当前位置： SCI文献检索 > JOURNAL OF ASSISTED REPRODUCTION AND GENETICS期刊下所有文献 > Delivery of a chromosomally normal child from an oocyte with reciprocal aneuploid polar bodies.

Delivery of a chromosomally normal child from an oocyte with reciprocal aneuploid polar bodies.

Abstract：

PURPOSE:To demonstrate that a euploid embryo derived from an oocyte with reciprocal aneuploid polar bodies is capable of producing a chromosomally normal child. METHODS:A case report of maternal MI error compensation where single nucleotide polymorphism (SNP) microarray based comprehensive chromosome screening (CCS) was performed on the 1st and 2nd polar body, the resulting embryo, and newborn DNA. RESULTS:CCS performed after embryo transfer identified a chromosomally normal embryo that resulted from an oocyte with reciprocal aneuploid polar bodies. The first polar body was found to be missing a single chromatid derived from chromosome 21 and the second polar body possessed an extra chromatid derived from chromosome 21. Compensation of the maternal meiotic error was verified by CCS analysis of a trophectoderm biopsy from the resulting blastocyst which was euploid for all 23 pairs of chromosomes. DNA fingerprinting and CCS of the resulting newborn confirmed a chromosomally normal child, demonstrating the developmental potential of an oocyte with reciprocal aneuploid polar bodies. CONCLUSIONS:This is the first case report demonstrating the reproductive potential of a chromosomally normal embryo derived from an oocyte which had undergone meiosis I error. Systematic investigation into the frequency of meiosis I error compensation and the negative predictive value of polar body aneuploidy screening for reproductive potential should be conducted in order to confirm clinical relevance.

journal_name

J Assist Reprod Genet

journal_title

Journal of assisted reproduction and genetics

authors

Scott RT Jr,Treff NR,Stevens J,Forman EJ,Hong KH,Katz-Jaffe MG,Schoolcraft WB

doi

10.1007/s10815-012-9746-6

subject

Has Abstract

pub_date

2012-06-01 00:00:00

pages

533-7

issue

6

eissn

1058-0468

issn

1573-7330

journal_volume

29

pub_type

杂志文章

相关文献

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS文献大全
  • Decreased expression of MRE11 and RAD50 in testes from humans with spermatogenic failure.

    abstract：PURPOSE:To assess testicular mRNA and protein expression levels of MRE11 and RAD50 in human azoospermia patients. METHODS:Patients diagnosed with maturation arrest at the spermatocyte stage (MA) and Sertoli cell-only syndrome (SCOS) were recruited through diagnostic testicular biopsy. Patients with normal spermatogene...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-019-01686-5

    authors： Hu M,Li L,Liu S,Lou Y,Wang L,Le F,Li H,Wang Q,Lou H,Wang N,Jin F

    更新日期：2020-02-01 00:00:00

  • Do young women with unexplained infertility show manifestations of decreased ovarian reserve?

    abstract：PURPOSE:To investigate whether unexplained infertility at a young age demonstrates manifestations of decreased ovarian reserve. METHODS:A total of 100 women were divided into two equally sized groups. The study group comprised women aged ≤ 37 years diagnosed with unexplained infertility, and the control group included...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-019-01467-0

    authors： Abrahami N,Izhaki I,Younis JS

    更新日期：2019-06-01 00:00:00

  • Natural conception after age 45 in Bedouin women, a uniquely fertile population.

    abstract：PURPOSE:Women conceiving naturally and delivering after age 45 are an exceptionally fertile population that may serve as a model to identify factors associated with delayed reproductive aging. This work studies this phenomenon in Bedouin women. METHODS:The study is an observational retrospective analysis of all Bedoui...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-006-9058-9

    authors： Gielchinsky Y,Mazor M,Simon A,Mor-Yossef S,Laufer N

    更新日期：2006-07-01 00:00:00

  • Preparation of endometrium for frozen embryo replacement cycles: a systematic review and meta-analysis.

