Survival predictors of patients with primary duodenal adenocarcinoma.

Abstract:

:This single-institution experience retrospectively reviewed the outcomes in 21 patients with primary duodenal adenocarcinoma. Twelve patients underwent curative surgery, and 9 patients underwent palliative surgery at the Chiba University Hospital. The maximum follow-up period was 8650 days. All pathologic specimens from endoscopic biopsy and surgical specimens were reviewed and categorized. Twelve (57.1%) patients underwent curative surgery (R0): 4 pancreaticoduodenectomies (PD), 4 pylorus-preserving PDs (PpPD), 2 local resections of the duodenum and 2 endoscopic mucosal resections (EMR). Palliative surgery was performed for 9 patients (42.9%) following gastro-intestinal bypass. The median cause-specific survival times were 1784 days (range 160-8650 days) in the curative surgery group and 261 days (range 27-857 days) in the palliative surgery group (P = 0.0003, log-rank test). The resectability of primary duodenal adenocarcinoma was associated with a smaller tumor size, a lower degree of tumor depth invasiveness, and less spread to the lymph nodes and distant organs.

journal_name

Int Surg

journal_title

International surgery

authors

Kawahira H,Miura F,Saigo K,Matsunaga A,Natsume T,Akai T,Horibe D,Suzuki K,Nabeya Y,Hayashi H,Miyauchi H,Shuto K,Asano T,Matsubara H

doi

10.9738/1381.1

subject

Has Abstract

pub_date

2011-04-01 00:00:00

pages

111-6

issue

2

eissn

0020-8868

issn

2520-2456

journal_volume

96

pub_type

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