Abstract:
CONTEXT:Joint trauma is a risk factor for osteoarthritis (OA), which is becoming an increasingly important orthopedic concern for athletes and nonathletes alike. For advances in OA prevention, diagnosis, and treatment to occur, a greater understanding of the biochemical environment of the affected joint is needed. OBJECTIVE:To demonstrate the potential of a biochemical technique to enhance our understanding of and diagnostic capabilities for osteoarthritis. DESIGN:Cross-sectional. SETTING:Outpatient orthopedic practice. PARTICIPANTS:8 subjects: 4 OA-knee participants (65 ± 6 y of age) and 4 normal-knee participants (54 ± 10 y) with no history of knee OA based on bilateral standing radiographs. INTERVENTION:The independent variable was group (OA knee, normal knee). MAIN OUTCOME MEASURES:16 knee synovial-protein concentrations categorized as follows: 4 as pro-inflammatory, or catabolic, cytokines; 5 as anti-inflammatory, or protective, cytokines; 3 as catabolic enzymes; 2 as tissue inhibitors of metalloproteinases [TIMPs]; and 2 as adipokines. RESULTS:Two anti-inflammatory cytokines (interleukin [IL]-13 and osteoprotegerin) and a pro-inflammatory cytokine (IL-1β) were significantly lower in the OA knees. Two catabolic enzymes (matrix metalloproteinase [MMP]-2 and MMP-3) were significantly elevated in OA knees. TIMP-2, an inhibitor of MMPs, was significantly elevated in OA knees. CONCLUSIONS:Six of the 16 synovial-fluid proteins were significantly different between OA knees and normal knees in this study. Future research using a similar multiplex ELISA approach or other proteomic techniques may enable researchers and clinicians to develop more accurate biochemical profiles of synovial fluid to help diagnose OA, identify subsets of OA or individual characteristics, guide clinical decisions, and identify patients at risk for OA after knee injury.
journal_name
J Sport Rehabiljournal_title
Journal of sport rehabilitationauthors
Driban JB,Balasubramanian E,Amin M,Sitler MR,Ziskin MC,Barbe MFdoi
10.1123/jsr.19.4.411subject
Has Abstractpub_date
2010-11-01 00:00:00pages
411-21issue
4eissn
1056-6716issn
1543-3072journal_volume
19pub_type
杂志文章abstract:CONTEXT:A multidisciplinary approach is one of the many forms of professional practice that can be utilized by sports medicine professionals to provide care to injured athletes. While this approach has been empirically supported in the health care domain, studies supporting its utilization in the sport injury rehabilit...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.2020-0094
更新日期:2020-11-25 00:00:00
abstract::Context: Recent data on exertional heat illness (EHI) in high school sports are limited yet warranted to identify specific settings with the highest risk of EHI. Objective: To describe the epidemiology of EHI in high school sports during the 2012/2013-2016/2017 academic years. Design: ...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.2018-0364
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVES:We report our observations on one soldier with abnormal hyperthermia during exercise in the heat compared with prior exercise and following acute local (non-febrile) infection. Also, we report on 994 heat stroke hospitalizations in the U.S. Army. It is known that prior infection is a risk factor for heat ill...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.16.3.238
更新日期:2007-08-01 00:00:00
abstract::Clinical Scenario: Mild traumatic brain injury, or concussion, has been associated with physical, cognitive, and emotional sequelae. Little is understood in regard to many characteristics, such as anxiety, and their effect on post-concussion symptoms. CLINICAL QUESTION:Is state anxiety, trait anxiety, or anxiety sens...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.2016-0122
更新日期:2017-11-01 00:00:00
abstract:CONTEXT:Soft tissue restrictions have been linked to poor flexibility and decreased range of motion (ROM). To decrease the soft tissue restrictions and ultimately increase ROM/flexibility, myofascial release techniques, such as foam rolling (FR) and instrument-assisted soft tissue mobilization (IASTM), have been used. ...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.2018-0494
更新日期:2020-07-23 00:00:00
abstract::Clinical Scenario: The anterior cruciate ligament (ACL) injury is a common knee injury within varying athletic levels. Clinical diagnostic tests and magnetic resonance imaging (MRI) are two methods of evaluating ACL injuries. Clinical Question: Are clinical diagnostic tests as accurate as MRI when diagnosing ACL tears...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章,评审
doi:10.1123/jsr.2016-0188
更新日期:2018-11-01 00:00:00
abstract:CONTEXT:Patients with somatosensory deficits have been found to rely more on visual feedback for postural control. However, current balance tests may be limited in identifying increased visual dependence (sensory reweighting to the visual system), as options are typically limited to eyes open or closed conditions with ...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.2017-0035
更新日期:2017-09-01 00:00:00
abstract:CONTEXT:Sensorimotor, proprioceptive, and neuromuscular programs are critical for the successful rehabilitation of injured athletes, and these decrease reinjury rates. OBJECTIVE:To investigate the effects of an unexpected disturbance program (UDP) on balance and unilateral strength metrics in athletes with unilateral ...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.2019-0265
更新日期:2020-02-05 00:00:00
abstract:CONTEXT:Spinal-reflexive and corticomotor excitability may have a critical role in altering muscle function needed to stabilize the ankle in people with chronic ankle instability (CAI). OBJECTIVE:To determine the association between self-reported disability and both spinal-reflexive and corticomotor excitability in pe...