    abstract：PURPOSE:The purpose of this study was to evaluate the best protocol to prepare endometrium for frozen embryo replacement (FER) cycles. METHODS:This study is a systematic review and meta-analysis. Following PubMed and OvidSP search, a total of 1166 studies published after 1990 were identified following removal of dupli...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,meta分析,评审

    doi：10.1007/s10815-016-0787-0

    authors： Yarali H,Polat M,Mumusoglu S,Yarali I,Bozdag G

    更新日期：2016-10-01 00:00:00

  • Exposure of preimplantation embryos to platelet-activating factor increases birth rate.

    abstract：PROBLEM:Platelet-activating factor (PAF) plays a significant role in fertility. Preimplantation stage embryos produce PAF (ePAF) which is required for development. PAF's mechanism of action is receptor-mediated and its presence has been reported in the developing mouse and human embryo. Exposure of preimplantation stag...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1023/b:jarg.0000043703.73207.25

    authors： Roudebush WE,Massey JB,Kort HI,Elsner CW,Toledo AA,Mitchell-Leef D,Shapiro DB

    更新日期：2004-08-01 00:00:00

  • Ovum donation--an overview.

    abstract：:Ovum donation is now an integral part of the management of infertility, providing a solution for patients previously considered permanently infertile. The indications now include not only patients with premature ovarian failure, but also patients who are carriers of genetic disorders, patients with repeated failures i...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,评审

    doi：10.1007/BF01207729

    authors： Benshushan A,Schenker JG

    更新日期：1993-02-01 00:00:00

  • Female infertility, infertility-associated diagnoses, and comorbidities: a review.

    abstract：PURPOSE:The purpose of the study is to evaluate existing literature for possible associations between female infertility, infertility-associated diagnoses, and the following areas of disease: psychiatric disorders, breast cancer, ovarian cancer, endometrial cancer, cardiovascular disease, and metabolic dysfunction. ME...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,评审

    doi：10.1007/s10815-016-0836-8

    authors： Hanson B,Johnstone E,Dorais J,Silver B,Peterson CM,Hotaling J

    更新日期：2017-02-01 00:00:00

  • The contribution of mitochondrial function to reproductive aging.

    abstract：PURPOSE:The number of women attempting to conceive between the ages of 36 and 44 has increased significantly in the last decade. While it is well established that women's reproductive success dramatically declines with age, the underlying physiological changes responsible for this phenomenon are not well understood. Wi...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,评审

    doi：10.1007/s10815-011-9588-7

    authors： Bentov Y,Yavorska T,Esfandiari N,Jurisicova A,Casper RF

    更新日期：2011-09-01 00:00:00

  • Extracellular microRNA profiling in human follicular fluid: new biomarkers in female reproductive potential.

    abstract：:MicroRNAs (miRNAs) are small, about 22 nucleotides, non-coding RNAs which regulate a wide range of gene expression during post-transcriptional stage. They are released into intra- and extracellular microenvironments and play vital roles in different physiological and pathological pathways. Due to easy accessibility, d...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,评审

    doi：10.1007/s10815-020-01860-0

    authors： Qasemi M,Amidi F

    更新日期：2020-08-01 00:00:00

  • Improvement of IVF outcome in poor responders by discontinuation of GnRH analogue during the gonadotropin stimulation phase--a function of improved embryo quality.

    abstract：PURPOSE:To assess the efficacy of a protocol involving the discontinuation of the GnRH analogue at the mid-phase of ovarian stimulation for IVF in patients with a previous poor response. METHODS:Prospective case-control evaluation compared with same patient's previous performance. Thirty-six patients enrolled in an IV...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 临床试验,杂志文章

    doi：10.1023/a:1009476411762

    authors： Schachter M,Friedler S,Raziel A,Strassburger D,Bern O,Ron-el R

    更新日期：2001-04-01 00:00:00

  • Identification of biochemical differences between different forms of male infertility by nuclear magnetic resonance (NMR) spectroscopy.

