Abstract:
PURPOSE:To explore the effect of bi-parametric MRI-ultrasound (MR/US) fusion prostate biopsy on the detection of overall cancer and significant prostate cancer (sPCa). MATERIALS AND METHODS:We examined 140 patients with suspected prostate cancer lesions on MRI from August 2016 to March 2018. All patients had undergone 3T pre-biopsy bi-parametric (T2 weighted and diffusion-weighted) prostate MRI (bpMRI), and their MRI images were evaluated with Prostate Imaging Reporting and Data System (PI-RADS) version 2.0. MR/US fusion targeted prostate biopsy was performed for lesions with a PI-RADS score ≥3 before systemic biopsy. The results of targeted and systemic biopsy were evaluated in regards to detection rate according to PI-RADS score. RESULTS:Of the patients (mean age=67.2 years, mean prostate-specific antigen level=8.1 ng/mL), 66 (47.1%) and 37 (26.4%) patients were diagnosed with cancer and significant prostate cancer, respectively. The rate of positive targeted biopsy increased with higher PI-RADS score (3: 40.4%, 4: 56.7%, 5: 90.0%). The proportion of significant prostate cancer among positive target lesions was 65.3% (32/49). CONCLUSION:bpMRI is a feasible tool with which to identify sPCa. MR/US fusion biopsy, rather than systemic biopsy, can help identify sPCa. We recommend using supplemental tools to increase prostate cancer detection in patients with PI-RADS 3 lesions.
journal_name
Yonsei Med Jjournal_title
Yonsei medical journalauthors
Kim YJ,Huh JS,Park KKdoi
10.3349/ymj.2019.60.4.346subject
Has Abstractpub_date
2019-04-01 00:00:00pages
346-351issue
4eissn
0513-5796issn
1976-2437pii
60.346journal_volume
60pub_type
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journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2012.53.6.1113
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pub_type: 杂志文章,评审
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journal_title:Yonsei medical journal
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doi:10.3349/ymj.2017.58.4.770
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journal_title:Yonsei medical journal
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doi:10.3349/ymj.1993.34.2.117
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journal_title:Yonsei medical journal
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journal_title:Yonsei medical journal
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journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.1999.40.3.207
更新日期:1999-06-01 00:00:00
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journal_title:Yonsei medical journal
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journal_title:Yonsei medical journal
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pub_type: 杂志文章
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journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2013.54.2.445
更新日期:2013-03-01 00:00:00