Abstract:
PURPOSE:The objectives of the study were to analyze the tumor shrinkage pattern on magnetic resonance imaging (MRI) after neoadjuvant chemotherapy and to evaluate whether there is any difference in shrinkage pattern between pathological responder and nonresponder groups. In addition, we wanted to compare tumor diameter obtained from MRI with histological diameter according to the tumor shrinkage pattern. METHODS:Between July 2008 and December 2010, 55 consecutive patients (56 lesions) with pathologically proven breast cancer who underwent neoadjuvant chemotherapy followed by surgery were retrospectively enrolled. The shrinkage pattern was classified into 4 categories: I (concentric shrinkage without surrounding lesion), II (concentric shrinkage with surrounding lesions), III (shrinkage with residual multinodular lesions, and IV (diffuse contrast enhancement in whole quadrants). Histological regression was scored on a 5-point scale regarding tumor cellularity reduction (Miller-Payne grading system). Patients with Miller-Payne grade 1 or 2 were classified into the nonresponder group, and patients with grade 3, 4, or 5 were in the responder group. RESULTS:Of 56 lesions, pattern I was seen in 29 lesions, pattern II in 13 lesions, pattern III in 5 lesions, and pattern IV in 4 lesions. Three lesions were not visualized on MRI after neoadjuvant chemotherapy, and 2 lesions were increased in size. There was a statistically significant difference in the tumor shrinkage pattern between responder and nonresponder groups (P = 0.017). All 5 lesions with type III shrinkage pattern were found in the responder group, and all 4 lesions with pattern IV were in the nonresponder group. Magnetic resonance imaging diameter of lesions with types I, II, and IV patterns showed significant correlation with the histological diameter. Among them, the correlation factor was highest in pattern IV (ρ = 0.94, P < 0.001) followed by pattern I (ρ = 0.67, P < 0.01) and pattern II (ρ = 0.502, P = 0.08). However, in type III shrinkage pattern, tumor size measured on MRI was not significantly correlated with histological size (P = 0.87). CONCLUSIONS:Types III and I shrinkage patterns were more frequently observed in the pathological responder group, and type IV was more frequently noted in the nonresponder group. Tumor diameter measured on MRI showed strong correlation with histological diameter in lesions with types I and IV shrinkage patterns, whereas lesions with type III did not show significant correlation. Type II pattern showed similar frequencies between the 2 groups and moderate correlation between sizes obtained from MRI and histology.
journal_name
J Comput Assist Tomogrjournal_title
Journal of computer assisted tomographyauthors
Kim TH,Kang DK,Yim H,Jung YS,Kim KS,Kang SYdoi
10.1097/RCT.0b013e318246abf3subject
Has Abstractpub_date
2012-03-01 00:00:00pages
200-6issue
2eissn
0363-8715issn
1532-3145pii
00004728-201203000-00009journal_volume
36pub_type
杂志文章abstract:OBJECTIVE:The purpose of this study is to evaluate predictive factors for discriminating benign from malignant intraductal mucin-producing neoplasm (IPMN) of the pancreas on multidetector row computed tomography (MDCT). MATERIALS AND METHODS:Fifty-three patients with IPMN underwent MDCT, and the imaging and pathologic...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3180676d97
更新日期:2008-03-01 00:00:00
abstract::A system of computer programs is described which, for the first time, is able to use computerized tomographic data to automatically locate, measure, and describe anatomical structures of interest with accuracy and consistency. Input to the system consists of any digitized radiographic data. Computer assisted tomograph...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198308000-00008
更新日期:1983-08-01 00:00:00
abstract:BACKGROUND:The state-of-art motion correction algorithm is inadequate for correcting motion artifacts in coronary arteries in cardiovascular computed tomography angiography (CCTA) for children with high heart rates, and even less effective for heart structures beyond coronary arteries. PURPOSE:This study aimed to eval...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000001035
更新日期:2020-09-01 00:00:00
abstract::A method for the production of thin axial transverse sections, coronal views, and sagittal views from overlapped thick computed tomography (CT) scans has been developed. Thin slices are produced by spatially filtering the overlapped CT data using a filter that is a combination of square waves in the spatial domain. Re...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198002000-00016
更新日期:1980-02-01 00:00:00
abstract::We report the serial MR and PET/SPECT findings in a 2 1/2-year-old boy presenting with Rasmussen syndrome and highlight the close qualitative correlations between the results of the imaging modality and the functional isotopic techniques. The latter demonstrated a wider field of extension of the disease process. Routi...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199711000-00010
