Abstract:
:In spite of numerous clinical trials, the jury is still out on the value of induction therapy for locally advanced lung cancer. We elected to address this topic from the multifaceted views of the clinicians often involved in lung cancer management and according the most recent views on locally advanced NSCLC. The concept of a prognostic stratification of N2 disease subsets, especially single vs multiple zone, has been introduced and this may lead to a new interpretation of locally advanced NSCLC. Ten crucial issues were identified that may have an impact on the approach to patients with locally advanced lung cancer in everyday practice.
journal_name
Thorac Surg Clinjournal_title
Thoracic surgery clinicsauthors
Rocco G,Morabito A,Muto Pdoi
10.1016/j.thorsurg.2011.08.010subject
Has Abstractpub_date
2012-02-01 00:00:00pages
67-75, viissue
1eissn
1547-4127issn
1558-5069pii
S1547-4127(11)00098-3journal_volume
22pub_type
杂志文章,评审abstract::Although numerous articles have been written over the past two decades with regard to the treatment of traumatic diaphragmatic hernia, little has actually changed during that time. The ability to make the diagnosis has somewhat improved because of the technologic advances in CT; however, it remains true that the best ...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2007.03.006
更新日期:2007-02-01 00:00:00
abstract::Because the esophagus is a tubular muscular structure only partially filled with air and surrounded by major structures (vessels, lungs, and heart), its radiologic evaluation cannot be performed solely by conventional chest radiograph or barium studies. The emergence of newer techniques has had a dramatic effect on th...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章
doi:10.1016/j.thorsurg.2010.12.007
更新日期:2011-05-01 00:00:00
abstract::Thoracoscopy has afforded a huge advance for upper thoracic sympathetic procedures compared with prior open procedures. Different clinical syndromes of hyperhidrosis exist and require different forms of treatment. The classic severe palmoplantar pattern of hyperhidrosis will not respond effectively in the long term to...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2008.01.005
更新日期:2008-05-01 00:00:00
abstract::The literature shows that, in the hands of experienced thoracoscopic surgeons, VL is a safe operation that offers patients at least comparable complication and survival rates compared with lobectomy by thoracotomy. VL can be performed safely with proven advantages over conventional thoracotomy for lobectomy: smaller i...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2007.03.019
更新日期:2007-05-01 00:00:00
abstract::Nonintubated video-assisted thoracoscopic surgery for the treatment of primary and secondary pneumothorax was first reported in 1997 by Nezu. However, studies on this technique are few. Research in the past 20 years has focused on the perioperative outcomes, including the surgical duration, length of hospital stay, an...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2019.08.001
更新日期:2020-02-01 00:00:00
abstract::The Stretta procedure is safe and effective for the treatment of GERD. There are well-documented clinical trial data supporting its use, including a randomized sham-controlled study, single- and multi-center prospective trials, and community practice reports. The complication rate is within the acceptable range for th...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2005.03.006
更新日期:2005-08-01 00:00:00
abstract::Patients express risk aversion toward surgery, particularly if surgery can lead to lifelong debility and loss of independence. When faced with a guarantee of progressive lung cancer and no alternatives for cure, however, patients are willing to take extremely high risks of postoperative complications and surgery-relat...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章
doi:10.1016/S1547-4127(04)00016-7
更新日期:2004-08-01 00:00:00
abstract::The shortage of adequate organ donors remains a great challenge in clinical lung transplantation. With increasing experience in the medical management and surgical technique of lung transplantation, gradual expansion of the criteria for lung donor selection has occurred with beneficial effects on the donor pool. Inter...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2009.02.006
更新日期:2009-05-01 00:00:00
abstract::Thoracoscopic lobectomy is emerging as the procedure of choice for patients with early stage non-small cell lung cancer, based on advantages in quality of life as well as long-term outcomes. In addition, thoracoscopic lobectomy has been demonstrated to be safe and effective for selected patients with locally advanced ...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2008.04.002
更新日期:2008-08-01 00:00:00
abstract::Staging of malignant pleural mesothelioma has been challenging because of a paucity of cases and poor survival. At least 5 staging systems were proposed before 1990 until the first consensus system was published in 1995. This system used tumor, node, metastasis designations and borrowed heavily from parenchymal lung c...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2020.07.001
更新日期:2020-11-01 00:00:00
abstract::Cervical mediastinoscopy is a frequently used technique to assess the mediastinum, in particular the mediastinal lymph nodes in patients presenting with non-small cell lung cancer (NSCLC). The senior author of this article is credited for developing in 1989 the concept of what is now called videomediastinoscopy. The i...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2010.01.006
更新日期:2010-05-01 00:00:00
abstract::Pleural metastasis is a common occurrence in up to 30% of patients with metastatic cancer. When lung entrapment and loculation of fluid occur, treatment is more difficult and we have named this condition "oncothorax." The malignant adhesions that entrap the lung in an oncothorax are not typically amenable to surgical ...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2017.08.009
更新日期:2018-02-01 00:00:00
abstract::Surgical treatment of idiopathic scoliosis has classically included posterior, anterior, or combined open surgical techniques. In recent years, a videothoracoscopic approach to the spine has been increasingly employed either in combination with the posterior open approach or as a stand-alone treatment including anteri...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2010.01.004
更新日期:2010-05-01 00:00:00
abstract::This article summarizes the pertinent points of tracheal and bronchial anatomy, including the relationships to surrounding structures. Tracheal and bronchial anatomy is essential knowledge for the thoracic surgeon, and an understanding of the anatomic relationships surrounding the airway is crucial to the safe perform...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2006.12.006
