Personal genome testing: test characteristics to clarify the discourse on ethical, legal and societal issues.

abstract：BACKGROUND:Studies on informed consent to medical research conducted in low or middle-income settings have increased, including empirical investigations of consent to genetic research. We investigated voluntary participation and comprehension of informed consent among women involved in a genetic epidemiological study o...

journal_title：BMC medical ethics

authors： Marshall PA,Adebamowo CA,Adeyemo AA,Ogundiran TO,Strenski T,Zhou J,Rotimi CN

更新日期：2014-05-13 00:00:00

abstract：BACKGROUND:Despite the growing recognition for the need to improve the health of prisoners in Canada and the need for health research, there has been little discussion of the ethical issues with regards to health research with prisoners in Canada. The purpose of this paper is to encourage a national conversation about ...

journal_title：BMC medical ethics

authors： Silva DS,Matheson FI,Lavery JV

更新日期：2017-04-27 00:00:00

abstract：BACKGROUND:Ethics committees typically apply the common principles of autonomy, nonmaleficence, beneficence and justice to research proposals but with variable weighting and interpretation. This paper reports a comparison of ethical requirements in an international cross-cultural study and discusses their implications....

journal_title：BMC medical ethics

authors： Goodyear-Smith F,Lobb B,Davies G,Nachson I,Seelau SM

更新日期：2002-04-19 00:00:00

abstract：BACKGROUND:Institutional review boards (IRBs) distinguish health care quality improvement (QI) and health care quality improvement research (QIR) based primarily on the rigor of the methods used and the purported generalizability of the knowledge gained. Neither of these criteria holds up upon scrutiny. Rather, this ap...

journal_title：BMC medical ethics

authors： Fiscella K,Tobin JN,Carroll JK,He H,Ogedegbe G

更新日期：2015-09-17 00:00:00

abstract：BACKGROUND:A requisite for ethical human subjects research is that participation should be informed and voluntary. Participation during the informed consent process by way of asking questions is an indicator of the extent to which consent is informed. AIMS:The aims of this study were to assess the extent to which pare...

journal_title：BMC medical ethics

authors： Rajaraman D,Jesuraj N,Geiter L,Bennett S,Grewal HM,Vaz M,TB Trials Study Group.

更新日期：2011-02-15 00:00:00

abstract：BACKGROUND:The ethical principle of justice demands that resources be distributed equally and based on evidence. Guidelines regarding forgoing of CPR are unavailable and there is large variance in the reported rates of attempted CPR in in-hospital cardiac arrest. The main objective of this work was to study whether loc...

journal_title：BMC medical ethics

authors： Ozer J,Alon G,Leykin D,Varon J,Aharonson-Daniel L,Einav S

更新日期：2019-12-26 00:00:00

abstract：BACKGROUND:Scientific advances have resulted in more complex medical systems, which in turn have led to an increase in the number of patient safety incidents (PSIs). In this environment, the importance of honest disclosure of PSIs is rising, which highlight the need to settle a reliable system. This study aimed to inve...

journal_title：BMC medical ethics

authors： Kim Y,Lee E

更新日期：2020-10-27 00:00:00

abstract：BACKGROUND:Public satisfaction with policy process influences the legitimacy and acceptance of policies, and conditions the future political process, especially when contending ethical value judgments are involved. On the other hand, public involvement is required if effective policy is to be developed and accepted. M...

journal_title：BMC medical ethics

authors： Sato H,Akabayashi A,Kai I

更新日期：2005-01-20 00:00:00

abstract：BACKGROUND:In 2009, Dr. Paolo Zamboni proposed chronic cerebrospinal venous insufficiency (CCSVI) as a possible cause of multiple sclerosis (MS). Although his theory and the associated treatment ("liberation therapy") received little more than passing interest in the international scientific and medical communities, hi...

journal_title：BMC medical ethics

authors： Pullman D,Zarzeczny A,Picard A

更新日期：2013-02-12 00:00:00

abstract：BACKGROUND:Community consultation is increasingly recommended, and in some cases, required by ethical review boards for research that involves higher levels of ethical risk such as international research and research with vulnerable populations. In designing a randomised control trial of a mental health intervention us...

