Duration and magnitude of extracellular signal-regulated protein kinase phosphorylation determine adipogenesis or osteogenesis in human bone marrow-derived stem cells.

abstract：PURPOSE:Physicians and oncology nurses must continue to update their knowledge on treatment and treatment-related side effects, while searching for effective methods to prevent or manage side effects. The objective of our study was to describe the incidence and response to treatment of the hand-foot syndrome (HFS) and ...

journal_title：Yonsei medical journal

authors： Son HS,Lee WY,Lee WS,Yun SH,Chun HK

更新日期：2009-12-31 00:00:00

abstract：:The clinical benefits of intravesical electrical stimulation (IVES) in patients with increased residual urine or reduced bladder capacity have been reported. However, studies on the underlying mechanism of IVES has been limited to the Adelta afferent and parasympathetic neurons. This study investigated the changes in ...

journal_title：Yonsei medical journal

authors： Hong CH,Kim JH,Noh JY,Gil YC,Lee HY,Lee WH,Han SW

更新日期：2002-10-01 00:00:00

abstract：PURPOSE:To explore the effect of bi-parametric MRI-ultrasound (MR/US) fusion prostate biopsy on the detection of overall cancer and significant prostate cancer (sPCa). MATERIALS AND METHODS:We examined 140 patients with suspected prostate cancer lesions on MRI from August 2016 to March 2018. All patients had undergone...

journal_title：Yonsei medical journal

authors： Kim YJ,Huh JS,Park KK

更新日期：2019-04-01 00:00:00

abstract：PURPOSE:We conducted a multi-center randomized double-blind study to determine the effects of 6-month therapy with sulodexide on urinary protein excretion in patients with idiopathic Immunoglobulin A (IgA) nephropathy. MATERIALS AND METHODS:A total of seventy-seven patients participated in the study. They were randoml...

journal_title：Yonsei medical journal

authors： Bang K,Chin HJ,Chae DW,Joo KW,Kim YS,Kim S,Ju KD,Kim H,Ahn C,Oh KH

更新日期：2011-07-01 00:00:00

abstract：:We have investigated the potential usefulness of stereoscopic viewing of optic disc photographs in marking the disc margin in computerized analysis with the Rodenstock Analyzer in 48 eyes of 26 patients with ocular hypertension or primary open-angle glaucoma. Marking of the disc margin without Method 1) and with the a...

journal_title：Yonsei medical journal

authors： Hong YJ,Shin DH

更新日期：1990-12-01 00:00:00

abstract：:In most cases, while schwannoma is sporadically manifested as a single benign neoplasm, the presence of multiple schwannomas in one patient is usually indicative of neurofibromatosis 2. However, several recent reports have suggested that schwannomatosis itself may also be a distinct clinical entity. This study examine...

journal_title：Yonsei medical journal

authors： Ahn JY,Kwon SO,Shin MS,Shim JY,Kim OJ

更新日期：2002-02-01 00:00:00

abstract：:This study was undertaken to evaluate the clinical usefulness of operative laparoscopy in treatment of benign ovarian cysts. A retrospective study was carried on 468 operative laparoscopy cases performed from September 1995 to September 1998 at Yonsei University College of Medicine, Department of Obstetrics and Gyneco...

journal_title：Yonsei medical journal

authors： Park KH,Chung JE,Kim JY,Lee BS

更新日期：1999-12-01 00:00:00

abstract：:Rett's syndrome(RS) is a progressive neurodegenerative disorder characterized by exclusive occurrence in females, autistic behavior, dementia, gait ataxia, loss of purposeful use of the hands with stereotypic hand movement, and seizures. Initially RS was considered to be very rare; however, recent reports suggest that...

journal_title：Yonsei medical journal

authors： Choi YC,Lee BI,Huh K,Kim GW

更新日期：1991-06-01 00:00:00

abstract：:For the present, to determine growth hormone(GH) deficiency in patients with short stature, many provocative tests using various pharmacological agents such as glucagon, insulin, clonidine, arginine, growth hormone releasing factor, etc. should be done. These are not only complicated but are also misleading in some pa...

journal_title：Yonsei medical journal

authors： Park MS,Kim DH

更新日期：1989-12-01 00:00:00

abstract：PURPOSE:Evidence on the contribution of genes to the hereditary predisposition to pulmonary arterial hypertension (PAH) is limited. MATERIALS AND METHODS:In this study, we hypothesized that single nucleotide variants in vascular endothelial growth factor (VEGF) gene may alter gene function and expression and may be as...

