The Recent Infection Testing Algorithm (RITA) in clinical practice: a survey of HIV clinicians in England and Northern Ireland.

abstract：OBJECTIVES:To determine whether mutations conferring drug resistance are detectable after zidovudine monotherapy (ZDVm) in pregnancy, using both standard genotyping and more sensitive cloning assays. METHODS:Post-delivery samples from women meeting the British HIV Association guidelines criteria for the use of ZDVm in...

journal_title：HIV medicine

authors： Read P,Costelloe S,Mullen J,O'Shea S,Lyons F,Hay P,Welch J,Larbalestier N,Taylor G,de Ruiter A

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to assess the currently available evidence concerning the management of dyslipidaemias in HIV-infected individuals treated with antiretroviral therapy. METHODS:Randomized trials, published within the 5 years preceding 5 October 2005, were identified in PubMed Medline, Embase, and Th...

journal_title：HIV medicine

authors： McGoldrick C,Leen CL

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVES:Human leukocyte antigen (HLA)-B(*)5701 is strongly associated with developing a hypersensitivity reaction to abacavir (ABC) in White and Hispanic subjects. Across the UK, limited data exist on HLA-B(*)5701 prevalence in HIV-1-infected subjects. We determined HLA-B(*)5701 prevalence in the general HIV-1-infec...

journal_title：HIV medicine

authors： Orkin C,Sadiq ST,Rice L,Jackson F,UK EPI team.

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVES:Three-drug nonoccupational post-exposure prophylaxis (NPEP) typically includes co-formulated emtricitabine-tenofovir (FTC-TDF) and a protease inhibitor. However, protease inhibitors can cause significant toxicities, can interact with prescribed and illicit drugs, and work late in the viral cycle. Agents that...

journal_title：HIV medicine

authors： McAllister J,Read P,McNulty A,Tong WW,Ingersoll A,Carr A

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:Different experimental approaches have shown that, despite plasma viral loads under the threshold of detection, HIV-1 frequently continues to replicate in patients receiving potent antiretroviral therapy. However, whether this low-grade viral replication is sufficient for the generation of new major quasispe...

journal_title：HIV medicine

authors： Birk M,Aleman S,Visco-Comandini U,Sönnerborg A

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVES:Rapid HIV testing (RHT) is well established in many countries, but it is new in Australia since a policy change in 2011. We assessed service provider acceptability of RHT before and after its implementation in four Sydney public sexual health clinics. METHODS:Service providers were surveyed immediately afte...

journal_title：HIV medicine

authors： Conway DP,Guy R,McNulty A,Couldwell DL,Davies SC,Smith DE,Keen P,Cunningham P,Holt M,Sydney Rapid HIV Test Study.

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:To study the impact of effective highly active antiretroviral therapy (HAART) on the preservation of long-term CD4 memory cells induced by vaccines in HIV-1-infected patients. METHODS:Thirty HIV-1-positive patients on HAART with undetectable viral load were randomized into three groups: 10 received HIV-1 rgp...

journal_title：HIV medicine

authors： Hejdeman B,Leandersson AC,Fredriksson EL,Sandström E,Wahren B,Bratt G

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVES:The acquisition of adequate vaccine-induced humoral immunity is especially important in HIV-infected individuals, who are at increased risk of infections. The aim of the study was to assess the safety of administering a complete vaccination programme to successfully treated HIV-infected adults and to evaluat...

journal_title：HIV medicine

authors： González R,Castro P,García F,Plana M,Bayas JM,Lafuente S,Serrano B,Mora B,Argelich R,Gatell JM,Vilella A

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVES:The Joint United Nations Programme on HIV/AIDS (UNAIDS)/World Health Organization (WHO) 90-90-90 goals propose that 90% of all people living with HIV should know their HIV status, 90% of those diagnosed should receive antiretroviral therapy (ART), and 90% of those should have durable viral suppression. We ha...

journal_title：HIV medicine

authors： Gisslén M,Svedhem V,Lindborg L,Flamholc L,Norrgren H,Wendahl S,Axelsson M,Sönnerborg A

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to identify and describe the characteristics of persons born in the UK who acquire HIV infection abroad. METHODS:Analyses using case reports and follow-up data from the national HIV database held at the Health Protection Agency were performed. RESULTS:Fifteen per cent (2066 of 13 8...

journal_title：HIV medicine

authors： Rice B,Gilbart VL,Lawrence J,Smith R,Kall M,Delpech V

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:As a proactive diagnosis of diabetes mellitus (DM) may prevent the onset of severe complications, we used an oral glucose tolerance test (OGTT) to check for impaired glucose tolerance (IGT) and DM in patients with long-standing HIV infection and long durations of exposure to antiretroviral drugs with normal f...