    abstract：PURPOSE:The aim of this study was to analyze the seminal plasma of patients with idiopathic/male factor infertility and healthy controls with proven fertility by NMR spectroscopy, with a hope of establishing difference in biomarker profiles, if any, between the groups. METHODS:A total of 103 subjects visiting the infe...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-014-0282-4

    authors： Jayaraman V,Ghosh S,Sengupta A,Srivastava S,Sonawat HM,Narayan PK

    更新日期：2014-09-01 00:00:00

  • Closed vitrification of human oocytes and blastocysts: outcomes from a series of clinical cases.

    abstract：PURPOSE:High survival rates and clinical outcomes similar to those from fresh oocytes and blastocysts have been observed with open oocyte vitrification systems. It has been suggested that the extremely fast cooling rates that are only achieved with open systems are necessary for human oocyte and blastocyst vitrificatio...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-016-0748-7

    authors： Gook DA,Choo B,Bourne H,Lewis K,Edgar DH

    更新日期：2016-09-01 00:00:00

  • Epidermal growth factor (EGF) receptor localization in cultured human granulosa lutein cells and the stimulation of progesterone production by EGF and transforming growth factor-alpha (TGF-alpha).

    abstract：PURPOSE:The purpose of this study was to investigate the expression of EGF receptor (EGF-R) in human granulosa cells undergoing luteinization and progesterone production by these cells in response to EGF an TGF-alpha alone or in combination with luteinizing hormone (LH). Granulosa cells were obtained from IF patients f...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/BF02212900

    authors： Tekpetey FR,Daniel SA,Yuzpe A

    更新日期：1995-11-01 00:00:00

  • The influences of weather on patients with different ovarian responses in the treatment of assisted reproductive technology.

    abstract：PURPOSE:The purpose of this study was to evaluate the influences of tropical weather on patients with different ovarian responses in the treatment of assisted reproductive technology. METHODS:Six-hundred fourty-seven women underwent their first treatment cycles were retrospectively analyzed. Patients received embryo t...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-005-4922-6

    authors： Chang SY,Lan KC,Chen CW,Huang FJ,Tsai MY,Chang CY

    更新日期：2005-05-01 00:00:00

  • Association between apolipoprotein E gene polymorphism and the risk of recurrent pregnancy loss: a meta-analysis.

    abstract：PURPOSE:The association between apolipoprotein E (ApoE) gene polymorphism and the risk of recurrent pregnancy loss (RPL) remains controversial. The present meta-analysis was performed to derive a precise estimate of the relationship. METHOD(S):We searched the PubMed, Embase, and Web of Science data- bases for studies ...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,meta分析

    doi：10.1007/s10815-013-0118-7

    authors： Meng HX,Qi MG,Yi YY,Liu YP

    更新日期：2013-12-01 00:00:00

  • Stress and reproductive failure: past notions, present insights and future directions.

    abstract：PROBLEM:Maternal stress perception is frequently alleged as a cause of infertility, miscarriages, late pregnancy complications or impaired fetal development. The purpose of the present review is to critically assess the biological and epidemiological evidence that considers the plausibility of a stress link to human re...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,评审

    doi：10.1007/s10815-008-9206-5

    authors： Nakamura K,Sheps S,Arck PC

    更新日期：2008-02-01 00:00:00

  • Sequential FISH allows the determination of the segregation outcome and the presence of numerical anomalies in spermatozoa from a t(1;8;2)(q42;p21;p15) carrier.

    abstract：PURPOSE:To find out the meiotic segregation behaviour of the t(1;8;2)(q42;p21;p15), to evaluate the occurrence of interchromosomal effects, and to determine whether there is an accumulation of unbalanced products in aneuploid/diploid gametes. METHODS:A sequential FISH protocol based on two successive hybridization rou...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-013-0063-5

    authors： Godo A,Blanco J,Vidal F,Parriego M,Boada M,Anton E

    更新日期：2013-09-01 00:00:00

  • Effects of supplement therapy on sperm parameters, protamine content and acrosomal integrity of varicocelectomized subjects.

