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The urgency of surgical decompression in acute central cord injuries with spondylosis and without instability.

Abstract：

STUDY DESIGN:Systematic review, ambispective analysis of observational data. OBJECTIVE:To make recommendations as to whether or not urgent surgical decompression is ever indicated as the optimal treatment for enhancing neurologic recovery in a patient with acute central cord injury without fracture or instability. SUMMARY OF BACKGROUND DATA:There are currently no standards regarding the role and timing of decompression in acute traumatic central cord syndrome. In the setting of TCCS without spinal column instability, much controversy exists. METHODS:We have performed a thorough literature search based on the following question: "Is there a role for urgent (within 24 hours from injury to surgery) surgical decompression in acute central cord syndrome without fracture or instability specifically to enhance neurologic recovery?" Data including patient demographics, mechanism of injury, comorbidities, neurologic status, and surgical treatment was analyzed from a multicenter STSG observational database. Outcome measured included ASIA Motor Score, ASIA Grade, Functional Independence Measure (FIM) Score, SF-36, Sphincter Disturbance, and Ambulatory status. Measures were recorded on admission, discharge, 6 months and 1 year. RESULTS:At 12-month follow-up, early surgery resulted in a 6.31 point greater improvement in total motor score than did the late surgery group, with a P = 0.0358. At 6-month follow-up, early surgery result in higher chance of improvement in ASIA Grade than late surgery, with an odds ratio = 3.39, while at 12-month follow-up early surgery resulted in a higher chance of improvement in ASIA Grade, with an odds ratio of 2.81. Patients who were operated on within 24 hours had 7.79 U more improvement in FIM Total Score than late surgery at 6 month follow-up, with P = 0.0474. CONCLUSION:The consensus of experts following review of relevant and examination of observational dataset concluded that it is reasonable and safe to consider early surgical decompression in patients with profound neurologic deficit (ASIA = C) and persistent spinal cord compression due to developmental cervical spinal canal stenosis without fracture or instability. Those with less severe deficit (ASIA = D) can be treated with initial observation with surgery potentially at a later date depending on the extent and temporal profile of the patients neurologic recovery.

journal_name

Spine (Phila Pa 1976)

journal_title

Spine

authors

Lenehan B,Fisher CG,Vaccaro A,Fehlings M,Aarabi B,Dvorak MF

doi

10.1097/BRS.0b013e3181f32a44

subject

Has Abstract

pub_date

2010-10-01 00:00:00

pages

S180-6

issue

21 Suppl

eissn

0362-2436

issn

1528-1159

pii

00007632-201010011-00005

journal_volume

pub_type

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The urgency of surgical decompression in acute central cord injuries with spondylosis and without instability.