Abstract：
BACKGROUND:Causes of pericardial effusion requiring pericardiocentesis are very complex; a summary of 140 patients, especially those having iatrogenic pericardial effusion, is rare. METHODS:We prospectively analyzed the clinical data and etiology of moderate to large pericardial effusion requiring pericardiocentesis and drainage in 140 consecutive Han Chinese patients from January 2007 to December 2009. RESULTS:Pericardiocentesis was successfully performed and effective in all patients. There were 9 cases with transudates, while the remaining 131 cases were diagnosed with exudates (neoplastic in 54 patients, tuberculous in 40 patients, 9 cases of connective tissue diseases, 12 cases undergoing cardiac catheterization, and 8 cases of acute myocardial infarction). Among the 54 malignancies, 30 patients had lung cancer, 7 had breast cancer, and 4 had liver cancer. No differences in the clinical characteristics and the results of routine and biochemistry studies in the pericardial fluid between tuberculous and malignant groups were found. Of the 12 patients undergoing cardiac catheterization, 6 cases had undergone catheter ablation for tachycardia and 4 cases had undergone percutaneous coronary intervention. The 6 patients undergoing catheter ablation were women and the ratio of pericardial effusion was higher in women (6/436) than in men (0/462; p<0.05). Pericardiocentesis and drainage was effective in the 6 patients who underwent catheter ablation, and the remaining 6 patients underwent surgical intervention after pericardiocentesis and drainage. All 8 patients with acute myocardial infarction died during hospitalization. CONCLUSION:In China, most moderate to large pericardial effusions requiring pericardiocentesis and drainage were exudates and bloody, which were mainly caused by malignancy and tuberculosis. However, the incidence of iatrogenic pericardial effusion has been increasing and should not be ignored. Pericardiocentesis and drainage were effective.
journal_name
Herzjournal_title
Herzauthors
Ma W,Liu J,Zeng Y,Chen S,Zheng Y,Ye S,Lan L,Liu Q,Weig HJ,Liu Qdoi
10.1007/s00059-011-3428-5subject
Has Abstractpub_date
2012-03-01 00:00:00pages
183-7issue
2eissn
0340-9937issn
1615-6692journal_volume
37pub_type
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