Exercise preconditioning and brain ischemic tolerance.

abstract：:Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are neurodegenerative diseases that overlap clinically, genetically, and pathologically. Dysregulation of fused in sarcoma (FUS) has been hypothesized to cause ALS and FTLD in gain-of-function and/or loss-of-function manners. However, the...

journal_title：Neuroscience

authors： Suzuki H,Matsuoka M

更新日期：2015-02-26 00:00:00

abstract：:Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor Fibroblast growth factor-inducible 14 (Fn14) are expressed in neurons. Here we demonstrate that TWEAK induces a dose-dependent increase in neuronal death and that this effect is independent of tumor necrosis factor alpha (TNF-α) and mediated...

journal_title：Neuroscience

authors： Haile WB,Echeverry R,Wu F,Guzman J,An J,Wu J,Yepes M

更新日期：2010-12-29 00:00:00

abstract：OBJECTIVE:To examine the efficiency of hydrogen-rich saline in the treatment of intensive noise-induced cochlear injury. MATERIALS AND METHODS:Forty guinea pigs were assigned to one of four groups: HS+NOISE (i.p. injection hydrogen-rich saline), NS+NOISE (i.p. injection normal saline), NOISE ALONE (noise control), and...

journal_title：Neuroscience

authors： Zhou Y,Zheng H,Ruan F,Chen X,Zheng G,Kang M,Zhang Q,Sun X

更新日期：2012-05-03 00:00:00

abstract：:In the ventral mesencephalon, two neurotrophic factors, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor, have been shown previously to have similar effects on the survival of dopaminergic neurons. Here, we compared the signaling mechanisms for brain-derived neurotrophic factor and gli...

journal_title：Neuroscience

authors： Feng L,Wang CY,Jiang H,Oho C,Dugich-Djordjevic M,Mei L,Lu B

更新日期：1999-01-01 00:00:00

abstract：:Investigation of rhythmic discharges may provide insights into integrative mechanisms underlying nervous system control of effectors. We have previously shown that, in CNS-intact, anesthetized rats, cutaneous sympathetic vasoconstrictor neurones innervating thermoregulatory circulations exhibit a robust rhythmicity in...

journal_title：Neuroscience

authors： Collins DR,Gilbey MP

更新日期：2003-01-01 00:00:00

abstract：:Inside-out patch recordings from rat acutely dissociated cerebral cortical neurons revealed time and voltage-dependent activity of a large-conductance calcium-activated potassium channel. Channel activity inactivated within minutes following a depolarizing voltage step, and was recovered from inactivation by membrane ...

journal_title：Neuroscience

authors： Smith MA,Ashford ML

更新日期：2000-01-01 00:00:00

abstract：:Altered gene expression mediated by calcium/calmodulin-dependent protein kinase II (CaMKII) and other intracellular signaling molecules plays an important role in activity-dependent neuroplasticity. We discovered that sustained depolarization induced by KCl, a commonly used paradigm for studying activity-dependent gen...

journal_title：Neuroscience

authors： Padmanabhan S,Prasad BM

更新日期：2009-09-29 00:00:00

abstract：:The identification of leptin and a range of novel anorectic and orexigenic peptides has focussed attention on the neural circuitry involved in the genesis of food intake and the reflex control of thermogenesis. Here, the neurotropic virus pseudorabies has been utilised in conjunction with the immunocytochemical locali...

journal_title：Neuroscience

authors： Oldfield BJ,Giles ME,Watson A,Anderson C,Colvill LM,McKinley MJ

更新日期：2002-01-01 00:00:00

abstract：:The goal of the present experiments was to examine the relationships of the zona incerta with two structures associated with visuomotor behavior, the superior colliculus and pretectum. The experiments were carried out in the cat, a species commonly used in studies of visuomotor integration, and utilized wheat germ agg...

journal_title：Neuroscience

authors： May PJ,Sun W,Hall WC

更新日期：1997-04-01 00:00:00

abstract：:Coping skills are essential in determining the outcomes of aversive life events. Our research was aimed to elucidate the molecular underpinnings of different coping styles in two inbred mouse strains, C57BL/6J and SWR/J. We compared the influence of a preceding stressor (0.5h of restraint) on behavioral and gene expre...

journal_title：Neuroscience

authors： Szklarczyk K,Korostynski M,Golda S,Piechota M,Ficek J,Przewlocki R

更新日期：2016-08-25 00:00:00

abstract：:Classic neurotransmitter phenotypes are generally predetermined and develop as a consequence of target-independent lineage decisions. A unique mode of target-dependent phenotype instruction is the acquisition of the cholinergic phenotype in the peripheral sympathetic nervous system. A body of work suggests that the sw...

