Induction therapy for lung cancer: sailing across the pillars of Hercules.

Abstract:

:In spite of numerous clinical trials, the jury is still out on the value of induction therapy for locally advanced lung cancer. We elected to address this topic from the multifaceted views of the clinicians often involved in lung cancer management and according the most recent views on locally advanced NSCLC. The concept of a prognostic stratification of N2 disease subsets, especially single vs multiple zone, has been introduced and this may lead to a new interpretation of locally advanced NSCLC. Ten crucial issues were identified that may have an impact on the approach to patients with locally advanced lung cancer in everyday practice.

journal_name

Thorac Surg Clin

journal_title

Thoracic surgery clinics

authors

Rocco G,Morabito A,Muto P

doi

10.1016/j.thorsurg.2011.08.010

subject

Has Abstract

pub_date

2012-02-01 00:00:00

pages

67-75, vi

issue

1

eissn

1547-4127

issn

1558-5069

pii

S1547-4127(11)00098-3

journal_volume

22

pub_type

杂志文章,评审
  • Traumatic diaphragmatic injuries.

    abstract::Although numerous articles have been written over the past two decades with regard to the treatment of traumatic diaphragmatic hernia, little has actually changed during that time. The ability to make the diagnosis has somewhat improved because of the technologic advances in CT; however, it remains true that the best ...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2007.03.006

    authors: Scharff JR,Naunheim KS

    更新日期:2007-02-01 00:00:00

  • Correlative anatomy for the esophagus.

    abstract::Because the esophagus is a tubular muscular structure only partially filled with air and surrounded by major structures (vessels, lungs, and heart), its radiologic evaluation cannot be performed solely by conventional chest radiograph or barium studies. The emergence of newer techniques has had a dramatic effect on th...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章

    doi:10.1016/j.thorsurg.2010.12.007

    authors: Ugalde PA,Pereira ST,Araujo C

    更新日期:2011-05-01 00:00:00

  • Surgical approaches and techniques in the management of severe hyperhidrosis.

    abstract::Thoracoscopy has afforded a huge advance for upper thoracic sympathetic procedures compared with prior open procedures. Different clinical syndromes of hyperhidrosis exist and require different forms of treatment. The classic severe palmoplantar pattern of hyperhidrosis will not respond effectively in the long term to...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2008.01.005

    authors: Baumgartner FJ

    更新日期:2008-05-01 00:00:00

  • Video-assisted thoracoscopic surgery lobectomy for stage I lung cancer.

    abstract::The literature shows that, in the hands of experienced thoracoscopic surgeons, VL is a safe operation that offers patients at least comparable complication and survival rates compared with lobectomy by thoracotomy. VL can be performed safely with proven advantages over conventional thoracotomy for lobectomy: smaller i...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2007.03.019

    authors: Mahtabifard A,DeArmond DT,Fuller CB,McKenna RJ Jr

    更新日期:2007-05-01 00:00:00

  • Nonintubated Video-Assisted Thoracic Surgery for the Management of Primary and Secondary Spontaneous Pneumothorax.

    abstract::Nonintubated video-assisted thoracoscopic surgery for the treatment of primary and secondary pneumothorax was first reported in 1997 by Nezu. However, studies on this technique are few. Research in the past 20 years has focused on the perioperative outcomes, including the surgical duration, length of hospital stay, an...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2019.08.001

    authors: Chen PH,Hung WT,Chen JS

    更新日期:2020-02-01 00:00:00

  • Endoscopic antireflux therapy: the Stretta procedure.

    abstract::The Stretta procedure is safe and effective for the treatment of GERD. There are well-documented clinical trial data supporting its use, including a randomized sham-controlled study, single- and multi-center prospective trials, and community practice reports. The complication rate is within the acceptable range for th...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2005.03.006

    authors: Yeh RW,Triadafilopoulos G

    更新日期:2005-08-01 00:00:00

  • Risk acceptance and risk aversion: patients' perspectives on lung surgery.

    abstract::Patients express risk aversion toward surgery, particularly if surgery can lead to lifelong debility and loss of independence. When faced with a guarantee of progressive lung cancer and no alternatives for cure, however, patients are willing to take extremely high risks of postoperative complications and surgery-relat...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章

    doi:10.1016/S1547-4127(04)00016-7

    authors: Cykert S

    更新日期:2004-08-01 00:00:00

  • Update on donor assessment, resuscitation, and acceptance criteria, including novel techniques--non-heart-beating donor lung retrieval and ex vivo donor lung perfusion.

    abstract::The shortage of adequate organ donors remains a great challenge in clinical lung transplantation. With increasing experience in the medical management and surgical technique of lung transplantation, gradual expansion of the criteria for lung donor selection has occurred with beneficial effects on the donor pool. Inter...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2009.02.006

    authors: Yeung JC,Cypel M,Waddell TK,van Raemdonck D,Keshavjee S

    更新日期:2009-05-01 00:00:00

  • Long-term outcomes of thoracoscopic lobectomy.