journal_title：BMC medical ethics

authors： Shanks L,Moroni C,Rivera IC,Price D,Clementine SB,Pintaldi G

更新日期：2015-06-02 00:00:00

abstract：BACKGROUND:France has long been a country of immigration and in some respects may be seen to have a generous policy with respect to asylum seekers and access to health care for migrants. The French state notably provides healthcare access for undocumented migrants, through state medical aid and since 1998 has had a hum...

journal_title：BMC medical ethics

authors： Cailhol J,Lebon MC,Sherlaw W

更新日期：2020-07-13 00:00:00

abstract：BACKGROUND:When conducting research with Indigenous populations consent should be sought from both individual participants and the local community. We aimed to search and summarise the literature about methods for seeking consent for research with Indigenous populations. METHODS:A systematic literature search was cond...

journal_title：BMC medical ethics

authors： Fitzpatrick EF,Martiniuk AL,D'Antoine H,Oscar J,Carter M,Elliott EJ

更新日期：2016-10-22 00:00:00

abstract：BACKGROUND:We analyzed the patients' perception of prenatal diagnosis of fetal cardiac pathology, and the reasons for choosing to continue with pregnancy despite being eligible to receive a medical termination of pregnancy. We also identified the challenges, the motives interfering in decision-making, and the consequen...

journal_title：BMC medical ethics

authors： Abi Tayeh G,Jouannic JM,Mansour F,Kesrouani A,Attieh E

更新日期：2018-05-02 00:00:00

abstract：BACKGROUND:The work of Research Ethics Boards (REBs), especially when involving genetics research and biobanks, has become more challenging with the growth of biotechnology and biomedical research. Some REBs have even rejected research projects where the use of a biobank with coded samples was an integral part of the s...

journal_title：BMC medical ethics

authors： Auray-Blais C,Patenaude J

更新日期：2006-04-06 00:00:00

abstract：BACKGROUND:Regardless of national contexts, the institutions responsible for research ethics, founded on international regulations, are all expected to be structured and to operate in a common way. Our experience with several countries on different continents, however, has raised questions in this regard. This article ...

journal_title：BMC medical ethics

authors： Sambiéni NE

更新日期：2018-06-15 00:00:00

abstract：BACKGROUND:Making particular use of Shale's analysis, this paper discusses the notion of leadership in the context of palliative medicine. Whilst offering a critical perspective, I build on the philosophy of palliative care offered by Randall and Downie and suggest that the normative structure of this medical specialit...

journal_title：BMC medical ethics

authors： Emmerich N

更新日期：2018-06-05 00:00:00

abstract：BACKGROUND:Various forms of Clinical Ethics Support (CES) have been developed in health care organizations. Over the past years, increasing attention has been paid to the question of how to foster the quality of ethics support. In the Netherlands, a CES quality assessment project based on a responsive evaluation design...

journal_title：BMC medical ethics

authors： Van Baarle EM,Potma MC,van Hoek MEC,Hartman LA,Molewijk BAC,van Gurp JLP

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Donepezil, an acetylcholinesterase inhibitor used in the treatment of Alzheimer's disease, has been widely cited in media and bioethics literature on cognitive enhancement (CE) as having the potential to improve the cognitive ability of healthy individuals. In both literatures, this claim has been repeatedly...

journal_title：BMC medical ethics

authors： Wade L,Forlini C,Racine E

更新日期：2014-05-12 00:00:00

abstract：BACKGROUND:Africa continues to bear a disproportionate share of the global HIV/AIDS, tuberculosis (TB) and malaria burden. The development and distribution of safe, effective and affordable vaccines is critical to reduce these epidemics. However, conducting HIV/AIDS, TB, and/or malaria vaccine trials simultaneously in ...

journal_title：BMC medical ethics

authors： Mamotte N,Wassenaar D,Koen J,Essack Z

更新日期：2010-03-09 00:00:00

abstract：BACKGROUND:Patient outcome after serious brain injury is highly variable. Following a period of coma, some patients recover while others progress into a vegetative state (unresponsive wakefulness syndrome) or minimally conscious state. In both cases, assessment is difficult and misdiagnosis may be as high as 43%. Recen...

journal_title：BMC medical ethics

authors： Weijer C,Peterson A,Webster F,Graham M,Cruse D,Fernández-Espejo D,Gofton T,Gonzalez-Lara LE,Lazosky A,Naci L,Norton L,Speechley K,Young B,Owen AM