journal_title：HIV medicine

authors： Gianotti N,Visco F,Galli L,Barda B,Piatti P,Salpietro S,Bigoloni A,Vinci C,Nozza S,Gallotta G,Lazzarin A,Castagna A

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to determine the factors that may contribute to decreases in bone mineral density (BMD) in patients with AIDS. METHODS:This was a prospective, non-randomized study. Dual X-ray absorptiometry (DXA) was used to determine the BMD of the lumbar spine, femoral neck and distal radius in t...

journal_title：HIV medicine

authors： Rivas P,Górgolas M,García-Delgado R,Díaz-Curiel M,Goyenechea A,Fernández-Guerrero ML

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVES:Hepatitis C virus (HCV) has emerged as an important health problem in the era of effective HIV treatment. However, very few data exist on the health status and disease burden of HIV/HCV-coinfected Canadians. METHODS:HIV/HCV-coinfected patients were enrolled prospectively in a multicentre cohort from 16 cent...

journal_title：HIV medicine

authors： Klein MB,Rollet KC,Saeed S,Cox J,Potter M,Cohen J,Conway B,Cooper C,Côté P,Gill J,Haase D,Haider S,Hull M,Moodie E,Montaner J,Pick N,Rachlis A,Rouleau D,Sandre R,Tyndall M,Walmsley S,Canadian HIV-HCV Cohort Inve

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:Effective HIV therapy reflects suppression of plasma HIV RNA levels below assay detection thresholds, although lower levels of "residual viraemia" have also been demonstrated over extended periods of effective antiretroviral treatment. Here we examine the determinants of HIV RNA suppression below the standar...

journal_title：HIV medicine

authors： McKinnon E,Castley A,Payne L,Pummer S,Nolan D

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:ODIN (once-daily darunavir in treatment-experienced patients) was a 48-week, phase III, randomized, open-label trial comparing once-daily (qd) darunavir/ritonavir (DRV/r) 800/100 mg with twice-daily (bid) DRV/r 600/100 mg, both with an optimized background regimen [OBR; at least two nucleoside reverse transc...

journal_title：HIV medicine

authors： Sension M,Cahn P,Domingo P,Hodder S,Opsomer M,Lathouwers E,Van de Casteele T,Tomaka F

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVES:An article by the Swiss AIDS Commission states that patients with stably suppressed viraemia [i.e. several successive HIV-1 RNA plasma concentrations (viral loads, VL) below the limits of detection during 6 months or more of highly active antiretroviral therapy (HAART)] are unlikely to be infectious. Questio...

journal_title：HIV medicine

authors： Combescure C,Vallier N,Ledergerber B,Cavassini M,Furrer H,Rauch A,Battegay M,Bernasconi E,Vernazza P,Hirschel B,Swiss HIV Cohort Study.

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVES:Antiretroviral therapy during pregnancy is recommended to reduce the risk of mother-to-child transmission of HIV and for maternal care management. Physiological changes during pregnancy can affect pharmacokinetics, potentially altering pharmacological activity. We therefore evaluated the pharmacokinetics of ...

journal_title：HIV medicine

authors： Zorrilla CD,Wright R,Osiyemi OO,Yasin S,Baugh B,Brown K,Coate B,Verboven P,Mrus J,Falcon R,Kakuda TN

更新日期：2014-01-01 00:00:00

abstract：:We report the case of an asthmatic man with HIV infection who was initially diagnosed with HIV treatment-associated lipodystrophy. Further investigations showed he had Cushing's syndrome secondary to 1600 microg of budesonide dry powder inhaler. Cushing's syndrome has not been reported previously on this normal dose o...

journal_title：HIV medicine

authors： le Roux CW,Beckles MA,Besser GM,Pinching AJ,Davison AG

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVES:We describe the management of a cohort of eight HIV-positive patients on antiretroviral medication with evidence of pancreatic insufficiency consisting of chronic diarrhoea and a low faecal elastase measurement. PATIENTS AND METHODS:Twenty-two patients with chronic diarrhoea for whom a faecal elastase measu...

journal_title：HIV medicine

authors： Price DA,Schmid ML,Ong EL,Adjukeiwicz KM,Peaston B,Snow MH

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:More than 10 years after the introduction of combination antiretroviral therapy (cART), we examined the trend in the proportion of deaths caused by end-stage liver disease (ESLD) in HIV-infected adults in France between 1995 and 2005. DESIGN AND METHODS:In 2005, 34 departments prospectively recorded all dea...

journal_title：HIV medicine

authors： Rosenthal E,Salmon-Céron D,Lewden C,Bouteloup V,Pialoux G,Bonnet F,Karmochkine M,May T,François M,Burty C,Jougla E,Costagliola D,Morlat P,Chêne G,Cacoub P,Mortavic\/Mortalité 2005 Study Group.

