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Internal reflectivity of filtering blebs versus intraocular pressure in patients with recent trabeculectomy.

Abstract：

PURPOSE:The authors conducted a morphology analysis of filtering blebs with anterior segment optical coherence tomography (AS-OCT) in patients shortly after trabeculectomy to find further criteria for success or failure of a filtering bleb. METHODS:Thirty-seven patients (43 eyes) who had recently (<2 years) undergone trabeculectomy were measured 1 to 4 times with AS-OCT. In contrast to ultrasound biomicroscopy, AS-OCT eliminates the need for a water bath in contact with the globe. This is of particular value in a study of morphologic parameters that may be altered by contact and in the postoperative period when concerns of infection are paramount. In this study, the internal reflectivity of the fluid-filled cavity of the filtering bleb was compared with the intraocular pressure (IOP). RESULTS:Mean age of the patients was 69.5 years (range, 27-84 years). Average preoperative IOP of the 43 eyes was 20.6 mm Hg (range, 10-42 mm Hg), average postoperative IOP at the time of AS-OCT measurement was 10.6 mm Hg (range, 2-40 mm Hg), and mean IOP reduction was 10.0 mm Hg (48.5%). Internal reflectivity of the fluid-filled cavity of the filtering bleb correlated very well to the IOP (R(2) = 0.3762, n = 61, P < 0.0001). CONCLUSIONS:AS-OCT is a promising tool with which to analyze the morphology of the filtering bleb after trabeculectomy. A highly significant correlation between the internal reflectivity of the fluid-filled cavity of the filtering bleb and the IOP could be shown that may have future impact in evaluating the postoperative success or failure of filtering blebs.

journal_name

Invest Ophthalmol Vis Sci

journal_title

Investigative ophthalmology & visual science

authors

Pfenninger L,Schneider F,Funk J

doi

10.1167/iovs.10-5520

subject

Has Abstract

pub_date

2011-04-14 00:00:00

pages

2450-5

issue

5

eissn

0146-0404

issn

1552-5783

pii

iovs.10-5520

journal_volume

52

pub_type

杂志文章

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