    abstract::Thoracoscopic lobectomy is emerging as the procedure of choice for patients with early stage non-small cell lung cancer, based on advantages in quality of life as well as long-term outcomes. In addition, thoracoscopic lobectomy has been demonstrated to be safe and effective for selected patients with locally advanced ...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2008.04.002

    authors: D'Amico TA

    更新日期:2008-08-01 00:00:00

  • The Staging of Malignant Pleural Mesothelioma.

    abstract::Staging of malignant pleural mesothelioma has been challenging because of a paucity of cases and poor survival. At least 5 staging systems were proposed before 1990 until the first consensus system was published in 1995. This system used tumor, node, metastasis designations and borrowed heavily from parenchymal lung c...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2020.07.001

    authors: Euhus CJ,Ripley RT

    更新日期:2020-11-01 00:00:00

  • Cervical videomediastinoscopy.

    abstract::Cervical mediastinoscopy is a frequently used technique to assess the mediastinum, in particular the mediastinal lymph nodes in patients presenting with non-small cell lung cancer (NSCLC). The senior author of this article is credited for developing in 1989 the concept of what is now called videomediastinoscopy. The i...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2010.01.006

    authors: Lerut T,De Leyn P,Coosemans W,Decaluwé H,Decker G,Nafteux P,Van Raemdonck D

    更新日期:2010-05-01 00:00:00

  • Management of Malignant Lung Entrapment, the Oncothorax.

    abstract::Pleural metastasis is a common occurrence in up to 30% of patients with metastatic cancer. When lung entrapment and loculation of fluid occur, treatment is more difficult and we have named this condition "oncothorax." The malignant adhesions that entrap the lung in an oncothorax are not typically amenable to surgical ...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2017.08.009

    authors: Petrov R,Bakhos C,Abbas AE

    更新日期:2018-02-01 00:00:00

  • Videothoracoscopic approach to the spine in idiopathic scoliosis.

    abstract::Surgical treatment of idiopathic scoliosis has classically included posterior, anterior, or combined open surgical techniques. In recent years, a videothoracoscopic approach to the spine has been increasingly employed either in combination with the posterior open approach or as a stand-alone treatment including anteri...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2010.01.004

    authors: Pompeo E,Mancini F,Ippolito E,Mineo TC

    更新日期:2010-05-01 00:00:00

  • Anatomy of the trachea, carina, and bronchi.

    abstract::This article summarizes the pertinent points of tracheal and bronchial anatomy, including the relationships to surrounding structures. Tracheal and bronchial anatomy is essential knowledge for the thoracic surgeon, and an understanding of the anatomic relationships surrounding the airway is crucial to the safe perform...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2006.12.006

    authors: Minnich DJ,Mathisen DJ

    更新日期:2007-11-01 00:00:00

  • Vertebral body resection.

    abstract::Vertebral body resection for locally advanced lung cancer can be performed with acceptable morbidity and mortality rates, and with improved long-term survival, when combined with chemotherapy and radiation. A consensus has not been reached on either the optimal extent of vertebral resection or the optimal treatment re...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/S1547-4127(04)00009-X

    authors: Martin LW,Walsh GL

    更新日期:2004-05-01 00:00:00

  • The molecular biology of pulmonary metastasis.

    abstract::Curing cancer requires the treatment of metastatic disease. Whether this is a patient with advanced disease and clinically apparent metastases, or if the patient with localized disease is at risk for development of dissemination, failure to control metastasis will result in a poor outcome. Here, we have presented a mo...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2005.12.003

    authors: Krishnan K,Khanna C,Helman LJ

    更新日期:2006-05-01 00:00:00

  • Staged lung volume reduction surgery--rationale and experience.

    abstract::The current convention is for bilateral one-stage lung volume reduction surgery. Unilateral surgery results in a symptomatic improvement in most patients. A staged approach to the second lung may reduce the risk of surgery and lead to a slower decline in physiologic improvement. The timing of the second operation can ...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2009.02.001

    authors: Waller D,Oey I

    更新日期:2009-05-01 00:00:00

  • Endoluminal Therapies for Esophageal Perforations and Leaks.

    abstract::Esophageal perforation has historically been a devastating condition resulting in high morbidity and mortality. The use of endoluminal therapies to treat esophageal leaks and perforations has grown exponentially over the last decade and offers many advantages over traditional surgical intervention in the appropriate c...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2018.07.002

    authors: Watkins JR,Farivar AS

    更新日期:2018-11-01 00:00:00

  • Open, Minimally Invasive, and Robotic Approaches for Esophagectomy: What Is the Approach Algorithm?

    abstract::Esophageal cancer requires a multimodality treatment approach, with surgical resection a key component in many cases. When it comes to esophagectomy, several approaches and techniques exist, including transhiatal versus transthoracic and open versus minimally invasive. Each approach has its associated risks and advant...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2020.04.010

    authors: Witek TD,Melvin TJ,Luketich JD,Sarkaria IS

    更新日期:2020-08-01 00:00:00

  • Video-assisted thoracoscopic (VATS) lobectomy after induction therapy.

