Maternal use of antibiotics and the risk of orofacial clefts: a nationwide cohort study.

abstract：PURPOSE:Innovative methods are needed to assess risks related to treatment for common medical conditions, where therapy is usually patient-directed or over-the-counter (OTC), and where tolerability, i.e. patient experienced events, may affect patterns of use. A large-scale, blinded, randomised trial was conducted to co...

journal_title：Pharmacoepidemiology and drug safety

authors： Van Ganse E,Jones JK,Moore N,Parc JM,Wall R,Schneid H

更新日期：2005-04-01 00:00:00

abstract：PURPOSE:We aimed to describe time-trends in the use of NOACs among a group of ambulatory patients with nonvalvular atrial fibrillation (NVAF) in Colombia and to describe treatment patterns and user characteristics. METHODS:Using the Audifarma S.A administrative healthcare database in Colombia, we identified 10 528 pat...

journal_title：Pharmacoepidemiology and drug safety

authors： Machado-Alba JE,Gaviria-Mendoza A,Machado-Duque ME,Tovar-Yepes C,Ruigómez A,García Rodríguez LA

更新日期：2020-10-15 00:00:00

abstract：INTRODUCTION:Cancer-related fatigue (CRF) has been suggested to be associated with the occurrence of chemotherapy-induced nausea and vomiting (CINV). This study aims to evaluate the potential of CRF in predicting the occurrence of CINV. METHOD:This is a prospective, observational study. Recruited patients received mod...

journal_title：Pharmacoepidemiology and drug safety

authors： Poon KS,Un MK,Low XH,Cheung YT,Yap KY,Chan A

更新日期：2013-12-01 00:00:00

abstract：:Adverse drug reaction surveillance conducted by the US Federal Food and Drug Administration (FDA) is important for detecting new safety information about pharmaceuticals. FDA has sought to stimulate reporting of reactions by practitioners and manufacturers. Over the five years from 1989 to 1993, reporting more than do...

journal_title：Pharmacoepidemiology and drug safety

authors： Faich GA

更新日期：1996-11-01 00:00:00

abstract：:Analysing duration of treatment episodes has become a standard task in many pharmacoepidemiological studies. However, such analyses are often carried out in a rather simplistic manner and more subtle issues are often ignored. In this paper, methods of analysing duration treatment episodes beyond simple analyses allowi...

journal_title：Pharmacoepidemiology and drug safety

authors： Gichangi A,Andersen M,Kragstrup J,Vach W

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVES:This study quantifies the incidence of liver enzyme abnormalities in the general population of central Massachusetts. METHODS:Computerized data files from a health maintenance organization were used to ascertain potential subjects during the study period of 1 July 1992-30 June 1993. Medical records and labo...

journal_title：Pharmacoepidemiology and drug safety

authors： Duh MS,Walker AM,Kronlund KH Jr

更新日期：1999-07-01 00:00:00

abstract：PURPOSE:Determining the nature of the relationship between cumulative duration of exposure to an agent and the hazard of an adverse outcome is an important issue in environmental and occupational epidemiology, public health and clinical medicine. The Cox proportional hazards regression model can incorporate time-depend...

journal_title：Pharmacoepidemiology and drug safety

authors： Austin PC,Park-Wyllie LY,Juurlink DN

更新日期：2014-08-01 00:00:00

abstract：PURPOSE:Risk assessment for natural health products (NHPs) may not be evaluated similarly to therapeutic products by Health Canada in terms of notification of harms to consumers and health professionals. In this descriptive study, we evaluated risk communications (RCs) issued by Health Canada for NHPs and for therapeut...

journal_title：Pharmacoepidemiology and drug safety

authors： Bateman J,Charrois TL,Gardiner P,Vohra S

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:To determine the effectiveness of quality circles on prescribing patterns of primary care physicians in Germany and to explore the influence of specific factors on changes. METHODS:Three large non-randomised comparative studies were performed in primary care in Germany, with baseline measurements in 2001 and f...

journal_title：Pharmacoepidemiology and drug safety

authors： Wensing M,Broge B,Riens B,Kaufmann-Kolle P,Akkermans R,Grol R,Szecsenyi J

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:As covariates are not always adequately balanced after propensity score matching and double- adjustment can be used to remove residual confounding, we compared the performance of several double-robust estimators in different scenarios. METHODS:We conducted a series of Monte Carlo simulations on virtual obser...

journal_title：Pharmacoepidemiology and drug safety

authors： Nguyen TL,Collins GS,Spence J,Devereaux PJ,Daurès JP,Landais P,Le Manach Y

