Abstract:
:The Study of Cardiovascular Risk in Adolescents (ERICA) is a pioneering study that aimed to assess the prevalence of cardiovascular risk factors, including metabolic syndrome components in Brazilian adolescents. This study aims to describe the methodological aspects related to blood collection as well as to report pertaining results of the preparation, transport, storage, and exams in ERICA. Exams in ERICA were performed in a single laboratory and blood samples were collected in schools in a standardized manner. Logistics involved air transportation of samples to the reference laboratory with controlled temperature since sample collection. The serum was stored in local biorepositories in four centers to be used in future analyses. During the study, 284,247 exams were performed and rate of participation in exams was 56.2%, thus involving 40,732 adolescents. From the total, 92.6% of the samples reached the reference laboratory maintaining the temperature between 0-10°C. No clinical significant changes in results due to temperature changes were identified. External quality control recorded satisfactory results in 98.7% of the evaluations. Four biorepositories with samples of 7,785 adolescents were created. Thus, we can consider that the logistics adopted in ERICA was fairly successful and description of this as well as the difficulties experienced in Brazil can inform and facilitate the planning of future studies, especially in developing countries.
journal_name
Cad Saude Publicajournal_title
Cadernos de saude publicaauthors
Cureau FV,Bloch KV,Henz A,Schaan CW,Klein CH,Oliveira CL,Giannini DT,Leon EB,Abreu GA,Telo GH,Dias GM,Carvalho KMB,Barufaldi LA,Kuschnir MCC,Szklo M,Montenegro R Jr,Silva TLND,Ekelund U,Schaan BDdoi
10.1590/0102-311X00122816subject
Has Abstractpub_date
2017-05-18 00:00:00pages
e00122816issue
4eissn
0102-311Xissn
1678-4464pii
S0102-311X2017000404001journal_volume
33pub_type
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