journal_title：Yonsei medical journal

authors： Zhuo Y,Zeng Q,Zhang P,Li G,Xie Q,Cheng Y

更新日期：2017-03-01 00:00:00

abstract：PURPOSE:Lacunar stroke, in the context of small vessel disease, is a type of cerebral infarction caused by occlusion of a penetrating artery. Pulsatility index (PI) is an easily measurable parameter in Transcranial Doppler ultrasound (TCD) study. PI reflects distal cerebral vascular resistance and has been interpreted ...

journal_title：Yonsei medical journal

authors： Kim Y,Lee H,An SA,Yim B,Kim J,Kim OJ,Kim WC,Kim HS,Oh SH,Kim J

更新日期：2016-07-01 00:00:00

abstract：:Peripheral nerve injury frequently leads to neuropathic pain like hyperalgesia, spontaneous pain, mechanical allodynia, thermal allodynia. It is uncertain where the neuropathic pain originates and how it is transmitted to the central nervous system. This study was performed in order to determine which peripheral compo...

journal_title：Yonsei medical journal

authors： Won R,Lee BH,Park S,Kim SH,Park YG,Chung SS

更新日期：2000-06-01 00:00:00

abstract：PURPOSE:Hypoxemia during one-lung ventilation (OLV) remains a serious problem, particularly in the supine position. We investigated the effects of alveolar recruitment (AR) and positive end-expiratory pressure (PEEP) on oxygenation during OLV in the supine position. MATERIALS AND METHODS:Ninety-nine patients were rand...

journal_title：Yonsei medical journal

authors： Choi YS,Bae MK,Kim SH,Park JE,Kim SY,Oh YJ

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:Although follicular thyroid cancer (FTC) has a relatively fair prognosis, distant metastasis sometimes results in poor prognosis and survival. There is little understanding of the mechanisms contributing to the aggressiveness potential of thyroid cancer. We showed that hypoxia inducible factor-1α (HIF-1α) induc...

journal_title：Yonsei medical journal

authors： Yang YJ,Na HJ,Suh MJ,Ban MJ,Byeon HK,Kim WS,Kim JW,Choi EC,Kwon HJ,Chang JW,Koh YW

更新日期：2015-11-01 00:00:00

abstract：PURPOSE:This study investigated whether hormones and pain perception are associated with exam anxiety, and also whether exam anxiety is affected by seasonal differences in testosterone and cortisol levels. MATERIALS AND METHODS:Forty-six healthy males were recruited from a medical college. Anxiety was induced by havin...

journal_title：Yonsei medical journal

authors： Choi JC,Lee JH,Choi E,Chung MI,Seo SM,Lim HK

更新日期：2014-01-01 00:00:00

abstract：:This study sought to determine the outcomes of posterior lumbar interbody fusion (PLIF), via a unilateral approach, in selected patients who presented with unilateral leg pain and segmental instability of the lumbar spine. Patients with a single level of a herniated disc disease in the lumbar spine, unilateral leg pai...

journal_title：Yonsei medical journal

authors： Shin HC,Yi S,Kim KN,Kim SH,Yoon DH

更新日期：2006-06-30 00:00:00

abstract：PURPOSE:To evaluate reliability of Fourier-domain optical coherence tomography (OCT) (RTVue), time-domain OCT (Visante), and slit-lamp adapted ultrasonic pachymetry (SL-US) in the measurement of central corneal thickness (CCT). MATERIALS AND METHODS:Thirty healthy volunteers visited our clinic 3 times and fifty eyes w...

journal_title：Yonsei medical journal

authors： Hong JP,Nam SM,Kim TI,Seo KY,Lee SY,Meduri A,Kim EK

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:The diagnosis of pulmonary fungal infections is challenging due to the difficulty of obtaining sufficient specimens. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) needle rinse fluid has become an emerging diagnostic material. This study evaluated the role of routine fungal culture...

journal_title：Yonsei medical journal

authors： Ko RE,Jeong BH,Huh HJ,Lee NY,Yoo H,Jhun BW,Han J,Lee K,Kim H,Kwon OJ,Um SW

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:Patients with chronic kidney disease frequently show cognitive dysfunction. The association of depression and cognitive function is not well known in maintenance dialysis patients. We evaluated cognitive impairment and depression, as well as their relationship in regards to methods of dialysis, maintenance hemo...

journal_title：Yonsei medical journal

authors： Jung S,Lee YK,Choi SR,Hwang SH,Noh JW

更新日期：2013-11-01 00:00:00

abstract：:To determine whether the dysfunction of p53 protein, caused either by the mutation of p53 gene itself or by the human papillomavirus (HPVs) is involved in the development of cervical cancers and to find out the status of p53 tumor suppressor gene in HPV positive or negative cancers, we analyzed 64 cases of primary cer...