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:To assess the prevalence of adverse drug reactions (ADRs) occurring in patients with Alzheimer's disease (AD) or other dementia in France. METHODS:A cross-sectional multicentre study was conducted by the French network of the 31 regional pharmacovigilance centres on a given day. The subjects were selected by r...

journal_title：Pharmacoepidemiology and drug safety

authors： Laroche ML,Perault-Pochat MC,Ingrand I,Merle L,Kreft-Jais C,Castot-Villepelet A,Durrieu G,Gras V,Guy C,Jean-Pastor MJ,Jonville-Béra AP,Merlet-Chicoine I,Miremont-Salamé G,Nourhashemi F,Charmes JP,French Centres of Pharmacov

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:Although sales of prescribed and over-the-counter (OTC) medication are rising, little is known about individual drug intake. This study was aimed to obtain complementary information about drug intake. METHOD:Information on drug utilization was obtained in a female cohort for five different time points (TP): 36...

journal_title：Pharmacoepidemiology and drug safety

authors： Hoeke H,Roeder S,Bertsche T,Borte M,von Bergen M,Wissenbach DK

更新日期：2016-04-01 00:00:00

abstract：:The ability to manage risk depends critically on an understanding of the degree to which a known risk is balanced by the probability of a clinical benefit. Despite the massive emphasis on risk and risk management in the past few years and the long-term focus on defining benefit in the regulatory system, considerable u...

journal_title：Pharmacoepidemiology and drug safety

authors： Califf RM,CERTs Benefit Assessment Workshop Participants.

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:The aim of the present study was to determine whether community pharmacists recommend appropriate medications and give valid information to pregnant women. METHODS:A total of 163 community pharmacists randomly selected in the Midi-Pyrénées area were interviewed by means of an open questionnaire. Ten scenarios ...

journal_title：Pharmacoepidemiology and drug safety

authors： Damase-Michel C,Vié C,Lacroix I,Lapeyre-Mestre M,Montastruc JL

更新日期：2004-10-01 00:00:00

abstract：PURPOSE:Chronic kidney disease (CKD) is a prevalent and important outcome and covariate in pharmacoepidemiology. The Health Improvement Network (THIN) in the UK represents a unique resource for population-based studies of CKD. We compiled a valid list of Read codes to identify subjects with moderate to advanced CKD. M...

journal_title：Pharmacoepidemiology and drug safety

authors： Denburg MR,Haynes K,Shults J,Lewis JD,Leonard MB

更新日期：2011-11-01 00:00:00

abstract：UNLABELLED:Computerized hospital databases are used for clinical and economic research. In France, the hospital administrative database, Programme de médicalisation des systèmes d'information (PMSI), could be an interesting means for identifying cases of abuse and dependence in hospitals. PURPOSE:To assess the capabil...

journal_title：Pharmacoepidemiology and drug safety

authors： Daveluy A,Miremont-Salamé G,Kostrzewa A,Couret A,Lacoin L,Lecomte C,Moore N,Gilleron V,Haramburu F

更新日期：2012-12-01 00:00:00

abstract：PURPOSE:Three recent observational studies reported that the risk of fatal overdose is greater with venlafaxine than SSRI use. It is not clear whether patient factors could account for this finding. We evaluated whether risk factors for suicide are more prevalent among patients prescribed venlafaxine than patients pres...

journal_title：Pharmacoepidemiology and drug safety

authors： Mines D,Hill D,Yu H,Novelli L

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to generate data regarding the drug utilization pattern in pediatric population of our tertiary care hospital so that we could generate an essential medicine list (EML). BACKGROUND:Drug therapy accounts for a major portion of expenditure toward health care. Reduction in health ...

journal_title：Pharmacoepidemiology and drug safety

authors： Singh I,Mittal R,Shafiq N,Bharati B,Nigah RK,Pandhi P,Chaudhary RR,Malhotra S

更新日期：2010-04-01 00:00:00

abstract：PURPOSE:To assess the feasibility of using Clinical Practice Research Datalink (CPRD) data for identifying populations of patients with chronic obstructive pulmonary disease (COPD) eligible for a hypothetical pragmatic trial. METHODS:A retrospective multidatabase cohort study using CPRD primary care and linked seconda...

journal_title：Pharmacoepidemiology and drug safety

authors： Requena G,Wolf A,Williams R,Dedman D,Quint JK,Murray-Thomas T,Pimenta JM

更新日期：2020-12-27 00:00:00

abstract：OBJECTIVE:To assess the extent, characteristics and determinants of benzodiazepine prescription in outpatient Primary Health Care. METHODS:A clinical audit of a stratified random sample of Primary Health Care Centres in the seven islands and 1.6 million inhabitants region of 'Canarias' in Spain was carried out. From t...