journal_title:Journal of sport rehabilitation
pub_type: 临床试验,杂志文章
doi:10-1123/jsr.2014-0282
更新日期:2016-05-01 00:00:00
abstract::It is estimated that approximately 350,000 individuals undergo anterior cruciate ligament (ACL) reconstruction surgery in each year in the US. Although ACL-reconstruction surgery and postoperative rehabilitation are successfully completed, deficits in postural control remain prevalent in ACL-reconstructed individuals....
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章,评审
doi:10-1123/jsr.2014-0226
更新日期:2016-05-01 00:00:00
abstract:CONTEXT:Despite prior studies that have addressed the recovery effects of cold-water immersion (CWI) in different sports, there is a lack of knowledge about longitudinal studies across a full season of competition assessing these effects. OBJECTIVE:To analyze the CWI effects, as a muscle recovery strategy, in professi...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.2018-0301
更新日期:2020-03-01 00:00:00
abstract::Clinical Scenario: Health care clinicians are encouraged to practice according to the best available evidence for the purpose of improving patient outcomes. Clinical practice guidelines are one form of evidence that has been developed to enhance the care that patients receive for particular conditions. Low back pain i...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章,评审
doi:10.1123/jsr.2015-0185
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:To determine if there is any benefit to static stretching after performing a dynamic warm-up in the prevention of injury in high school soccer athletes. DESIGN:Prospective cluster randomized nonblinded study. SETTING:12 high schools with varsity and junior varsity boys' soccer teams (24 soccer teams) across...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1123/jsr.2013-0114
更新日期:2015-08-01 00:00:00
abstract:CONTEXT:Blood flow restriction research has focused on muscular strength and hypertrophy. Limited data have been reported about the blood flow restriction effect on the tendon. OBJECTIVE:To analyze and compare the time course of recovery in Achilles tendon thickness after a single bout of low-intensity resistance trai...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.2019-0403
更新日期:2020-07-27 00:00:00
abstract:CLINICAL SCENARIO:Hamstring tightness is common among physically active individuals. In addition to limiting range of motion and increasing the risk of muscle strain, hamstring tightness contributes to a variety of orthopedic conditions. Therefore, clinicians continue to identify effective methods to increase flexibili...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章,评审
doi:10.1123/JSR.2013-0059
更新日期:2015-02-01 00:00:00
abstract:CONTEXT:Although body cooling has both performance and safety benefits, knowledge on optimizing cooling during specific sport competition is limited. OBJECTIVES:To identify when, during sport competition, it is optimal for body cooling and to identify optimal body-cooling modalities to enhance safety and maximize spor...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章,评审
doi:10.1123/jsr.2015-0008
更新日期:2016-12-01 00:00:00
abstract:CONTEXT:Female volleyball players are more predisposed to anterior cruciate ligament injury in comparison with their male counterparts. Recent research on anterior cruciate ligament injury prevention strategies has shown the positive results of adopting the external focus (EF) of attention in sports. OBJECTIVE:To dete...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.2018-0163
更新日期:2020-01-01 00:00:00
abstract:CONTEXT:Functional movement screening (FMS) has been gaining popularity in the fields of sports medicine and performance. Currently, limited research has examined whether FMS screening that identifies low FMS scores is attributed primarily to limits in range of motion (ROM). OBJECTIVE:To compare scores from the FMS hu...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.2015-0070
更新日期:2017-01-01 00:00:00
abstract:CONTEXT:Pulse rate is commonly measured manually or with commercial wrist or belt monitors. More recently, pulse-rate monitoring has become convenient with the use of mobile technology that allows monitoring through a smartphone camera. This optical technology offers many benefits, although the clinimetric properties h...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.2013-0145
更新日期:2015-05-01 00:00:00
