Abstract:
:Cardiac contractility modulation (CCM) is a device therapy for patients with systolic heart failure. CCM therapy applies non-excitatory signals during the absolute refractory period of the heart cycle. It influences myocardial contractility by modulating the regulation of calcium cycling. CCM therapy has been proven to enhance peak VO(2), quality of life and exercise tolerance in patients with congestive heart failure. It can be used as an additional therapy to an implantable cardioverter defibrillator (ICD), if present. CCM therapy should be considered in symptomatic patients with congestive heart failure, a left ventricular ejection fraction ≤35% and NYHA class II-III. Atrial fibrillation, high grade arrhythmias and an AV block of more than 300 ms represent contraindications. Patients with a left bundle branch block of >120 ms should be considered for the implantation of a biventricular ICD prior to implantation of a CCM device.
journal_name
Herzjournal_title
Herzauthors
Tönnis T,Kuck KHdoi
10.1007/s00059-011-3510-zsubject
Has Abstractpub_date
2011-10-01 00:00:00pages
600-7issue
7eissn
0340-9937issn
1615-6692journal_volume
36pub_type
杂志文章,评审相关文献
HERZ文献大全abstract::Interventional treatment of mitral insufficiency has recently become possible on a limited basis. The developed percutaneous procedures aim at minimizing the trauma in high-risk surgical candidates. Echocardiography has a major role in the preinterventional evaluation, during the interventional procedure, and in the p...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-009-3281-y
更新日期:2009-09-01 00:00:00
abstract::Acute myocarditis is a major inflammatory heart disease with a variety of clinical courses from the acute to chronic phases represented by unexpected circulatory deterioration during hospitalization and progression to dilated cardiomyopathy. Predicting these disease courses is important for patient management. However...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-012-3661-6
更新日期:2012-09-01 00:00:00
abstract::The aortic valve consists of three cusps attached to the wall of the aortic root. During the cardiac cycle, the aortic root undergoes complex movements that precede and aid opening and closing of the aortic valve. The aortic valve cusps themselves form thin-walled pocket-like structures, made from specialized tissue w...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-006-2836-4
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:In addition to the genetic complexity of hypertrophic cardiomyopathy (HCM), there must be other disease-modifying factors that contribute to its highly variable clinical and phenotypic expression. The authors aimed to investigate serum thiol/disulphide homeostasis as a proxy for oxidative stress using a nove...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-019-04853-7
更新日期:2019-12-09 00:00:00
abstract::The term diabetic cardiomyopathy was initially introduced in the 1980s when evidence was found that diabetes leads to a distinct cardiomyopathy, independent of coronary artery disease or hypertension. The detection of diabetic cardiomyopathy using echocardiography is challenging because no pathognomonic signs exist; h...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-012-3726-6
更新日期:2013-02-01 00:00:00
abstract::Blood pressure, the central parameter in the diagnosis of arterial hypertension, is subject to a high degree of variability. The dilemma for the evaluating physician is that he has no true value for the resting blood pressure that is both comparable and reproducible. Reproducibility, however, is an essential requireme...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1987-04-01 00:00:00
abstract::MR with its various imaging protocols including spin-echo MR-imaging, gradient MR imaging, flow-mapping and MR angiography is the ideal tool for noninvasive assessment of any kind of aortic diseases. The technique allows to image the aorta both in the thoracic cage and in the abdominal aspects better than any other to...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s000590050026
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:The German national guidelines on chronic heart failure provide treatment recommendations to physicians and reflect the current level of evidence; however, it is questionable to what extent these recommendations are applied in the routine practice and what the effect of guideline adherence on mortality is. ...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-016-4401-0
更新日期:2016-11-01 00:00:00
abstract::Heart failure is one of the leading diseases in internal medicine worldwide. Because of the increase in population aging, the incidence and prevalence of heart insufficiency is rising annually and is now the most frequent individual diagnosis among hospitalized patients in Germany. The mortality rate has recently been...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-018-4715-1
更新日期:2020-04-01 00:00:00
abstract::Our 19th century predecessors considered the aorta as a source of cardiovascular pain associated with inflammatory aortitis, arterial hypertension, aortic aneurysms, aortic dissection, and aortic valve disease. However, during the 20th century epidemic of coronary artery disease clinicians became concerned with the sy...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/BF03043853
更新日期:1999-04-01 00:00:00
abstract::Arrhythmogenic right ventricular cardiomyopathy is a primary heart muscle disease characterized by progressive myocardial atrophy of the right ventricle, with transmural fatty or fibrofatty replacement, either segmental or diffuse, accounting for electrical instability at risk of life-threatening ventricular arrhythmi...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s000590050008
更新日期:2000-05-01 00:00:00
abstract::Spontaneous rupture of coronary arteries as well as coronary perforation during percutaneous interventions are rare but potentially life-threatening incidents often resulting in emergency surgery. Frequency of acute perforation due to therapeutic catheterization varies according to the devices employed. With conventio...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/BF03044364
更新日期:1998-08-01 00:00:00
abstract::Based on the epidemiologic data of the Framingham heart study, arterial hypertension and coronary artery disease are the most frequent etiologic factors for the development of heart failure. In the pressure overloaded heart, hypertrophic growth of the myocardium includes the enlargement of cardiac myocytes stimulated ...
journal_title:Herz
pub_type: 杂志文章,评审
doi:
更新日期:1995-10-01 00:00:00
abstract::Incorporating prognostically related auscultatory, M-mode, 2DE and recent Doppler echocardiographic features, the following strict criteria for establishing the diagnosis of mitral valve prolapse (MVP) have been advanced: 1. auscultatory; mid-to-late systolic clicks and a late systolic murmur at the apex or mid-to-lat...