journal_title：Neuroscience

authors： Schütz B,von Engelhardt J,Gördes M,Schäfer MK,Eiden LE,Monyer H,Weihe E

更新日期：2008-10-02 00:00:00

abstract：:Extensive studies have shown that a sports expert is superior to a sports novice in visually perceptual-cognitive processes of sports scene information, however the attentional and neural basis of it has not been thoroughly explored. The present study examined whether a sport expert has the attentional superiority on ...

journal_title：Neuroscience

authors： He M,Qi C,Lu Y,Song A,Hayat SZ,Xu X

更新日期：2018-05-21 00:00:00

abstract：:Intrinsic connectivity networks (ICNs) are composed of spatial components and time courses. The spatial components of ICNs were discovered with moderate-to-high reliability. So far as we know, few studies focused on the reliability of the temporal patterns for ICNs based their individual time courses. The goals of thi...

journal_title：Neuroscience

authors： Wang X,Jiao Y,Tang T,Wang H,Lu Z

更新日期：2013-12-19 00:00:00

abstract：:Emerging evidence suggests that brain aquaporins (AQP) play important roles for the dynamic regulation of brain water homeostasis and for the regulation of cerebrospinal fluid production. This review deals with the short- and long-term regulation of AQP4 and AQP9, both expressed in astrocytes, and of AQP1, expressed i...

journal_title：Neuroscience

authors： Gunnarson E,Zelenina M,Aperia A

更新日期：2004-01-01 00:00:00

abstract：:Neuroinflammation contributes to neuronal death in cerebral ischemia. Urolithin A (UA), a gut microbial metabolite of ellagic acid, has emerged as a potential anti-inflammatory agent. However, its roles and precise mechanisms in stroke remain unknown. Here we found that UA treatment ameliorated infarction, neurologica...

journal_title：Neuroscience

authors： Lin XH,Ye XJ,Li QF,Gong Z,Cao X,Li JH,Zhao ST,Sun XD,He XS,Xuan AG

更新日期：2020-11-10 00:00:00

abstract：:The blockade of serotoninergic receptors with methysergide or the activation of alpha(2)-adrenoceptors with moxonidine into the lateral parabrachial nucleus (LPBN) increases water and 0.3 M NaCl intake in rats treated with furosemide (FURO) combined with captopril (CAP). In the present study we investigated the effect...

journal_title：Neuroscience

authors： Gasparini S,de Luca LA Jr,Colombari DS,de Paula PM,Barbosa SP,Menani JV

更新日期：2009-12-01 00:00:00

abstract：:The dual effect of capsaicin on primary afferent neurons, excitation and stimulation of transmitter release, its dependence on extracellular calcium and its modulation by Ruthenium Red have been investigated in the rabbit ear. Injection of capsaicin into the central artery of the isolated perfused ear with intact neur...

journal_title：Neuroscience

authors： Amann R,Donnerer J,Lembeck F

更新日期：1989-01-01 00:00:00

abstract：:Diabetes mellitus-induced metabolic disturbances underlie the action of many systems including some higher functions of the brain such as learning and memory. Plenty of evidence supports the effects of probiotics on the function of many systems including the nervous system. Here we report the effect of probiotics trea...

journal_title：Neuroscience

authors： Davari S,Talaei SA,Alaei H,Salami M

更新日期：2013-06-14 00:00:00

abstract：:Prialt, a synthetic version of Ca(v)2.2 antagonist ω-conotoxin MVIIA derived from Conus magus, is the first clinically approved voltage-gated calcium channel blocker for refractory chronic pain. However, due to the narrow therapeutic window and considerable side effects associated with systemic dosing, Prialt is only ...

journal_title：Neuroscience

authors： Patel R,Rutten K,Valdor M,Schiene K,Wigge S,Schunk S,Damann N,Christoph T,Dickenson AH

更新日期：2015-06-25 00:00:00

abstract：:The effects of muscle fatigue are known to be altered in older adults, and age-related changes in the brain are likely to be a contributing factor. However, the neural mechanisms underlying these changes are not known. The aim of the current study was to use transcranial magnetic stimulation combined with electroencep...