journal_title：Pharmacoepidemiology and drug safety

authors： de las Cuevas C,Sanz E,de la Fuente JA,Cabrera C,Mateos A

更新日期：1999-05-01 00:00:00

abstract：PURPOSE:Community Pharmacists both have an important responsibility in monitoring the ongoing safety of medicines and are widely accessible to do it. This study aims to investigate the knowledge, perceptions and practice of Pharmacovigilance amongst community pharmacists in Lagos State, South West Nigeria METHODS:A cr...

journal_title：Pharmacoepidemiology and drug safety

authors： Oreagba IA,Ogunleye OJ,Olayemi SO

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:To identify and quantify risk factors associated with preterm birth, stratified by gestational age at birth. METHODS:Three case-control analyses were done. Controls were pregnancies of > or =37 weeks of gestational age at birth. Cases were defined as: <28, 28-32, 33- <37 weeks of gestational age at birth respe...

journal_title：Pharmacoepidemiology and drug safety

authors： Ofori BD,Le Tiec M,Bérard A

更新日期：2008-06-01 00:00:00

abstract：PURPOSE:Although a series of serious adverse events have continually raised concerns about the potential toxicity of traditional Chinese medicine injections (TCM injections), studies on this subject are still sparse. We conducted a descriptive analysis of a spontaneous reporting system in China to describe the safety p...

journal_title：Pharmacoepidemiology and drug safety

authors： Li H,Deng J,Deng L,Ren X,Xia J

更新日期：2019-07-01 00:00:00

abstract：PURPOSE:The abuse and nonmedical use of prescription opioids and its subsequent consequences are an important public health concern. This phenomenon has paralleled the increase in the therapeutic use of opioids for pain management. There is thus a need to measure prescription opioid abuse to understand trends over time...

journal_title：Pharmacoepidemiology and drug safety

authors： Secora AM,Dormitzer CM,Staffa JA,Dal Pan GJ

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:To determine the prevalence of purchase of prescribed antihypertensive and/or serum lipid-reducing pharmaceutical preparations among different age groups, from the age of 45, in the Swedish population. Further, to calculate the percentage of the population, from the age of 60, who purchased these pharmaceutical...

journal_title：Pharmacoepidemiology and drug safety

authors： Silwer L,Lundborg CS,Petzold M

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to examine epidemiologic characteristics of Adverse Drug Events (ADEs) among children and adolescents presenting to an Emergency Department (ED) in Newfoundland and Labrador (NL), Canada. MATERIALS AND METHODS:This study was conducted in three phases and included an ED chart review...

journal_title：Pharmacoepidemiology and drug safety

authors： Sikdar KC,Alaghehbandan R,Macdonald D,Barrett B,Collins KD,Gadag V

更新日期：2010-02-01 00:00:00

abstract：:The General Practice Research Database (GPRD) is the world's largest computerized database of anonymized longitudinal patient records from general practice and is a unique public health research tool. Several issues have threatened the viability of the database in recent years; in April 1999 responsibility for its man...

journal_title：Pharmacoepidemiology and drug safety

authors： Wood L,Coulson R

更新日期：2001-08-01 00:00:00

abstract：PURPOSE:Determine the relative risk of cancer users of commonly prescribed antihypertensive drugs with a focus on documenting risk in long-term users (>7.5 years). METHODS:We conducted a nested case-control study using the Saskatchewan Health databases. Cancer risks in users of beta-blockers, calcium channel blockers ...

journal_title：Pharmacoepidemiology and drug safety

authors： Assimes TL,Elstein E,Langleben A,Suissa S

更新日期：2008-11-01 00:00:00

abstract：PURPOSE:To assess the validity of dispensed prescription to classify exposure to medications used episodically during pregnancy, and to explore individual trajectories of episodic medication use across pregnancy, using triptans for migraine as the motivating example. METHODS:We compared self-reported triptan use durin...

journal_title：Pharmacoepidemiology and drug safety

authors： Harris GE,Wood M,Nordeng H

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:To identify the relevant prescribing quality domains of type 2 diabetes mellitus care as a basis for the selection of a minimal set of prescribing quality indicators from a set of previously validated indicators. METHODS:We used the principal factor analysis to identify the underlying dimensions or domains o...

journal_title：Pharmacoepidemiology and drug safety

authors： Martirosyan L,Haaijer-Ruskamp FM,Braspenning J,Denig P

更新日期：2012-10-01 00:00:00