journal_title:Herz
pub_type: 杂志文章,评审
doi:
更新日期:1988-10-01 00:00:00
abstract::Although rarely reported, acute instent thrombosis can be life threatening, especially in cases where there are no ST segment changes. For this reason, careful history taking, follow-up, and prompt coronary angiography may be lifesaving. Herein, a case of acute stent thrombosis with no ST segment changes on electrocar...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-011-3526-4
更新日期:2012-05-01 00:00:00
abstract::Coronary artery disease is still the no. 1 killer in the developed countries and must thus be detected and treated at an earlier stage. If coronary artery disease is advanced, patients have to be examined regarding the need for revascularization. For secondary prevention, of course, an optimal change of life style and...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/pl00001975
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:The radiation risk of patients undergoing invasive cardiology remains considerable and includes skin injuries and cancer. To date, submillisievert coronary angiography has not been considered feasible. PATIENTS AND METHODS:In 2011, we compared results from 100 consecutive patients undergoing elective corona...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-013-4015-8
更新日期:2015-05-01 00:00:00
abstract::Doppler echocardiography enables noninvasive determination of blood velocity and flow area through which quantitation of blood flow in vessels and across valvular orifices can be achieved. The stroke volume is rendered as the product of the flow area and the area beneath the velocity curve; on taking the heart rate in...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1986-10-01 00:00:00
abstract::Formerly the term alcoholism has been defined only by alcohol-related conditions. About 20 years ago a WHO committee recommended to differentiate between alcohol abuse and alcohol dependence. The new classifications and manuals followed this proposal: Criteria for alcohol abuse are still alcohol sequelae whereas alcoh...
journal_title:Herz
pub_type: 杂志文章,评审
doi:
更新日期:1996-08-01 00:00:00
abstract:UNLABELLED:Due to the increasing number of elderly as well as chronically-ill patients, venous thrombosis assumes an increasing role as a typical complication of many courses of disease. Postoperatively, in patients without anticoagulation, fibrinogen tests show venous thrombosis in the lower extremities in up to 50% b...
journal_title:Herz
pub_type: 杂志文章,评审
doi:
更新日期:1989-12-01 00:00:00
abstract::Of 89 children with angiographically-documented pulmonic stenosis and intact ventricular septum (PST), 76 (85.4%) had valvular, 11 (12.4%) infundibular and 2 (2%) had supravalvular lesions. Standard, p. a. view, chest X-rays of children with a mean age of 6 7/12 years were evaluated with respect to 1. cardiac enlargem...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1980-10-01 00:00:00
abstract:BACKGROUND:The Braunwald classification and TIMI (Thrombolysis In Myocardial Infarction) risk score are used to stratify cardiovascular risk in patients with unstable angina (UA). However, these scores have a limited capacity in the practice of cardiology. OBJECTIVES:This study sought to develop a new score, based on ...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-014-4141-y
更新日期:2015-03-01 00:00:00
abstract:IMPORTANCE:Anxiety and depression are frequent problems in patients with heart diseases. Prevalences vary between 15 and 50%, depending on diagnostic criteria as well as on sociodemographic and medical patient characteristics. During the last 10-15 years, a large number of studies have shown that anxiety and depression...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-001-2300-4
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:: Drug-eluting stents (DES) have been shown to reduce the risk of in-stent stenosis, one of the major problems of percutaneous coronary intervention (PCI) with implantation of baremetal stents. DES are approved in Germany since 2002. The following study is based on data of the ALKK PCI registry a...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-008-3097-1
更新日期:2008-09-01 00:00:00
abstract::While there is generell agreement that patients with aortic stenosis (AS) who have already developed symptoms, such as exertional dyspnea, angina or dizziness and syncope, require urgent surgery because of their otherwise very poor outcome, the management of asymptomatic severe AS remains controversial. Although preve...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-006-2871-1
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The endothelial lining is a confluent monolayer of thin and rhomboid-shaped cells, that covers the inner surface of all blood vessels. However, the essential role of endothelial cells in all aspects of cardiovascular physiology, homeostasis and the pathogenesis of most cardiovascular diseases no ...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-004-2418-2
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND:Modern high-resolution imaging techniques have provided new insights into the pathogenesis of aortic dissection during recent years. Distinct pathologic entities or potential precursors of classic false-lumen aortic dissection such as intramural hematoma or penetrating atherosclerotic ulcer have been identif...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-002-2406-3
更新日期:2002-09-01 00:00:00
abstract::The impaired cardiac performance in patients with congestive cardiac failure may be improved by the introduction of inotropic therapy. Dopamine and dobutamine are both potent cardiac stimulants although their haemodynamic profile is different. Dobutamine would appear to be the more appropriate choice in cardiac failur...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1983-02-01 00:00:00
abstract::Coronary artery disease (CAD) is a leading cause of morbidity and mortality in western countries and is of significant socio-economic importance due to its increasing prevalence. Until percutaneous coronary interventions (PCI) were established, CAD could only be treated by surgical revascularization or pharmacological...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-013-3917-9
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:Epidemiologic studies have found an association between overweight and increased mortality arising primarily from cardiovascular disorders. A major determinant is a chronically raised sympathetic nervous system activity which can arise from calorie intake-dependent and -independent mechanisms. Calorie-depend...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-003-2517-5
更新日期:2003-12-01 00:00:00