Abstract:
:Gentle ovarian stimulation protocols, such as 'mini-IVF', have several potential advantages over conventional IVF protocols, including less medication and fewer injections, producing fewer eggs, but eggs of higher quality. The particular 'mild' stimulation protocol called 'mini-IVF' is described. This protocol requires a reliable and cheap method for embryo cryopreservation such as vitrification, because of the negative impact of clomiphene citrate on the endometrium and since cryopreserved embryo transfers with this protocol have yielded much higher pregnancy rates than fresh transfers. In this series, patients were not denied treatment based on their day-3 FSH value or ovarian reserve. Yet very acceptable pregnancy rates were achieved (20% for fresh embryo transfers and 41% for cryopreserved embryo transfers). These results strengthen the argument for a mini-IVF protocol and vitrification as an alternative to standard conventional IVF stimulation protocols. Now a randomized control trial with cryopreserved single-embryo transfer is required.
journal_name
Reprod Biomed Onlinejournal_title
Reproductive biomedicine onlineauthors
Zhang J,Chang L,Sone Y,Silber Sdoi
10.1016/j.rbmo.2010.06.033subject
Has Abstractpub_date
2010-10-01 00:00:00pages
485-95issue
4eissn
1472-6483issn
1472-6491pii
S1472-6483(10)00442-6journal_volume
21pub_type
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journal_title:Reproductive biomedicine online
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journal_title:Reproductive biomedicine online
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journal_title:Reproductive biomedicine online
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更新日期:2020-05-01 00:00:00
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pub_type: 杂志文章
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journal_title:Reproductive biomedicine online
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更新日期:2012-11-01 00:00:00
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journal_title:Reproductive biomedicine online
pub_type: 评论,杂志文章
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更新日期:2015-10-01 00:00:00
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journal_title:Reproductive biomedicine online
pub_type: 杂志文章
doi:10.1016/S1472-6483(11)60009-6
更新日期:2011-02-01 00:00:00
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journal_title:Reproductive biomedicine online
pub_type: 杂志文章
doi:10.1016/j.rbmo.2017.07.019
更新日期:2017-12-01 00:00:00
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journal_title:Reproductive biomedicine online
pub_type: 杂志文章
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