Secreted factors from Bifidobacterium animalis subsp. lactis inhibit NF-κB-mediated interleukin-8 gene expression in Caco-2 cells.

Abstract:

:The objective of the present study was to evaluate the anti-inflammatory effects of Bifidobacterium animalis subsp. lactis strain BB12 in stimulated Caco-2 cells and to characterize the factors responsible for these anti-inflammatory effects. Characterization and purification studies indicate that BB12's anti-inflammatory factors might include a 50-kDa proteinaceous compound that is stable under a variety of heat and pH conditions.

journal_name

Appl Environ Microbiol

authors

Wang Z,Wang J,Cheng Y,Liu X,Huang Y

doi

10.1128/AEM.06145-11

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

8171-4

issue

22

eissn

0099-2240

issn

1098-5336

pii

AEM.06145-11

journal_volume

77

pub_type

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