A blue native-PAGE analysis of membrane protein complexes in Clostridium thermocellum.

abstract：BACKGROUND:HSV-1 is a common pathogen that infects 50-90% of the human population worldwide. HSV-1 causes numerous infection-related diseases, some of which are severely life-threatening. There are antiviral medications with activity against HSV-1. However, with the emergence of drug-resistant mutant strains of HSV-1, ...

journal_title：BMC microbiology

authors： Huang Q,Hou J,Yang P,Yan J,Yu X,Zhuo Y,He S,Xu F

更新日期：2019-12-07 00:00:00

abstract：BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) is known as a leading cause of morbidity and mortality. Investigation of the MRSA's virulence and resistance mechanisms is a continuing concern toward controlling such burdens through using high throughput whole Genome Sequencing (WGS) and molecular diagnost...

journal_title：BMC microbiology

authors： Ali MS,Isa NM,Abedelrhman FM,Alyas TB,Mohammed SE,Ahmed AE,Ahmed ZSA,Lau NS,Garbi MI,Amirul AA,Seed AO,Omer RA,Mohamed SB

更新日期：2019-06-11 00:00:00

abstract：BACKGROUND:Mob family proteins are conserved between animals, plants and fungi and are essential for the activation of NDR kinases that control crucial cellular processes like cytokinesis, proliferation and morphology. RESULTS:We identified a hypomorphic allele of ChMOB2 in a random insertional mutant (vir-88) of the ...

journal_title：BMC microbiology

authors： Schmidpeter J,Dahl M,Hofmann J,Koch C

更新日期：2017-01-19 00:00:00

abstract：BACKGROUND:Tsetse flies (Diptera: Glossinidae) are solely responsible for the transmission of African trypanosomes, causative agents of sleeping sickness in humans and nagana in livestock. Due to the lack of efficient vaccines and the emergence of drug resistance, vector control approaches such as the sterile insect te...

journal_title：BMC microbiology

authors： Augustinos AA,Meki IK,Demirbas-Uzel G,Ouédraogo GMS,Saridaki A,Tsiamis G,Parker AG,Abd-Alla AMM,Bourtzis K

更新日期：2018-11-23 00:00:00

abstract：BACKGROUND:Streptococcus canis is an important opportunistic pathogen of dogs and cats that can also infect a wide range of additional mammals including cows where it can cause mastitis. It is also an emerging human pathogen. RESULTS:Here we provide characterization of the first genome sequence for this species, strai...

journal_title：BMC microbiology

authors： Richards VP,Zadoks RN,Pavinski Bitar PD,Lefébure T,Lang P,Werner B,Tikofsky L,Moroni P,Stanhope MJ

更新日期：2012-12-18 00:00:00

abstract：BACKGROUND:Brucellosis incidence in China is divided into three stages: high incidence (1950s-1960s), decline (1970s-1980s), and re-emergence (1990s-2010s). At the re-emergence stage, Brucellosis incidence grew exponentially and spread to all 32 provinces. We describe the magnitude and the etiological distribution chan...

journal_title：BMC microbiology

authors： Piao DR,Liu X,Di DD,Xiao P,Zhao ZZ,Xu LQ,Tian GZ,Zhao HY,Fan WX,Cui BY,Jiang H

更新日期：2018-01-10 00:00:00

abstract：BACKGROUND:The aim of this study was to identify mutations of rpoB, katG, inhA and ahp-genes associated Mycobacterium tuberculosis resistance to rifampicin (RIF) and isoniazid (INH) in Kyrgyz Republic. We studied 633 smear samples from the primary pulmonary tuberculosis (TB) patients. We verified Mycobacterium tubercul...

journal_title：BMC microbiology

authors： Isakova J,Sovkhozova N,Vinnikov D,Goncharova Z,Talaibekova E,Aldasheva N,Aldashev A

更新日期：2018-03-22 00:00:00

abstract：BACKGROUND:The cell tropism of Brucella abortus, a causative agent of brucellosis and facultative intracellular pathogen, in the placenta is thought to be a key event of infectious abortion, although the molecular mechanism for this is largely unknown. There is a higher degree of bacterial colonization in the placenta ...

journal_title：BMC microbiology

authors： Watanabe K,Tachibana M,Tanaka S,Furuoka H,Horiuchi M,Suzuki H,Watarai M

更新日期：2008-12-05 00:00:00

abstract：BACKGROUND:Acetic acid has been used to clean and disinfect surfaces in the household for many decades. The antimicrobial efficacy of cleaning procedures can be considered particularly important for young, old, pregnant, immunocompromised people, but may also concern other groups, particularly with regards to the COVID...

