Abstract:
:To understand the genetic mechanisms leading to phenotypic differentiation, it is important to identify genomic regions under selection. We scanned the genome of two chicken lines from a single trait selection experiment, where 50 generations of selection have resulted in a 9-fold difference in body weight. Analyses of nearly 60,000 SNP markers showed that the effects of selection on the genome are dramatic. The lines were fixed for alternative alleles in more than 50 regions as a result of selection. Another 10 regions displayed strong evidence for ongoing differentiation during the last 10 generations. Many more regions across the genome showed large differences in allele frequency between the lines, indicating that the phenotypic evolution in the lines in 50 generations is the result of an exploitation of standing genetic variation at 100s of loci across the genome.
journal_name
PLoS Genetjournal_title
PLoS geneticsauthors
Johansson AM,Pettersson ME,Siegel PB,Carlborg Odoi
10.1371/journal.pgen.1001188subject
Has Abstractpub_date
2010-11-04 00:00:00pages
e1001188issue
11eissn
1553-7390issn
1553-7404journal_volume
6pub_type
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