    abstract：PURPOSE:Surgical repair of varicocele has long been a procedure to correct spermatogenesis. However, the outcome has been reported to be inadequate. We combined varicocelectomy with supplement therapy to evaluate the concurrent effect of these procedures. METHODS:A prospective randomized controlled study was undertake...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/s10815-013-9961-9

    authors： Azizollahi G,Azizollahi S,Babaei H,Kianinejad M,Baneshi MR,Nematollahi-mahani SN

    更新日期：2013-04-01 00:00:00

  • Lower follicular n-3 polyunsaturated fatty acid levels are associated with a better response to ovarian stimulation.

    abstract：OBJECTIVES:To analyze in detail the fatty acid (FA) composition of follicular fluid (FF) from two-sized follicles at oocyte retrieval and to determine associations of the FAs from large follicles with the woman's age and the response to ovarian stimulation. DESIGN:Observational study. SETTING:University and fertility...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-018-1384-1

    authors： Ruiz-Sanz JI,Pérez-Ruiz I,Meijide S,Ferrando M,Larreategui Z,Ruiz-Larrea MB

    更新日期：2019-03-01 00:00:00

  • Oocyte cryopreservation for women with GATA2 deficiency.

    abstract：PURPOSE:To describe controlled ovarian stimulation (COS) in a population of women with GATA2 deficiency, a genetic bone marrow failure syndrome, prior to allogeneic hematopoietic stem cell transplant METHODS: This is a retrospective case series of nine women with GATA2 deficiency who underwent oocyte preservation at a ...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-018-1146-0

    authors： Zolton JR,Parikh TP,Hickstein DD,Holland SM,Hill MJ,DeCherney AH,Wolff EF

    更新日期：2018-07-01 00:00:00

  • Is AMH a regulator of follicular atresia?

    abstract：:We discuss the hypothesis that AMH is an intraovarian regulator that inhibits follicular atresia within the human ovary. Several indirect lines of evidence derived from clinical and basic science studies in a variety of different patient populations and model systems collectively support this hypothesis. Evidence pres...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,评审

    doi：10.1007/s10815-014-0328-7

    authors： Seifer DB,Merhi Z

    更新日期：2014-11-01 00:00:00

  • Endometriosis does not affect live birth rates of patients submitted to assisted reproduction techniques: analysis of the Latin American Network Registry database from 1995 to 2011.

    abstract：PURPOSE:The purpose of this study is to compare the results of ART treatment in patients with and without endometriosis in a large cohort of patients from different centers over an extented period of time. METHODS:This retrospective study is using data from patients undergoing 27,294 cycles of IVF/ICSI treatment betwe...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-018-1214-5

    authors： Murta M,Machado RC,Zegers-Hochschild F,Checa MA,Sampaio M,Geber S

    更新日期：2018-08-01 00:00:00

  • Reference gene selection for real-time quantitative PCR analysis on ovarian cryopreservation by vitrification in mice.

    abstract：PURPOSE:To ensure the correct interpretation of the results of quantitative real-time reverse transcription-polymerase chain reaction (qRT-PCR) from ovarian tissue cryopreserved by vitrification, it is critical to normalize expression levels to a reference gene with stable messenger RNA (mRNA) expression in the vitrifi...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-015-0503-5

    authors： Yuanyuan S,Qin S,Rongrong X,Yujing G,Chengbin P,Jianjun M,Yanzhou Y,Xiuying P

    更新日期：2015-08-01 00:00:00

  • Worldwide live births following the transfer of chromosomally "Abnormal" embryos after PGT/A: results of a worldwide web-based survey.