journal_title：BMC microbiology

authors： Zinn MK,Bockmühl D

更新日期：2020-08-26 00:00:00

abstract：BACKGROUND:The increase in resistance to antibiotics among disease-causing bacteria necessitates the development of alternative antimicrobial approaches such as the use of light-activated antimicrobial agents (LAAAs). Light of an appropriate wavelength activates the LAAA to produce cytotoxic species which can then caus...

journal_title：BMC microbiology

authors： Omar GS,Wilson M,Nair SP

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Next-generation sequencing platforms have revolutionised our ability to investigate the microbiota composition of complex environments, frequently through 16S rRNA gene sequencing of the bacterial component of the community. Numerous factors, including DNA extraction method, primer sequences and sequencing p...

journal_title：BMC microbiology

authors： Fouhy F,Clooney AG,Stanton C,Claesson MJ,Cotter PD

更新日期：2016-06-24 00:00:00

abstract：BACKGROUND:Pseudomonas fuscovaginae (Pfv) is an emerging plant pathogen of rice and also of other gramineae plants. It causes sheath brown rot disease in rice with symptoms that are characterized by brown lesions on the flag leaf sheath, grain discoloration and sterility. It was first isolated as a high altitude pathog...

journal_title：BMC microbiology

authors： Patel HK,Matiuzzo M,Bertani I,Bigirimana Vde P,Ash GJ,Höfte M,Venturi V

更新日期：2014-11-14 00:00:00

abstract：BACKGROUND:Central nervous system disease is the most serious form of tuberculosis, and is associated with high mortality and severe neurological sequelae. Though recent clinical reports suggest an association of distinct Mycobacterium tuberculosis strains with central nervous system disease, the microbial virulence fa...

journal_title：BMC microbiology

authors： Be NA,Bishai WR,Jain SK

更新日期：2012-01-13 00:00:00

abstract：BACKGROUND:It is known that insects and crustaceans can carry simultaneous, active infections of two or more viruses without showing signs of disease, but it was not clear whether co-infecting viruses occupied the same cells or different cells in common target tissues. Our previous work showed that successive challenge...

journal_title：BMC microbiology

authors： Kanthong N,Khemnu N,Pattanakitsakul SN,Malasit P,Flegel TW

更新日期：2010-01-20 00:00:00

abstract：BACKGROUND:GeoChip 3.0, a microbial functional gene array, containing ~28,000 oligonucleotide probes and targeting ~57,000 sequences from 292 functional gene families, provided a powerful tool for researching microbial community structure in natural environments. The alpine meadow is a dominant plant community in the Q...

journal_title：BMC microbiology

authors： Zhang Y,Lu Z,Liu S,Yang Y,He Z,Ren Z,Zhou J,Li D

更新日期：2013-03-29 00:00:00

abstract：BACKGROUND:Chlortetracycline (CTC) is one of the commercially important tetracyclines (TCs) family product and is mainly produced by Streptomyces. CTC is still in a great demand due to its broad-spectrum activity against pathogens. Engineering transcriptional control allows the cell to allocate its valuable resources t...

journal_title：BMC microbiology

authors： Kong L,Liu J,Zheng X,Deng Z,You D

更新日期：2019-12-10 00:00:00

abstract：BACKGROUND:Fungi are the second most abundant type of human pathogens. Invasive fungal pathogens are leading causes of life-threatening infections in clinical settings. Toxicity to the host and drug-resistance are two major deleterious issues associated with existing antifungal agents. Increasing a host's tolerance and...

journal_title：BMC microbiology

authors： Kidane YH,Lawrence C,Murali TM

更新日期：2013-10-07 00:00:00

abstract：BACKGROUND:A common assumption of microorganisms is that laboratory stocks will remain genetically and phenotypically constant over time, and across laboratories. It is becoming increasingly clear, however, that mutations can ruin strain integrity and drive the divergence or "domestication" of stocks. Since its discove...

journal_title：BMC microbiology

authors： Carroll SM,Xue KS,Marx CJ

更新日期：2014-01-02 00:00:00

abstract：BACKGROUND:Abundant populations of bacteria have been observed on Mir and the International Space Station. While some experiments have shown that bacteria cultured during spaceflight exhibit a range of potentially troublesome characteristics, including increases in growth, antibiotic resistance and virulence, other stu...

journal_title：BMC microbiology

authors： Kim W,Tengra FK,Shong J,Marchand N,Chan HK,Young Z,Pangule RC,Parra M,Dordick JS,Plawsky JL,Collins CH

更新日期：2013-11-06 00:00:00

abstract：BACKGROUND:Pectobacterium carotovorum subsp. carotovorum is a phytopathogenic enterobacterium responsible for soft rot, a disease characterized by extensive maceration of the affected plant tissue. This species also produces two or more antibacterial substances called bacteriocins, which enhance its competitiveness aga...

