the present study, transmission electron microscopy, immunofluorescence stain...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1910292116

    authors： Liu B,Xin W,Tan JR,Zhu RP,Li T,Wang D,Kan SS,Xiong DK,Li HH,Zhang MM,Sun HH,Wagstaff W,Zhou C,Wang ZJ,Zhang YG,He TC

    更新日期：2019-10-29 00:00:00

  • Productive nonlytic human immunodeficiency virus type 1 replication in a newly established human leukemia cell line.

    abstract：:We have isolated a lymphoid cell line, MDS, from the pleural exudate of a patient with chronic myelomonocytic leukemia. The cells are biphenotypic, containing various T-cell and myeloid markers, and are surface negative for CD4 and CD8 but have low CD4 mRNA. The cells grow in suspension with a doubling time of 15 hr, ...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.89.21.9996

    authors： Banerjee R,Bekesi JG,Tarcsafalvi A,Sperber K,Deak G,Choi HS,Paronetto F,Holland JF,Acs G

    更新日期：1992-11-01 00:00:00