    abstract：PURPOSE:Preimplantation genetic testing for aneuploidy (PGT-A) has become increasingly controversial since normal euploid births have been reported following transfer of embryos diagnosed as "abnormal." There is an increasing trend in transferring "abnormal" embryos; but it is still unknown how many IVF centers transfe...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-019-01510-0

    authors： Patrizio P,Shoham G,Shoham Z,Leong M,Barad DH,Gleicher N

    更新日期：2019-08-01 00:00:00

  • Recent trends in embryo disposition choices made by patients following in vitro fertilization.

    abstract：PURPOSE:To assess longitudinal trends in in vitro fertilization (IVF) patients' choices for disposing of cryopreserved embryos. METHODS:This is a retrospective cohort study of embryo disposition forms submitted between January 2000 and February 2020 at a university-based fertility clinic. Primary outcome was dispositi...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-020-01927-y

    authors： Alexander VM,Riley JK,Jungheim ES

    更新日期：2020-11-01 00:00:00

  • Beneficial effect of desialylated erythropoietin administration on the frozen-thawed canine ovarian xenotransplantation.

    abstract：PURPOSE:The main drawback of ovarian cryopreservation followed by transplantation is that a large proportion of follicles are lost after transplantation. Thus, effects of erythropoietin (EPO) and desialylated EPO administration on the frozen-thawed canine ovarian xenotransplantation were examined. METHODS:The protecti...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-008-9271-9

    authors： Suzuki H,Ishijima T,Maruyama S,Yanagimoto Ueta Y,Abe Y,Saitoh H

    更新日期：2008-11-01 00:00:00

  • Intra- and inter-individual variability of fatty acid composition of the follicular fluid in a cohort of 23 women undergoing assisted reproductive treatment.

    abstract：PURPOSE:To examine the intra- and inter-individual variability in fatty acid composition of follicular fluid (FF) of 23 patients undergoing assisted reproductive treatment. METHODS:The average coefficient of variation within each patient (CVw) and intra-class correlation coefficient (ICC) values of FF fatty acid compo...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-019-01669-6

    authors： Liu YJ,Vlaeminck B,Tilleman K,Chouinard PY,Gervais R,De Sutter P,Fievez V

    更新日期：2020-03-01 00:00:00

  • Ovarian reserve evaluation: state of the art.

    abstract：PURPOSE:Revise role of hormonal basal and dynamic tests, as well as ultrasonographic measures as ovarian reserve markers, in order to provide better counseling to subfertile couples. METHODS:Review of publications on the topic, with an emphasis on recent well designed articles. RESULTS:Currently available ovarian res...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,评审

    doi：10.1007/s10815-008-9241-2

    authors： de Carvalho BR,Rosa e Silva AC,Rosa e Silva JC,dos Reis RM,Ferriani RA,Silva de Sá MF

    更新日期：2008-07-01 00:00:00

  • Microinsemination techniques for the treatment of patients suffering agenesia of the vas deferens.

    abstract：:Thirty cycles of microsurgical epididymal sperm aspiration were performed on 27 patients presenting agenesia of the vas deferens. Two techniques of microinsemination were used, depending on the quality of the sperm preparation: subzonal sperm microinjection and microdroplet insemination. The results obtained by both m...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/BF02070149

    authors： Gianaroli L,Magli MC,Colpi G,Vitali G,Fortini D,Negri L,Ferraretti AP

    更新日期：1996-04-01 00:00:00

  • Maternal physical activity and sedentary behaviour before and during in vitro fertilization treatment: a longitudinal study exploring the associations with controlled ovarian stimulation and pregnancy outcomes.

    abstract：PURPOSE:To evaluate the association of objectively measured physical activity (PA) and sedentary behaviour before and during in vitro fertilization (IVF) with controlled ovarian stimulation (COS) and pregnancy outcomes. METHODS:This longitudinal study involved 107 infertile women undergoing IVF treatment. PA and seden...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-020-01864-w

    authors： Sõritsa D,Mäestu E,Nuut M,Mäestu J,Migueles JH,Läänelaid S,Ehrenberg A,Sekavin A,Sõritsa A,Salumets A,Ortega FB,Altmäe S

    更新日期：2020-08-01 00:00:00