abstract:CONTEXT:Though previous research has focused on examining the effects of concussion history using a dual-task paradigm, the influence of factors like symptoms (unrelated to concussion), gender, and type of sport on gait in college athletes is unknown. OBJECTIVE:To examine the effect of concussion history, symptoms, ge...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.2019-0331
更新日期:2021-01-08 00:00:00
abstract:CONTEXT:Clinically, it has been suggested that increased activation of intrinsic foot muscles may alter the demand of extrinsic muscle activity surrounding the ankle joint in patients with stage II posterior tibial tendon dysfunction. However, there is limited empirical evidence supporting this notion. OBJECTIVE:The p...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.2019-0211
更新日期:2020-03-31 00:00:00
abstract:STUDY DESIGN:Randomized controlled trial. OBJECTIVES:The aim of this study was to determine the effects of dry needling on hamstring extensibility and functional performance tests among asymptomatic individuals with hamstring muscle tightness. BACKGROUND:Dry needling has been shown to increase range of motion in the ...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1123/jsr.2016-0095
更新日期:2017-11-01 00:00:00
abstract::Clinical Scenario: Increasing hamstring flexibility through clinical stretching interventions may be an effective means to prevent hamstring injuries. However the most effective method to increase hamstring flexibility has yet to be determined. CLINICAL QUESTION:For a healthy individual, are proprioceptive neuromuscu...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.2016-0003
更新日期:2017-11-01 00:00:00
abstract::Clinical Scenario: Many people with lower quarter musculoskeletal dysfunction present with muscle weakness. Strength training hypertrophies muscle and increases strength, but often requires periods over 6 weeks, which can exceed the episode of care. Weakness can persist despite muscle hypertrophy, particularly in the ...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.2019-0372
更新日期:2020-06-05 00:00:00
abstract:CONTEXT:A normal breathing pattern while performing the abdominal-hollowing (AH) maneuver or spinal-stabilization exercise is essential for the success of rehabilitation programs and exercises. In previous studies, subjects were given standardized instructions to control the influence of respiration during the AH maneu...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.2012-0059
更新日期:2014-02-01 00:00:00
abstract::Health-related quality of life (HRQOL) is a broad, multidimensional concept that refers to a synthesis of several health domains including the physical, psychological, and social domains, all of which are affected by individual experiences, expectations, beliefs, and perceptions. HRQOL also shares a well-established c...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.20.1.17
更新日期:2011-02-01 00:00:00
abstract::Context: Knee abduction angle (KAA), as measured by 3-dimensional marker-based motion capture systems during jump-landing tasks, has been correlated with an elevated risk of anterior cruciate ligament injury in females. Due to the high cost and inefficiency of KAA measurement with marker-based motion capture, surrogat...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.2018-0017
更新日期:2019-05-01 00:00:00
abstract:CONTEXT:There are contradictory data on optimal muscle-activation strategies for restoring shoulder stability. Further investigation of neuromuscular-control strategies for glenohumeral-joint stability will guide clinicians in decisions regarding appropriate rehabilitation exercises. OBJECTIVES:To determine whether su...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.20.4.471
更新日期:2011-11-01 00:00:00
abstract:CONTEXT:Scapular bracing can correct scapular kinematics and restore normal scapular-muscle activity. However, there is little evidence to support the beneficial effects of a figure-8 strap, a type of scapular bracing, on muscle length, scapular alignment, and muscle activity during arm-lifting exercise. OBJECTIVE:To ...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.2015-0002
更新日期:2016-08-01 00:00:00
abstract:CONTEXT:Within each hamstring muscle, there are segments with separate nerve innervation. However, a better understanding of activation levels within these regions during resistance exercise could lead to region-specific training for improved performance and injury prevention. OBJECTIVE:To compare muscle activation le...
journal_title:Journal of sport rehabilitation
pub_type: 杂志文章
doi:10.1123/jsr.2019-0118
更新日期:2019-09-24 00:00:00