    abstract::Concerns regarding the sequelae of neoadjuvant chemotherapy or chemoradiotherapy on the pleural space and tissue planes had previously deterred the application of video-assisted thoracoscopic (VATS) lobectomy for patients who underwent neoadjuvant therapy. As experience with VATS has increased, however, its applicatio...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2014.07.013

    authors: Mollberg NM,Mulligan MS

    更新日期:2014-11-01 00:00:00

  • Robot-assisted lung anatomic segmentectomy: technical aspects.

    abstract::Anatomic lung segmentectomy is a possible alternative to lobectomy for small (<2 cm) primary lung cancers. Interest in anatomic lung segmentectomy has increased further after the adoption of high-resolution computed tomography and the implementation of lung cancer screening studies, which are increasing the detection ...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2014.02.008

    authors: Pardolesi A,Veronesi G

    更新日期:2014-05-01 00:00:00

  • Tracheobronchomalacia and Expiratory Collapse of Central Airways.

    abstract::Tracheobronchomalacia is an uncommon acquired disorder of the central airways. Common symptoms include dyspnea, constant coughing, inability to raise secretions, and recurrent respiratory infections. Evaluation includes an inspiratory-expiratory chest CT (dynamic CT), an awake functional bronchoscopy, and pulmonary fu...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2018.01.006

    authors: Wright CD

    更新日期:2018-05-01 00:00:00

  • Fast-tracking: eliminating roadblocks to successful early discharge.

    abstract::With continually increasing health care costs and limited medical resources, there has been increasing focus on shortening hospital stays. Many medical and nonmedical reasons can lead to a delay in hospital discharge after thoracic surgery despite technically successful procedures; common obstacles include inadequate ...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章

    doi:10.1016/j.thorsurg.2005.01.007

    authors: Lin J,Iannettoni MD

    更新日期:2005-05-01 00:00:00

  • Complications of pulmonary resection: postpneumonectomy pulmonary edema and postpneumonectomy syndrome.

    abstract::Bassed on the authors' review of the unusual variants of PPS and the body of published experience, a revision of the current classification scheme for PPS into a more comprehensive form is justified as follows: (1) by the nature of obstruction; and (2) by the time of onset. This classification encompasses early and la...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2006.05.001

    authors: Villeneuve PJ,Sundaresan S

    更新日期:2006-08-01 00:00:00

  • Surgical resection of lung cancer in the elderly.

    abstract::Assessment for thoracic surgery in elderly patients should be based on physiologic rather than chronologic age. Thoracic surgery has been shown to be safe in selected elderly patients, and age should not be a contraindication to a therapy that offers the best chance of cure for patients with early-stage cancer. A targ...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2014.07.001

    authors: Bravo-Iñiguez C,Perez Martinez M,Armstrong KW,Jaklitsch MT

    更新日期:2014-11-01 00:00:00

  • Preoperative and postoperative pulmonary rehabilitation in lung cancer patients.

    abstract::The benefits derived from comprehensive PR, when applied to patients who have lung cancer, should have significant impact on both survival and health status. Because PR is known to improve exercise capacity, it is reasonable to expect that this treatment modality may provide more patients with a potential cure. In add...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2007.10.003

    authors: Nici L

    更新日期:2008-02-01 00:00:00

  • The Surgeon as Educator.

    abstract::Surgical education in 2019 faces may challenges to maintain the high standards of excellence achieved in prior generations of learners and trainers in cardiothoracic surgery. This compendium hopes to review the current and future strategies in surgical education. The topics include the adult learner, assessing compete...

    journal_title:Thoracic surgery clinics

    pub_type: 历史文章,杂志文章,评审

    doi:10.1016/j.thorsurg.2019.03.001

    authors: Verrier ED

    更新日期:2019-08-01 00:00:00

  • Lung cancer screening: the European perspective.

    abstract::European studies have contributed significantly to the understanding of lung cancer screening. Smoking within screening, quality of life, nodule management, minimally invasive treatments, cancer prevention programs, and risk models have been extensively investigated by European groups. Mortality data from European scr...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2014.12.002

    authors: Veronesi G

    更新日期:2015-05-01 00:00:00

  • Uniportal Video-Assisted Transcervical Thymectomy.

    abstract::Surgery has proven superiority over medical management for patients with nonthymomatous myasthenia gravis. The key is complete resection of the gland, which can be achieved with various techniques. The uniportal video-assisted transcervical technique allows minimally invasive surgery with a low complication rate, a go...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2018.12.009

    authors: Lemaître PH,Keshavjee S

    更新日期:2019-05-01 00:00:00

  • Adjuvant and Neoadjuvant Immunotherapy in Non-small Cell Lung Cancer.

    abstract::The advent of immune checkpoint blockade has revolutionized the management of advanced non-small cell lung cancer (NSCLC). Impressive results in the metastatic setting have prompted substantial interest in the application of these agents in earlier-stage disease. Applications of checkpoint blockade in the adjuvant set...

    journal_title:Thoracic surgery clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.thorsurg.2020.01.001

    authors: Broderick SR

    更新日期:2020-05-01 00:00:00