Penicillic acid production in submerged culture.

Abstract:

:Twenty known penicillic acid (PA)-producing Aspergillus and Penicillium cultures were grown under various conditions in shaken flasks to determine the highest yielding strains and their requirements for maximum toxin production. Abilities of the cultures to utilize eight different carbon sources in Raulin-Thom medium for mycotoxin synthesis were determined at four different incubation temperatures: 15, 20, 25, and 28 degrees C. Of the 20 cultures, P. cyclopium NRRL 1888 was superior, yielding up to 4 mg of PG per ml, with mannitol as the carbon source and 25 degrees C as the incubation temperature. Fifteen of the cultures elaborated lesser amounts of PA, whereas four strains yielded none under the test conditions. Whey from the manufacture of cottage cheese by the cultured process was also a satisfactory medium for PA production. In whey medium, yields up to 3 mg/ml were obtained with P. cyclopium NRRL 1888.

journal_name

Appl Environ Microbiol

authors

Lindenfelser LA,Ciegler A

doi

10.1128/AEM.34.5.553-556.1977

subject

Has Abstract

pub_date

1977-11-01 00:00:00

pages

553-6

issue

5

eissn

0099-2240

issn

1098-5336

journal_volume

34

pub_type

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