更新日期：2014-05-20 00:00:00

abstract：BACKGROUND:Differences in perception and potential disagreements between parents and professionals regarding the attitude for resuscitation at the limit of viability are common. This study evaluated in healthcare professionals whether the decision to resuscitate at the limit of viability (intensive care versus comfort ...

journal_title：BMC medical ethics

authors： Papadimitriou V,Tosello B,Pfister R

更新日期：2019-10-22 00:00:00

abstract：BACKGROUND:Expectations of receiving personal health information as a fringe benefit of biospecimen donation-termed diagnostic misconception-are increasingly documented. We developed an instrument measuring conflation of observational biospecimen-based research and clinical care for use with Latino communities, who may...

journal_title：BMC medical ethics

authors： Knerr S,Ceballos RM

更新日期：2015-07-17 00:00:00

abstract：BACKGROUND:There is a permanent need to evaluate and develop the ethical quality of scientific research and to widen knowledge about the effects of ethical issues. Therefore we evaluated whether informed consent is related to implementation and success in a lifestyle intervention study with older research participants....

journal_title：BMC medical ethics

authors： Länsimies-Antikainen H,Pietilä AM,Laitinen T,Kiviniemi V,Rauramaa R

更新日期：2010-06-08 00:00:00

abstract：BACKGROUND:The boundaries between health-related research and practice have become blurred as initiatives traditionally considered to be practice (e.g., quality improvement, program evaluation) increasingly use the same methodology as research. Further, the application of different ethical requirements based on this di...

journal_title：BMC medical ethics

authors： Ondrusek NK,Willison DJ,Haroun V,Bell JA,Bornbaum CC

更新日期：2015-07-07 00:00:00

abstract：BACKGROUND:In most Anglophone nations, policy and law increasingly foster an autonomy-based model, raising issues for large numbers of people who fail to fit the paradigm, and indicating problems in translating practical and theoretical understandings of 'good death' to policy. Three exemplar populations are frail olde...

journal_title：BMC medical ethics

authors： Birchley G,Jones K,Huxtable R,Dixon J,Kitzinger J,Clare L

更新日期：2016-07-27 00:00:00

abstract：BACKGROUND:Social media and Internet technologies present several emerging and ill-explored issues for a modern healthcare workforce. One issue is patient-targeted Googling (PTG), which involves a healthcare professional using a social networking site (SNS) or publicly available search engine to find patient informatio...

journal_title：BMC medical ethics

authors： Chester AN,Walthert SE,Gallagher SJ,Anderson LC,Stitely ML

更新日期：2017-12-04 00:00:00

abstract：BACKGROUND:Health checks or health screenings identify (risk factors for) disease in people without a specific medical indication. So far, the perspective of (potential) health check users has remained underexposed in discussions about the ethics and regulation of health checks. METHODS:In 2017, we conducted a qualita...

journal_title：BMC medical ethics

authors： Stol YH,Asscher ECA,Schermer MHN

更新日期：2018-06-22 00:00:00

abstract：BACKGROUND:Intensive care physicians often must rely on substitute decision makers to address all dimensions of the construct of "best interest" for incapable, critically ill patients. This task involves identifying prior wishes and to facilitate the substitute decision maker's understanding of the incapable patient's ...

journal_title：BMC medical ethics

authors： Ratnapalan M,Cooper AB,Scales DC,Pinto R

更新日期：2010-02-10 00:00:00

abstract：BACKGROUND:Clinical Ethics Committees (CECs) are well established at healthcare institutions in resource-rich countries. However, there is limited information on established CECs in resource poor countries, especially in Africa. This study aimed to establish baseline data regarding existing formal CECs in Africa to rai...

journal_title：BMC medical ethics

authors： Moodley K,Kabanda SM,Soldaat L,Kleinsmidt A,Obasa AE,Kling S

更新日期：2020-11-18 00:00:00

abstract：BACKGROUND:South Africa currently has a pluralistic health care system with separate public and private sectors. It is, however, moving towards a socialised model with the introduction of National Health Insurance. The South African legislative environment has changed recently with the promulgation of the Consumer Prot...

journal_title：BMC medical ethics

authors： Rowe K,Moodley K

更新日期：2013-03-21 00:00:00