journal_title：Neuroscience

authors： Opie GM,Otieno LA,Pourmajidian M,Semmler JG,Sidhu SK

更新日期：2020-01-15 00:00:00

abstract：:In the latero-anterior hypothalamus (LAH) increased glutamate and vasopressin (AVP) activity facilitate anabolic androgenic steroid (AAS)-induced offensive aggression. In addition, adolescent AAS treatment increases the strength of glutamate-mediated connections between the LAH and the brain nucleus of stria terminali...

journal_title：Neuroscience

authors： Carrillo M,Ricci LA,Melloni RH

更新日期：2011-06-30 00:00:00

abstract：:Ocular dominance has been extensively studied, often with the goal to understand neuroplasticity, which is a key characteristic within the critical period. Recent work on monocular deprivation, however, demonstrates residual neuroplasticity in the adult visual cortex. After deprivation of patterned inputs by monocular...

journal_title：Neuroscience

authors： Bai J,Dong X,He S,Bao M

更新日期：2017-06-03 00:00:00

abstract：:The visual word form area (VWFA) has been consistently identified as a crucial structure in visual word processing. Nevertheless, it is controversial whether the VWFA represents external visual information (e.g., case information) of visual words. To address that question, we functionally localized VWFA at the group l...

journal_title：Neuroscience

authors： Lu C,Li H,Fu R,Qu J,Yue Q,Mei L

更新日期：2021-01-01 00:00:00

abstract：:Three closely-linked clusters of protocadherin (Pcdh) genes (alpha, beta, and gamma) encoding more than 50 distinct mRNAs have been identified in humans and mice, and proposed to play important roles in neuronal connectivity in the CNS. The human and mouse Pcdh alpha and gamma clusters each span a region of about 300 ...

journal_title：Neuroscience

authors： Zou C,Huang W,Ying G,Wu Q

更新日期：2007-01-19 00:00:00

abstract：:Brainstem projections to hypoglossal motoneurons innervating the intrinsic and extrinsic muscles of the tongue were determined using the transneuronal transfer of Herpes simplex virus-1. Injections of Herpes simplex virus-1 into the intrinsic muscles of the anterior tongue, the geniohyoid and styloglossus muscles each...

journal_title：Neuroscience

authors： Travers JB,Montgomery N,Sheridan J

更新日期：1995-10-01 00:00:00

abstract：:The present study was designed to clarify an intensity-dependent effect of prenatal stress on the morphological development of hippocampal neurons in rats. In addition, the involvement of receptors for glucocorticoids, i.e. mineralocorticoid receptors and glucocorticoid receptors, in stress-induced changes in the morp...

journal_title：Neuroscience

authors： Fujioka A,Fujioka T,Ishida Y,Maekawa T,Nakamura S

更新日期：2006-08-25 00:00:00

abstract：:Histamine, a putative neuromodulator and neurotransmitter, can depolarize supraoptic neurons and enhance depolarizing afterpotentials that play a key role in determining the excitability of these neurons. This study investigated intracellular signal transduction involved in histamine-induced enhancement of depolarizin...

journal_title：Neuroscience

authors： Li Z,Miyata S,Hatton GI

更新日期：1999-01-01 00:00:00

abstract：:p53 and parkin are involved in mitochondrial quality control. The present study aimed to characterize the functional significance of parkin/p53 in the development of mitochondrial dysfunction and the pathophysiology of neuropathic pain in type I diabetes. Type I diabetes was induced in mice (N = 170) using streptozoto...

journal_title：Neuroscience

authors： Yamashita A,Matsuoka Y,Matsuda M,Kawai K,Sawa T,Amaya F

更新日期：2019-09-15 00:00:00

abstract：:High resolution immunogold cytochemistry was used to investigate the subcellular distribution of protein kinase C gamma and delta in Purkinje cells of the rat cerebellum. Postembedding incubation with an antibody raised to a peptide sequence near the C-terminus of protein kinase C gamma resulted in strong labelling al...

journal_title：Neuroscience

authors： Cardell M,Landsend AS,Eidet J,Wieloch T,Blackstad TW,Ottersen OP

更新日期：1998-02-01 00:00:00

abstract：:We assessed the effect of 3h of environmental enrichment (EE) exposure per day started at different ages (3 and 18months old) on the performance in a spatial memory task and on brain regions involved in the spatial learning (SPL) process using the principal component analysis (PCA). The animals were tested in the four...

journal_title：Neuroscience

authors： Sampedro-Piquero P,Begega A,Zancada-Menendez C,Cuesta M,Arias JL

更新日期：2013-09-17 00:00:00