journal_title：BMC microbiology

authors： Chan YC,Wu HP,Chuang DY

更新日期：2009-08-27 00:00:00

abstract：BACKGROUND:Rhizobium tropici strain PRF 81 (= SEMIA 4080) has been used in commercial inoculants for application to common-bean crops in Brazil since 1998, due to its high efficiency in fixing nitrogen, competitiveness against indigenous rhizobial populations and capacity to adapt to stressful tropical conditions, repr...

journal_title：BMC microbiology

authors： Gomes DF,Batista JS,Schiavon AL,Andrade DS,Hungria M

更新日期：2012-05-30 00:00:00

abstract：BACKGROUND:The native microflora associated with mosquitoes have important roles in mosquito development and vector competence. Sequencing of bacterial V3 region from 16S rRNA genes across the developmental stages of Culex mosquitoes (early and late larval instars, pupae and adults) was used to test the hypothesis that...

journal_title：BMC microbiology

authors： Duguma D,Hall MW,Rugman-Jones P,Stouthamer R,Terenius O,Neufeld JD,Walton WE

更新日期：2015-07-24 00:00:00

abstract：BACKGROUND:Multi-locus sequence typing (MLST) is a portable, broadly applicable method for classifying bacterial isolates at an intra-species level. This methodology provides clinical and scientific investigators with a standardized means of monitoring evolution within bacterial populations. MLST uses the DNA sequences...

journal_title：BMC microbiology

authors： Adamiak P,Vanderkooi OG,Kellner JD,Schryvers AB,Bettinger JA,Alcantara J

更新日期：2014-06-03 00:00:00

abstract：BACKGROUND:Exposure of cells to environmental stress conditions can lead to the interruption of several intracellular processes, in particular those performed by macromolecular complexes such as the spliceosome. RESULTS:During nucleotide sequencing of cDNA libraries constructed using RNA isolated from B. emersonii cel...

journal_title：BMC microbiology

authors： Georg RC,Stefani RM,Gomes SL

更新日期：2009-10-29 00:00:00

abstract：BACKGROUND:Bifidobacteria is one of the major gut commensal groups found in infants. Their colonization is commonly associated with beneficial effects to the host through mechanisms like niche occupation and nutrient competition against pathogenic bacteria. Iron is an essential element necessary for most microorganisms...

journal_title：BMC microbiology

authors： Vazquez-Gutierrez P,Lacroix C,Jaeggi T,Zeder C,Zimmerman MB,Chassard C

更新日期：2015-01-16 00:00:00

abstract：BACKGROUND:Establishing an optimal proportion of nitrifying microbial populations, including ammonia-oxidizing bacteria (AOB), nitrite-oxidizing bacteria (NOB), complete nitrite oxidizers (comammox) and ammonia-oxidizing archaea (AOA), is important for ensuring the efficiency of nitrification in water treatment systems...

journal_title：BMC microbiology

authors： Scarascia G,Cheng H,Harb M,Hong PY

更新日期：2017-04-04 00:00:00

abstract：BACKGROUND:Pseudomonas syringae is pathogenic to a large number of plant species. For host colonization and disease progression, strains of this bacterium utilize an array of type III-secreted effectors and other virulence factors, including small secreted molecules such as syringolin A, a peptide derivative that inhib...

journal_title：BMC microbiology

authors： Dudnik A,Dudler R

更新日期：2014-12-04 00:00:00

abstract：BACKGROUND:Pneumococcus is exposed to a variety of temperature and oxygen levels in the upper respiratory tract and as it invades the lung, tissues, and blood. We sought to determine the effect of environmental variability on growth in vitro and to assess variability between strains. We evaluated the effect of temperat...

journal_title：BMC microbiology

authors： Tóthpál A,Desobry K,Joshi SS,Wyllie AL,Weinberger DM

更新日期：2019-12-26 00:00:00

abstract：BACKGROUND:Wolbachia are the most widely spread endosymbiotic bacteria, present in a wide variety of insects and two families of nematodes. As of now, however, relatively little genomic data has been available. The Wolbachia symbiont can be parasitic, as described for many arthropod systems, an obligate mutualist, as i...

journal_title：BMC microbiology

authors： Lefoulon E,Clark T,Borveto F,Perriat-Sanguinet M,Moulia C,Slatko BE,Gavotte L

更新日期：2020-06-30 00:00:00

abstract：BACKGROUND:The resurgence of multi-drug resistant tuberculosis (MDR-TB) and HIV associated tuberculosis (TB) are of serious global concern. To contain this situation, new anti-tuberculosis drugs and reduced treatment regimens are imperative. Recently, a nitroimidazole, PA-824, has been shown to be active against both r...

journal_title：BMC microbiology

authors： Somasundaram S,Anand RS,Venkatesan P,Paramasivan CN

更新日期：2013-10-01 00:00:00