journal_title：Yonsei medical journal

authors： Kim KH,Kim YS

更新日期：1995-11-01 00:00:00

abstract：PURPOSE:Several analgesic techniques are available for pain management after a major operation. MATERIALS AND METHODS:From December 2005 to February 2006, a prospective, double-blind study was performed involving 90 patients who had undergone a total knee arthroplasty. Patients were randomly divided into three equal g...

journal_title：Yonsei medical journal

authors： Han CD,Lee DH,Yang IH

更新日期：2007-04-30 00:00:00

abstract：:A giant esophageal liposarcoma showing rapid growth over 7 months is presented in 56-year-old man. It originated from the pharyngo-esophageal junction with a short stalk, and extended downward to the distal esophagus. A barium swallow study showed a large, sausage-like intraluminal mass in the dilated esophagus. CT an...

journal_title：Yonsei medical journal

authors： Chung JJ,Kim MJ,Kim JH,Lee JT,Yoo HS,Kim KW

更新日期：2003-08-30 00:00:00

abstract：:The clinicopathological features of 9 cases of Kimura's disease and 5 cases of epithelioid hemangioma(EH) were reviewed. Patients with Kimura's disease presented with multiple or solitary large tumors occurring in the thigh, arms as well as parotid gland. Histologically, the lesions were characterized by numerous lymp...

journal_title：Yonsei medical journal

authors： Ahn HJ,Lee KG

更新日期：1990-09-01 00:00:00

abstract：:Among chlorophyll derivatives (CpD-A, -B, -C, and -D) extracted from silk worm (Bombyx mori) excretas, CpD-A was extensively studied to clarify its role as a "photosensitizer" for photodynamic therapy (PDT) of tumors in vitro. It was found that CpD-A was photoreactive both in itself and also in its cell bound forms. T...

journal_title：Yonsei medical journal

authors： Lee WY,Park JH,Kim BS,Han MJ,Hahn BS

更新日期：1990-09-01 00:00:00

abstract：PURPOSE:Growing evidence suggests that hypoadiponectinemia may play a significant role in the development of metabolic syndrome (MetS). Therefore, the relationships between serum adiponectin with MetS and components of MetS were investigated in non-diabetic samples of drawn from the Koreans general population. MATERIA...

journal_title：Yonsei medical journal

authors： Koh SB,Yoon J,Kim JY,Yoo BS,Lee SH,Park JK,Choe KH

更新日期：2011-03-01 00:00:00

abstract：:Silicosis had been considered for decades as an illness with manifestations of lung fibrosis due to inhalation of overconcentrated SiO₂ dust. To the best of our knowledge, studies have yet to report SiO₂ deposits in any other tissues and organs. In the present case, while performing bilateral artificial total hip arth...

journal_title：Yonsei medical journal

authors： Xu M,Qing M,Peng D

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:Alpha-fetoprotein (AFP) is a prognostic marker for hepatocellular carcinoma (HCC). We investigated the prognostic value of AFP levels in patients who achieved complete response (CR) to transarterial chemoembolization (TACE) for HCC. MATERIALS AND METHODS:Between 2005 and 2018, 890 patients with HCC who achieve...

journal_title：Yonsei medical journal

authors： Lee JS,Chon YE,Kim BK,Park JY,Kim DY,Ahn SH,Han KH,Kang W,Choi MS,Gwak GY,Paik YH,Lee JH,Koh KC,Paik SW,Kim HY,Kim TH,Yoo K,Ha Y,Kim MN,Lee JH,Hwang SG,Kim SS,Cho HJ,Cheong JY,Cho SW,Park SH,Heo NY,H

更新日期：2021-01-01 00:00:00

abstract：:Kinematically aligned total knee arthroplasty (TKA) is a new alignment technique. Kinematic alignment corrects arthritic deformity to the patient's constitutional alignment in order to position the femoral and tibial components, as well as to restore the knee's natural tibial-femoral articular surface, alignment, and ...

journal_title：Yonsei medical journal

authors： Kim KK,Howell SM,Won YY

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:The treatment of a clinically node-positive (cN+) neck is important in the management of oral cavity squamous cell carcinoma (OSCC). However, the extent of neck dissection (ND) remains controversial. The purpose of our study was to evaluate whether level IV or V can be excluded in therapeutic ND for cN+ OSCC pa...

journal_title：Yonsei medical journal

authors： Shin YS,Koh YW,Kim SH,Choi EC

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:The association between liver enzymes and death from external causes has not been examined. We investigated the association between serum aminotransferase levels and external-cause mortality in a large prospective cohort study. MATERIALS AND METHODS:A total of 142,322 subjects of 35-59 years of age who complet...

journal_title：Yonsei medical journal

authors： Sohn J,Kang DR,Kim HC,Cho J,Choi YJ,Kim C,Suh I

更新日期：2015-11-01 00:00:00