更新日期:1997-11-01 00:00:00
abstract:BACKGROUND AND AIMS:To prospectively determine the accuracy of liver fat quantification with magnetic resonance imaging (MRI). PATIENTS AND METHODS:The population consisted of 40 patients (mean age, 52.5 years; range, 23-78 years). The same day, all patients underwent MRI and ultrasonography-guided liver biopsy. The h...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e318199d883
更新日期:2009-09-01 00:00:00
abstract::Contrast enhancement has been studied with computed tomography in 18 patients with brain infarction. Four patients were examined on more than one occasion. A mode of contrast medium administration has been used that results in constant blood iodine concentration during the investigation. The enhancement pattern was an...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197904000-00016
更新日期:1979-04-01 00:00:00
abstract::The CT findings in hepatic involvement by Echinococcus granulosus are described. Pathognomonic signs of the hydatid nature of a cystic lesion are visualization of the cystic wall on plain CT, calcification of the cyst wall, daughter cysts, and membrane detachment. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198410000-00005
更新日期:1984-10-01 00:00:00
abstract::A method is outlined for obtaining direct longitudinal computed tomograms of the forearm using a conventional total body scanner. A case is described in which longitudinal scanning helped define a soft tissue tumor of the forearm and thereby assisted in surgical planning. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198102000-00029
更新日期:1981-02-01 00:00:00
abstract::An unusual case of isolated injury to the caudate lobe of the liver in a child is presented. The appearance of this injury is described, and its significance in relation to deep vascular structures of the porta hepatis and the portocaval space is discussed. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198805010-00038
更新日期:1988-05-01 00:00:00
abstract::Presented is a case of ureteral pseudodiverticulosis diagnosed by multidetector computed tomography (CT). Axial and coronal reformatted CT images revealed multiple small (2-4 mm) outpouchings of both ureters, characteristic of ureteral pseudodiverticulosis. The unenhanced CT also revealed a 6-mm stone at the left uret...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e318173ebd0
更新日期:2009-03-01 00:00:00
abstract::The use of magnetic resonance (MR) to preoperatively evaluate patients with primary hyperparathyroidism was assessed using a 1.5 T system and surface coil reception. Twenty-five patients with primary hyperparathyroidism were studied before surgical exploration. Axial images, 5 mm thick, were obtained from the thyroid ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198709000-00023
更新日期:1987-09-01 00:00:00
abstract::Flow phenomena occurring after the bolus injection of contrast material can simulate the presence of pathology on thoracic computed tomography. In a review of 50 dynamic scans performed after contrast medium injection, apparent filling defects in the superior vena cava were seen in 46. In four cases, retrograde fillin...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198206000-00004
更新日期:1982-06-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to describe the computed tomography (CT) findings and correlate pulmonary function tests (PFTs) of silicosis patients with emphasis on the findings in lung transplantation (LTX) recipients. METHODS:We studied the chest CT scans from 82 marble workers exposed to artificial stone dust...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000454
更新日期:2016-11-01 00:00:00
abstract::We report an unusual case of diffuse infiltration of the mesentery by amyloidosis. The CT, sonographic, and operative findings mimicked abdominal carcinomatosis. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::The CT findings in 20 patients with pulmonary hydatid disease were reviewed. Sixty-four intrapulmonary cysts were imaged, 22% of which were ruptured or complicated. Simple hydatid cysts and water-density lung cysts of other etiology may have a similar CT appearance; however, the demonstration of the cystic nature of a...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198603000-00011
更新日期:1986-03-01 00:00:00
abstract::Five cases of histologically confirmed olfactory neuroblastoma (esthesioneuroblastomas) have been studied by computed tomography (CT). Both the clinical symptoms (in particular, unilateral nasal obstruction and recurring epistaxis) and radiological findings (opacity of the paranasal sinuses) are nonspecific. Computed ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:
更新日期:1978-09-01 00:00:00
abstract:OBJECTIVE:We compared MRI with two-dimensional echocardiography (2dE) and Doppler echocardiography to determine the diagnostic role of MRI in hypertrophic cardiomyopathy (HCM). MATERIALS AND METHODS:Twenty-three patients with 2dE diagnosis of HCM were examined with MRI; 12 of 23 patients were also studied by color (cD...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199311000-00005