更新日期:2007-11-01 00:00:00
abstract::Vertebral body resection for locally advanced lung cancer can be performed with acceptable morbidity and mortality rates, and with improved long-term survival, when combined with chemotherapy and radiation. A consensus has not been reached on either the optimal extent of vertebral resection or the optimal treatment re...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/S1547-4127(04)00009-X
更新日期:2004-05-01 00:00:00
abstract::Curing cancer requires the treatment of metastatic disease. Whether this is a patient with advanced disease and clinically apparent metastases, or if the patient with localized disease is at risk for development of dissemination, failure to control metastasis will result in a poor outcome. Here, we have presented a mo...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2005.12.003
更新日期:2006-05-01 00:00:00
abstract::The current convention is for bilateral one-stage lung volume reduction surgery. Unilateral surgery results in a symptomatic improvement in most patients. A staged approach to the second lung may reduce the risk of surgery and lead to a slower decline in physiologic improvement. The timing of the second operation can ...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2009.02.001
更新日期:2009-05-01 00:00:00
abstract::Esophageal perforation has historically been a devastating condition resulting in high morbidity and mortality. The use of endoluminal therapies to treat esophageal leaks and perforations has grown exponentially over the last decade and offers many advantages over traditional surgical intervention in the appropriate c...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2018.07.002
更新日期:2018-11-01 00:00:00
abstract::Esophageal cancer requires a multimodality treatment approach, with surgical resection a key component in many cases. When it comes to esophagectomy, several approaches and techniques exist, including transhiatal versus transthoracic and open versus minimally invasive. Each approach has its associated risks and advant...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2020.04.010
更新日期:2020-08-01 00:00:00
abstract::Concerns regarding the sequelae of neoadjuvant chemotherapy or chemoradiotherapy on the pleural space and tissue planes had previously deterred the application of video-assisted thoracoscopic (VATS) lobectomy for patients who underwent neoadjuvant therapy. As experience with VATS has increased, however, its applicatio...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2014.07.013
更新日期:2014-11-01 00:00:00
abstract::Anatomic lung segmentectomy is a possible alternative to lobectomy for small (<2 cm) primary lung cancers. Interest in anatomic lung segmentectomy has increased further after the adoption of high-resolution computed tomography and the implementation of lung cancer screening studies, which are increasing the detection ...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2014.02.008
更新日期:2014-05-01 00:00:00
abstract::Tracheobronchomalacia is an uncommon acquired disorder of the central airways. Common symptoms include dyspnea, constant coughing, inability to raise secretions, and recurrent respiratory infections. Evaluation includes an inspiratory-expiratory chest CT (dynamic CT), an awake functional bronchoscopy, and pulmonary fu...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2018.01.006
更新日期:2018-05-01 00:00:00
abstract::With continually increasing health care costs and limited medical resources, there has been increasing focus on shortening hospital stays. Many medical and nonmedical reasons can lead to a delay in hospital discharge after thoracic surgery despite technically successful procedures; common obstacles include inadequate ...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章
doi:10.1016/j.thorsurg.2005.01.007
更新日期:2005-05-01 00:00:00
abstract::Bassed on the authors' review of the unusual variants of PPS and the body of published experience, a revision of the current classification scheme for PPS into a more comprehensive form is justified as follows: (1) by the nature of obstruction; and (2) by the time of onset. This classification encompasses early and la...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2006.05.001
更新日期:2006-08-01 00:00:00
abstract::Assessment for thoracic surgery in elderly patients should be based on physiologic rather than chronologic age. Thoracic surgery has been shown to be safe in selected elderly patients, and age should not be a contraindication to a therapy that offers the best chance of cure for patients with early-stage cancer. A targ...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2014.07.001
更新日期:2014-11-01 00:00:00
abstract::The benefits derived from comprehensive PR, when applied to patients who have lung cancer, should have significant impact on both survival and health status. Because PR is known to improve exercise capacity, it is reasonable to expect that this treatment modality may provide more patients with a potential cure. In add...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2007.10.003
更新日期:2008-02-01 00:00:00
abstract::Surgical education in 2019 faces may challenges to maintain the high standards of excellence achieved in prior generations of learners and trainers in cardiothoracic surgery. This compendium hopes to review the current and future strategies in surgical education. The topics include the adult learner, assessing compete...
journal_title:Thoracic surgery clinics
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.thorsurg.2019.03.001
更新日期:2019-08-01 00:00:00
abstract::European studies have contributed significantly to the understanding of lung cancer screening. Smoking within screening, quality of life, nodule management, minimally invasive treatments, cancer prevention programs, and risk models have been extensively investigated by European groups. Mortality data from European scr...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2014.12.002
更新日期:2015-05-01 00:00:00
abstract::Surgery has proven superiority over medical management for patients with nonthymomatous myasthenia gravis. The key is complete resection of the gland, which can be achieved with various techniques. The uniportal video-assisted transcervical technique allows minimally invasive surgery with a low complication rate, a go...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2018.12.009
更新日期:2019-05-01 00:00:00
abstract::The advent of immune checkpoint blockade has revolutionized the management of advanced non-small cell lung cancer (NSCLC). Impressive results in the metastatic setting have prompted substantial interest in the application of these agents in earlier-stage disease. Applications of checkpoint blockade in the adjuvant set...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2020.01.001
更新日期:2020-05-01 00:00:00