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVES:The nonnucleoside reverse transcriptase inhibitor (NNRTI) efavirenz undergoes phase I metabolism by the cytochrome P450 enzyme, CYP2B6. Previous studies outside of the United Kingdom have shown associations between the CYP2B6 polymorphism G516T and increased toxicity. This study aimed to develop a CYP2B6 G51...

journal_title：HIV medicine

authors： Powers V,Ward J,Gompels M

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to investigate HIV testing practice among female sex workers (FSWs) and men who have sex with men (MSM) in Tbilisi, Georgia and to identify determinants of never testing behaviour among MSM. METHODS:Data obtained in two rounds of bio-behavioural surveys among FSWs (2006 and 2009) an...

journal_title：HIV medicine

authors： Tsereteli N,Chikovani I,Chkhaidze N,Goguadze K,Shengelia N,Rukhadze N

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to investigate the association of adiposity with longitudinal kidney function change in 544 HIV-infected persons in the Study of Fat Redistribution and Metabolic Change in HIV infection (FRAM) cohort over 5 years of follow-up. METHODS:The regional distribution of muscle and adipose ...

journal_title：HIV medicine

authors： Malkina A,Scherzer R,Shlipak MG,Bacchetti P,Tien PC,Grunfeld C,Kosmiski L,Peralta CA

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:To determine whether HIV-infected mothers knew the HIV status of their children, enabling the offer of targeted testing of children at risk. METHODS:All HIV-positive women attending the genitourinary medicine clinic at a district general hospital in the United Kingdom were asked whether they had children an...

journal_title：HIV medicine

authors： Eisenhut M,Sharma V,Kawsar M,Balachandran T

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:To establish the prevalence, severity and factors associated with the HIV lipodystrophy syndrome. METHODS:Cross-sectional study of lipodystrophy conducted in high HIV caseload primary care sites and HIV outpatient clinics. A subset of patients was examined using dual energy X-ray absorptiometry (DEXA) and si...

journal_title：HIV medicine

authors： Miller J,Carr A,Emery S,Law M,Mallal S,Baker D,Smith D,Kaldor J,Cooper DA

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to describe the prevalence of and examine the factors associated with immunosuppression (CD4 < 200 cells/microL) among HIV-infected patients attending two large inner London treatment centres. METHODS:Patients attending for care who had a CD4 count < 200 cells/microL during a 6-mont...

journal_title：HIV medicine

authors： Harte D,Dosekun O,Sethi G,Chadborn T,de Ruiter A,Copas A,Edwards SG,Miller RF

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to seek correlates of immune protection in HIV infection. We sought to elucidate the association between the presence of human leucocyte antigen (HLA) alleles, as well as killer immunoglobulin receptor (KIR) genotypes, and the susceptibility to HIV infection in a Spanish cohor...

journal_title：HIV medicine

authors： Rallón N,Restrepo C,Vicario JL,Del Romero J,Rodríguez C,García-Samaniego J,García M,Cabello A,Górgolas M,Benito JM

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:For the last 10 years there has been an epidemic of hepatitis C virus (HCV) infection in men who have sex with men (MSM) in Europe, North America and Australia. The majority of those infected are also HIV-positive and it is unclear to what extent HIV-negative MSM are also at increased risk of infection with ...

journal_title：HIV medicine

authors： Price H,Gilson R,Mercey D,Copas A,Parry J,Nardone A,Johnson A,Hart G

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to explore the awareness of rectal microbicides, the use of pre-exposure prophylaxis (PREP) and the willingness to participate in biomedical HIV prevention trials in a cohort of HIV-negative gay men. METHODS:In a community-based cohort study, HIV-negative homosexually active men in ...

journal_title：HIV medicine

authors： Poynten IM,Jin F,Prestage GP,Kaldor JM,Imrie J,Grulich AE

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:People living with HIV infection are at increased risk for developing cardiovascular disease (CVD). Safe and effective interventions for lowering CVD risk in HIV infection are high priorities. We conducted a prospective, randomized, controlled study to evaluate whether a yoga lifestyle intervention improves C...

journal_title：HIV medicine

authors： Cade WT,Reeds DN,Mondy KE,Overton ET,Grassino J,Tucker S,Bopp C,Laciny E,Hubert S,Lassa-Claxton S,Yarasheski KE

更新日期：2010-07-01 00:00:00