更新日期:1993-11-01 00:00:00
abstract:PURPOSE:The purpose of this work was to conduct an MR cholangiography study of hepatobiliary abnormalities in autosomal dominant polycystic kidney disease (ADPKD) and to correlate these abnormalities with the risk of infection. METHOD:Cystic and intrahepatic bile duct (IHBD) abnormalities identified by MR cholangiogra...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200203000-00013
更新日期:2002-03-01 00:00:00
abstract:OBJECTIVE:There is an ongoing debate about how to handle incidental findings (IF) detected in healthy individuals who participate in research-driven magnetic resonance imaging (MRI) studies. There are currently no established guidelines regarding their management. METHODS:We prospectively assessed the frequency of IF ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3181d9c2bb
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:This study evaluated the incidence and course of a hematoma occurring after femoral arterial sampling. MATERIALS AND METHODS:We studied 270 patients who underwent computed tomography (CT) including the pelvis and blood gas sampling from femoral artery using a 22-gauge needle during 2010. This population comp...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3182483c55
更新日期:2012-03-01 00:00:00
abstract::The incidence of melanoma has risen dramatically over the past several decades. Oncologists rely on the ability of radiologists to identify subtle radiographic changes representing metastatic and recurrent melanoma in uncommon locations on multidetector computed tomography (MDCT) as the front-line imaging surveillance...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/RCT.0000000000000697
更新日期:2018-05-01 00:00:00
abstract::Computed tomographic and magnetic resonance (MR) findings in a case of pseudomyxoma peritonei arising from a mucoid cystadenoma of the ovary are presented. The possible diagnostic aid of MR is discussed. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198511000-00025
更新日期:1985-11-01 00:00:00
abstract::This is the third of a series of 4 white papers that represent Expert Consensus Documents developed by the Society of Computed Body Tomography and Magnetic Resonance through its Task Force on dual-energy computed tomography. This paper, part 3, describes computed tomography angiography and thoracic, cardiac, vascular,...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000538
更新日期:2017-01-01 00:00:00
abstract::To explore the potential role of MRI in detecting cardiac allograft rejection in transplant recipients using gadolinium tetraazacyclododecane tetraacetic acid (Gd-DOTA) for contrast enhancement, we examined 7 normal healthy volunteers and 39 patients separated into three groups according to histological findings. Quan...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199303000-00012
更新日期:1993-03-01 00:00:00
abstract:OBJECTIVE:To determine the frequency and computed tomography (CT) characteristics of ovarian cysts in women of different ages. METHODS:Five hundred ninety-five contrast-enhanced CT studies performed in 430 females aged 10 or older between January 2001 and December 2006 were retrospectively reviewed. For each study, we...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3181d658a5
更新日期:2010-07-01 00:00:00
abstract::Computed tomography assessment of 634 surgically proven solitary pulmonary nodules included 12 pulmonary carcinoid tumors. Five were central (involving or directly abutting the bronchial tree), and seven were peripheral (surrounded by parenchyma). Three central and one peripheral lesion had CT numbers indicative of fo...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198903000-00010
更新日期:1989-03-01 00:00:00
abstract:PURPOSE:First-pass perfusion magnetic resonance imaging (MRI) is a promising technique for detecting ischemic heart disease. However, the diagnostic value of the method is limited by the low spatial coverage, resolution, signal-to-noise ratio (SNR), and cardiac motion-related image artifacts. A combination of sliding w...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3181e9e9dd
更新日期:2010-09-01 00:00:00
abstract::Tiazofurin is an experimental chemotherapeutic agent currently undergoing clinical evaluation. We report our results with magnetic resonance (MR) in demonstrating reversible cerebral abnormalities concurrent with the use of this drug. The abnormalities on MR were correlated with findings on CT as well as with cerebral...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198811000-00037
更新日期:1988-11-01 00:00:00
abstract:OBJECTIVE:To determine the natural history of fluid collections that occur within the osseous tunnel after autologous hamstring repair of the anterior cruciate ligament (ACL) and to correlate with clinical outcomes. METHODS:Twenty-two patients were imaged within 1 year after autologous hamstring repair of the ACL and ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200207000-00025
更新日期:2002-07-01 00:00:00