Methodology of a nationwide cross-sectional survey of prevalence and epidemiological patterns of hepatitis A, B and C infection in Brazil.

Abstract:

:A population-based survey to provide information on the prevalence of hepatitis viral infection and the pattern of risk factors was carried out in the urban population of all Brazilian state capitals and the Federal District, between 2005 and 2009. This paper describes the design and methodology of the study which involved a population aged 5 to 19 for hepatitis A and 10 to 69 for hepatitis B and C. Interviews and blood samples were obtained through household visits. The sample was selected using stratified multi-stage cluster sampling and was drawn with equal probability from each domain of study (region and age-group). Nationwide, 19,280 households and ~31,000 residents were selected. The study is large enough to detect prevalence of viral infection around 0.1% and risk factor assessments within each region. The methodology seems to be a viable way of differentiating between distinct epidemiological patterns of hepatitis A, B and C. These data will be of value for the evaluation of vaccination policies and for the design of control program strategies.

journal_name

Cad Saude Publica

authors

Ximenes RA,Pereira LM,Martelli CM,Merchán-Hamann E,Stein AT,Figueiredo GM,Braga MC,Montarroyos UR,Brasil LM,Turchi MD,Fonseca JC,Lima ML,Alencar LC,Costa M,Coral G,Moreira RC,Cardoso MR

doi

10.1590/s0102-311x2010000900003

subject

Has Abstract

pub_date

2010-09-01 00:00:00

pages

1693-704

issue

9

eissn

0102-311X

issn

1678-4464

pii

S0102-311X2010000900003

journal_volume

26

pub_type

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